Putative dynein light chain

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

dynein light chain, putative

Species:

Leishmania braziliensis

UniProt:

A4HDF9_LEIBR

TriTrypDb:

LbrM.24.1040 , LBRM2903_240016400

Length:

210

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 6
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 16

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005929	cilium	4	10
GO:0042995	cell projection	2	10
GO:0043226	organelle	2	10
GO:0043227	membrane-bounded organelle	3	10
GO:0110165	cellular anatomical entity	1	11
GO:0120025	plasma membrane bounded cell projection	3	10
GO:0005737	cytoplasm	2	1
GO:0005930	axoneme	2	1

Expansion

Sequence features

A4HDF9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HDF9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	191	195	PF00656	0.394
CLV_NRD_NRD_1	100	102	PF00675	0.217
CLV_NRD_NRD_1	21	23	PF00675	0.406
CLV_PCSK_KEX2_1	20	22	PF00082	0.453
CLV_PCSK_KEX2_1	208	210	PF00082	0.502
CLV_PCSK_SKI1_1	44	48	PF00082	0.345
CLV_PCSK_SKI1_1	85	89	PF00082	0.201
DEG_APCC_DBOX_1	19	27	PF00400	0.548
DOC_CDC14_PxL_1	184	192	PF14671	0.401
DOC_MAPK_gen_1	101	108	PF00069	0.401
DOC_MAPK_gen_1	129	138	PF00069	0.343
DOC_MAPK_gen_1	189	198	PF00069	0.401
DOC_MAPK_gen_1	85	95	PF00069	0.401
DOC_MAPK_MEF2A_6	65	72	PF00069	0.402
DOC_PP2B_LxvP_1	106	109	PF13499	0.401
DOC_PP4_MxPP_1	50	53	PF00568	0.390
DOC_USP7_MATH_1	30	34	PF00917	0.433
LIG_BIR_II_1	1	5	PF00653	0.430
LIG_BIR_III_3	1	5	PF00653	0.388
LIG_eIF4E_1	137	143	PF01652	0.414
LIG_FHA_1	72	78	PF00498	0.425
LIG_FHA_2	123	129	PF00498	0.414
LIG_FHA_2	145	151	PF00498	0.401
LIG_FHA_2	189	195	PF00498	0.394
LIG_FHA_2	61	67	PF00498	0.457
LIG_LIR_Gen_1	117	124	PF02991	0.401
LIG_LIR_Gen_1	145	153	PF02991	0.404
LIG_LIR_Gen_1	178	188	PF02991	0.428
LIG_LIR_Nem_3	112	118	PF02991	0.401
LIG_LIR_Nem_3	145	149	PF02991	0.405
LIG_LIR_Nem_3	178	184	PF02991	0.433
LIG_LRP6_Inhibitor_1	95	101	PF00058	0.201
LIG_MAD2	44	52	PF02301	0.368
LIG_MYND_3	108	112	PF01753	0.457
LIG_NRP_CendR_1	208	210	PF00754	0.502
LIG_SH2_CRK	181	185	PF00017	0.443
LIG_SH2_NCK_1	118	122	PF00017	0.401
LIG_SH2_STAT5	137	140	PF00017	0.343
LIG_SH3_3	194	200	PF00018	0.414
LIG_SUMO_SIM_anti_2	158	164	PF11976	0.414
LIG_TRAF2_1	175	178	PF00917	0.432
LIG_TRAF2_1	29	32	PF00917	0.482
LIG_TRAF2_1	39	42	PF00917	0.353
LIG_UBA3_1	183	189	PF00899	0.414
LIG_UBA3_1	47	56	PF00899	0.358
MOD_CK1_1	172	178	PF00069	0.494
MOD_CK1_1	3	9	PF00069	0.509
MOD_CK2_1	142	148	PF00069	0.402
MOD_CK2_1	172	178	PF00069	0.414
MOD_CK2_1	3	9	PF00069	0.397
MOD_CK2_1	60	66	PF00069	0.493
MOD_GlcNHglycan	171	174	PF01048	0.295
MOD_GlcNHglycan	2	5	PF01048	0.510
MOD_N-GLC_2	154	156	PF02516	0.201
MOD_NEK2_1	114	119	PF00069	0.401
MOD_NEK2_1	136	141	PF00069	0.401
MOD_NEK2_1	142	147	PF00069	0.401
MOD_NEK2_1	70	75	PF00069	0.238
MOD_NEK2_2	96	101	PF00069	0.343
MOD_PKA_2	96	102	PF00069	0.429
MOD_Plk_1	59	65	PF00069	0.409
MOD_Plk_2-3	60	66	PF00069	0.493
TRG_DiLeu_BaEn_1	42	47	PF01217	0.334
TRG_ENDOCYTIC_2	118	121	PF00928	0.414
TRG_ENDOCYTIC_2	179	182	PF00928	0.427
TRG_ER_diArg_1	19	22	PF00400	0.429
TRG_ER_diArg_1	208	210	PF00400	0.504
TRG_Pf-PMV_PEXEL_1	101	105	PF00026	0.201

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A096MJZ0	Rattus norvegicus	43%	100%
A0A0N1PBU3	Leptomonas seymouri	90%	100%
A0A0S4JQV7	Bodo saltans	72%	99%
A0A1X0NVY4	Trypanosomatidae	80%	100%
A0A3Q8IC25	Leishmania donovani	93%	100%
A0A3R7LR73	Trypanosoma rangeli	78%	100%
A4I0U0	Leishmania infantum	93%	100%
D0A771	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	75%	100%
D0A8W7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	73%
E9ATS2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	67%
E9AWU4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
Q05A62	Mus musculus	43%	100%
Q28G94	Xenopus tropicalis	42%	100%
Q2KID4	Bos taurus	43%	100%
Q4LDG9	Homo sapiens	43%	100%
Q4QAN0	Leishmania major	93%	100%
Q641R9	Xenopus laevis	42%	100%
Q6DHB1	Danio rerio	44%	100%
Q8T888	Ciona intestinalis	41%	100%
Q9XHH2	Chlamydomonas reinhardtii	49%	100%