DNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

DNA helicase

Gene product:

ATP-dependent DEAD/H DNA helicase recQ, putative

Species:

Leishmania braziliensis

UniProt:

A4HDI8_LEIBR

TriTrypDb:

LbrM.24.1330 , LBRM2903_240022900

Length:

2031

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	1
GO:0005694	chromosome	5	1
GO:0005737	cytoplasm	2	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4HDI8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	7
GO:0006259	DNA metabolic process	4	7
GO:0006310	DNA recombination	5	7
GO:0006725	cellular aromatic compound metabolic process	3	7
GO:0006807	nitrogen compound metabolic process	2	7
GO:0008152	metabolic process	1	7
GO:0009987	cellular process	1	7
GO:0034641	cellular nitrogen compound metabolic process	3	7
GO:0043170	macromolecule metabolic process	3	7
GO:0044237	cellular metabolic process	2	7
GO:0044238	primary metabolic process	2	7
GO:0044260	obsolete cellular macromolecule metabolic process	3	7
GO:0046483	heterocycle metabolic process	3	7
GO:0071704	organic substance metabolic process	2	7
GO:0090304	nucleic acid metabolic process	4	7
GO:1901360	organic cyclic compound metabolic process	3	7
GO:0000724	double-strand break repair via homologous recombination	7	1
GO:0000725	recombinational repair	6	1
GO:0006268	DNA unwinding involved in DNA replication	9	1
GO:0006281	DNA repair	5	1
GO:0006302	double-strand break repair	6	1
GO:0006950	response to stress	2	1
GO:0006974	DNA damage response	4	1
GO:0006996	organelle organization	4	1
GO:0016043	cellular component organization	3	1
GO:0032392	DNA geometric change	7	1
GO:0032508	DNA duplex unwinding	8	1
GO:0033554	cellular response to stress	3	1
GO:0050896	response to stimulus	1	1
GO:0051276	chromosome organization	5	1
GO:0051716	cellular response to stimulus	2	1
GO:0071103	DNA conformation change	6	1
GO:0071840	cellular component organization or biogenesis	2	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	7
GO:0003676	nucleic acid binding	3	7
GO:0003824	catalytic activity	1	7
GO:0004386	helicase activity	2	7
GO:0005488	binding	1	7
GO:0005524	ATP binding	5	7
GO:0016787	hydrolase activity	2	7
GO:0017076	purine nucleotide binding	4	7
GO:0030554	adenyl nucleotide binding	5	7
GO:0032553	ribonucleotide binding	3	7
GO:0032555	purine ribonucleotide binding	4	7
GO:0032559	adenyl ribonucleotide binding	5	7
GO:0035639	purine ribonucleoside triphosphate binding	4	7
GO:0036094	small molecule binding	2	7
GO:0043167	ion binding	2	7
GO:0043168	anion binding	3	7
GO:0097159	organic cyclic compound binding	2	7
GO:0097367	carbohydrate derivative binding	2	7
GO:0140640	catalytic activity, acting on a nucleic acid	2	7
GO:0140657	ATP-dependent activity	1	7
GO:1901265	nucleoside phosphate binding	3	7
GO:1901363	heterocyclic compound binding	2	7
GO:0003678	DNA helicase activity	3	1
GO:0008094	ATP-dependent activity, acting on DNA	2	1
GO:0009378	four-way junction helicase activity	4	1
GO:0043138	3'-5' DNA helicase activity	4	1
GO:0140097	catalytic activity, acting on DNA	3	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1044	1048	PF00656	0.437
CLV_C14_Caspase3-7	1092	1096	PF00656	0.597
CLV_C14_Caspase3-7	1196	1200	PF00656	0.680
CLV_C14_Caspase3-7	1297	1301	PF00656	0.762
CLV_C14_Caspase3-7	139	143	PF00656	0.417
CLV_MEL_PAP_1	755	761	PF00089	0.522
CLV_NRD_NRD_1	1130	1132	PF00675	0.425
CLV_NRD_NRD_1	1157	1159	PF00675	0.600
CLV_NRD_NRD_1	1179	1181	PF00675	0.620
CLV_NRD_NRD_1	1188	1190	PF00675	0.564
CLV_NRD_NRD_1	1261	1263	PF00675	0.632
CLV_NRD_NRD_1	1293	1295	PF00675	0.699
CLV_NRD_NRD_1	1543	1545	PF00675	0.673
CLV_NRD_NRD_1	476	478	PF00675	0.612
CLV_NRD_NRD_1	527	529	PF00675	0.474
CLV_NRD_NRD_1	619	621	PF00675	0.346
CLV_NRD_NRD_1	684	686	PF00675	0.346
CLV_NRD_NRD_1	771	773	PF00675	0.346
CLV_NRD_NRD_1	784	786	PF00675	0.346
CLV_NRD_NRD_1	904	906	PF00675	0.346
CLV_PCSK_FUR_1	1541	1545	PF00082	0.769
CLV_PCSK_KEX2_1	1129	1131	PF00082	0.427
CLV_PCSK_KEX2_1	1157	1159	PF00082	0.647
CLV_PCSK_KEX2_1	1179	1181	PF00082	0.619
CLV_PCSK_KEX2_1	1188	1190	PF00082	0.562
CLV_PCSK_KEX2_1	1261	1263	PF00082	0.632
CLV_PCSK_KEX2_1	1295	1297	PF00082	0.683
CLV_PCSK_KEX2_1	1397	1399	PF00082	0.346
CLV_PCSK_KEX2_1	1543	1545	PF00082	0.673
CLV_PCSK_KEX2_1	527	529	PF00082	0.474
CLV_PCSK_KEX2_1	619	621	PF00082	0.311
CLV_PCSK_KEX2_1	691	693	PF00082	0.419
CLV_PCSK_KEX2_1	784	786	PF00082	0.346
CLV_PCSK_KEX2_1	903	905	PF00082	0.346
CLV_PCSK_PC1ET2_1	1129	1131	PF00082	0.385
CLV_PCSK_PC1ET2_1	1179	1181	PF00082	0.664
CLV_PCSK_PC1ET2_1	1295	1297	PF00082	0.683
CLV_PCSK_PC1ET2_1	1397	1399	PF00082	0.346
CLV_PCSK_PC1ET2_1	691	693	PF00082	0.419
CLV_PCSK_SKI1_1	1026	1030	PF00082	0.443
CLV_PCSK_SKI1_1	1031	1035	PF00082	0.408
CLV_PCSK_SKI1_1	1078	1082	PF00082	0.551
CLV_PCSK_SKI1_1	1169	1173	PF00082	0.549
CLV_PCSK_SKI1_1	1183	1187	PF00082	0.609
CLV_PCSK_SKI1_1	1305	1309	PF00082	0.415
CLV_PCSK_SKI1_1	1335	1339	PF00082	0.517
CLV_PCSK_SKI1_1	1430	1434	PF00082	0.611
CLV_PCSK_SKI1_1	1499	1503	PF00082	0.740
CLV_PCSK_SKI1_1	496	500	PF00082	0.593
CLV_PCSK_SKI1_1	531	535	PF00082	0.452
CLV_PCSK_SKI1_1	554	558	PF00082	0.346
CLV_PCSK_SKI1_1	620	624	PF00082	0.346
CLV_PCSK_SKI1_1	659	663	PF00082	0.324
CLV_PCSK_SKI1_1	785	789	PF00082	0.333
DEG_APCC_DBOX_1	1030	1038	PF00400	0.467
DEG_APCC_DBOX_1	292	300	PF00400	0.668
DEG_APCC_DBOX_1	807	815	PF00400	0.546
DEG_APCC_DBOX_1	882	890	PF00400	0.546
DEG_SPOP_SBC_1	1702	1706	PF00917	0.431
DEG_SPOP_SBC_1	2	6	PF00917	0.580
DEG_SPOP_SBC_1	230	234	PF00917	0.566
DEG_SPOP_SBC_1	27	31	PF00917	0.458
DEG_SPOP_SBC_1	338	342	PF00917	0.514
DOC_CKS1_1	1235	1240	PF01111	0.646
DOC_CKS1_1	1640	1645	PF01111	0.565
DOC_CKS1_1	1675	1680	PF01111	0.600
DOC_CKS1_1	1894	1899	PF01111	0.521
DOC_CKS1_1	637	642	PF01111	0.546
DOC_CKS1_1	695	700	PF01111	0.546
DOC_CKS1_1	88	93	PF01111	0.553
DOC_CYCLIN_RxL_1	1023	1032	PF00134	0.446
DOC_CYCLIN_RxL_1	1330	1341	PF00134	0.525
DOC_CYCLIN_RxL_1	617	625	PF00134	0.546
DOC_CYCLIN_yCln2_LP_2	405	411	PF00134	0.487
DOC_MAPK_gen_1	1330	1338	PF00069	0.412
DOC_MAPK_gen_1	1405	1415	PF00069	0.607
DOC_MAPK_gen_1	743	750	PF00069	0.550
DOC_MAPK_gen_1	805	813	PF00069	0.546
DOC_MAPK_MEF2A_6	1330	1338	PF00069	0.412
DOC_MAPK_MEF2A_6	1567	1575	PF00069	0.678
DOC_MAPK_MEF2A_6	501	509	PF00069	0.574
DOC_PP2B_LxvP_1	1374	1377	PF13499	0.546
DOC_PP2B_LxvP_1	260	263	PF13499	0.433
DOC_PP4_FxxP_1	1648	1651	PF00568	0.668
DOC_PP4_FxxP_1	1653	1656	PF00568	0.621
DOC_PP4_FxxP_1	1894	1897	PF00568	0.396
DOC_PP4_MxPP_1	239	242	PF00568	0.521
DOC_PP4_MxPP_1	251	254	PF00568	0.420
DOC_PP4_MxPP_1	42	45	PF00568	0.413
DOC_SPAK_OSR1_1	326	330	PF12202	0.405
DOC_SPAK_OSR1_1	664	668	PF12202	0.546
DOC_USP7_MATH_1	10	14	PF00917	0.614
DOC_USP7_MATH_1	1022	1026	PF00917	0.590
DOC_USP7_MATH_1	1133	1137	PF00917	0.486
DOC_USP7_MATH_1	1198	1202	PF00917	0.719
DOC_USP7_MATH_1	1445	1449	PF00917	0.689
DOC_USP7_MATH_1	1511	1515	PF00917	0.768
DOC_USP7_MATH_1	1671	1675	PF00917	0.692
DOC_USP7_MATH_1	1700	1704	PF00917	0.543
DOC_USP7_MATH_1	1742	1746	PF00917	0.638
DOC_USP7_MATH_1	1760	1764	PF00917	0.451
DOC_USP7_MATH_1	1832	1836	PF00917	0.620
DOC_USP7_MATH_1	1868	1872	PF00917	0.574
DOC_USP7_MATH_1	1913	1917	PF00917	0.686
DOC_USP7_MATH_1	1968	1972	PF00917	0.634
DOC_USP7_MATH_1	206	210	PF00917	0.637
DOC_USP7_MATH_1	229	233	PF00917	0.496
DOC_USP7_MATH_1	242	246	PF00917	0.537
DOC_USP7_MATH_1	254	258	PF00917	0.469
DOC_USP7_MATH_1	37	41	PF00917	0.420
DOC_USP7_MATH_1	389	393	PF00917	0.531
DOC_USP7_MATH_1	409	413	PF00917	0.531
DOC_USP7_MATH_1	56	60	PF00917	0.467
DOC_USP7_MATH_1	618	622	PF00917	0.546
DOC_USP7_MATH_1	941	945	PF00917	0.611
DOC_USP7_MATH_1	984	988	PF00917	0.341
DOC_USP7_UBL2_3	1019	1023	PF12436	0.644
DOC_USP7_UBL2_3	1179	1183	PF12436	0.721
DOC_USP7_UBL2_3	1393	1397	PF12436	0.546
DOC_WW_Pin1_4	1011	1016	PF00397	0.669
DOC_WW_Pin1_4	1060	1065	PF00397	0.492
DOC_WW_Pin1_4	1106	1111	PF00397	0.387
DOC_WW_Pin1_4	1234	1239	PF00397	0.629
DOC_WW_Pin1_4	1243	1248	PF00397	0.649
DOC_WW_Pin1_4	1318	1323	PF00397	0.430
DOC_WW_Pin1_4	1471	1476	PF00397	0.532
DOC_WW_Pin1_4	1504	1509	PF00397	0.642
DOC_WW_Pin1_4	1518	1523	PF00397	0.674
DOC_WW_Pin1_4	1567	1572	PF00397	0.684
DOC_WW_Pin1_4	1639	1644	PF00397	0.567
DOC_WW_Pin1_4	1674	1679	PF00397	0.643
DOC_WW_Pin1_4	1696	1701	PF00397	0.495
DOC_WW_Pin1_4	176	181	PF00397	0.586
DOC_WW_Pin1_4	1773	1778	PF00397	0.698
DOC_WW_Pin1_4	1866	1871	PF00397	0.570
DOC_WW_Pin1_4	1893	1898	PF00397	0.546
DOC_WW_Pin1_4	1959	1964	PF00397	0.573
DOC_WW_Pin1_4	1978	1983	PF00397	0.667
DOC_WW_Pin1_4	219	224	PF00397	0.500
DOC_WW_Pin1_4	265	270	PF00397	0.634
DOC_WW_Pin1_4	340	345	PF00397	0.674
DOC_WW_Pin1_4	357	362	PF00397	0.538
DOC_WW_Pin1_4	40	45	PF00397	0.447
DOC_WW_Pin1_4	414	419	PF00397	0.637
DOC_WW_Pin1_4	445	450	PF00397	0.461
DOC_WW_Pin1_4	460	465	PF00397	0.445
DOC_WW_Pin1_4	584	589	PF00397	0.538
DOC_WW_Pin1_4	636	641	PF00397	0.546
DOC_WW_Pin1_4	694	699	PF00397	0.546
DOC_WW_Pin1_4	757	762	PF00397	0.519
DOC_WW_Pin1_4	87	92	PF00397	0.695
LIG_14-3-3_CanoR_1	1078	1083	PF00244	0.650
LIG_14-3-3_CanoR_1	1261	1267	PF00244	0.584
LIG_14-3-3_CanoR_1	1314	1322	PF00244	0.423
LIG_14-3-3_CanoR_1	1344	1350	PF00244	0.619
LIG_14-3-3_CanoR_1	1369	1377	PF00244	0.546
LIG_14-3-3_CanoR_1	1444	1454	PF00244	0.694
LIG_14-3-3_CanoR_1	1468	1478	PF00244	0.668
LIG_14-3-3_CanoR_1	1512	1522	PF00244	0.680
LIG_14-3-3_CanoR_1	1541	1549	PF00244	0.676
LIG_14-3-3_CanoR_1	1833	1840	PF00244	0.477
LIG_14-3-3_CanoR_1	190	198	PF00244	0.584
LIG_14-3-3_CanoR_1	1950	1955	PF00244	0.532
LIG_14-3-3_CanoR_1	1997	2001	PF00244	0.563
LIG_14-3-3_CanoR_1	246	252	PF00244	0.736
LIG_14-3-3_CanoR_1	26	36	PF00244	0.437
LIG_14-3-3_CanoR_1	326	335	PF00244	0.437
LIG_14-3-3_CanoR_1	337	347	PF00244	0.476
LIG_14-3-3_CanoR_1	477	483	PF00244	0.641
LIG_14-3-3_CanoR_1	519	529	PF00244	0.465
LIG_14-3-3_CanoR_1	619	623	PF00244	0.546
LIG_14-3-3_CanoR_1	685	690	PF00244	0.546
LIG_14-3-3_CanoR_1	883	893	PF00244	0.546
LIG_14-3-3_CanoR_1	995	1005	PF00244	0.487
LIG_Actin_WH2_2	272	289	PF00022	0.541
LIG_Actin_WH2_2	707	723	PF00022	0.574
LIG_Actin_WH2_2	965	983	PF00022	0.424
LIG_APCC_ABBA_1	1039	1044	PF00400	0.436
LIG_APCC_ABBA_1	1650	1655	PF00400	0.605
LIG_APCC_ABBAyCdc20_2	619	625	PF00400	0.546
LIG_BRCT_BRCA1_1	1957	1961	PF00533	0.627
LIG_BRCT_BRCA1_1	462	466	PF00533	0.431
LIG_BRCT_BRCA1_1	645	649	PF00533	0.546
LIG_CaM_NSCaTE_8	53	60	PF13499	0.424
LIG_Clathr_ClatBox_1	1385	1389	PF01394	0.619
LIG_Clathr_ClatBox_1	296	300	PF01394	0.696
LIG_CtBP_PxDLS_1	173	177	PF00389	0.622
LIG_EH1_1	629	637	PF00400	0.619
LIG_eIF4E_1	570	576	PF01652	0.546
LIG_EVH1_1	1653	1657	PF00568	0.617
LIG_FHA_1	1079	1085	PF00498	0.581
LIG_FHA_1	1117	1123	PF00498	0.392
LIG_FHA_1	1166	1172	PF00498	0.460
LIG_FHA_1	119	125	PF00498	0.369
LIG_FHA_1	1369	1375	PF00498	0.546
LIG_FHA_1	1486	1492	PF00498	0.464
LIG_FHA_1	1663	1669	PF00498	0.450
LIG_FHA_1	225	231	PF00498	0.468
LIG_FHA_1	400	406	PF00498	0.500
LIG_FHA_1	500	506	PF00498	0.574
LIG_FHA_1	56	62	PF00498	0.467
LIG_FHA_1	581	587	PF00498	0.546
LIG_FHA_1	705	711	PF00498	0.546
LIG_FHA_1	715	721	PF00498	0.434
LIG_FHA_2	1012	1018	PF00498	0.566
LIG_FHA_2	1030	1036	PF00498	0.469
LIG_FHA_2	1087	1093	PF00498	0.405
LIG_FHA_2	1200	1206	PF00498	0.602
LIG_FHA_2	1276	1282	PF00498	0.745
LIG_FHA_2	1295	1301	PF00498	0.769
LIG_FHA_2	1533	1539	PF00498	0.793
LIG_FHA_2	2023	2029	PF00498	0.719
LIG_FHA_2	269	275	PF00498	0.534
LIG_FHA_2	431	437	PF00498	0.576
LIG_FHA_2	703	709	PF00498	0.546
LIG_FHA_2	805	811	PF00498	0.509
LIG_FHA_2	863	869	PF00498	0.642
LIG_FHA_2	88	94	PF00498	0.613
LIG_FHA_2	894	900	PF00498	0.520
LIG_FHA_2	960	966	PF00498	0.489
LIG_Integrin_RGD_1	1093	1095	PF01839	0.419
LIG_Integrin_RGD_1	1298	1300	PF01839	0.763
LIG_LIR_Apic_2	167	171	PF02991	0.603
LIG_LIR_Apic_2	1674	1678	PF02991	0.644
LIG_LIR_Apic_2	1891	1897	PF02991	0.392
LIG_LIR_Apic_2	468	474	PF02991	0.405
LIG_LIR_Apic_2	567	573	PF02991	0.546
LIG_LIR_Apic_2	634	640	PF02991	0.546
LIG_LIR_Gen_1	108	116	PF02991	0.376
LIG_LIR_Gen_1	1095	1105	PF02991	0.412
LIG_LIR_Gen_1	1358	1367	PF02991	0.546
LIG_LIR_Gen_1	1569	1579	PF02991	0.438
LIG_LIR_Gen_1	1602	1611	PF02991	0.640
LIG_LIR_Gen_1	321	332	PF02991	0.551
LIG_LIR_Gen_1	538	549	PF02991	0.507
LIG_LIR_Gen_1	555	561	PF02991	0.438
LIG_LIR_Gen_1	595	606	PF02991	0.546
LIG_LIR_Gen_1	974	984	PF02991	0.523
LIG_LIR_Nem_3	108	112	PF02991	0.445
LIG_LIR_Nem_3	1095	1101	PF02991	0.652
LIG_LIR_Nem_3	1569	1575	PF02991	0.427
LIG_LIR_Nem_3	1602	1607	PF02991	0.634
LIG_LIR_Nem_3	321	327	PF02991	0.535
LIG_LIR_Nem_3	33	38	PF02991	0.660
LIG_LIR_Nem_3	481	485	PF02991	0.562
LIG_LIR_Nem_3	538	544	PF02991	0.529
LIG_LIR_Nem_3	555	560	PF02991	0.438
LIG_LIR_Nem_3	595	601	PF02991	0.546
LIG_LIR_Nem_3	683	687	PF02991	0.513
LIG_LIR_Nem_3	760	766	PF02991	0.288
LIG_LIR_Nem_3	974	979	PF02991	0.510
LIG_LYPXL_S_1	132	136	PF13949	0.566
LIG_LYPXL_S_1	34	38	PF13949	0.421
LIG_LYPXL_yS_3	133	136	PF13949	0.567
LIG_LYPXL_yS_3	35	38	PF13949	0.419
LIG_MYND_1	1585	1589	PF01753	0.756
LIG_MYND_1	573	577	PF01753	0.546
LIG_MYND_1	933	937	PF01753	0.619
LIG_NRBOX	1333	1339	PF00104	0.525
LIG_PCNA_PIPBox_1	1987	1996	PF02747	0.558
LIG_PCNA_yPIPBox_3	1333	1346	PF02747	0.512
LIG_PCNA_yPIPBox_3	1987	1997	PF02747	0.559
LIG_PCNA_yPIPBox_3	211	219	PF02747	0.445
LIG_Pex14_1	676	680	PF04695	0.546
LIG_Pex14_2	726	730	PF04695	0.429
LIG_Pex14_2	759	763	PF04695	0.285
LIG_PROFILIN_1	1680	1686	PF00235	0.580
LIG_Rb_pABgroove_1	1147	1155	PF01858	0.538
LIG_SH2_CRK	109	113	PF00017	0.425
LIG_SH2_CRK	1604	1608	PF00017	0.637
LIG_SH2_CRK	168	172	PF00017	0.594
LIG_SH2_CRK	471	475	PF00017	0.381
LIG_SH2_CRK	570	574	PF00017	0.546
LIG_SH2_CRK	598	602	PF00017	0.546
LIG_SH2_CRK	684	688	PF00017	0.546
LIG_SH2_CRK	976	980	PF00017	0.524
LIG_SH2_NCK_1	168	172	PF00017	0.594
LIG_SH2_NCK_1	371	375	PF00017	0.544
LIG_SH2_NCK_1	471	475	PF00017	0.381
LIG_SH2_NCK_1	598	602	PF00017	0.546
LIG_SH2_PTP2	1412	1415	PF00017	0.567
LIG_SH2_PTP2	637	640	PF00017	0.546
LIG_SH2_SRC	1412	1415	PF00017	0.465
LIG_SH2_SRC	1494	1497	PF00017	0.447
LIG_SH2_SRC	168	171	PF00017	0.606
LIG_SH2_SRC	845	848	PF00017	0.598
LIG_SH2_SRC	976	979	PF00017	0.524
LIG_SH2_STAP1	1739	1743	PF00017	0.450
LIG_SH2_STAP1	371	375	PF00017	0.428
LIG_SH2_STAP1	485	489	PF00017	0.560
LIG_SH2_STAP1	598	602	PF00017	0.546
LIG_SH2_STAP1	976	980	PF00017	0.524
LIG_SH2_STAT3	485	488	PF00017	0.561
LIG_SH2_STAT3	737	740	PF00017	0.497
LIG_SH2_STAT5	116	119	PF00017	0.395
LIG_SH2_STAT5	1193	1196	PF00017	0.650
LIG_SH2_STAT5	1412	1415	PF00017	0.465
LIG_SH2_STAT5	1789	1792	PF00017	0.623
LIG_SH2_STAT5	1884	1887	PF00017	0.657
LIG_SH2_STAT5	2024	2027	PF00017	0.572
LIG_SH2_STAT5	46	49	PF00017	0.416
LIG_SH2_STAT5	637	640	PF00017	0.504
LIG_SH2_STAT5	642	645	PF00017	0.504
LIG_SH2_STAT5	768	771	PF00017	0.546
LIG_SH2_STAT5	831	834	PF00017	0.546
LIG_SH2_STAT5	895	898	PF00017	0.546
LIG_SH3_1	168	174	PF00018	0.488
LIG_SH3_1	1721	1727	PF00018	0.703
LIG_SH3_1	692	698	PF00018	0.549
LIG_SH3_3	121	127	PF00018	0.485
LIG_SH3_3	1232	1238	PF00018	0.584
LIG_SH3_3	1286	1292	PF00018	0.810
LIG_SH3_3	1432	1438	PF00018	0.519
LIG_SH3_3	1527	1533	PF00018	0.741
LIG_SH3_3	1565	1571	PF00018	0.459
LIG_SH3_3	1582	1588	PF00018	0.670
LIG_SH3_3	1631	1637	PF00018	0.797
LIG_SH3_3	1638	1644	PF00018	0.715
LIG_SH3_3	1648	1654	PF00018	0.614
LIG_SH3_3	167	173	PF00018	0.646
LIG_SH3_3	1675	1681	PF00018	0.573
LIG_SH3_3	1721	1727	PF00018	0.703
LIG_SH3_3	1826	1832	PF00018	0.699
LIG_SH3_3	1937	1943	PF00018	0.638
LIG_SH3_3	1982	1988	PF00018	0.583
LIG_SH3_3	234	240	PF00018	0.585
LIG_SH3_3	352	358	PF00018	0.593
LIG_SH3_3	405	411	PF00018	0.582
LIG_SH3_3	502	508	PF00018	0.574
LIG_SH3_3	555	561	PF00018	0.546
LIG_SH3_3	582	588	PF00018	0.546
LIG_SH3_3	692	698	PF00018	0.526
LIG_SH3_3	930	936	PF00018	0.548
LIG_SUMO_SIM_anti_2	294	303	PF11976	0.654
LIG_SUMO_SIM_par_1	1384	1389	PF11976	0.619
LIG_SUMO_SIM_par_1	1816	1824	PF11976	0.487
LIG_SUMO_SIM_par_1	268	274	PF11976	0.532
LIG_SUMO_SIM_par_1	294	303	PF11976	0.654
LIG_SUMO_SIM_par_1	582	587	PF11976	0.546
LIG_SUMO_SIM_par_1	746	753	PF11976	0.325
LIG_TRAF2_1	1211	1214	PF00917	0.723
LIG_TRAF2_1	2002	2005	PF00917	0.573
LIG_TRFH_1	557	561	PF08558	0.546
LIG_UBA3_1	1385	1393	PF00899	0.619
LIG_WRC_WIRS_1	1222	1227	PF05994	0.619
LIG_WW_2	1585	1588	PF00397	0.755
LIG_WW_3	1291	1295	PF00397	0.809
MOD_CDC14_SPxK_1	1109	1112	PF00782	0.397
MOD_CDC14_SPxK_1	1869	1872	PF00782	0.575
MOD_CDK_SPxK_1	1106	1112	PF00069	0.389
MOD_CDK_SPxK_1	1243	1249	PF00069	0.647
MOD_CDK_SPxK_1	1504	1510	PF00069	0.640
MOD_CDK_SPxK_1	1518	1524	PF00069	0.672
MOD_CDK_SPxK_1	1866	1872	PF00069	0.570
MOD_CK1_1	1136	1142	PF00069	0.635
MOD_CK1_1	1216	1222	PF00069	0.609
MOD_CK1_1	1230	1236	PF00069	0.551
MOD_CK1_1	1242	1248	PF00069	0.670
MOD_CK1_1	1268	1274	PF00069	0.605
MOD_CK1_1	1277	1283	PF00069	0.682
MOD_CK1_1	1315	1321	PF00069	0.424
MOD_CK1_1	1471	1477	PF00069	0.531
MOD_CK1_1	150	156	PF00069	0.596
MOD_CK1_1	1514	1520	PF00069	0.695
MOD_CK1_1	1550	1556	PF00069	0.680
MOD_CK1_1	161	167	PF00069	0.499
MOD_CK1_1	1674	1680	PF00069	0.710
MOD_CK1_1	1701	1707	PF00069	0.688
MOD_CK1_1	1763	1769	PF00069	0.506
MOD_CK1_1	1844	1850	PF00069	0.543
MOD_CK1_1	1953	1959	PF00069	0.675
MOD_CK1_1	1999	2005	PF00069	0.569
MOD_CK1_1	268	274	PF00069	0.527
MOD_CK1_1	28	34	PF00069	0.565
MOD_CK1_1	340	346	PF00069	0.679
MOD_CK1_1	349	355	PF00069	0.616
MOD_CK1_1	40	46	PF00069	0.422
MOD_CK1_1	412	418	PF00069	0.564
MOD_CK1_1	465	471	PF00069	0.574
MOD_CK1_1	472	478	PF00069	0.510
MOD_CK1_1	55	61	PF00069	0.384
MOD_CK1_1	6	12	PF00069	0.601
MOD_CK1_1	864	870	PF00069	0.411
MOD_CK1_1	885	891	PF00069	0.546
MOD_CK1_1	939	945	PF00069	0.598
MOD_CK2_1	1011	1017	PF00069	0.637
MOD_CK2_1	1029	1035	PF00069	0.278
MOD_CK2_1	1207	1213	PF00069	0.654
MOD_CK2_1	1275	1281	PF00069	0.744
MOD_CK2_1	1419	1425	PF00069	0.553
MOD_CK2_1	1445	1451	PF00069	0.693
MOD_CK2_1	1967	1973	PF00069	0.631
MOD_CK2_1	1999	2005	PF00069	0.569
MOD_CK2_1	430	436	PF00069	0.582
MOD_CK2_1	464	470	PF00069	0.470
MOD_CK2_1	746	752	PF00069	0.326
MOD_CK2_1	795	801	PF00069	0.526
MOD_CK2_1	804	810	PF00069	0.489
MOD_CK2_1	959	965	PF00069	0.467
MOD_Cter_Amidation	1127	1130	PF01082	0.385
MOD_Cter_Amidation	1186	1189	PF01082	0.737
MOD_Cter_Amidation	1259	1262	PF01082	0.711
MOD_DYRK1A_RPxSP_1	1567	1571	PF00069	0.672
MOD_GlcNHglycan	1101	1104	PF01048	0.529
MOD_GlcNHglycan	1135	1138	PF01048	0.641
MOD_GlcNHglycan	1164	1168	PF01048	0.595
MOD_GlcNHglycan	12	15	PF01048	0.630
MOD_GlcNHglycan	1213	1218	PF01048	0.688
MOD_GlcNHglycan	1232	1235	PF01048	0.373
MOD_GlcNHglycan	1242	1245	PF01048	0.542
MOD_GlcNHglycan	1267	1270	PF01048	0.689
MOD_GlcNHglycan	1314	1317	PF01048	0.443
MOD_GlcNHglycan	1425	1428	PF01048	0.679
MOD_GlcNHglycan	1447	1450	PF01048	0.606
MOD_GlcNHglycan	1462	1465	PF01048	0.722
MOD_GlcNHglycan	149	152	PF01048	0.620
MOD_GlcNHglycan	1517	1520	PF01048	0.779
MOD_GlcNHglycan	1527	1530	PF01048	0.620
MOD_GlcNHglycan	1625	1628	PF01048	0.526
MOD_GlcNHglycan	1700	1703	PF01048	0.661
MOD_GlcNHglycan	1705	1708	PF01048	0.624
MOD_GlcNHglycan	1713	1716	PF01048	0.566
MOD_GlcNHglycan	1744	1747	PF01048	0.669
MOD_GlcNHglycan	1755	1758	PF01048	0.698
MOD_GlcNHglycan	1800	1803	PF01048	0.704
MOD_GlcNHglycan	1842	1846	PF01048	0.523
MOD_GlcNHglycan	1898	1901	PF01048	0.667
MOD_GlcNHglycan	1915	1918	PF01048	0.582
MOD_GlcNHglycan	1928	1931	PF01048	0.549
MOD_GlcNHglycan	1955	1958	PF01048	0.675
MOD_GlcNHglycan	1970	1973	PF01048	0.597
MOD_GlcNHglycan	212	215	PF01048	0.495
MOD_GlcNHglycan	257	260	PF01048	0.551
MOD_GlcNHglycan	30	33	PF01048	0.385
MOD_GlcNHglycan	372	375	PF01048	0.608
MOD_GlcNHglycan	412	415	PF01048	0.749
MOD_GlcNHglycan	441	444	PF01048	0.448
MOD_GlcNHglycan	467	470	PF01048	0.588
MOD_GlcNHglycan	474	477	PF01048	0.530
MOD_GlcNHglycan	54	57	PF01048	0.636
MOD_GlcNHglycan	58	61	PF01048	0.565
MOD_GlcNHglycan	627	630	PF01048	0.331
MOD_GlcNHglycan	8	11	PF01048	0.620
MOD_GlcNHglycan	847	850	PF01048	0.346
MOD_GlcNHglycan	941	944	PF01048	0.321
MOD_GSK3_1	1	8	PF00069	0.598
MOD_GSK3_1	1136	1143	PF00069	0.376
MOD_GSK3_1	1230	1237	PF00069	0.541
MOD_GSK3_1	1239	1246	PF00069	0.606
MOD_GSK3_1	1264	1271	PF00069	0.613
MOD_GSK3_1	1318	1325	PF00069	0.426
MOD_GSK3_1	1419	1426	PF00069	0.407
MOD_GSK3_1	147	154	PF00069	0.553
MOD_GSK3_1	1511	1518	PF00069	0.673
MOD_GSK3_1	1543	1550	PF00069	0.660
MOD_GSK3_1	1567	1574	PF00069	0.578
MOD_GSK3_1	1605	1612	PF00069	0.544
MOD_GSK3_1	1696	1703	PF00069	0.564
MOD_GSK3_1	172	179	PF00069	0.611
MOD_GSK3_1	1742	1749	PF00069	0.614
MOD_GSK3_1	1773	1780	PF00069	0.685
MOD_GSK3_1	1819	1826	PF00069	0.538
MOD_GSK3_1	189	196	PF00069	0.408
MOD_GSK3_1	1896	1903	PF00069	0.580
MOD_GSK3_1	1922	1929	PF00069	0.692
MOD_GSK3_1	1955	1962	PF00069	0.649
MOD_GSK3_1	1964	1971	PF00069	0.649
MOD_GSK3_1	1977	1984	PF00069	0.588
MOD_GSK3_1	201	208	PF00069	0.467
MOD_GSK3_1	225	232	PF00069	0.535
MOD_GSK3_1	26	33	PF00069	0.441
MOD_GSK3_1	336	343	PF00069	0.658
MOD_GSK3_1	345	352	PF00069	0.663
MOD_GSK3_1	410	417	PF00069	0.613
MOD_GSK3_1	435	442	PF00069	0.480
MOD_GSK3_1	445	452	PF00069	0.490
MOD_GSK3_1	460	467	PF00069	0.611
MOD_GSK3_1	48	55	PF00069	0.423
MOD_GSK3_1	580	587	PF00069	0.546
MOD_GSK3_1	700	707	PF00069	0.524
MOD_GSK3_1	787	794	PF00069	0.546
MOD_GSK3_1	935	942	PF00069	0.542
MOD_N-GLC_1	1239	1244	PF02516	0.520
MOD_N-GLC_1	1445	1450	PF02516	0.691
MOD_N-GLC_1	158	163	PF02516	0.531
MOD_N-GLC_1	369	374	PF02516	0.440
MOD_N-GLC_1	439	444	PF02516	0.486
MOD_N-GLC_1	48	53	PF02516	0.529
MOD_N-GLC_1	966	971	PF02516	0.276
MOD_N-GLC_2	548	550	PF02516	0.346
MOD_NEK2_1	1029	1034	PF00069	0.581
MOD_NEK2_1	1153	1158	PF00069	0.643
MOD_NEK2_1	118	123	PF00069	0.469
MOD_NEK2_1	1218	1223	PF00069	0.687
MOD_NEK2_1	1239	1244	PF00069	0.591
MOD_NEK2_1	1345	1350	PF00069	0.546
MOD_NEK2_1	136	141	PF00069	0.418
MOD_NEK2_1	1370	1375	PF00069	0.546
MOD_NEK2_1	1391	1396	PF00069	0.438
MOD_NEK2_1	1502	1507	PF00069	0.496
MOD_NEK2_1	1547	1552	PF00069	0.585
MOD_NEK2_1	1711	1716	PF00069	0.640
MOD_NEK2_1	1734	1739	PF00069	0.656
MOD_NEK2_1	1750	1755	PF00069	0.653
MOD_NEK2_1	1772	1777	PF00069	0.699
MOD_NEK2_1	1843	1848	PF00069	0.452
MOD_NEK2_1	1976	1981	PF00069	0.595
MOD_NEK2_1	210	215	PF00069	0.490
MOD_NEK2_1	218	223	PF00069	0.552
MOD_NEK2_1	327	332	PF00069	0.524
MOD_NEK2_1	398	403	PF00069	0.758
MOD_NEK2_1	499	504	PF00069	0.576
MOD_NEK2_1	608	613	PF00069	0.546
MOD_NEK2_1	649	654	PF00069	0.546
MOD_NEK2_1	702	707	PF00069	0.546
MOD_NEK2_1	726	731	PF00069	0.429
MOD_NEK2_1	735	740	PF00069	0.471
MOD_NEK2_1	862	867	PF00069	0.550
MOD_NEK2_1	893	898	PF00069	0.546
MOD_NEK2_1	919	924	PF00069	0.546
MOD_NEK2_2	206	211	PF00069	0.481
MOD_NEK2_2	618	623	PF00069	0.546
MOD_PIKK_1	1268	1274	PF00454	0.742
MOD_PIKK_1	1280	1286	PF00454	0.563
MOD_PIKK_1	1348	1354	PF00454	0.619
MOD_PIKK_1	1777	1783	PF00454	0.647
MOD_PIKK_1	1823	1829	PF00454	0.627
MOD_PIKK_1	1996	2002	PF00454	0.594
MOD_PIKK_1	327	333	PF00454	0.454
MOD_PIKK_1	671	677	PF00454	0.546
MOD_PIKK_1	79	85	PF00454	0.596
MOD_PIKK_1	919	925	PF00454	0.546
MOD_PIKK_1	944	950	PF00454	0.522
MOD_PK_1	1045	1051	PF00069	0.431
MOD_PK_1	359	365	PF00069	0.509
MOD_PK_1	685	691	PF00069	0.546
MOD_PKA_1	1294	1300	PF00069	0.676
MOD_PKA_1	1543	1549	PF00069	0.549
MOD_PKA_1	685	691	PF00069	0.514
MOD_PKA_2	1368	1374	PF00069	0.546
MOD_PKA_2	1511	1517	PF00069	0.778
MOD_PKA_2	1542	1548	PF00069	0.671
MOD_PKA_2	1566	1572	PF00069	0.608
MOD_PKA_2	1811	1817	PF00069	0.615
MOD_PKA_2	1832	1838	PF00069	0.482
MOD_PKA_2	189	195	PF00069	0.489
MOD_PKA_2	1900	1906	PF00069	0.666
MOD_PKA_2	1996	2002	PF00069	0.564
MOD_PKA_2	210	216	PF00069	0.426
MOD_PKA_2	25	31	PF00069	0.446
MOD_PKA_2	327	333	PF00069	0.454
MOD_PKA_2	336	342	PF00069	0.536
MOD_PKA_2	618	624	PF00069	0.546
MOD_PKA_2	804	810	PF00069	0.546
MOD_PKA_2	882	888	PF00069	0.504
MOD_PKA_2	99	105	PF00069	0.548
MOD_PKA_2	994	1000	PF00069	0.494
MOD_PKB_1	1262	1270	PF00069	0.608
MOD_PKB_1	1541	1549	PF00069	0.517
MOD_Plk_1	1029	1035	PF00069	0.576
MOD_Plk_1	1213	1219	PF00069	0.603
MOD_Plk_1	161	167	PF00069	0.544
MOD_Plk_1	1617	1623	PF00069	0.446
MOD_Plk_1	435	441	PF00069	0.664
MOD_Plk_1	455	461	PF00069	0.368
MOD_Plk_1	469	475	PF00069	0.413
MOD_Plk_2-3	1199	1205	PF00069	0.619
MOD_Plk_2-3	1419	1425	PF00069	0.553
MOD_Plk_2-3	1878	1884	PF00069	0.588
MOD_Plk_2-3	2022	2028	PF00069	0.722
MOD_Plk_2-3	959	965	PF00069	0.467
MOD_Plk_4	119	125	PF00069	0.369
MOD_Plk_4	1221	1227	PF00069	0.617
MOD_Plk_4	1345	1351	PF00069	0.546
MOD_Plk_4	1363	1369	PF00069	0.546
MOD_Plk_4	1431	1437	PF00069	0.496
MOD_Plk_4	1617	1623	PF00069	0.440
MOD_Plk_4	1705	1711	PF00069	0.614
MOD_Plk_4	1734	1740	PF00069	0.636
MOD_Plk_4	1922	1928	PF00069	0.475
MOD_Plk_4	193	199	PF00069	0.576
MOD_Plk_4	1956	1962	PF00069	0.501
MOD_Plk_4	231	237	PF00069	0.616
MOD_Plk_4	247	253	PF00069	0.408
MOD_Plk_4	30	36	PF00069	0.432
MOD_Plk_4	330	336	PF00069	0.574
MOD_Plk_4	350	356	PF00069	0.525
MOD_Plk_4	359	365	PF00069	0.543
MOD_Plk_4	580	586	PF00069	0.546
MOD_Plk_4	631	637	PF00069	0.546
MOD_Plk_4	685	691	PF00069	0.504
MOD_Plk_4	746	752	PF00069	0.296
MOD_Plk_4	787	793	PF00069	0.546
MOD_ProDKin_1	1011	1017	PF00069	0.669
MOD_ProDKin_1	1060	1066	PF00069	0.497
MOD_ProDKin_1	1106	1112	PF00069	0.389
MOD_ProDKin_1	1234	1240	PF00069	0.635
MOD_ProDKin_1	1243	1249	PF00069	0.649
MOD_ProDKin_1	1318	1324	PF00069	0.429
MOD_ProDKin_1	1471	1477	PF00069	0.531
MOD_ProDKin_1	1504	1510	PF00069	0.640
MOD_ProDKin_1	1518	1524	PF00069	0.672
MOD_ProDKin_1	1567	1573	PF00069	0.684
MOD_ProDKin_1	1639	1645	PF00069	0.566
MOD_ProDKin_1	1674	1680	PF00069	0.647
MOD_ProDKin_1	1696	1702	PF00069	0.489
MOD_ProDKin_1	176	182	PF00069	0.587
MOD_ProDKin_1	1773	1779	PF00069	0.692
MOD_ProDKin_1	1866	1872	PF00069	0.570
MOD_ProDKin_1	1893	1899	PF00069	0.548
MOD_ProDKin_1	1959	1965	PF00069	0.572
MOD_ProDKin_1	1978	1984	PF00069	0.664
MOD_ProDKin_1	219	225	PF00069	0.495
MOD_ProDKin_1	265	271	PF00069	0.633
MOD_ProDKin_1	340	346	PF00069	0.674
MOD_ProDKin_1	357	363	PF00069	0.536
MOD_ProDKin_1	40	46	PF00069	0.447
MOD_ProDKin_1	414	420	PF00069	0.637
MOD_ProDKin_1	445	451	PF00069	0.460
MOD_ProDKin_1	460	466	PF00069	0.445
MOD_ProDKin_1	584	590	PF00069	0.538
MOD_ProDKin_1	636	642	PF00069	0.546
MOD_ProDKin_1	694	700	PF00069	0.546
MOD_ProDKin_1	757	763	PF00069	0.519
MOD_ProDKin_1	87	93	PF00069	0.698
MOD_SUMO_for_1	1073	1076	PF00179	0.374
MOD_SUMO_for_1	275	278	PF00179	0.528
MOD_SUMO_rev_2	1422	1432	PF00179	0.604
MOD_SUMO_rev_2	1869	1879	PF00179	0.752
MOD_SUMO_rev_2	268	277	PF00179	0.528
TRG_DiLeu_BaEn_1	1341	1346	PF01217	0.411
TRG_DiLeu_BaEn_4	1213	1219	PF01217	0.435
TRG_DiLeu_BaLyEn_6	585	590	PF01217	0.546
TRG_DiLeu_BaLyEn_6	871	876	PF01217	0.546
TRG_ENDOCYTIC_2	109	112	PF00928	0.431
TRG_ENDOCYTIC_2	133	136	PF00928	0.515
TRG_ENDOCYTIC_2	1359	1362	PF00928	0.546
TRG_ENDOCYTIC_2	1407	1410	PF00928	0.438
TRG_ENDOCYTIC_2	1412	1415	PF00928	0.465
TRG_ENDOCYTIC_2	1604	1607	PF00928	0.636
TRG_ENDOCYTIC_2	35	38	PF00928	0.419
TRG_ENDOCYTIC_2	598	601	PF00928	0.506
TRG_ENDOCYTIC_2	684	687	PF00928	0.546
TRG_ENDOCYTIC_2	976	979	PF00928	0.524
TRG_ER_diArg_1	1007	1010	PF00400	0.527
TRG_ER_diArg_1	1082	1085	PF00400	0.583
TRG_ER_diArg_1	1261	1264	PF00400	0.636
TRG_ER_diArg_1	1293	1296	PF00400	0.696
TRG_ER_diArg_1	1436	1439	PF00400	0.605
TRG_ER_diArg_1	1541	1544	PF00400	0.666
TRG_ER_diArg_1	1721	1724	PF00400	0.567
TRG_ER_diArg_1	526	528	PF00400	0.493
TRG_ER_diArg_1	783	785	PF00400	0.546
TRG_ER_diArg_1	903	905	PF00400	0.546
TRG_NES_CRM1_1	1878	1891	PF08389	0.558
TRG_NES_CRM1_1	319	331	PF08389	0.493
TRG_NES_CRM1_1	525	538	PF08389	0.465
TRG_NES_CRM1_1	812	828	PF08389	0.546
TRG_NLS_MonoCore_2	1177	1182	PF00514	0.621
TRG_NLS_MonoExtC_3	1177	1182	PF00514	0.637
TRG_NLS_MonoExtC_3	1293	1298	PF00514	0.688
TRG_NLS_MonoExtN_4	1178	1184	PF00514	0.631
TRG_NLS_MonoExtN_4	1292	1299	PF00514	0.688
TRG_Pf-PMV_PEXEL_1	1026	1030	PF00026	0.425
TRG_Pf-PMV_PEXEL_1	1031	1035	PF00026	0.428
TRG_Pf-PMV_PEXEL_1	284	288	PF00026	0.695
TRG_Pf-PMV_PEXEL_1	620	624	PF00026	0.346

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P880	Leptomonas seymouri	49%	100%
A0A3Q8IC54	Leishmania donovani	76%	100%
A4I0Z1	Leishmania infantum	74%	100%
E9AWZ8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	76%	100%
Q4QAH8	Leishmania major	76%	96%