Putative DNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein, putative

Species:

Leishmania braziliensis

UniProt:

A4HDB9_LEIBR

TriTrypDb:

LbrM.24.0620 , LBRM2903_240012000

Length:

1096

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	7
GO:0043226	organelle	2	7
GO:0043227	membrane-bounded organelle	3	7
GO:0043229	intracellular organelle	3	7
GO:0043231	intracellular membrane-bounded organelle	4	7
GO:0110165	cellular anatomical entity	1	8
GO:0005657	replication fork	2	1
GO:0043596	nuclear replication fork	3	1

Expansion

Sequence features

A4HDB9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HDB9

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	9
GO:0006259	DNA metabolic process	4	9
GO:0006281	DNA repair	5	9
GO:0006725	cellular aromatic compound metabolic process	3	9
GO:0006807	nitrogen compound metabolic process	2	9
GO:0006950	response to stress	2	9
GO:0006974	DNA damage response	4	9
GO:0008152	metabolic process	1	9
GO:0009987	cellular process	1	9
GO:0031297	replication fork processing	6	9
GO:0033554	cellular response to stress	3	9
GO:0034641	cellular nitrogen compound metabolic process	3	9
GO:0043170	macromolecule metabolic process	3	9
GO:0044237	cellular metabolic process	2	9
GO:0044238	primary metabolic process	2	9
GO:0044260	obsolete cellular macromolecule metabolic process	3	9
GO:0045005	DNA-templated DNA replication maintenance of fidelity	5	9
GO:0046483	heterocycle metabolic process	3	9
GO:0050896	response to stimulus	1	9
GO:0051716	cellular response to stimulus	2	9
GO:0071704	organic substance metabolic process	2	9
GO:0090304	nucleic acid metabolic process	4	9
GO:1901360	organic cyclic compound metabolic process	3	9
GO:0006275	regulation of DNA replication	6	1
GO:0008156	negative regulation of DNA replication	7	1
GO:0009892	negative regulation of metabolic process	4	1
GO:0010605	negative regulation of macromolecule metabolic process	5	1
GO:0019219	regulation of nucleobase-containing compound metabolic process	5	1
GO:0019222	regulation of metabolic process	3	1
GO:0031323	regulation of cellular metabolic process	4	1
GO:0031324	negative regulation of cellular metabolic process	5	1
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	6	1
GO:0048478	obsolete replication fork protection	6	1
GO:0048519	negative regulation of biological process	3	1
GO:0048523	negative regulation of cellular process	4	1
GO:0050789	regulation of biological process	2	1
GO:0050794	regulation of cellular process	3	1
GO:0051052	regulation of DNA metabolic process	5	1
GO:0051053	negative regulation of DNA metabolic process	6	1
GO:0051171	regulation of nitrogen compound metabolic process	4	1
GO:0051172	negative regulation of nitrogen compound metabolic process	5	1
GO:0060255	regulation of macromolecule metabolic process	4	1
GO:0065007	biological regulation	1	1
GO:0080090	regulation of primary metabolic process	4	1
GO:0090329	regulation of DNA-templated DNA replication	7	1
GO:2000104	negative regulation of DNA-templated DNA replication	8	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	10
GO:0003676	nucleic acid binding	3	9
GO:0003677	DNA binding	4	9
GO:0003697	single-stranded DNA binding	5	9
GO:0003824	catalytic activity	1	10
GO:0004386	helicase activity	2	7
GO:0005488	binding	1	10
GO:0005524	ATP binding	5	10
GO:0008094	ATP-dependent activity, acting on DNA	2	10
GO:0016491	oxidoreductase activity	2	10
GO:0017076	purine nucleotide binding	4	10
GO:0030554	adenyl nucleotide binding	5	10
GO:0032553	ribonucleotide binding	3	10
GO:0032555	purine ribonucleotide binding	4	10
GO:0032559	adenyl ribonucleotide binding	5	10
GO:0035639	purine ribonucleoside triphosphate binding	4	10
GO:0036094	small molecule binding	2	10
GO:0036310	ATP-dependent DNA/DNA annealing activity	2	9
GO:0043167	ion binding	2	10
GO:0043168	anion binding	3	10
GO:0051213	dioxygenase activity	3	10
GO:0097159	organic cyclic compound binding	2	10
GO:0097367	carbohydrate derivative binding	2	10
GO:0140097	catalytic activity, acting on DNA	3	10
GO:0140640	catalytic activity, acting on a nucleic acid	2	10
GO:0140657	ATP-dependent activity	1	10
GO:0140658	ATP-dependent chromatin remodeler activity	3	10
GO:0140666	annealing activity	4	9
GO:1901265	nucleoside phosphate binding	3	10
GO:1901363	heterocyclic compound binding	2	10
GO:1990814	DNA/DNA annealing activity	5	9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	436	440	PF00656	0.562
CLV_C14_Caspase3-7	678	682	PF00656	0.723
CLV_C14_Caspase3-7	841	845	PF00656	0.525
CLV_NRD_NRD_1	1073	1075	PF00675	0.679
CLV_NRD_NRD_1	312	314	PF00675	0.305
CLV_NRD_NRD_1	382	384	PF00675	0.269
CLV_NRD_NRD_1	641	643	PF00675	0.596
CLV_NRD_NRD_1	742	744	PF00675	0.559
CLV_NRD_NRD_1	792	794	PF00675	0.627
CLV_NRD_NRD_1	836	838	PF00675	0.637
CLV_NRD_NRD_1	897	899	PF00675	0.634
CLV_PCSK_FUR_1	383	387	PF00082	0.266
CLV_PCSK_KEX2_1	1073	1075	PF00082	0.679
CLV_PCSK_KEX2_1	299	301	PF00082	0.274
CLV_PCSK_KEX2_1	312	314	PF00082	0.234
CLV_PCSK_KEX2_1	382	384	PF00082	0.269
CLV_PCSK_KEX2_1	385	387	PF00082	0.269
CLV_PCSK_KEX2_1	641	643	PF00082	0.596
CLV_PCSK_KEX2_1	742	744	PF00082	0.559
CLV_PCSK_KEX2_1	792	794	PF00082	0.627
CLV_PCSK_KEX2_1	836	838	PF00082	0.590
CLV_PCSK_KEX2_1	897	899	PF00082	0.634
CLV_PCSK_KEX2_1	958	960	PF00082	0.661
CLV_PCSK_PC1ET2_1	299	301	PF00082	0.309
CLV_PCSK_PC1ET2_1	385	387	PF00082	0.266
CLV_PCSK_PC1ET2_1	958	960	PF00082	0.694
CLV_PCSK_SKI1_1	1074	1078	PF00082	0.677
CLV_PCSK_SKI1_1	187	191	PF00082	0.410
CLV_PCSK_SKI1_1	313	317	PF00082	0.274
CLV_PCSK_SKI1_1	397	401	PF00082	0.201
CLV_PCSK_SKI1_1	409	413	PF00082	0.256
CLV_PCSK_SKI1_1	456	460	PF00082	0.392
CLV_PCSK_SKI1_1	484	488	PF00082	0.273
CLV_PCSK_SKI1_1	591	595	PF00082	0.360
CLV_PCSK_SKI1_1	898	902	PF00082	0.697
DEG_APCC_DBOX_1	1072	1080	PF00400	0.678
DEG_COP1_1	851	859	PF00400	0.496
DEG_Nend_UBRbox_3	1	3	PF02207	0.468
DEG_ODPH_VHL_1	33	46	PF01847	0.600
DEG_SCF_FBW7_1	317	324	PF00400	0.456
DEG_SCF_FBW7_1	912	918	PF00400	0.521
DEG_SPOP_SBC_1	1050	1054	PF00917	0.666
DEG_SPOP_SBC_1	1060	1064	PF00917	0.550
DEG_SPOP_SBC_1	821	825	PF00917	0.546
DEG_SPOP_SBC_1	920	924	PF00917	0.604
DOC_CKS1_1	671	676	PF01111	0.612
DOC_CKS1_1	717	722	PF01111	0.683
DOC_CKS1_1	734	739	PF01111	0.665
DOC_CKS1_1	761	766	PF01111	0.591
DOC_CKS1_1	912	917	PF01111	0.520
DOC_CYCLIN_RxL_1	1071	1081	PF00134	0.560
DOC_CYCLIN_RxL_1	588	598	PF00134	0.364
DOC_MAPK_DCC_7	126	135	PF00069	0.494
DOC_MAPK_FxFP_2	111	114	PF00069	0.379
DOC_MAPK_gen_1	126	135	PF00069	0.412
DOC_MAPK_gen_1	299	307	PF00069	0.467
DOC_MAPK_gen_1	309	317	PF00069	0.448
DOC_MAPK_gen_1	395	404	PF00069	0.468
DOC_MAPK_MEF2A_6	126	135	PF00069	0.494
DOC_MAPK_MEF2A_6	218	226	PF00069	0.461
DOC_MAPK_MEF2A_6	395	404	PF00069	0.418
DOC_MAPK_MEF2A_6	711	718	PF00069	0.680
DOC_MAPK_MEF2A_6	86	94	PF00069	0.528
DOC_MAPK_MEF2A_6	943	951	PF00069	0.656
DOC_PP1_RVXF_1	482	489	PF00149	0.469
DOC_PP2B_LxvP_1	46	49	PF13499	0.580
DOC_PP2B_LxvP_1	936	939	PF13499	0.505
DOC_PP2B_PxIxI_1	130	136	PF00149	0.323
DOC_PP4_FxxP_1	111	114	PF00568	0.379
DOC_PP4_FxxP_1	664	667	PF00568	0.685
DOC_SPAK_OSR1_1	358	362	PF12202	0.481
DOC_USP7_MATH_1	1016	1020	PF00917	0.648
DOC_USP7_MATH_1	1050	1054	PF00917	0.808
DOC_USP7_MATH_1	1067	1071	PF00917	0.670
DOC_USP7_MATH_1	301	305	PF00917	0.550
DOC_USP7_MATH_1	321	325	PF00917	0.464
DOC_USP7_MATH_1	340	344	PF00917	0.366
DOC_USP7_MATH_1	393	397	PF00917	0.481
DOC_USP7_MATH_1	430	434	PF00917	0.647
DOC_USP7_MATH_1	497	501	PF00917	0.495
DOC_USP7_MATH_1	646	650	PF00917	0.720
DOC_USP7_MATH_1	653	657	PF00917	0.704
DOC_USP7_MATH_1	667	671	PF00917	0.720
DOC_USP7_MATH_1	745	749	PF00917	0.656
DOC_USP7_MATH_1	783	787	PF00917	0.644
DOC_USP7_MATH_1	821	825	PF00917	0.660
DOC_USP7_MATH_1	859	863	PF00917	0.686
DOC_USP7_MATH_1	908	912	PF00917	0.680
DOC_USP7_MATH_1	915	919	PF00917	0.693
DOC_USP7_UBL2_3	237	241	PF12436	0.508
DOC_USP7_UBL2_3	410	414	PF12436	0.487
DOC_WW_Pin1_4	1026	1031	PF00397	0.501
DOC_WW_Pin1_4	1052	1057	PF00397	0.690
DOC_WW_Pin1_4	1061	1066	PF00397	0.752
DOC_WW_Pin1_4	1086	1091	PF00397	0.678
DOC_WW_Pin1_4	317	322	PF00397	0.471
DOC_WW_Pin1_4	517	522	PF00397	0.487
DOC_WW_Pin1_4	649	654	PF00397	0.685
DOC_WW_Pin1_4	670	675	PF00397	0.554
DOC_WW_Pin1_4	687	692	PF00397	0.660
DOC_WW_Pin1_4	705	710	PF00397	0.686
DOC_WW_Pin1_4	716	721	PF00397	0.623
DOC_WW_Pin1_4	733	738	PF00397	0.605
DOC_WW_Pin1_4	760	765	PF00397	0.606
DOC_WW_Pin1_4	815	820	PF00397	0.606
DOC_WW_Pin1_4	848	853	PF00397	0.544
DOC_WW_Pin1_4	878	883	PF00397	0.678
DOC_WW_Pin1_4	904	909	PF00397	0.577
DOC_WW_Pin1_4	911	916	PF00397	0.633
DOC_WW_Pin1_4	921	926	PF00397	0.519
LIG_14-3-3_CanoR_1	1035	1044	PF00244	0.618
LIG_14-3-3_CanoR_1	1073	1077	PF00244	0.680
LIG_14-3-3_CanoR_1	300	306	PF00244	0.481
LIG_14-3-3_CanoR_1	350	356	PF00244	0.483
LIG_14-3-3_CanoR_1	420	424	PF00244	0.491
LIG_14-3-3_CanoR_1	43	47	PF00244	0.602
LIG_14-3-3_CanoR_1	726	734	PF00244	0.656
LIG_14-3-3_CanoR_1	742	750	PF00244	0.554
LIG_14-3-3_CanoR_1	795	805	PF00244	0.684
LIG_14-3-3_CanoR_1	897	901	PF00244	0.697
LIG_Actin_WH2_2	259	277	PF00022	0.523
LIG_Actin_WH2_2	495	511	PF00022	0.399
LIG_APCC_ABBA_1	767	772	PF00400	0.659
LIG_BIR_III_2	712	716	PF00653	0.616
LIG_CtBP_PxDLS_1	811	815	PF00389	0.542
LIG_deltaCOP1_diTrp_1	101	111	PF00928	0.503
LIG_deltaCOP1_diTrp_1	233	242	PF00928	0.456
LIG_eIF4E_1	7	13	PF01652	0.356
LIG_FHA_1	117	123	PF00498	0.532
LIG_FHA_1	20	26	PF00498	0.534
LIG_FHA_1	535	541	PF00498	0.490
LIG_FHA_1	54	60	PF00498	0.465
LIG_FHA_1	613	619	PF00498	0.467
LIG_FHA_1	749	755	PF00498	0.534
LIG_FHA_1	75	81	PF00498	0.288
LIG_FHA_1	800	806	PF00498	0.547
LIG_FHA_1	871	877	PF00498	0.815
LIG_FHA_1	925	931	PF00498	0.614
LIG_FHA_1	942	948	PF00498	0.651
LIG_FHA_1	986	992	PF00498	0.531
LIG_FHA_2	382	388	PF00498	0.481
LIG_FHA_2	403	409	PF00498	0.456
LIG_FHA_2	561	567	PF00498	0.456
LIG_FHA_2	638	644	PF00498	0.589
LIG_FHA_2	730	736	PF00498	0.526
LIG_FHA_2	839	845	PF00498	0.521
LIG_FHA_2	935	941	PF00498	0.559
LIG_LIR_Apic_2	662	667	PF02991	0.674
LIG_LIR_Gen_1	116	125	PF02991	0.307
LIG_LIR_Gen_1	238	247	PF02991	0.523
LIG_LIR_Gen_1	270	277	PF02991	0.501
LIG_LIR_Gen_1	328	338	PF02991	0.468
LIG_LIR_Gen_1	39	49	PF02991	0.618
LIG_LIR_Gen_1	433	442	PF02991	0.441
LIG_LIR_Gen_1	512	521	PF02991	0.456
LIG_LIR_Gen_1	559	569	PF02991	0.523
LIG_LIR_Gen_1	85	95	PF02991	0.522
LIG_LIR_Nem_3	116	121	PF02991	0.308
LIG_LIR_Nem_3	172	178	PF02991	0.363
LIG_LIR_Nem_3	220	224	PF02991	0.456
LIG_LIR_Nem_3	238	242	PF02991	0.507
LIG_LIR_Nem_3	270	274	PF02991	0.489
LIG_LIR_Nem_3	328	333	PF02991	0.468
LIG_LIR_Nem_3	39	44	PF02991	0.556
LIG_LIR_Nem_3	433	438	PF02991	0.441
LIG_LIR_Nem_3	512	516	PF02991	0.456
LIG_LIR_Nem_3	559	565	PF02991	0.523
LIG_LIR_Nem_3	601	607	PF02991	0.463
LIG_LIR_Nem_3	85	90	PF02991	0.533
LIG_MYND_1	765	769	PF01753	0.663
LIG_MYND_2	764	768	PF01753	0.660
LIG_NRBOX	371	377	PF00104	0.523
LIG_Pex14_1	235	239	PF04695	0.535
LIG_Pex14_2	100	104	PF04695	0.439
LIG_Pex14_2	355	359	PF04695	0.523
LIG_PTB_Apo_2	137	144	PF02174	0.278
LIG_Rb_LxCxE_1	270	290	PF01857	0.484
LIG_SH2_CRK	175	179	PF00017	0.460
LIG_SH2_CRK	271	275	PF00017	0.463
LIG_SH2_CRK	330	334	PF00017	0.456
LIG_SH2_CRK	41	45	PF00017	0.610
LIG_SH2_NCK_1	31	35	PF00017	0.563
LIG_SH2_NCK_1	41	45	PF00017	0.610
LIG_SH2_PTP2	401	404	PF00017	0.396
LIG_SH2_PTP2	513	516	PF00017	0.456
LIG_SH2_SRC	11	14	PF00017	0.526
LIG_SH2_SRC	401	404	PF00017	0.395
LIG_SH2_SRC	513	516	PF00017	0.523
LIG_SH2_STAP1	118	122	PF00017	0.424
LIG_SH2_STAP1	156	160	PF00017	0.476
LIG_SH2_STAP1	21	25	PF00017	0.435
LIG_SH2_STAT5	105	108	PF00017	0.461
LIG_SH2_STAT5	11	14	PF00017	0.466
LIG_SH2_STAT5	118	121	PF00017	0.522
LIG_SH2_STAT5	142	145	PF00017	0.442
LIG_SH2_STAT5	21	24	PF00017	0.376
LIG_SH2_STAT5	292	295	PF00017	0.475
LIG_SH2_STAT5	351	354	PF00017	0.460
LIG_SH2_STAT5	379	382	PF00017	0.437
LIG_SH2_STAT5	401	404	PF00017	0.452
LIG_SH2_STAT5	41	44	PF00017	0.391
LIG_SH2_STAT5	470	473	PF00017	0.371
LIG_SH2_STAT5	513	516	PF00017	0.456
LIG_SH2_STAT5	592	595	PF00017	0.339
LIG_SH3_3	1025	1031	PF00018	0.769
LIG_SH3_3	1084	1090	PF00018	0.680
LIG_SH3_3	222	228	PF00018	0.549
LIG_SH3_3	46	52	PF00018	0.543
LIG_SH3_3	504	510	PF00018	0.455
LIG_SH3_3	599	605	PF00018	0.412
LIG_SH3_3	717	723	PF00018	0.652
LIG_SH3_3	758	764	PF00018	0.625
LIG_SH3_3	804	810	PF00018	0.661
LIG_SH3_3	882	888	PF00018	0.730
LIG_SH3_3	890	896	PF00018	0.644
LIG_SH3_3	936	942	PF00018	0.741
LIG_SH3_3	944	950	PF00018	0.690
LIG_SUMO_SIM_anti_2	248	254	PF11976	0.437
LIG_SUMO_SIM_anti_2	265	270	PF11976	0.395
LIG_SUMO_SIM_anti_2	539	544	PF11976	0.524
LIG_SUMO_SIM_anti_2	830	836	PF11976	0.693
LIG_SUMO_SIM_par_1	265	270	PF11976	0.437
LIG_SUMO_SIM_par_1	283	290	PF11976	0.481
LIG_SUMO_SIM_par_1	537	544	PF11976	0.523
LIG_SUMO_SIM_par_1	714	719	PF11976	0.818
LIG_SUMO_SIM_par_1	810	816	PF11976	0.558
LIG_SUMO_SIM_par_1	934	940	PF11976	0.504
LIG_TRAF2_1	134	137	PF00917	0.447
LIG_TRAF2_2	153	158	PF00917	0.458
LIG_TRFH_1	31	35	PF08558	0.563
LIG_TYR_ITIM	269	274	PF00017	0.458
LIG_TYR_ITIM	399	404	PF00017	0.456
LIG_TYR_ITIM	511	516	PF00017	0.456
LIG_UBA3_1	121	126	PF00899	0.343
LIG_UBA3_1	399	407	PF00899	0.523
LIG_WW_3	894	898	PF00397	0.596
MOD_CDC14_SPxK_1	708	711	PF00782	0.529
MOD_CDK_SPK_2	687	692	PF00069	0.694
MOD_CDK_SPxK_1	670	676	PF00069	0.555
MOD_CDK_SPxK_1	705	711	PF00069	0.540
MOD_CK1_1	1008	1014	PF00069	0.506
MOD_CK1_1	1029	1035	PF00069	0.558
MOD_CK1_1	1052	1058	PF00069	0.703
MOD_CK1_1	1059	1065	PF00069	0.653
MOD_CK1_1	1081	1087	PF00069	0.530
MOD_CK1_1	270	276	PF00069	0.508
MOD_CK1_1	422	428	PF00069	0.607
MOD_CK1_1	433	439	PF00069	0.592
MOD_CK1_1	517	523	PF00069	0.523
MOD_CK1_1	544	550	PF00069	0.529
MOD_CK1_1	612	618	PF00069	0.469
MOD_CK1_1	621	627	PF00069	0.662
MOD_CK1_1	649	655	PF00069	0.691
MOD_CK1_1	656	662	PF00069	0.603
MOD_CK1_1	670	676	PF00069	0.542
MOD_CK1_1	686	692	PF00069	0.630
MOD_CK1_1	697	703	PF00069	0.687
MOD_CK1_1	741	747	PF00069	0.532
MOD_CK1_1	748	754	PF00069	0.525
MOD_CK1_1	786	792	PF00069	0.753
MOD_CK1_1	797	803	PF00069	0.631
MOD_CK1_1	813	819	PF00069	0.723
MOD_CK1_1	840	846	PF00069	0.590
MOD_CK1_1	872	878	PF00069	0.631
MOD_CK1_1	880	886	PF00069	0.694
MOD_CK1_1	911	917	PF00069	0.631
MOD_CK1_1	918	924	PF00069	0.651
MOD_CK2_1	227	233	PF00069	0.481
MOD_CK2_1	381	387	PF00069	0.487
MOD_CK2_1	402	408	PF00069	0.462
MOD_CK2_1	497	503	PF00069	0.508
MOD_CK2_1	621	627	PF00069	0.689
MOD_CK2_1	82	88	PF00069	0.431
MOD_CK2_1	934	940	PF00069	0.643
MOD_GlcNHglycan	1010	1013	PF01048	0.584
MOD_GlcNHglycan	1016	1019	PF01048	0.587
MOD_GlcNHglycan	1069	1072	PF01048	0.677
MOD_GlcNHglycan	1083	1086	PF01048	0.818
MOD_GlcNHglycan	161	164	PF01048	0.347
MOD_GlcNHglycan	317	320	PF01048	0.271
MOD_GlcNHglycan	432	435	PF01048	0.575
MOD_GlcNHglycan	439	443	PF01048	0.530
MOD_GlcNHglycan	471	474	PF01048	0.456
MOD_GlcNHglycan	480	483	PF01048	0.323
MOD_GlcNHglycan	499	502	PF01048	0.323
MOD_GlcNHglycan	516	519	PF01048	0.217
MOD_GlcNHglycan	547	550	PF01048	0.332
MOD_GlcNHglycan	623	626	PF01048	0.595
MOD_GlcNHglycan	738	741	PF01048	0.665
MOD_GlcNHglycan	743	746	PF01048	0.639
MOD_GlcNHglycan	747	750	PF01048	0.620
MOD_GlcNHglycan	788	791	PF01048	0.749
MOD_GlcNHglycan	796	799	PF01048	0.610
MOD_GlcNHglycan	824	827	PF01048	0.700
MOD_GlcNHglycan	846	849	PF01048	0.702
MOD_GlcNHglycan	857	860	PF01048	0.662
MOD_GSK3_1	1010	1017	PF00069	0.508
MOD_GSK3_1	1022	1029	PF00069	0.488
MOD_GSK3_1	1050	1057	PF00069	0.746
MOD_GSK3_1	1059	1066	PF00069	0.688
MOD_GSK3_1	1081	1088	PF00069	0.809
MOD_GSK3_1	317	324	PF00069	0.478
MOD_GSK3_1	419	426	PF00069	0.528
MOD_GSK3_1	541	548	PF00069	0.523
MOD_GSK3_1	552	559	PF00069	0.535
MOD_GSK3_1	617	624	PF00069	0.613
MOD_GSK3_1	647	654	PF00069	0.710
MOD_GSK3_1	683	690	PF00069	0.687
MOD_GSK3_1	694	701	PF00069	0.600
MOD_GSK3_1	729	736	PF00069	0.662
MOD_GSK3_1	741	748	PF00069	0.570
MOD_GSK3_1	750	757	PF00069	0.598
MOD_GSK3_1	815	822	PF00069	0.601
MOD_GSK3_1	836	843	PF00069	0.605
MOD_GSK3_1	844	851	PF00069	0.574
MOD_GSK3_1	855	862	PF00069	0.497
MOD_GSK3_1	865	872	PF00069	0.662
MOD_GSK3_1	877	884	PF00069	0.694
MOD_GSK3_1	899	906	PF00069	0.728
MOD_GSK3_1	911	918	PF00069	0.628
MOD_GSK3_1	920	927	PF00069	0.692
MOD_GSK3_1	993	1000	PF00069	0.567
MOD_N-GLC_1	1081	1086	PF02516	0.549
MOD_N-GLC_1	552	557	PF02516	0.256
MOD_N-GLC_1	621	626	PF02516	0.592
MOD_N-GLC_1	637	642	PF02516	0.475
MOD_N-GLC_1	786	791	PF02516	0.685
MOD_N-GLC_1	908	913	PF02516	0.511
MOD_NEK2_1	103	108	PF00069	0.435
MOD_NEK2_1	1049	1054	PF00069	0.696
MOD_NEK2_1	204	209	PF00069	0.485
MOD_NEK2_1	287	292	PF00069	0.488
MOD_NEK2_1	419	424	PF00069	0.496
MOD_NEK2_1	53	58	PF00069	0.564
MOD_NEK2_1	545	550	PF00069	0.504
MOD_NEK2_1	611	616	PF00069	0.419
MOD_NEK2_1	617	622	PF00069	0.480
MOD_NEK2_1	647	652	PF00069	0.545
MOD_NEK2_1	729	734	PF00069	0.643
MOD_NEK2_1	754	759	PF00069	0.605
MOD_NEK2_1	777	782	PF00069	0.746
MOD_NEK2_1	788	793	PF00069	0.708
MOD_NEK2_1	796	801	PF00069	0.631
MOD_NEK2_1	835	840	PF00069	0.690
MOD_NEK2_1	867	872	PF00069	0.607
MOD_NEK2_1	901	906	PF00069	0.559
MOD_NEK2_1	919	924	PF00069	0.686
MOD_NEK2_1	986	991	PF00069	0.639
MOD_NEK2_2	1072	1077	PF00069	0.652
MOD_NEK2_2	301	306	PF00069	0.533
MOD_NEK2_2	74	79	PF00069	0.280
MOD_NEK2_2	896	901	PF00069	0.608
MOD_PIKK_1	1036	1042	PF00454	0.661
MOD_PIKK_1	113	119	PF00454	0.332
MOD_PIKK_1	653	659	PF00454	0.644
MOD_PIKK_1	667	673	PF00454	0.604
MOD_PIKK_1	694	700	PF00454	0.618
MOD_PIKK_1	721	727	PF00454	0.788
MOD_PIKK_1	805	811	PF00454	0.800
MOD_PIKK_1	870	876	PF00454	0.815
MOD_PKA_1	836	842	PF00069	0.590
MOD_PKA_2	1072	1078	PF00069	0.674
MOD_PKA_2	308	314	PF00069	0.479
MOD_PKA_2	381	387	PF00069	0.481
MOD_PKA_2	419	425	PF00069	0.490
MOD_PKA_2	42	48	PF00069	0.594
MOD_PKA_2	741	747	PF00069	0.633
MOD_PKA_2	794	800	PF00069	0.774
MOD_PKA_2	835	841	PF00069	0.675
MOD_PKA_2	896	902	PF00069	0.690
MOD_Plk_1	287	293	PF00069	0.456
MOD_Plk_1	82	88	PF00069	0.526
MOD_Plk_1	908	914	PF00069	0.514
MOD_Plk_4	227	233	PF00069	0.465
MOD_Plk_4	351	357	PF00069	0.472
MOD_Plk_4	371	377	PF00069	0.523
MOD_Plk_4	556	562	PF00069	0.475
MOD_Plk_4	598	604	PF00069	0.401
MOD_Plk_4	683	689	PF00069	0.529
MOD_Plk_4	729	735	PF00069	0.671
MOD_Plk_4	827	833	PF00069	0.688
MOD_Plk_4	851	857	PF00069	0.535
MOD_Plk_4	872	878	PF00069	0.561
MOD_Plk_4	915	921	PF00069	0.553
MOD_ProDKin_1	1026	1032	PF00069	0.504
MOD_ProDKin_1	1052	1058	PF00069	0.690
MOD_ProDKin_1	1061	1067	PF00069	0.744
MOD_ProDKin_1	1086	1092	PF00069	0.675
MOD_ProDKin_1	317	323	PF00069	0.471
MOD_ProDKin_1	517	523	PF00069	0.487
MOD_ProDKin_1	649	655	PF00069	0.685
MOD_ProDKin_1	670	676	PF00069	0.555
MOD_ProDKin_1	687	693	PF00069	0.662
MOD_ProDKin_1	705	711	PF00069	0.684
MOD_ProDKin_1	716	722	PF00069	0.623
MOD_ProDKin_1	733	739	PF00069	0.607
MOD_ProDKin_1	760	766	PF00069	0.608
MOD_ProDKin_1	815	821	PF00069	0.600
MOD_ProDKin_1	848	854	PF00069	0.542
MOD_ProDKin_1	878	884	PF00069	0.680
MOD_ProDKin_1	904	910	PF00069	0.576
MOD_ProDKin_1	911	917	PF00069	0.634
MOD_ProDKin_1	921	927	PF00069	0.519
MOD_SUMO_rev_2	14	19	PF00179	0.549
MOD_SUMO_rev_2	406	412	PF00179	0.523
TRG_DiLeu_BaEn_1	220	225	PF01217	0.456
TRG_DiLeu_BaEn_1	371	376	PF01217	0.481
TRG_DiLeu_BaLyEn_6	602	607	PF01217	0.385
TRG_DiLeu_BaLyEn_6	712	717	PF01217	0.718
TRG_ENDOCYTIC_2	118	121	PF00928	0.429
TRG_ENDOCYTIC_2	175	178	PF00928	0.456
TRG_ENDOCYTIC_2	271	274	PF00928	0.469
TRG_ENDOCYTIC_2	330	333	PF00928	0.456
TRG_ENDOCYTIC_2	401	404	PF00928	0.462
TRG_ENDOCYTIC_2	41	44	PF00928	0.611
TRG_ENDOCYTIC_2	513	516	PF00928	0.456
TRG_ER_diArg_1	1072	1074	PF00400	0.672
TRG_ER_diArg_1	27	30	PF00400	0.471
TRG_ER_diArg_1	381	383	PF00400	0.469
TRG_ER_diArg_1	792	795	PF00400	0.648
TRG_ER_diArg_1	835	837	PF00400	0.587
TRG_ER_diArg_1	896	898	PF00400	0.589
TRG_NLS_MonoCore_2	957	962	PF00514	0.721
TRG_NLS_MonoExtC_3	957	963	PF00514	0.693
TRG_Pf-PMV_PEXEL_1	150	155	PF00026	0.443
TRG_Pf-PMV_PEXEL_1	386	391	PF00026	0.266

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I1Z2	Leptomonas seymouri	60%	94%
A0A0S4JHP8	Bodo saltans	43%	100%
A0A3Q8IC06	Leishmania donovani	76%	99%
A4H349	Leishmania braziliensis	22%	100%
A4I0P9	Leishmania infantum	76%	99%
D0A725	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	47%	100%
E9AWQ1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	76%	100%
Q4QAS2	Leishmania major	73%	94%