Putative translation factor sui1

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Eukaryotic translation initiation factor 1, putative

Species:

Leishmania braziliensis

UniProt:

A4HDH8_LEIBR

TriTrypDb:

LbrM.24.1230 , LBRM2903_240018400

Length:

107

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 25

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4HDH8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HDH8

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	11
GO:0003743	translation initiation factor activity	4	11
GO:0005488	binding	1	11
GO:0008135	translation factor activity, RNA binding	3	11
GO:0045182	translation regulator activity	1	11
GO:0090079	translation regulator activity, nucleic acid binding	2	11
GO:0097159	organic cyclic compound binding	2	11
GO:1901363	heterocyclic compound binding	2	11
GO:0003723	RNA binding	4	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	69	73	PF00656	0.531
CLV_NRD_NRD_1	31	33	PF00675	0.293
CLV_NRD_NRD_1	59	61	PF00675	0.291
CLV_PCSK_KEX2_1	59	61	PF00082	0.302
CLV_PCSK_PC7_1	55	61	PF00082	0.317
CLV_PCSK_SKI1_1	17	21	PF00082	0.630
CLV_PCSK_SKI1_1	36	40	PF00082	0.297
CLV_PCSK_SKI1_1	88	92	PF00082	0.311
DEG_Nend_UBRbox_2	1	3	PF02207	0.663
DOC_CKS1_1	68	73	PF01111	0.528
DOC_PP1_RVXF_1	45	51	PF00149	0.549
DOC_WW_Pin1_4	67	72	PF00397	0.515
LIG_BRCT_BRCA1_1	53	57	PF00533	0.507
LIG_Pex14_2	57	61	PF04695	0.497
MOD_Cter_Amidation	33	36	PF01082	0.297
MOD_GSK3_1	63	70	PF00069	0.499
MOD_N-GLC_1	63	68	PF02516	0.286
MOD_N-GLC_1	81	86	PF02516	0.297
MOD_NEK2_1	37	42	PF00069	0.502
MOD_NEK2_2	83	88	PF00069	0.420
MOD_PKA_2	12	18	PF00069	0.660
MOD_PKA_2	51	57	PF00069	0.507
MOD_Plk_1	1	7	PF00069	0.641
MOD_Plk_4	63	69	PF00069	0.497
MOD_Plk_4	72	78	PF00069	0.528
MOD_ProDKin_1	67	73	PF00069	0.515
TRG_ER_diArg_1	59	61	PF00400	0.491
TRG_NLS_MonoExtC_3	31	36	PF00514	0.528

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5I4	Leptomonas seymouri	89%	100%
A0A0S4J1Q1	Bodo saltans	65%	100%
A0A1X0NVM9	Trypanosomatidae	71%	98%
A0A3Q8IEW2	Leishmania donovani	96%	100%
A0A422NQ99	Trypanosoma rangeli	79%	98%
A4I0V9	Leishmania infantum	96%	100%
A6MZM2	Oryza sativa subsp. indica	39%	93%
D0A790	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	72%	98%
E9AWW3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	96%	100%
O48650	Salix bakko	41%	95%
O60739	Homo sapiens	42%	95%
O82569	Spuriopimpinella brachycarpa	37%	95%
P32911	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	35%	99%
P41567	Homo sapiens	43%	95%
P41568	Arabidopsis thaliana	41%	95%
P42678	Anopheles gambiae	45%	97%
P48024	Mus musculus	43%	95%
P51971	Gallus gallus	42%	100%
P56330	Zea mays	39%	93%
P61220	Sus scrofa	42%	95%
P79060	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	41%	98%
Q0D5W6	Oryza sativa subsp. japonica	39%	93%
Q4QAL1	Leishmania major	96%	100%
Q4R4X9	Macaca fascicularis	42%	95%
Q5E938	Bos taurus	43%	95%
Q5RFF4	Pongo abelii	43%	95%
Q755R1	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	36%	99%
Q94JV4	Arabidopsis thaliana	41%	95%
Q9CXU9	Mus musculus	42%	95%
Q9SM41	Sporobolus stapfianus	39%	93%
Q9SQF4	Brassica oleracea	40%	95%
Q9VZS3	Drosophila melanogaster	45%	97%