LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein
Species:
Leishmania braziliensis
UniProt:
A4HD52_LEIBR
TriTrypDb:
LbrM.23.1920 , LBRM2903_230030400
Length:
141

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 4
NetGPI no yes: 0, no: 4
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HD52
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HD52

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_KEX2_1 49 51 PF00082 0.511
CLV_PCSK_PC1ET2_1 49 51 PF00082 0.511
CLV_PCSK_SKI1_1 122 126 PF00082 0.542
DOC_USP7_MATH_1 129 133 PF00917 0.564
DOC_USP7_MATH_1 31 35 PF00917 0.715
DOC_USP7_MATH_1 90 94 PF00917 0.831
DOC_WW_Pin1_4 103 108 PF00397 0.737
DOC_WW_Pin1_4 54 59 PF00397 0.590
LIG_14-3-3_CanoR_1 115 120 PF00244 0.662
LIG_14-3-3_CanoR_1 50 58 PF00244 0.550
LIG_BIR_II_1 1 5 PF00653 0.467
LIG_BRCT_BRCA1_1 120 124 PF00533 0.535
LIG_FHA_2 133 139 PF00498 0.566
LIG_FHA_2 82 88 PF00498 0.698
LIG_KLC1_Yacidic_2 11 16 PF13176 0.446
LIG_LIR_Gen_1 2 10 PF02991 0.441
LIG_LIR_Nem_3 121 127 PF02991 0.543
LIG_LIR_Nem_3 2 7 PF02991 0.486
LIG_SH2_STAP1 40 44 PF00017 0.683
LIG_SH2_STAT5 14 17 PF00017 0.706
LIG_SxIP_EBH_1 48 59 PF03271 0.545
LIG_TRAF2_1 86 89 PF00917 0.593
MOD_CDK_SPK_2 54 59 PF00069 0.579
MOD_CK1_1 102 108 PF00069 0.675
MOD_CK1_1 118 124 PF00069 0.533
MOD_CK1_1 132 138 PF00069 0.512
MOD_CK1_1 54 60 PF00069 0.774
MOD_CK2_1 132 138 PF00069 0.562
MOD_CK2_1 81 87 PF00069 0.600
MOD_CK2_1 90 96 PF00069 0.543
MOD_GlcNHglycan 1 4 PF01048 0.479
MOD_GlcNHglycan 107 110 PF01048 0.577
MOD_GSK3_1 114 121 PF00069 0.557
MOD_GSK3_1 50 57 PF00069 0.556
MOD_GSK3_1 98 105 PF00069 0.700
MOD_N-GLC_1 102 107 PF02516 0.587
MOD_NEK2_1 20 25 PF00069 0.482
MOD_PIKK_1 81 87 PF00454 0.600
MOD_PK_1 115 121 PF00069 0.538
MOD_PKA_2 114 120 PF00069 0.665
MOD_PKA_2 20 26 PF00069 0.606
MOD_ProDKin_1 103 109 PF00069 0.736
MOD_ProDKin_1 54 60 PF00069 0.589
MOD_SUMO_for_1 130 133 PF00179 0.565
MOD_SUMO_rev_2 65 71 PF00179 0.578
TRG_ENDOCYTIC_2 4 7 PF00928 0.596
TRG_ENDOCYTIC_2 40 43 PF00928 0.725

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8IH46 Leishmania donovani 63% 100%
A4I2A9 Leishmania infantum 61% 100%
E9AYF5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 59% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS