Glycosyltransferase family 61 protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania braziliensis

UniProt:

A4HDJ7_LEIBR

TriTrypDb:

LbrM.24.1430 , LBRM2903_240021600

Length:

360

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HDJ7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HDJ7

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	3
GO:0016740	transferase activity	2	3
GO:0016757	glycosyltransferase activity	3	3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	129	131	PF00675	0.608
CLV_NRD_NRD_1	191	193	PF00675	0.586
CLV_NRD_NRD_1	236	238	PF00675	0.323
CLV_NRD_NRD_1	311	313	PF00675	0.715
CLV_PCSK_KEX2_1	129	131	PF00082	0.608
CLV_PCSK_KEX2_1	191	193	PF00082	0.576
CLV_PCSK_KEX2_1	236	238	PF00082	0.319
CLV_PCSK_KEX2_1	310	312	PF00082	0.709
CLV_PCSK_KEX2_1	41	43	PF00082	0.633
CLV_PCSK_PC1ET2_1	41	43	PF00082	0.577
CLV_PCSK_PC7_1	232	238	PF00082	0.282
CLV_PCSK_SKI1_1	105	109	PF00082	0.558
CLV_PCSK_SKI1_1	315	319	PF00082	0.451
CLV_PCSK_SKI1_1	42	46	PF00082	0.579
DEG_APCC_DBOX_1	236	244	PF00400	0.323
DEG_Nend_UBRbox_4	1	3	PF02207	0.568
DEG_SCF_FBW7_1	18	24	PF00400	0.537
DEG_SPOP_SBC_1	223	227	PF00917	0.282
DOC_CKS1_1	18	23	PF01111	0.588
DOC_CYCLIN_RxL_1	310	319	PF00134	0.481
DOC_MAPK_gen_1	236	243	PF00069	0.319
DOC_MAPK_JIP1_4	237	243	PF00069	0.323
DOC_PP1_RVXF_1	103	110	PF00149	0.562
DOC_PP1_RVXF_1	237	243	PF00149	0.323
DOC_PP1_RVXF_1	259	266	PF00149	0.323
DOC_PP4_FxxP_1	135	138	PF00568	0.579
DOC_PP4_FxxP_1	169	172	PF00568	0.547
DOC_USP7_MATH_1	14	18	PF00917	0.580
DOC_USP7_UBL2_3	41	45	PF12436	0.579
DOC_WW_Pin1_4	138	143	PF00397	0.782
DOC_WW_Pin1_4	17	22	PF00397	0.588
DOC_WW_Pin1_4	244	249	PF00397	0.488
DOC_WW_Pin1_4	346	351	PF00397	0.549
LIG_14-3-3_CanoR_1	232	236	PF00244	0.282
LIG_14-3-3_CanoR_1	312	318	PF00244	0.654
LIG_14-3-3_CanoR_1	77	83	PF00244	0.472
LIG_Actin_WH2_2	28	43	PF00022	0.556
LIG_APCC_ABBA_1	265	270	PF00400	0.323
LIG_BRCT_BRCA1_1	140	144	PF00533	0.578
LIG_CSL_BTD_1	216	219	PF09270	0.323
LIG_eIF4E_1	235	241	PF01652	0.282
LIG_FHA_1	20	26	PF00498	0.649
LIG_FHA_1	208	214	PF00498	0.415
LIG_FHA_1	34	40	PF00498	0.614
LIG_FHA_2	115	121	PF00498	0.512
LIG_FHA_2	314	320	PF00498	0.490
LIG_IRF3_LxIS_1	238	244	PF10401	0.282
LIG_KLC1_Yacidic_2	266	270	PF13176	0.323
LIG_LIR_Apic_2	234	238	PF02991	0.477
LIG_LIR_Gen_1	185	194	PF02991	0.498
LIG_LIR_Gen_1	29	40	PF02991	0.546
LIG_LIR_Gen_1	316	326	PF02991	0.481
LIG_LIR_Nem_3	140	146	PF02991	0.571
LIG_LIR_Nem_3	262	268	PF02991	0.323
LIG_LIR_Nem_3	281	286	PF02991	0.282
LIG_LIR_Nem_3	29	35	PF02991	0.550
LIG_LIR_Nem_3	316	321	PF02991	0.493
LIG_LYPXL_yS_3	46	49	PF13949	0.526
LIG_MLH1_MIPbox_1	140	144	PF16413	0.578
LIG_Pex14_2	165	169	PF04695	0.533
LIG_Pex14_2	87	91	PF04695	0.554
LIG_PTB_Apo_2	192	199	PF02174	0.548
LIG_SH2_CRK	235	239	PF00017	0.282
LIG_SH2_CRK	323	327	PF00017	0.510
LIG_SH2_CRK	9	13	PF00017	0.574
LIG_SH2_GRB2like	28	31	PF00017	0.558
LIG_SH2_STAP1	209	213	PF00017	0.282
LIG_SH2_STAP1	273	277	PF00017	0.282
LIG_SH2_STAP1	28	32	PF00017	0.556
LIG_SH2_STAT3	356	359	PF00017	0.523
LIG_SH2_STAT5	163	166	PF00017	0.528
LIG_SH2_STAT5	209	212	PF00017	0.323
LIG_SH2_STAT5	268	271	PF00017	0.323
LIG_SH2_STAT5	284	287	PF00017	0.323
LIG_SH2_STAT5	67	70	PF00017	0.542
LIG_SH3_3	15	21	PF00018	0.682
LIG_SH3_3	344	350	PF00018	0.505
LIG_SH3_3	41	47	PF00018	0.560
LIG_SUMO_SIM_anti_2	297	302	PF11976	0.282
LIG_TRAF2_1	117	120	PF00917	0.516
LIG_TYR_ITIM	321	326	PF00017	0.499
LIG_TYR_ITIM	44	49	PF00017	0.572
LIG_UBA3_1	256	261	PF00899	0.282
MOD_CDK_SPK_2	244	249	PF00069	0.282
MOD_CK1_1	136	142	PF00069	0.576
MOD_CK1_1	17	23	PF00069	0.580
MOD_CK1_1	244	250	PF00069	0.475
MOD_CK1_1	275	281	PF00069	0.360
MOD_CK2_1	114	120	PF00069	0.520
MOD_CK2_1	275	281	PF00069	0.356
MOD_CK2_1	313	319	PF00069	0.690
MOD_CK2_1	78	84	PF00069	0.512
MOD_GlcNHglycan	172	175	PF01048	0.519
MOD_GlcNHglycan	184	187	PF01048	0.505
MOD_GlcNHglycan	210	213	PF01048	0.290
MOD_GlcNHglycan	277	280	PF01048	0.323
MOD_GlcNHglycan	4	7	PF01048	0.576
MOD_GSK3_1	108	115	PF00069	0.616
MOD_GSK3_1	138	145	PF00069	0.719
MOD_GSK3_1	17	24	PF00069	0.575
MOD_GSK3_1	203	210	PF00069	0.300
MOD_GSK3_1	268	275	PF00069	0.308
MOD_N-GLC_1	14	19	PF02516	0.579
MOD_N-GLC_1	180	185	PF02516	0.530
MOD_N-GLC_1	33	38	PF02516	0.430
MOD_NEK2_1	108	113	PF00069	0.538
MOD_NEK2_1	182	187	PF00069	0.646
MOD_NEK2_1	203	208	PF00069	0.282
MOD_NEK2_1	224	229	PF00069	0.282
MOD_NEK2_1	241	246	PF00069	0.282
MOD_NEK2_1	306	311	PF00069	0.446
MOD_NEK2_1	313	318	PF00069	0.664
MOD_PIKK_1	133	139	PF00454	0.607
MOD_PIKK_1	180	186	PF00454	0.527
MOD_PIKK_1	268	274	PF00454	0.323
MOD_PK_1	255	261	PF00069	0.282
MOD_PKA_2	231	237	PF00069	0.282
MOD_Plk_1	14	20	PF00069	0.579
MOD_Plk_1	203	209	PF00069	0.300
MOD_Plk_4	14	20	PF00069	0.560
MOD_Plk_4	203	209	PF00069	0.292
MOD_Plk_4	67	73	PF00069	0.553
MOD_Plk_4	78	84	PF00069	0.465
MOD_ProDKin_1	138	144	PF00069	0.783
MOD_ProDKin_1	17	23	PF00069	0.588
MOD_ProDKin_1	244	250	PF00069	0.488
MOD_ProDKin_1	346	352	PF00069	0.550
MOD_SUMO_rev_2	247	257	PF00179	0.282
MOD_SUMO_rev_2	92	99	PF00179	0.542
TRG_DiLeu_BaEn_1	281	286	PF01217	0.282
TRG_DiLeu_BaEn_4	84	90	PF01217	0.546
TRG_DiLeu_BaLyEn_6	236	241	PF01217	0.364
TRG_ENDOCYTIC_2	187	190	PF00928	0.539
TRG_ENDOCYTIC_2	28	31	PF00928	0.440
TRG_ENDOCYTIC_2	323	326	PF00928	0.506
TRG_ENDOCYTIC_2	46	49	PF00928	0.444
TRG_ENDOCYTIC_2	69	72	PF00928	0.566
TRG_ENDOCYTIC_2	9	12	PF00928	0.576
TRG_ER_diArg_1	129	131	PF00400	0.625
TRG_ER_diArg_1	190	192	PF00400	0.604
TRG_ER_diArg_1	235	237	PF00400	0.321
TRG_ER_diArg_1	310	312	PF00400	0.678
TRG_Pf-PMV_PEXEL_1	315	319	PF00026	0.687

Homologs


Protein	Taxonomy	Sequence identity	Coverage
E9AWY8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	74%	85%