LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HDE2_LEIBR
TriTrypDb:
LbrM.24.0870 , LBRM2903_240014700 *
Length:
73

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HDE2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HDE2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 67 69 PF00675 0.686
CLV_PCSK_KEX2_1 67 69 PF00082 0.686
DEG_Nend_UBRbox_3 1 3 PF02207 0.840
DOC_CDC14_PxL_1 32 40 PF14671 0.662
DOC_USP7_UBL2_3 47 51 PF12436 0.679
LIG_FHA_1 25 31 PF00498 0.642
LIG_LIR_Gen_1 42 53 PF02991 0.675
LIG_LIR_Nem_3 42 48 PF02991 0.674
LIG_SH2_STAT5 32 35 PF00017 0.661
LIG_TYR_ITIM 30 35 PF00017 0.657
MOD_GSK3_1 2 9 PF00069 0.818
MOD_GSK3_1 63 70 PF00069 0.691
MOD_LATS_1 4 10 PF00433 0.811
MOD_NEK2_1 19 24 PF00069 0.649
MOD_PIKK_1 67 73 PF00454 0.730
MOD_PKA_1 67 73 PF00069 0.730
MOD_PKA_2 63 69 PF00069 0.688
MOD_SUMO_rev_2 12 19 PF00179 0.696
TRG_ENDOCYTIC_2 32 35 PF00928 0.661

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS