Putative pre-mRNA splicing factor

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

pre-mRNA-splicing factor ATP-dependent RNA helicase, putative

Species:

Leishmania braziliensis

UniProt:

A4HDG6_LEIBR

TriTrypDb:

LbrM.24.1110 , LBRM2903_240017000

Length:

1088

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005681	spliceosomal complex	3	1
GO:0032991	protein-containing complex	1	1
GO:0140513	nuclear protein-containing complex	2	1
GO:1990904	ribonucleoprotein complex	2	1

Expansion

Sequence features

A4HDG6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HDG6

Function

Biological processes
Term	Name	Level	Count
GO:0000375	RNA splicing, via transesterification reactions	8	1
GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	9	1
GO:0000398	mRNA splicing, via spliceosome	8	1
GO:0006139	nucleobase-containing compound metabolic process	3	1
GO:0006396	RNA processing	6	1
GO:0006397	mRNA processing	7	1
GO:0006725	cellular aromatic compound metabolic process	3	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0008152	metabolic process	1	1
GO:0008380	RNA splicing	7	1
GO:0009987	cellular process	1	1
GO:0016070	RNA metabolic process	5	1
GO:0016071	mRNA metabolic process	6	1
GO:0034641	cellular nitrogen compound metabolic process	3	1
GO:0043170	macromolecule metabolic process	3	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0046483	heterocycle metabolic process	3	1
GO:0071704	organic substance metabolic process	2	1
GO:0090304	nucleic acid metabolic process	4	1
GO:1901360	organic cyclic compound metabolic process	3	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	11
GO:0003824	catalytic activity	1	12
GO:0004386	helicase activity	2	12
GO:0005488	binding	1	11
GO:0005524	ATP binding	5	11
GO:0016787	hydrolase activity	2	11
GO:0017076	purine nucleotide binding	4	11
GO:0030554	adenyl nucleotide binding	5	11
GO:0032553	ribonucleotide binding	3	11
GO:0032555	purine ribonucleotide binding	4	11
GO:0032559	adenyl ribonucleotide binding	5	11
GO:0035639	purine ribonucleoside triphosphate binding	4	11
GO:0036094	small molecule binding	2	11
GO:0043167	ion binding	2	11
GO:0043168	anion binding	3	11
GO:0097159	organic cyclic compound binding	2	11
GO:0097367	carbohydrate derivative binding	2	11
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:0140657	ATP-dependent activity	1	12
GO:1901265	nucleoside phosphate binding	3	11
GO:1901363	heterocyclic compound binding	2	11
GO:0003676	nucleic acid binding	3	6
GO:0003723	RNA binding	4	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	156	160	PF00656	0.732
CLV_C14_Caspase3-7	742	746	PF00656	0.403
CLV_C14_Caspase3-7	763	767	PF00656	0.506
CLV_MEL_PAP_1	439	445	PF00089	0.396
CLV_NRD_NRD_1	1084	1086	PF00675	0.584
CLV_NRD_NRD_1	118	120	PF00675	0.630
CLV_NRD_NRD_1	145	147	PF00675	0.700
CLV_NRD_NRD_1	336	338	PF00675	0.536
CLV_NRD_NRD_1	349	351	PF00675	0.379
CLV_NRD_NRD_1	366	368	PF00675	0.474
CLV_NRD_NRD_1	371	373	PF00675	0.474
CLV_NRD_NRD_1	432	434	PF00675	0.428
CLV_NRD_NRD_1	441	443	PF00675	0.384
CLV_NRD_NRD_1	520	522	PF00675	0.384
CLV_NRD_NRD_1	535	537	PF00675	0.390
CLV_NRD_NRD_1	611	613	PF00675	0.234
CLV_NRD_NRD_1	651	653	PF00675	0.240
CLV_NRD_NRD_1	706	708	PF00675	0.241
CLV_NRD_NRD_1	907	909	PF00675	0.499
CLV_NRD_NRD_1	943	945	PF00675	0.292
CLV_NRD_NRD_1	969	971	PF00675	0.165
CLV_PCSK_KEX2_1	1083	1085	PF00082	0.616
CLV_PCSK_KEX2_1	11	13	PF00082	0.686
CLV_PCSK_KEX2_1	336	338	PF00082	0.533
CLV_PCSK_KEX2_1	366	368	PF00082	0.452
CLV_PCSK_KEX2_1	371	373	PF00082	0.462
CLV_PCSK_KEX2_1	432	434	PF00082	0.442
CLV_PCSK_KEX2_1	441	443	PF00082	0.384
CLV_PCSK_KEX2_1	519	521	PF00082	0.377
CLV_PCSK_KEX2_1	610	612	PF00082	0.244
CLV_PCSK_KEX2_1	706	708	PF00082	0.308
CLV_PCSK_KEX2_1	943	945	PF00082	0.292
CLV_PCSK_KEX2_1	969	971	PF00082	0.165
CLV_PCSK_PC1ET2_1	1083	1085	PF00082	0.653
CLV_PCSK_PC1ET2_1	11	13	PF00082	0.772
CLV_PCSK_PC7_1	367	373	PF00082	0.556
CLV_PCSK_SKI1_1	1074	1078	PF00082	0.686
CLV_PCSK_SKI1_1	205	209	PF00082	0.557
CLV_PCSK_SKI1_1	242	246	PF00082	0.606
CLV_PCSK_SKI1_1	287	291	PF00082	0.466
CLV_PCSK_SKI1_1	472	476	PF00082	0.341
CLV_PCSK_SKI1_1	515	519	PF00082	0.472
CLV_PCSK_SKI1_1	611	615	PF00082	0.262
CLV_PCSK_SKI1_1	797	801	PF00082	0.192
CLV_PCSK_SKI1_1	8	12	PF00082	0.740
CLV_PCSK_SKI1_1	810	814	PF00082	0.291
CLV_PCSK_SKI1_1	836	840	PF00082	0.240
CLV_PCSK_SKI1_1	949	953	PF00082	0.252
CLV_Separin_Metazoa	385	389	PF03568	0.371
DEG_APCC_DBOX_1	293	301	PF00400	0.458
DEG_APCC_DBOX_1	520	528	PF00400	0.348
DEG_APCC_DBOX_1	609	617	PF00400	0.458
DEG_APCC_DBOX_1	809	817	PF00400	0.531
DEG_Nend_UBRbox_2	1	3	PF02207	0.711
DEG_SCF_FBW7_1	1032	1037	PF00400	0.493
DEG_SPOP_SBC_1	19	23	PF00917	0.510
DOC_ANK_TNKS_1	432	439	PF00023	0.404
DOC_CDC14_PxL_1	887	895	PF14671	0.378
DOC_CKS1_1	1079	1084	PF01111	0.679
DOC_CYCLIN_RxL_1	807	815	PF00134	0.501
DOC_CYCLIN_yCln2_LP_2	800	806	PF00134	0.440
DOC_MAPK_gen_1	117	125	PF00069	0.604
DOC_MAPK_gen_1	371	379	PF00069	0.439
DOC_MAPK_gen_1	432	439	PF00069	0.404
DOC_MAPK_gen_1	519	528	PF00069	0.351
DOC_MAPK_gen_1	906	914	PF00069	0.423
DOC_MAPK_HePTP_8	516	528	PF00069	0.465
DOC_MAPK_MEF2A_6	117	125	PF00069	0.604
DOC_MAPK_MEF2A_6	179	187	PF00069	0.565
DOC_MAPK_MEF2A_6	519	528	PF00069	0.351
DOC_MAPK_MEF2A_6	576	584	PF00069	0.360
DOC_MAPK_MEF2A_6	589	596	PF00069	0.452
DOC_MAPK_MEF2A_6	906	914	PF00069	0.431
DOC_MAPK_MEF2A_6	949	956	PF00069	0.365
DOC_MAPK_NFAT4_5	521	529	PF00069	0.353
DOC_PP1_RVXF_1	468	474	PF00149	0.475
DOC_PP2B_LxvP_1	1051	1054	PF13499	0.718
DOC_PP2B_LxvP_1	582	585	PF13499	0.504
DOC_PP2B_LxvP_1	625	628	PF13499	0.379
DOC_PP2B_LxvP_1	888	891	PF13499	0.383
DOC_PP4_FxxP_1	839	842	PF00568	0.440
DOC_PP4_MxPP_1	127	130	PF00568	0.298
DOC_USP7_MATH_1	1034	1038	PF00917	0.640
DOC_USP7_MATH_1	1043	1047	PF00917	0.673
DOC_USP7_MATH_1	1054	1058	PF00917	0.702
DOC_USP7_MATH_1	1068	1072	PF00917	0.601
DOC_USP7_MATH_1	188	192	PF00917	0.526
DOC_USP7_MATH_1	66	70	PF00917	0.576
DOC_USP7_MATH_1	661	665	PF00917	0.449
DOC_USP7_MATH_1	73	77	PF00917	0.554
DOC_USP7_MATH_1	913	917	PF00917	0.441
DOC_USP7_MATH_1	938	942	PF00917	0.452
DOC_USP7_UBL2_3	1069	1073	PF12436	0.684
DOC_USP7_UBL2_3	843	847	PF12436	0.526
DOC_WW_Pin1_4	1030	1035	PF00397	0.758
DOC_WW_Pin1_4	1039	1044	PF00397	0.658
DOC_WW_Pin1_4	1046	1051	PF00397	0.573
DOC_WW_Pin1_4	1078	1083	PF00397	0.678
DOC_WW_Pin1_4	20	25	PF00397	0.736
DOC_WW_Pin1_4	559	564	PF00397	0.468
DOC_WW_Pin1_4	614	619	PF00397	0.526
DOC_WW_Pin1_4	644	649	PF00397	0.481
DOC_WW_Pin1_4	802	807	PF00397	0.529
LIG_14-3-3_CanoR_1	1011	1020	PF00244	0.577
LIG_14-3-3_CanoR_1	1061	1065	PF00244	0.645
LIG_14-3-3_CanoR_1	179	187	PF00244	0.644
LIG_14-3-3_CanoR_1	205	214	PF00244	0.327
LIG_14-3-3_CanoR_1	610	618	PF00244	0.482
LIG_14-3-3_CanoR_1	709	719	PF00244	0.510
LIG_14-3-3_CanoR_1	720	727	PF00244	0.384
LIG_14-3-3_CanoR_1	741	745	PF00244	0.421
LIG_14-3-3_CanoR_1	774	778	PF00244	0.381
LIG_14-3-3_CanoR_1	826	831	PF00244	0.373
LIG_14-3-3_CanoR_1	943	952	PF00244	0.465
LIG_Actin_WH2_2	467	483	PF00022	0.358
LIG_Actin_WH2_2	502	517	PF00022	0.361
LIG_BIR_III_2	2	6	PF00653	0.686
LIG_BIR_III_2	645	649	PF00653	0.515
LIG_BIR_III_2	766	770	PF00653	0.512
LIG_BRCT_BRCA1_1	538	542	PF00533	0.342
LIG_eIF4E_1	603	609	PF01652	0.501
LIG_EVH1_2	129	133	PF00568	0.553
LIG_FHA_1	153	159	PF00498	0.570
LIG_FHA_1	301	307	PF00498	0.496
LIG_FHA_1	405	411	PF00498	0.323
LIG_FHA_1	473	479	PF00498	0.344
LIG_FHA_1	505	511	PF00498	0.335
LIG_FHA_1	530	536	PF00498	0.392
LIG_FHA_1	552	558	PF00498	0.420
LIG_FHA_1	57	63	PF00498	0.775
LIG_FHA_1	603	609	PF00498	0.481
LIG_FHA_1	621	627	PF00498	0.452
LIG_FHA_1	787	793	PF00498	0.461
LIG_FHA_1	869	875	PF00498	0.363
LIG_FHA_1	955	961	PF00498	0.401
LIG_FHA_2	111	117	PF00498	0.452
LIG_FHA_2	149	155	PF00498	0.478
LIG_FHA_2	206	212	PF00498	0.549
LIG_FHA_2	343	349	PF00498	0.623
LIG_FHA_2	358	364	PF00498	0.525
LIG_FHA_2	42	48	PF00498	0.561
LIG_FHA_2	463	469	PF00498	0.434
LIG_FHA_2	481	487	PF00498	0.309
LIG_FHA_2	62	68	PF00498	0.642
LIG_FHA_2	982	988	PF00498	0.447
LIG_FHA_2	991	997	PF00498	0.440
LIG_Integrin_RGD_1	521	523	PF01839	0.495
LIG_Integrin_RGD_TGFB_3	521	527	PF01839	0.463
LIG_LIR_Apic_2	142	148	PF02991	0.449
LIG_LIR_Gen_1	490	500	PF02991	0.368
LIG_LIR_Gen_1	761	770	PF02991	0.384
LIG_LIR_Gen_1	987	995	PF02991	0.445
LIG_LIR_Nem_3	238	243	PF02991	0.631
LIG_LIR_Nem_3	490	495	PF02991	0.376
LIG_LIR_Nem_3	717	722	PF02991	0.473
LIG_LIR_Nem_3	942	948	PF02991	0.439
LIG_MLH1_MIPbox_1	538	542	PF16413	0.342
LIG_NRBOX	230	236	PF00104	0.566
LIG_NRBOX	620	626	PF00104	0.452
LIG_NRBOX	807	813	PF00104	0.526
LIG_PCNA_PIPBox_1	36	45	PF02747	0.423
LIG_PCNA_yPIPBox_3	29	43	PF02747	0.535
LIG_Pex14_1	781	785	PF04695	0.531
LIG_Pex14_2	538	542	PF04695	0.342
LIG_PTB_Apo_2	772	779	PF02174	0.242
LIG_SH2_CRK	240	244	PF00017	0.564
LIG_SH2_CRK	492	496	PF00017	0.340
LIG_SH2_CRK	948	952	PF00017	0.462
LIG_SH2_GRB2like	857	860	PF00017	0.448
LIG_SH2_NCK_1	548	552	PF00017	0.380
LIG_SH2_SRC	548	551	PF00017	0.367
LIG_SH2_SRC	873	876	PF00017	0.455
LIG_SH2_STAP1	457	461	PF00017	0.373
LIG_SH2_STAP1	492	496	PF00017	0.340
LIG_SH2_STAP1	727	731	PF00017	0.518
LIG_SH2_STAT3	413	416	PF00017	0.428
LIG_SH2_STAT5	288	291	PF00017	0.550
LIG_SH2_STAT5	389	392	PF00017	0.465
LIG_SH2_STAT5	413	416	PF00017	0.371
LIG_SH2_STAT5	569	572	PF00017	0.347
LIG_SH2_STAT5	672	675	PF00017	0.440
LIG_SH2_STAT5	722	725	PF00017	0.384
LIG_SH2_STAT5	79	82	PF00017	0.623
LIG_SH2_STAT5	873	876	PF00017	0.462
LIG_SH2_STAT5	927	930	PF00017	0.484
LIG_SH2_STAT5	975	978	PF00017	0.470
LIG_SH2_STAT5	988	991	PF00017	0.440
LIG_SH3_3	182	188	PF00018	0.390
LIG_SH3_3	254	260	PF00018	0.490
LIG_SH3_3	481	487	PF00018	0.380
LIG_SH3_3	680	686	PF00018	0.440
LIG_SH3_3	800	806	PF00018	0.440
LIG_SH3_3	907	913	PF00018	0.439
LIG_SH3_5	565	569	PF00018	0.383
LIG_SUMO_SIM_anti_2	1013	1025	PF11976	0.458
LIG_SUMO_SIM_anti_2	181	187	PF11976	0.637
LIG_SUMO_SIM_anti_2	392	399	PF11976	0.463
LIG_SUMO_SIM_anti_2	622	628	PF11976	0.441
LIG_SUMO_SIM_anti_2	745	753	PF11976	0.332
LIG_SUMO_SIM_anti_2	860	868	PF11976	0.452
LIG_SUMO_SIM_par_1	493	499	PF11976	0.359
LIG_SUMO_SIM_par_1	745	753	PF11976	0.343
LIG_SUMO_SIM_par_1	987	993	PF11976	0.452
LIG_TRAF2_1	105	108	PF00917	0.695
LIG_TRAF2_1	13	16	PF00917	0.516
LIG_TRAF2_1	331	334	PF00917	0.691
LIG_TYR_ITIM	976	981	PF00017	0.293
LIG_UBA3_1	510	515	PF00899	0.383
LIG_UBA3_1	838	843	PF00899	0.293
LIG_UBA3_1	903	909	PF00899	0.411
LIG_WRC_WIRS_1	1023	1028	PF05994	0.510
MOD_CDK_SPK_2	1078	1083	PF00069	0.478
MOD_CDK_SPxK_1	1078	1084	PF00069	0.479
MOD_CDK_SPxxK_3	1078	1085	PF00069	0.479
MOD_CK1_1	1013	1019	PF00069	0.637
MOD_CK1_1	1025	1031	PF00069	0.686
MOD_CK1_1	1037	1043	PF00069	0.732
MOD_CK1_1	1046	1052	PF00069	0.727
MOD_CK1_1	1057	1063	PF00069	0.703
MOD_CK1_1	110	116	PF00069	0.461
MOD_CK1_1	201	207	PF00069	0.574
MOD_CK1_1	258	264	PF00069	0.726
MOD_CK1_1	266	272	PF00069	0.646
MOD_CK1_1	310	316	PF00069	0.689
MOD_CK1_1	393	399	PF00069	0.419
MOD_CK1_1	404	410	PF00069	0.307
MOD_CK1_1	485	491	PF00069	0.381
MOD_CK1_1	504	510	PF00069	0.340
MOD_CK1_1	635	641	PF00069	0.372
MOD_CK1_1	743	749	PF00069	0.353
MOD_CK1_1	829	835	PF00069	0.204
MOD_CK1_1	858	864	PF00069	0.397
MOD_CK1_1	91	97	PF00069	0.693
MOD_CK2_1	10	16	PF00069	0.516
MOD_CK2_1	205	211	PF00069	0.570
MOD_CK2_1	267	273	PF00069	0.542
MOD_CK2_1	328	334	PF00069	0.693
MOD_CK2_1	342	348	PF00069	0.590
MOD_CK2_1	357	363	PF00069	0.258
MOD_CK2_1	41	47	PF00069	0.631
MOD_CK2_1	732	738	PF00069	0.417
MOD_CK2_1	981	987	PF00069	0.302
MOD_CK2_1	990	996	PF00069	0.293
MOD_GlcNHglycan	1017	1020	PF01048	0.543
MOD_GlcNHglycan	1056	1059	PF01048	0.699
MOD_GlcNHglycan	1074	1077	PF01048	0.565
MOD_GlcNHglycan	134	137	PF01048	0.603
MOD_GlcNHglycan	165	168	PF01048	0.650
MOD_GlcNHglycan	198	201	PF01048	0.462
MOD_GlcNHglycan	228	231	PF01048	0.405
MOD_GlcNHglycan	257	260	PF01048	0.727
MOD_GlcNHglycan	330	333	PF01048	0.434
MOD_GlcNHglycan	392	395	PF01048	0.433
MOD_GlcNHglycan	403	406	PF01048	0.348
MOD_GlcNHglycan	529	532	PF01048	0.363
MOD_GlcNHglycan	538	541	PF01048	0.344
MOD_GlcNHglycan	634	637	PF01048	0.304
MOD_GlcNHglycan	67	71	PF01048	0.617
MOD_GlcNHglycan	831	834	PF01048	0.239
MOD_GlcNHglycan	96	99	PF01048	0.714
MOD_GlcNHglycan	963	966	PF01048	0.327
MOD_GSK3_1	1010	1017	PF00069	0.538
MOD_GSK3_1	1018	1025	PF00069	0.571
MOD_GSK3_1	1030	1037	PF00069	0.664
MOD_GSK3_1	1039	1046	PF00069	0.603
MOD_GSK3_1	1068	1075	PF00069	0.637
MOD_GSK3_1	148	155	PF00069	0.654
MOD_GSK3_1	163	170	PF00069	0.527
MOD_GSK3_1	188	195	PF00069	0.573
MOD_GSK3_1	201	208	PF00069	0.444
MOD_GSK3_1	258	265	PF00069	0.654
MOD_GSK3_1	307	314	PF00069	0.641
MOD_GSK3_1	328	335	PF00069	0.644
MOD_GSK3_1	401	408	PF00069	0.399
MOD_GSK3_1	451	458	PF00069	0.398
MOD_GSK3_1	462	469	PF00069	0.356
MOD_GSK3_1	628	635	PF00069	0.306
MOD_GSK3_1	710	717	PF00069	0.525
MOD_GSK3_1	739	746	PF00069	0.356
MOD_GSK3_1	786	793	PF00069	0.229
MOD_GSK3_1	822	829	PF00069	0.326
MOD_GSK3_1	851	858	PF00069	0.327
MOD_GSK3_1	89	96	PF00069	0.724
MOD_LATS_1	853	859	PF00433	0.397
MOD_N-GLC_1	858	863	PF02516	0.308
MOD_NEK2_1	1000	1005	PF00069	0.267
MOD_NEK2_1	1010	1015	PF00069	0.532
MOD_NEK2_1	132	137	PF00069	0.585
MOD_NEK2_1	139	144	PF00069	0.529
MOD_NEK2_1	196	201	PF00069	0.469
MOD_NEK2_1	224	229	PF00069	0.578
MOD_NEK2_1	263	268	PF00069	0.675
MOD_NEK2_1	300	305	PF00069	0.404
MOD_NEK2_1	356	361	PF00069	0.448
MOD_NEK2_1	399	404	PF00069	0.442
MOD_NEK2_1	451	456	PF00069	0.443
MOD_NEK2_1	461	466	PF00069	0.493
MOD_NEK2_1	480	485	PF00069	0.495
MOD_NEK2_1	526	531	PF00069	0.336
MOD_NEK2_1	678	683	PF00069	0.292
MOD_NEK2_1	750	755	PF00069	0.342
MOD_NEK2_1	786	791	PF00069	0.199
MOD_NEK2_1	812	817	PF00069	0.305
MOD_NEK2_1	822	827	PF00069	0.287
MOD_NEK2_1	954	959	PF00069	0.322
MOD_NEK2_1	981	986	PF00069	0.280
MOD_NEK2_2	1068	1073	PF00069	0.469
MOD_PIKK_1	110	116	PF00454	0.610
MOD_PIKK_1	405	411	PF00454	0.363
MOD_PIKK_1	41	47	PF00454	0.692
MOD_PIKK_1	426	432	PF00454	0.356
MOD_PIKK_1	696	702	PF00454	0.308
MOD_PIKK_1	868	874	PF00454	0.465
MOD_PIKK_1	898	904	PF00454	0.404
MOD_PKA_1	441	447	PF00069	0.407
MOD_PKA_1	536	542	PF00069	0.491
MOD_PKA_1	611	617	PF00069	0.360
MOD_PKA_1	943	949	PF00069	0.384
MOD_PKA_2	1010	1016	PF00069	0.468
MOD_PKA_2	1060	1066	PF00069	0.481
MOD_PKA_2	108	114	PF00069	0.510
MOD_PKA_2	178	184	PF00069	0.644
MOD_PKA_2	236	242	PF00069	0.662
MOD_PKA_2	441	447	PF00069	0.407
MOD_PKA_2	480	486	PF00069	0.473
MOD_PKA_2	611	617	PF00069	0.360
MOD_PKA_2	684	690	PF00069	0.413
MOD_PKA_2	711	717	PF00069	0.436
MOD_PKA_2	740	746	PF00069	0.368
MOD_PKA_2	773	779	PF00069	0.382
MOD_PKA_2	943	949	PF00069	0.296
MOD_Plk_1	139	145	PF00069	0.639
MOD_Plk_1	301	307	PF00069	0.497
MOD_Plk_1	501	507	PF00069	0.356
MOD_Plk_1	661	667	PF00069	0.281
MOD_Plk_1	822	828	PF00069	0.368
MOD_Plk_1	88	94	PF00069	0.490
MOD_Plk_4	1018	1024	PF00069	0.466
MOD_Plk_4	140	146	PF00069	0.575
MOD_Plk_4	393	399	PF00069	0.384
MOD_Plk_4	490	496	PF00069	0.357
MOD_Plk_4	620	626	PF00069	0.308
MOD_Plk_4	743	749	PF00069	0.341
MOD_Plk_4	773	779	PF00069	0.425
MOD_Plk_4	826	832	PF00069	0.194
MOD_Plk_4	862	868	PF00069	0.308
MOD_ProDKin_1	1030	1036	PF00069	0.757
MOD_ProDKin_1	1039	1045	PF00069	0.657
MOD_ProDKin_1	1046	1052	PF00069	0.575
MOD_ProDKin_1	1078	1084	PF00069	0.680
MOD_ProDKin_1	20	26	PF00069	0.735
MOD_ProDKin_1	559	565	PF00069	0.471
MOD_ProDKin_1	614	620	PF00069	0.413
MOD_ProDKin_1	644	650	PF00069	0.350
MOD_ProDKin_1	802	808	PF00069	0.417
MOD_SUMO_rev_2	280	289	PF00179	0.600
MOD_SUMO_rev_2	348	352	PF00179	0.520
MOD_SUMO_rev_2	829	838	PF00179	0.286
TRG_DiLeu_BaEn_1	996	1001	PF01217	0.327
TRG_DiLeu_BaEn_4	284	290	PF01217	0.472
TRG_DiLeu_BaLyEn_6	230	235	PF01217	0.477
TRG_DiLeu_BaLyEn_6	807	812	PF01217	0.187
TRG_DiLeu_LyEn_5	947	952	PF01217	0.378
TRG_ENDOCYTIC_2	240	243	PF00928	0.679
TRG_ENDOCYTIC_2	492	495	PF00928	0.341
TRG_ENDOCYTIC_2	948	951	PF00928	0.290
TRG_ENDOCYTIC_2	978	981	PF00928	0.293
TRG_ENDOCYTIC_2	988	991	PF00928	0.293
TRG_ER_diArg_1	1084	1086	PF00400	0.607
TRG_ER_diArg_1	336	339	PF00400	0.543
TRG_ER_diArg_1	370	372	PF00400	0.498
TRG_ER_diArg_1	431	433	PF00400	0.404
TRG_ER_diArg_1	441	443	PF00400	0.384
TRG_ER_diArg_1	518	521	PF00400	0.357
TRG_ER_diArg_1	609	612	PF00400	0.298
TRG_ER_diArg_1	706	709	PF00400	0.187
TRG_ER_diArg_1	943	945	PF00400	0.405
TRG_NLS_Bipartite_1	1073	1087	PF00514	0.697
TRG_NLS_MonoExtN_4	1082	1087	PF00514	0.606
TRG_Pf-PMV_PEXEL_1	1005	1009	PF00026	0.546
TRG_Pf-PMV_PEXEL_1	233	238	PF00026	0.413
TRG_Pf-PMV_PEXEL_1	388	392	PF00026	0.355
TRG_Pf-PMV_PEXEL_1	611	615	PF00026	0.308
TRG_Pf-PMV_PEXEL_1	810	814	PF00026	0.350
TRG_Pf-PMV_PEXEL_1	836	840	PF00026	0.293
TRG_PTS1	1085	1088	PF00515	0.700

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IKA7	Leptomonas seymouri	74%	100%
A0A0S4IR78	Bodo saltans	35%	100%
A0A0S4ITR4	Bodo saltans	48%	100%
A0A0S4IWU8	Bodo saltans	35%	100%
A0A1X0NVG5	Trypanosomatidae	52%	100%
A0A3Q8II71	Leishmania donovani	34%	100%
A0A3S7WYA1	Leishmania donovani	82%	100%
A0A3S7X7P0	Leishmania donovani	26%	71%
A0A422N8L3	Trypanosoma rangeli	53%	100%
A4HAT8	Leishmania braziliensis	34%	100%
A4HNU7	Leishmania braziliensis	33%	100%
A4I0U7	Leishmania infantum	82%	100%
A4IA06	Leishmania infantum	35%	100%
D0A2R5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	100%
D0A778	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	52%	100%
E9ASK7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	38%	100%
E9AWV1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	81%	88%
E9B512	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	100%
O42643	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	38%	93%
O45244	Caenorhabditis elegans	36%	100%
O60231	Homo sapiens	41%	100%
Q4Q2X4	Leishmania major	35%	100%
Q4QAM3	Leishmania major	81%	100%
Q54MH3	Dictyostelium discoideum	38%	98%
Q767K6	Sus scrofa	40%	100%
Q7YR39	Pan troglodytes	41%	100%
V5C0I9	Trypanosoma cruzi	60%	100%