LeishMANIAdb
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Amastin-like surface protein-like protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Amastin-like surface protein-like protein
Gene product:
amastin-like surface protein-like protein
Species:
Leishmania braziliensis
UniProt:
A4HDL5_LEIBR
TriTrypDb:
LbrM.24.1610 , LBRM2903_240020600 *
Length:
308

Annotations

LeishMANIAdb annotations

Publication identifier(s): 26641088 15760660
Amastin, Kinetoplastid host adhesion protein. A host adhesion protein family greatly expanded in Leishmaniids.. Localization: Cell surface (experimental)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 3
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 20
NetGPI no yes: 0, no: 20
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 19
GO:0110165 cellular anatomical entity 1 19
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Expansion

Sequence features

A4HDL5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HDL5

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 190 192 PF00675 0.467
CLV_PCSK_KEX2_1 190 192 PF00082 0.465
DEG_APCC_DBOX_1 33 41 PF00400 0.571
DEG_Nend_UBRbox_3 1 3 PF02207 0.563
DOC_CKS1_1 149 154 PF01111 0.476
DOC_CKS1_1 156 161 PF01111 0.325
DOC_CKS1_1 55 60 PF01111 0.562
DOC_CYCLIN_yCln2_LP_2 108 114 PF00134 0.552
DOC_MAPK_gen_1 295 305 PF00069 0.529
DOC_MAPK_MEF2A_6 298 305 PF00069 0.536
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Homologs

ProteinTaxonomySequence identityCoverage
A0A381MTC7 Leishmania infantum 28% 100%
A0A3Q8IFH7 Leishmania donovani 28% 100%
A0A3Q8IHZ6 Leishmania donovani 25% 100%
A0A3S7X7E5 Leishmania donovani 26% 100%
A0A3S7X7M4 Leishmania donovani 25% 100%
A0A3S7X7U1 Leishmania donovani 25% 100%
A0A3S7X7W2 Leishmania donovani 27% 100%
A4HDI3 Leishmania braziliensis 39% 100%
A4I0W6 Leishmania infantum 60% 100%
A4I9X0 Leishmania infantum 27% 100%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS