LeishMANIAdb
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Transcription elongation factor-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Download

Quick info

Protein:
Transcription elongation factor-like protein
Gene product:
transcription elongation factor-like protein
Species:
Leishmania braziliensis
UniProt:
A4HD77_LEIBR
TriTrypDb:
LbrM.24.0190 , LBRM2903_240006600
Length:
133

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HD77
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HD77

Function

Could not find GO biological_process term for this entry.
Molecular functions
Term Name Level Count
GO:0003676 nucleic acid binding 3 2
GO:0003746 translation elongation factor activity 4 2
GO:0005488 binding 1 2
GO:0008135 translation factor activity, RNA binding 3 2
GO:0045182 translation regulator activity 1 2
GO:0090079 translation regulator activity, nucleic acid binding 2 2
GO:0097159 organic cyclic compound binding 2 2
GO:1901363 heterocyclic compound binding 2 2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 66 68 PF00675 0.808
CLV_PCSK_KEX2_1 66 68 PF00082 0.808
CLV_PCSK_SKI1_1 106 110 PF00082 0.719
DOC_USP7_MATH_1 77 81 PF00917 0.805
LIG_14-3-3_CanoR_1 61 69 PF00244 0.808
LIG_Clathr_ClatBox_1 14 18 PF01394 0.793
LIG_FHA_1 84 90 PF00498 0.826
LIG_FHA_2 68 74 PF00498 0.818
LIG_SH2_NCK_1 69 73 PF00017 0.818
LIG_SH2_STAT5 69 72 PF00017 0.813
LIG_SH3_2 93 98 PF14604 0.784
LIG_SH3_3 90 96 PF00018 0.800
LIG_SUMO_SIM_par_1 49 56 PF11976 0.731
MOD_CK1_1 110 116 PF00069 0.758
MOD_CK1_1 27 33 PF00069 0.815
MOD_CK1_1 60 66 PF00069 0.803
MOD_CK1_1 79 85 PF00069 0.484
MOD_CK2_1 22 28 PF00069 0.811
MOD_CK2_1 33 39 PF00069 0.580
MOD_CK2_1 67 73 PF00069 0.815
MOD_GlcNHglycan 32 35 PF01048 0.788
MOD_GlcNHglycan 43 46 PF01048 0.537
MOD_GSK3_1 24 31 PF00069 0.820
MOD_GSK3_1 53 60 PF00069 0.757
MOD_GSK3_1 76 83 PF00069 0.810
MOD_LATS_1 65 71 PF00433 0.814
MOD_NEK2_1 53 58 PF00069 0.746
MOD_PIKK_1 107 113 PF00454 0.727
MOD_PIKK_1 123 129 PF00454 0.459
MOD_PIKK_1 80 86 PF00454 0.821
MOD_PKA_2 60 66 PF00069 0.803
TRG_DiLeu_BaEn_2 7 13 PF01217 0.786

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS