DNA-directed RNA polymerase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DNA-directed RNA polymerase, mitochondrial

Species:

Leishmania braziliensis

UniProt:

A4HDH2_LEIBR

TriTrypDb:

LbrM.24.1170 , LBRM2903_240017800

Length:

1299

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0000428	DNA-directed RNA polymerase complex	4	12
GO:0030880	RNA polymerase complex	3	12
GO:0032991	protein-containing complex	1	12
GO:0061695	transferase complex, transferring phosphorus-containing groups	4	12
GO:0140535	intracellular protein-containing complex	2	12
GO:1902494	catalytic complex	2	12
GO:1990234	transferase complex	3	12
GO:0005737	cytoplasm	2	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0034245	mitochondrial DNA-directed RNA polymerase complex	3	1
GO:0097014	ciliary plasm	5	1
GO:0098798	mitochondrial protein-containing complex	2	1
GO:0099568	cytoplasmic region	3	1
GO:0110165	cellular anatomical entity	1	2
GO:0016020	membrane	2	1

Expansion

Sequence features

A4HDH2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	12
GO:0006351	DNA-templated transcription	7	12
GO:0006725	cellular aromatic compound metabolic process	3	12
GO:0006807	nitrogen compound metabolic process	2	12
GO:0008152	metabolic process	1	12
GO:0009058	biosynthetic process	2	12
GO:0009059	macromolecule biosynthetic process	4	12
GO:0009987	cellular process	1	12
GO:0016070	RNA metabolic process	5	12
GO:0018130	heterocycle biosynthetic process	4	12
GO:0019438	aromatic compound biosynthetic process	4	12
GO:0032774	RNA biosynthetic process	5	12
GO:0034641	cellular nitrogen compound metabolic process	3	12
GO:0034654	nucleobase-containing compound biosynthetic process	4	12
GO:0043170	macromolecule metabolic process	3	12
GO:0044237	cellular metabolic process	2	12
GO:0044238	primary metabolic process	2	12
GO:0044249	cellular biosynthetic process	3	12
GO:0044271	cellular nitrogen compound biosynthetic process	4	12
GO:0046483	heterocycle metabolic process	3	12
GO:0071704	organic substance metabolic process	2	12
GO:0090304	nucleic acid metabolic process	4	12
GO:0097659	nucleic acid-templated transcription	6	12
GO:1901360	organic cyclic compound metabolic process	3	12
GO:1901362	organic cyclic compound biosynthetic process	4	12
GO:1901576	organic substance biosynthetic process	3	12
GO:0000959	mitochondrial RNA metabolic process	6	1
GO:0006259	DNA metabolic process	4	1
GO:0006260	DNA replication	5	1
GO:0006261	DNA-templated DNA replication	6	1
GO:0006264	mitochondrial DNA replication	6	1
GO:0006390	mitochondrial transcription	7	1
GO:0032042	mitochondrial DNA metabolic process	5	1
GO:0044260	obsolete cellular macromolecule metabolic process	3	1

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	12
GO:0003677	DNA binding	4	12
GO:0003824	catalytic activity	1	12
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	6	12
GO:0005488	binding	1	12
GO:0016740	transferase activity	2	12
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	12
GO:0016779	nucleotidyltransferase activity	4	12
GO:0034062	5'-3' RNA polymerase activity	5	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097747	RNA polymerase activity	4	12
GO:0140098	catalytic activity, acting on RNA	3	12
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:1901363	heterocyclic compound binding	2	12
GO:0001064	single subunit type RNA polymerase activity	7	1
GO:0001065	mitochondrial single subunit type RNA polymerase activity	8	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	496	500	PF00656	0.266
CLV_C14_Caspase3-7	776	780	PF00656	0.377
CLV_C14_Caspase3-7	960	964	PF00656	0.314
CLV_NRD_NRD_1	1055	1057	PF00675	0.274
CLV_NRD_NRD_1	1124	1126	PF00675	0.287
CLV_NRD_NRD_1	1186	1188	PF00675	0.283
CLV_NRD_NRD_1	1271	1273	PF00675	0.274
CLV_NRD_NRD_1	205	207	PF00675	0.520
CLV_NRD_NRD_1	258	260	PF00675	0.388
CLV_NRD_NRD_1	268	270	PF00675	0.338
CLV_NRD_NRD_1	375	377	PF00675	0.409
CLV_NRD_NRD_1	592	594	PF00675	0.399
CLV_NRD_NRD_1	789	791	PF00675	0.626
CLV_NRD_NRD_1	815	817	PF00675	0.407
CLV_PCSK_KEX2_1	1055	1057	PF00082	0.283
CLV_PCSK_KEX2_1	1060	1062	PF00082	0.274
CLV_PCSK_KEX2_1	1124	1126	PF00082	0.279
CLV_PCSK_KEX2_1	1271	1273	PF00082	0.274
CLV_PCSK_KEX2_1	1282	1284	PF00082	0.274
CLV_PCSK_KEX2_1	205	207	PF00082	0.369
CLV_PCSK_KEX2_1	258	260	PF00082	0.400
CLV_PCSK_KEX2_1	375	377	PF00082	0.409
CLV_PCSK_KEX2_1	650	652	PF00082	0.477
CLV_PCSK_KEX2_1	788	790	PF00082	0.613
CLV_PCSK_KEX2_1	815	817	PF00082	0.407
CLV_PCSK_PC1ET2_1	1055	1057	PF00082	0.283
CLV_PCSK_PC1ET2_1	1060	1062	PF00082	0.274
CLV_PCSK_PC1ET2_1	1282	1284	PF00082	0.289
CLV_PCSK_PC1ET2_1	650	652	PF00082	0.477
CLV_PCSK_PC7_1	1056	1062	PF00082	0.297
CLV_PCSK_SKI1_1	1022	1026	PF00082	0.356
CLV_PCSK_SKI1_1	1057	1061	PF00082	0.294
CLV_PCSK_SKI1_1	1143	1147	PF00082	0.353
CLV_PCSK_SKI1_1	1188	1192	PF00082	0.329
CLV_PCSK_SKI1_1	172	176	PF00082	0.534
CLV_PCSK_SKI1_1	205	209	PF00082	0.391
CLV_PCSK_SKI1_1	269	273	PF00082	0.446
CLV_PCSK_SKI1_1	328	332	PF00082	0.260
CLV_PCSK_SKI1_1	447	451	PF00082	0.307
CLV_PCSK_SKI1_1	651	655	PF00082	0.396
CLV_PCSK_SKI1_1	746	750	PF00082	0.326
CLV_PCSK_SKI1_1	790	794	PF00082	0.546
CLV_PCSK_SKI1_1	883	887	PF00082	0.425
CLV_PCSK_SKI1_1	997	1001	PF00082	0.277
CLV_Separin_Metazoa	300	304	PF03568	0.449
CLV_Separin_Metazoa	444	448	PF03568	0.376
DEG_APCC_DBOX_1	1186	1194	PF00400	0.274
DEG_APCC_DBOX_1	204	212	PF00400	0.505
DEG_COP1_1	106	114	PF00400	0.563
DEG_Nend_UBRbox_1	1	4	PF02207	0.422
DEG_SCF_FBW7_1	622	629	PF00400	0.357
DOC_CKS1_1	1148	1153	PF01111	0.274
DOC_CKS1_1	1168	1173	PF01111	0.145
DOC_CYCLIN_RxL_1	202	210	PF00134	0.449
DOC_CYCLIN_RxL_1	880	890	PF00134	0.406
DOC_CYCLIN_yCln2_LP_2	105	111	PF00134	0.500
DOC_CYCLIN_yCln2_LP_2	1292	1298	PF00134	0.274
DOC_CYCLIN_yCln2_LP_2	365	371	PF00134	0.230
DOC_MAPK_gen_1	1106	1115	PF00069	0.274
DOC_MAPK_gen_1	1271	1277	PF00069	0.301
DOC_MAPK_gen_1	1282	1290	PF00069	0.238
DOC_MAPK_gen_1	177	186	PF00069	0.525
DOC_MAPK_gen_1	485	492	PF00069	0.420
DOC_MAPK_gen_1	743	751	PF00069	0.311
DOC_MAPK_gen_1	833	843	PF00069	0.378
DOC_MAPK_gen_1	844	852	PF00069	0.243
DOC_MAPK_HePTP_8	1105	1117	PF00069	0.274
DOC_MAPK_HePTP_8	174	186	PF00069	0.403
DOC_MAPK_HePTP_8	627	639	PF00069	0.321
DOC_MAPK_MEF2A_6	1108	1117	PF00069	0.274
DOC_MAPK_MEF2A_6	1282	1290	PF00069	0.275
DOC_MAPK_MEF2A_6	177	186	PF00069	0.473
DOC_MAPK_MEF2A_6	485	492	PF00069	0.500
DOC_MAPK_MEF2A_6	630	639	PF00069	0.284
DOC_MAPK_MEF2A_6	973	982	PF00069	0.436
DOC_MAPK_NFAT4_5	1283	1291	PF00069	0.274
DOC_MAPK_NFAT4_5	485	493	PF00069	0.423
DOC_MIT_MIM_1	355	365	PF04212	0.396
DOC_PP1_RVXF_1	487	493	PF00149	0.433
DOC_PP1_RVXF_1	628	635	PF00149	0.321
DOC_PP1_RVXF_1	912	918	PF00149	0.303
DOC_PP2B_LxvP_1	595	598	PF13499	0.413
DOC_PP4_FxxP_1	109	112	PF00568	0.556
DOC_PP4_FxxP_1	82	85	PF00568	0.652
DOC_USP7_MATH_1	1178	1182	PF00917	0.378
DOC_USP7_MATH_1	129	133	PF00917	0.491
DOC_USP7_MATH_1	238	242	PF00917	0.491
DOC_USP7_MATH_1	313	317	PF00917	0.196
DOC_USP7_MATH_1	383	387	PF00917	0.498
DOC_USP7_MATH_1	52	56	PF00917	0.424
DOC_USP7_MATH_1	675	679	PF00917	0.403
DOC_USP7_MATH_1	965	969	PF00917	0.193
DOC_USP7_UBL2_3	1022	1026	PF12436	0.368
DOC_USP7_UBL2_3	1051	1055	PF12436	0.437
DOC_WW_Pin1_4	1147	1152	PF00397	0.274
DOC_WW_Pin1_4	1167	1172	PF00397	0.145
DOC_WW_Pin1_4	1291	1296	PF00397	0.274
DOC_WW_Pin1_4	309	314	PF00397	0.346
DOC_WW_Pin1_4	622	627	PF00397	0.335
DOC_WW_Pin1_4	92	97	PF00397	0.565
LIG_14-3-3_CanoR_1	1061	1070	PF00244	0.287
LIG_14-3-3_CanoR_1	1124	1134	PF00244	0.274
LIG_14-3-3_CanoR_1	1187	1197	PF00244	0.274
LIG_14-3-3_CanoR_1	172	180	PF00244	0.447
LIG_14-3-3_CanoR_1	426	432	PF00244	0.263
LIG_14-3-3_CanoR_1	543	547	PF00244	0.447
LIG_14-3-3_CanoR_1	593	598	PF00244	0.462
LIG_14-3-3_CanoR_1	610	616	PF00244	0.440
LIG_14-3-3_CanoR_1	656	661	PF00244	0.394
LIG_14-3-3_CanoR_1	75	80	PF00244	0.512
LIG_14-3-3_CanoR_1	815	821	PF00244	0.310
LIG_Actin_WH2_2	1127	1145	PF00022	0.289
LIG_Actin_WH2_2	209	224	PF00022	0.435
LIG_AP2alpha_2	107	109	PF02296	0.567
LIG_AP2alpha_2	880	882	PF02296	0.408
LIG_APCC_ABBAyCdc20_2	543	549	PF00400	0.515
LIG_BIR_III_4	193	197	PF00653	0.504
LIG_BIR_III_4	998	1002	PF00653	0.274
LIG_BRCT_BRCA1_1	105	109	PF00533	0.505
LIG_BRCT_BRCA1_1	1293	1297	PF00533	0.274
LIG_BRCT_BRCA1_1	28	32	PF00533	0.618
LIG_BRCT_BRCA1_1	859	863	PF00533	0.318
LIG_BRCT_BRCA1_1	878	882	PF00533	0.404
LIG_Clathr_ClatBox_1	41	45	PF01394	0.537
LIG_deltaCOP1_diTrp_1	1253	1262	PF00928	0.274
LIG_EH1_1	633	641	PF00400	0.282
LIG_EVH1_1	1277	1281	PF00568	0.274
LIG_FHA_1	1016	1022	PF00498	0.288
LIG_FHA_1	1147	1153	PF00498	0.293
LIG_FHA_1	169	175	PF00498	0.382
LIG_FHA_1	202	208	PF00498	0.399
LIG_FHA_1	216	222	PF00498	0.455
LIG_FHA_1	250	256	PF00498	0.383
LIG_FHA_1	471	477	PF00498	0.301
LIG_FHA_1	577	583	PF00498	0.363
LIG_FHA_1	627	633	PF00498	0.309
LIG_FHA_2	1092	1098	PF00498	0.274
LIG_FHA_2	1114	1120	PF00498	0.307
LIG_FHA_2	1207	1213	PF00498	0.274
LIG_FHA_2	15	21	PF00498	0.636
LIG_FHA_2	347	353	PF00498	0.380
LIG_FHA_2	543	549	PF00498	0.290
LIG_FHA_2	662	668	PF00498	0.361
LIG_FHA_2	875	881	PF00498	0.412
LIG_GBD_Chelix_1	297	305	PF00786	0.225
LIG_Integrin_RGD_1	1283	1285	PF01839	0.274
LIG_Integrin_RGD_1	645	647	PF01839	0.437
LIG_LIR_Apic_2	106	112	PF02991	0.501
LIG_LIR_Apic_2	80	85	PF02991	0.650
LIG_LIR_Apic_2	887	891	PF02991	0.374
LIG_LIR_Gen_1	1243	1252	PF02991	0.368
LIG_LIR_Gen_1	1264	1275	PF02991	0.334
LIG_LIR_Gen_1	244	249	PF02991	0.404
LIG_LIR_Gen_1	29	39	PF02991	0.454
LIG_LIR_Gen_1	430	439	PF02991	0.337
LIG_LIR_Gen_1	655	663	PF02991	0.396
LIG_LIR_Nem_3	1015	1020	PF02991	0.300
LIG_LIR_Nem_3	1225	1230	PF02991	0.277
LIG_LIR_Nem_3	1243	1248	PF02991	0.288
LIG_LIR_Nem_3	1250	1255	PF02991	0.257
LIG_LIR_Nem_3	1264	1270	PF02991	0.264
LIG_LIR_Nem_3	132	136	PF02991	0.484
LIG_LIR_Nem_3	244	248	PF02991	0.404
LIG_LIR_Nem_3	29	35	PF02991	0.514
LIG_LIR_Nem_3	312	317	PF02991	0.302
LIG_LIR_Nem_3	320	324	PF02991	0.264
LIG_LIR_Nem_3	430	434	PF02991	0.474
LIG_LIR_Nem_3	523	528	PF02991	0.361
LIG_LIR_Nem_3	655	660	PF02991	0.412
LIG_LIR_Nem_3	705	710	PF02991	0.389
LIG_LIR_Nem_3	825	829	PF02991	0.307
LIG_LIR_Nem_3	879	885	PF02991	0.418
LIG_LIR_Nem_3	983	989	PF02991	0.274
LIG_MLH1_MIPbox_1	1293	1297	PF16413	0.274
LIG_NRBOX	361	367	PF00104	0.349
LIG_NRBOX	570	576	PF00104	0.444
LIG_PCNA_PIPBox_1	1	10	PF02747	0.442
LIG_PCNA_PIPBox_1	1098	1107	PF02747	0.274
LIG_Pex14_1	1262	1266	PF04695	0.274
LIG_Pex14_2	584	588	PF04695	0.290
LIG_PTB_Apo_2	1290	1297	PF02174	0.368
LIG_PTB_Phospho_1	1290	1296	PF10480	0.368
LIG_SH2_CRK	1017	1021	PF00017	0.274
LIG_SH2_CRK	1174	1178	PF00017	0.368
LIG_SH2_CRK	133	137	PF00017	0.512
LIG_SH2_CRK	294	298	PF00017	0.395
LIG_SH2_CRK	324	328	PF00017	0.215
LIG_SH2_CRK	592	596	PF00017	0.390
LIG_SH2_CRK	707	711	PF00017	0.381
LIG_SH2_CRK	986	990	PF00017	0.274
LIG_SH2_CRK	992	996	PF00017	0.274
LIG_SH2_NCK_1	1174	1178	PF00017	0.368
LIG_SH2_NCK_1	133	137	PF00017	0.512
LIG_SH2_NCK_1	992	996	PF00017	0.274
LIG_SH2_SRC	888	891	PF00017	0.364
LIG_SH2_STAP1	1230	1234	PF00017	0.274
LIG_SH2_STAT3	461	464	PF00017	0.378
LIG_SH2_STAT5	1017	1020	PF00017	0.310
LIG_SH2_STAT5	1104	1107	PF00017	0.314
LIG_SH2_STAT5	1266	1269	PF00017	0.289
LIG_SH2_STAT5	1296	1299	PF00017	0.274
LIG_SH2_STAT5	317	320	PF00017	0.300
LIG_SH2_STAT5	321	324	PF00017	0.272
LIG_SH2_STAT5	461	464	PF00017	0.377
LIG_SH2_STAT5	508	511	PF00017	0.371
LIG_SH2_STAT5	617	620	PF00017	0.395
LIG_SH2_STAT5	641	644	PF00017	0.382
LIG_SH2_STAT5	839	842	PF00017	0.313
LIG_SH2_STAT5	856	859	PF00017	0.313
LIG_SH2_STAT5	923	926	PF00017	0.274
LIG_SH3_2	1278	1283	PF14604	0.274
LIG_SH3_3	1153	1159	PF00018	0.288
LIG_SH3_3	1272	1278	PF00018	0.283
LIG_SH3_3	307	313	PF00018	0.236
LIG_SH3_3	342	348	PF00018	0.363
LIG_SH3_3	681	687	PF00018	0.368
LIG_SUMO_SIM_anti_2	148	156	PF11976	0.428
LIG_SUMO_SIM_anti_2	548	555	PF11976	0.470
LIG_SUMO_SIM_par_1	978	983	PF11976	0.328
LIG_TRAF2_1	349	352	PF00917	0.417
LIG_TRAF2_1	539	542	PF00917	0.501
LIG_TYR_ITIM	322	327	PF00017	0.210
LIG_UBA3_1	1020	1026	PF00899	0.334
LIG_UBA3_1	1079	1088	PF00899	0.274
LIG_UBA3_1	571	577	PF00899	0.315
LIG_WRC_WIRS_1	165	170	PF05994	0.367
LIG_WRC_WIRS_1	641	646	PF05994	0.366
MOD_CK1_1	103	109	PF00069	0.582
MOD_CK1_1	1167	1173	PF00069	0.376
MOD_CK1_1	1226	1232	PF00069	0.285
MOD_CK1_1	134	140	PF00069	0.431
MOD_CK1_1	173	179	PF00069	0.478
MOD_CK1_1	241	247	PF00069	0.497
MOD_CK1_1	251	257	PF00069	0.460
MOD_CK1_1	405	411	PF00069	0.474
MOD_CK1_1	470	476	PF00069	0.297
MOD_CK1_1	691	697	PF00069	0.377
MOD_CK1_1	77	83	PF00069	0.551
MOD_CK1_1	913	919	PF00069	0.292
MOD_CK2_1	1113	1119	PF00069	0.274
MOD_CK2_1	1206	1212	PF00069	0.274
MOD_CK2_1	14	20	PF00069	0.602
MOD_CK2_1	34	40	PF00069	0.481
MOD_CK2_1	346	352	PF00069	0.420
MOD_CK2_1	542	548	PF00069	0.565
MOD_CK2_1	913	919	PF00069	0.283
MOD_GlcNHglycan	127	130	PF01048	0.513
MOD_GlcNHglycan	133	136	PF01048	0.466
MOD_GlcNHglycan	147	150	PF01048	0.361
MOD_GlcNHglycan	218	221	PF01048	0.382
MOD_GlcNHglycan	354	358	PF01048	0.377
MOD_GlcNHglycan	36	39	PF01048	0.388
MOD_GlcNHglycan	454	457	PF01048	0.337
MOD_GlcNHglycan	499	502	PF01048	0.480
MOD_GlcNHglycan	567	570	PF01048	0.376
MOD_GlcNHglycan	595	598	PF01048	0.371
MOD_GlcNHglycan	79	82	PF01048	0.620
MOD_GlcNHglycan	790	793	PF01048	0.565
MOD_GlcNHglycan	90	93	PF01048	0.606
MOD_GlcNHglycan	933	936	PF01048	0.274
MOD_GlcNHglycan	939	942	PF01048	0.274
MOD_GlcNHglycan	992	995	PF01048	0.274
MOD_GSK3_1	1069	1076	PF00069	0.345
MOD_GSK3_1	1109	1116	PF00069	0.274
MOD_GSK3_1	1197	1204	PF00069	0.290
MOD_GSK3_1	125	132	PF00069	0.484
MOD_GSK3_1	160	167	PF00069	0.371
MOD_GSK3_1	168	175	PF00069	0.410
MOD_GSK3_1	216	223	PF00069	0.281
MOD_GSK3_1	309	316	PF00069	0.208
MOD_GSK3_1	407	414	PF00069	0.475
MOD_GSK3_1	467	474	PF00069	0.381
MOD_GSK3_1	52	59	PF00069	0.606
MOD_GSK3_1	605	612	PF00069	0.418
MOD_GSK3_1	622	629	PF00069	0.217
MOD_GSK3_1	698	705	PF00069	0.366
MOD_GSK3_1	70	77	PF00069	0.519
MOD_GSK3_1	88	95	PF00069	0.528
MOD_LATS_1	1053	1059	PF00433	0.274
MOD_LATS_1	409	415	PF00433	0.502
MOD_N-GLC_1	1086	1091	PF02516	0.417
MOD_N-GLC_1	14	19	PF02516	0.537
MOD_N-GLC_1	226	231	PF02516	0.378
MOD_N-GLC_1	249	254	PF02516	0.465
MOD_N-GLC_1	563	568	PF02516	0.368
MOD_N-GLC_1	605	610	PF02516	0.461
MOD_N-GLC_1	696	701	PF02516	0.520
MOD_N-GLC_1	874	879	PF02516	0.440
MOD_N-GLC_1	92	97	PF02516	0.637
MOD_N-GLC_2	1164	1166	PF02516	0.417
MOD_NEK2_1	1024	1029	PF00069	0.298
MOD_NEK2_1	1113	1118	PF00069	0.274
MOD_NEK2_1	1146	1151	PF00069	0.274
MOD_NEK2_1	1201	1206	PF00069	0.305
MOD_NEK2_1	168	173	PF00069	0.372
MOD_NEK2_1	201	206	PF00069	0.395
MOD_NEK2_1	248	253	PF00069	0.500
MOD_NEK2_1	640	645	PF00069	0.288
MOD_NEK2_1	674	679	PF00069	0.364
MOD_NEK2_1	723	728	PF00069	0.359
MOD_NEK2_1	832	837	PF00069	0.408
MOD_NEK2_1	874	879	PF00069	0.401
MOD_NEK2_1	910	915	PF00069	0.319
MOD_NEK2_2	675	680	PF00069	0.405
MOD_PIKK_1	1062	1068	PF00454	0.295
MOD_PIKK_1	1117	1123	PF00454	0.274
MOD_PIKK_1	1235	1241	PF00454	0.417
MOD_PIKK_1	527	533	PF00454	0.334
MOD_PIKK_1	609	615	PF00454	0.436
MOD_PIKK_1	723	729	PF00454	0.357
MOD_PIKK_1	965	971	PF00454	0.274
MOD_PK_1	170	176	PF00069	0.403
MOD_PK_1	656	662	PF00069	0.360
MOD_PK_1	702	708	PF00069	0.385
MOD_PKA_1	1055	1061	PF00069	0.274
MOD_PKA_1	269	275	PF00069	0.475
MOD_PKA_1	593	599	PF00069	0.367
MOD_PKA_1	788	794	PF00069	0.609
MOD_PKA_2	1055	1061	PF00069	0.274
MOD_PKA_2	1117	1123	PF00069	0.274
MOD_PKA_2	201	207	PF00069	0.304
MOD_PKA_2	216	222	PF00069	0.362
MOD_PKA_2	542	548	PF00069	0.448
MOD_PKA_2	599	605	PF00069	0.382
MOD_PKA_2	609	615	PF00069	0.329
MOD_PKA_2	74	80	PF00069	0.514
MOD_PKA_2	788	794	PF00069	0.609
MOD_PKA_2	832	838	PF00069	0.424
MOD_PKB_1	170	178	PF00069	0.426
MOD_Plk_1	1164	1170	PF00069	0.334
MOD_Plk_1	1201	1207	PF00069	0.274
MOD_Plk_1	1262	1268	PF00069	0.368
MOD_Plk_1	14	20	PF00069	0.655
MOD_Plk_1	226	232	PF00069	0.378
MOD_Plk_1	26	32	PF00069	0.621
MOD_Plk_1	262	268	PF00069	0.433
MOD_Plk_1	353	359	PF00069	0.361
MOD_Plk_1	383	389	PF00069	0.277
MOD_Plk_1	541	547	PF00069	0.451
MOD_Plk_1	702	708	PF00069	0.370
MOD_Plk_2-3	542	548	PF00069	0.300
MOD_Plk_4	100	106	PF00069	0.599
MOD_Plk_4	1164	1170	PF00069	0.368
MOD_Plk_4	1216	1222	PF00069	0.274
MOD_Plk_4	1223	1229	PF00069	0.274
MOD_Plk_4	1262	1268	PF00069	0.353
MOD_Plk_4	160	166	PF00069	0.505
MOD_Plk_4	251	257	PF00069	0.274
MOD_Plk_4	313	319	PF00069	0.279
MOD_Plk_4	471	477	PF00069	0.514
MOD_Plk_4	504	510	PF00069	0.447
MOD_Plk_4	691	697	PF00069	0.377
MOD_Plk_4	702	708	PF00069	0.370
MOD_ProDKin_1	1147	1153	PF00069	0.274
MOD_ProDKin_1	1167	1173	PF00069	0.145
MOD_ProDKin_1	1291	1297	PF00069	0.274
MOD_ProDKin_1	309	315	PF00069	0.345
MOD_ProDKin_1	622	628	PF00069	0.332
MOD_ProDKin_1	92	98	PF00069	0.564
MOD_SUMO_for_1	9	12	PF00179	0.601
MOD_SUMO_rev_2	776	785	PF00179	0.285
MOD_SUMO_rev_2	887	894	PF00179	0.348
TRG_DiLeu_BaEn_1	1129	1134	PF01217	0.368
TRG_DiLeu_BaEn_2	1262	1268	PF01217	0.274
TRG_DiLeu_BaEn_4	541	547	PF01217	0.536
TRG_DiLeu_BaLyEn_6	182	187	PF01217	0.471
TRG_DiLeu_BaLyEn_6	203	208	PF01217	0.450
TRG_ENDOCYTIC_2	1017	1020	PF00928	0.311
TRG_ENDOCYTIC_2	1174	1177	PF00928	0.368
TRG_ENDOCYTIC_2	1252	1255	PF00928	0.274
TRG_ENDOCYTIC_2	133	136	PF00928	0.484
TRG_ENDOCYTIC_2	294	297	PF00928	0.360
TRG_ENDOCYTIC_2	324	327	PF00928	0.337
TRG_ENDOCYTIC_2	479	482	PF00928	0.388
TRG_ENDOCYTIC_2	592	595	PF00928	0.501
TRG_ENDOCYTIC_2	641	644	PF00928	0.432
TRG_ENDOCYTIC_2	707	710	PF00928	0.395
TRG_ENDOCYTIC_2	774	777	PF00928	0.421
TRG_ENDOCYTIC_2	986	989	PF00928	0.274
TRG_ENDOCYTIC_2	992	995	PF00928	0.274
TRG_ER_diArg_1	1124	1126	PF00400	0.217
TRG_ER_diArg_1	1270	1272	PF00400	0.274
TRG_ER_diArg_1	205	207	PF00400	0.512
TRG_ER_diArg_1	257	259	PF00400	0.398
TRG_ER_diArg_1	788	790	PF00400	0.612
TRG_ER_diArg_1	863	866	PF00400	0.354
TRG_NES_CRM1_1	140	156	PF08389	0.476
TRG_NES_CRM1_1	40	53	PF08389	0.343
TRG_NES_CRM1_1	451	464	PF08389	0.340
TRG_Pf-PMV_PEXEL_1	1125	1129	PF00026	0.195
TRG_Pf-PMV_PEXEL_1	185	189	PF00026	0.329
TRG_Pf-PMV_PEXEL_1	205	210	PF00026	0.361
TRG_Pf-PMV_PEXEL_1	827	831	PF00026	0.348
TRG_Pf-PMV_PEXEL_1	847	851	PF00026	0.297
TRG_Pf-PMV_PEXEL_1	883	887	PF00026	0.425
TRG_Pf-PMV_PEXEL_1	892	896	PF00026	0.274

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PCV7	Leptomonas seymouri	73%	83%
A0A0S4J6R7	Bodo saltans	62%	100%
A0A1X0NVL5	Trypanosomatidae	67%	96%
A0A3R7KH63	Trypanosoma rangeli	68%	100%
A0A3S7WYB1	Leishmania donovani	90%	86%
A4I0V3	Leishmania infantum	90%	86%
D0A783	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	63%	99%
E9AWV7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	86%
Q4QAL7	Leishmania major	91%	100%
V5BAK4	Trypanosoma cruzi	68%	100%