ATP-dependent RNA Helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ATP-dependent RNA Helicase

Species:

Leishmania braziliensis

UniProt:

A4HD50_LEIBR

TriTrypDb:

LbrM.23.1900 , LBRM2903_050011200

Length:

972

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005681	spliceosomal complex	3	1
GO:0032991	protein-containing complex	1	1
GO:0071013	catalytic step 2 spliceosome	3	1
GO:0140513	nuclear protein-containing complex	2	1
GO:1902494	catalytic complex	2	1
GO:1990904	ribonucleoprotein complex	2	1

Expansion

Sequence features

A4HD50

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HD50

Function

Biological processes
Term	Name	Level	Count
GO:0000375	RNA splicing, via transesterification reactions	8	1
GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	9	1
GO:0000398	mRNA splicing, via spliceosome	8	1
GO:0006139	nucleobase-containing compound metabolic process	3	1
GO:0006396	RNA processing	6	1
GO:0006397	mRNA processing	7	1
GO:0006725	cellular aromatic compound metabolic process	3	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0008152	metabolic process	1	1
GO:0008380	RNA splicing	7	1
GO:0009987	cellular process	1	1
GO:0016070	RNA metabolic process	5	1
GO:0016071	mRNA metabolic process	6	1
GO:0034641	cellular nitrogen compound metabolic process	3	1
GO:0043170	macromolecule metabolic process	3	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0046483	heterocycle metabolic process	3	1
GO:0071704	organic substance metabolic process	2	1
GO:0090304	nucleic acid metabolic process	4	1
GO:1901360	organic cyclic compound metabolic process	3	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	11
GO:0003676	nucleic acid binding	3	11
GO:0003824	catalytic activity	1	11
GO:0004386	helicase activity	2	11
GO:0005488	binding	1	11
GO:0005524	ATP binding	5	11
GO:0016787	hydrolase activity	2	9
GO:0017076	purine nucleotide binding	4	11
GO:0030554	adenyl nucleotide binding	5	11
GO:0032553	ribonucleotide binding	3	11
GO:0032555	purine ribonucleotide binding	4	11
GO:0032559	adenyl ribonucleotide binding	5	11
GO:0035639	purine ribonucleoside triphosphate binding	4	11
GO:0036094	small molecule binding	2	11
GO:0043167	ion binding	2	11
GO:0043168	anion binding	3	11
GO:0097159	organic cyclic compound binding	2	11
GO:0097367	carbohydrate derivative binding	2	11
GO:0140640	catalytic activity, acting on a nucleic acid	2	11
GO:0140657	ATP-dependent activity	1	11
GO:1901265	nucleoside phosphate binding	3	11
GO:1901363	heterocyclic compound binding	2	11
GO:0003723	RNA binding	4	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	434	438	PF00656	0.473
CLV_C14_Caspase3-7	629	633	PF00656	0.511
CLV_C14_Caspase3-7	742	746	PF00656	0.465
CLV_C14_Caspase3-7	843	847	PF00656	0.751
CLV_C14_Caspase3-7	876	880	PF00656	0.653
CLV_NRD_NRD_1	131	133	PF00675	0.577
CLV_NRD_NRD_1	49	51	PF00675	0.618
CLV_NRD_NRD_1	582	584	PF00675	0.459
CLV_NRD_NRD_1	697	699	PF00675	0.272
CLV_NRD_NRD_1	706	708	PF00675	0.246
CLV_NRD_NRD_1	853	855	PF00675	0.665
CLV_NRD_NRD_1	895	897	PF00675	0.761
CLV_NRD_NRD_1	899	901	PF00675	0.731
CLV_PCSK_FUR_1	580	584	PF00082	0.443
CLV_PCSK_FUR_1	849	853	PF00082	0.672
CLV_PCSK_FUR_1	902	906	PF00082	0.734
CLV_PCSK_KEX2_1	131	133	PF00082	0.583
CLV_PCSK_KEX2_1	49	51	PF00082	0.618
CLV_PCSK_KEX2_1	520	522	PF00082	0.486
CLV_PCSK_KEX2_1	571	573	PF00082	0.650
CLV_PCSK_KEX2_1	582	584	PF00082	0.388
CLV_PCSK_KEX2_1	697	699	PF00082	0.284
CLV_PCSK_KEX2_1	706	708	PF00082	0.257
CLV_PCSK_KEX2_1	851	853	PF00082	0.692
CLV_PCSK_KEX2_1	901	903	PF00082	0.750
CLV_PCSK_KEX2_1	904	906	PF00082	0.731
CLV_PCSK_PC1ET2_1	520	522	PF00082	0.486
CLV_PCSK_PC1ET2_1	571	573	PF00082	0.530
CLV_PCSK_PC1ET2_1	901	903	PF00082	0.748
CLV_PCSK_PC1ET2_1	904	906	PF00082	0.725
CLV_PCSK_PC7_1	849	855	PF00082	0.525
CLV_PCSK_PC7_1	900	906	PF00082	0.749
CLV_PCSK_SKI1_1	143	147	PF00082	0.552
CLV_PCSK_SKI1_1	150	154	PF00082	0.578
CLV_PCSK_SKI1_1	256	260	PF00082	0.370
CLV_PCSK_SKI1_1	426	430	PF00082	0.246
CLV_PCSK_SKI1_1	52	56	PF00082	0.436
CLV_PCSK_SKI1_1	595	599	PF00082	0.284
CLV_PCSK_SKI1_1	709	713	PF00082	0.255
CLV_PCSK_SKI1_1	75	79	PF00082	0.658
CLV_PCSK_SKI1_1	805	809	PF00082	0.640
DEG_APCC_DBOX_1	340	348	PF00400	0.498
DEG_APCC_DBOX_1	418	426	PF00400	0.355
DEG_APCC_DBOX_1	51	59	PF00400	0.570
DEG_Nend_UBRbox_3	1	3	PF02207	0.735
DEG_SCF_FBW7_1	105	110	PF00400	0.524
DEG_SCF_FBW7_1	790	797	PF00400	0.504
DEG_SPOP_SBC_1	189	193	PF00917	0.533
DEG_SPOP_SBC_1	400	404	PF00917	0.490
DEG_SPOP_SBC_1	838	842	PF00917	0.641
DOC_CDC14_PxL_1	329	337	PF14671	0.536
DOC_CKS1_1	531	536	PF01111	0.459
DOC_CYCLIN_RxL_1	72	81	PF00134	0.622
DOC_MAPK_DCC_7	341	349	PF00069	0.536
DOC_MAPK_gen_1	196	206	PF00069	0.490
DOC_MAPK_gen_1	706	713	PF00069	0.495
DOC_MAPK_MEF2A_6	199	208	PF00069	0.409
DOC_PP1_RVXF_1	593	600	PF00149	0.402
DOC_PP2B_LxvP_1	208	211	PF13499	0.558
DOC_PP4_MxPP_1	1	4	PF00568	0.477
DOC_USP7_MATH_1	107	111	PF00917	0.737
DOC_USP7_MATH_1	114	118	PF00917	0.725
DOC_USP7_MATH_1	124	128	PF00917	0.679
DOC_USP7_MATH_1	177	181	PF00917	0.468
DOC_USP7_MATH_1	189	193	PF00917	0.477
DOC_USP7_MATH_1	373	377	PF00917	0.546
DOC_USP7_MATH_1	739	743	PF00917	0.512
DOC_USP7_MATH_1	794	798	PF00917	0.626
DOC_USP7_MATH_1	837	841	PF00917	0.662
DOC_USP7_MATH_1	864	868	PF00917	0.815
DOC_USP7_UBL2_3	146	150	PF12436	0.588
DOC_USP7_UBL2_3	897	901	PF12436	0.638
DOC_WW_Pin1_4	101	106	PF00397	0.705
DOC_WW_Pin1_4	159	164	PF00397	0.592
DOC_WW_Pin1_4	231	236	PF00397	0.582
DOC_WW_Pin1_4	530	535	PF00397	0.416
DOC_WW_Pin1_4	673	678	PF00397	0.592
DOC_WW_Pin1_4	68	73	PF00397	0.584
DOC_WW_Pin1_4	790	795	PF00397	0.500
DOC_WW_Pin1_4	91	96	PF00397	0.690
LIG_14-3-3_CanoR_1	100	105	PF00244	0.647
LIG_14-3-3_CanoR_1	256	265	PF00244	0.408
LIG_14-3-3_CanoR_1	341	345	PF00244	0.500
LIG_14-3-3_CanoR_1	419	428	PF00244	0.360
LIG_14-3-3_CanoR_1	464	469	PF00244	0.498
LIG_14-3-3_CanoR_1	502	506	PF00244	0.471
LIG_14-3-3_CanoR_1	536	544	PF00244	0.400
LIG_14-3-3_CanoR_1	595	600	PF00244	0.256
LIG_14-3-3_CanoR_1	697	701	PF00244	0.496
LIG_14-3-3_CanoR_1	902	910	PF00244	0.763
LIG_14-3-3_CanoR_1	918	924	PF00244	0.504
LIG_14-3-3_CterR_2	969	972	PF00244	0.660
LIG_CtBP_PxDLS_1	251	255	PF00389	0.485
LIG_CtBP_PxDLS_1	346	350	PF00389	0.479
LIG_DLG_GKlike_1	464	472	PF00625	0.384
LIG_EH1_1	637	645	PF00400	0.483
LIG_FHA_1	124	130	PF00498	0.641
LIG_FHA_1	162	168	PF00498	0.674
LIG_FHA_1	203	209	PF00498	0.504
LIG_FHA_1	296	302	PF00498	0.592
LIG_FHA_1	352	358	PF00498	0.442
LIG_FHA_1	360	366	PF00498	0.442
LIG_FHA_1	37	43	PF00498	0.495
LIG_FHA_1	387	393	PF00498	0.420
LIG_FHA_1	407	413	PF00498	0.429
LIG_FHA_1	490	496	PF00498	0.492
LIG_FHA_1	506	512	PF00498	0.428
LIG_FHA_1	596	602	PF00498	0.307
LIG_FHA_1	674	680	PF00498	0.492
LIG_FHA_1	712	718	PF00498	0.442
LIG_FHA_1	726	732	PF00498	0.442
LIG_FHA_1	827	833	PF00498	0.649
LIG_FHA_1	92	98	PF00498	0.602
LIG_FHA_2	637	643	PF00498	0.596
LIG_FHA_2	650	656	PF00498	0.382
LIG_FHA_2	808	814	PF00498	0.496
LIG_FHA_2	841	847	PF00498	0.661
LIG_LIR_Apic_2	259	265	PF02991	0.443
LIG_LIR_Apic_2	317	323	PF02991	0.442
LIG_LIR_Gen_1	437	447	PF02991	0.455
LIG_LIR_Gen_1	543	552	PF02991	0.493
LIG_LIR_Gen_1	618	628	PF02991	0.495
LIG_LIR_Gen_1	768	777	PF02991	0.475
LIG_LIR_Gen_1	944	953	PF02991	0.604
LIG_LIR_LC3C_4	728	731	PF02991	0.477
LIG_LIR_Nem_3	192	198	PF02991	0.411
LIG_LIR_Nem_3	437	443	PF02991	0.467
LIG_LIR_Nem_3	5	10	PF02991	0.723
LIG_LIR_Nem_3	526	531	PF02991	0.343
LIG_LIR_Nem_3	543	547	PF02991	0.517
LIG_LIR_Nem_3	598	602	PF02991	0.245
LIG_LIR_Nem_3	618	624	PF02991	0.494
LIG_LIR_Nem_3	636	640	PF02991	0.610
LIG_LIR_Nem_3	768	772	PF02991	0.451
LIG_LIR_Nem_3	944	948	PF02991	0.609
LIG_LIR_Nem_3	964	970	PF02991	0.641
LIG_MYND_1	279	283	PF01753	0.398
LIG_NRBOX	140	146	PF00104	0.515
LIG_NRBOX	456	462	PF00104	0.442
LIG_NRBOX	73	79	PF00104	0.657
LIG_PDZ_Class_2	967	972	PF00595	0.657
LIG_PTB_Apo_2	467	474	PF02174	0.477
LIG_Rb_LxCxE_1	237	259	PF01857	0.424
LIG_Rb_pABgroove_1	819	827	PF01858	0.660
LIG_SH2_CRK	262	266	PF00017	0.517
LIG_SH2_CRK	326	330	PF00017	0.444
LIG_SH2_CRK	440	444	PF00017	0.498
LIG_SH2_CRK	945	949	PF00017	0.552
LIG_SH2_CRK	967	971	PF00017	0.600
LIG_SH2_NCK_1	262	266	PF00017	0.517
LIG_SH2_NCK_1	602	606	PF00017	0.290
LIG_SH2_NCK_1	945	949	PF00017	0.552
LIG_SH2_SRC	630	633	PF00017	0.295
LIG_SH2_STAP1	440	444	PF00017	0.455
LIG_SH2_STAT3	53	56	PF00017	0.655
LIG_SH2_STAT5	10	13	PF00017	0.716
LIG_SH2_STAT5	320	323	PF00017	0.442
LIG_SH2_STAT5	421	424	PF00017	0.427
LIG_SH2_STAT5	522	525	PF00017	0.388
LIG_SH2_STAT5	529	532	PF00017	0.363
LIG_SH2_STAT5	53	56	PF00017	0.595
LIG_SH2_STAT5	630	633	PF00017	0.512
LIG_SH2_STAT5	638	641	PF00017	0.533
LIG_SH2_STAT5	750	753	PF00017	0.442
LIG_SH3_3	133	139	PF00018	0.574
LIG_SH3_3	347	353	PF00018	0.455
LIG_SH3_3	528	534	PF00018	0.363
LIG_SH3_3	641	647	PF00018	0.543
LIG_SH3_3	767	773	PF00018	0.436
LIG_SH3_3	913	919	PF00018	0.558
LIG_SH3_4	897	904	PF00018	0.637
LIG_SUMO_SIM_anti_2	205	210	PF11976	0.538
LIG_SUMO_SIM_anti_2	348	354	PF11976	0.584
LIG_SUMO_SIM_anti_2	683	691	PF11976	0.457
LIG_SUMO_SIM_par_1	305	312	PF11976	0.498
LIG_SUMO_SIM_par_1	348	354	PF11976	0.442
LIG_TRAF2_1	633	636	PF00917	0.481
LIG_TRAF2_1	784	787	PF00917	0.572
LIG_TYR_ITIM	324	329	PF00017	0.444
LIG_TYR_ITSM	524	531	PF00017	0.336
LIG_UBA3_1	140	146	PF00899	0.514
LIG_UBA3_1	54	61	PF00899	0.431
LIG_WRC_WIRS_1	226	231	PF05994	0.434
LIG_WRC_WIRS_1	920	925	PF05994	0.501
LIG_WW_3	897	901	PF00397	0.825
MOD_CDK_SPK_2	790	795	PF00069	0.500
MOD_CDK_SPxK_1	530	536	PF00069	0.503
MOD_CDK_SPxxK_3	68	75	PF00069	0.665
MOD_CK1_1	156	162	PF00069	0.623
MOD_CK1_1	165	171	PF00069	0.695
MOD_CK1_1	180	186	PF00069	0.363
MOD_CK1_1	188	194	PF00069	0.444
MOD_CK1_1	219	225	PF00069	0.619
MOD_CK1_1	284	290	PF00069	0.455
MOD_CK1_1	314	320	PF00069	0.442
MOD_CK1_1	376	382	PF00069	0.516
MOD_CK1_1	386	392	PF00069	0.575
MOD_CK1_1	690	696	PF00069	0.465
MOD_CK1_1	840	846	PF00069	0.569
MOD_CK1_1	892	898	PF00069	0.576
MOD_CK1_1	906	912	PF00069	0.663
MOD_CK1_1	962	968	PF00069	0.621
MOD_CK2_1	649	655	PF00069	0.557
MOD_CK2_1	690	696	PF00069	0.477
MOD_Cter_Amidation	849	852	PF01082	0.690
MOD_GlcNHglycan	110	113	PF01048	0.656
MOD_GlcNHglycan	116	119	PF01048	0.602
MOD_GlcNHglycan	126	129	PF01048	0.692
MOD_GlcNHglycan	153	156	PF01048	0.666
MOD_GlcNHglycan	159	162	PF01048	0.672
MOD_GlcNHglycan	168	171	PF01048	0.677
MOD_GlcNHglycan	17	20	PF01048	0.703
MOD_GlcNHglycan	187	190	PF01048	0.518
MOD_GlcNHglycan	217	221	PF01048	0.655
MOD_GlcNHglycan	283	286	PF01048	0.574
MOD_GlcNHglycan	289	292	PF01048	0.613
MOD_GlcNHglycan	313	316	PF01048	0.242
MOD_GlcNHglycan	380	383	PF01048	0.327
MOD_GlcNHglycan	403	406	PF01048	0.722
MOD_GlcNHglycan	44	47	PF01048	0.584
MOD_GlcNHglycan	66	69	PF01048	0.628
MOD_GlcNHglycan	876	879	PF01048	0.519
MOD_GlcNHglycan	884	887	PF01048	0.504
MOD_GlcNHglycan	961	964	PF01048	0.584
MOD_GSK3_1	103	110	PF00069	0.732
MOD_GSK3_1	114	121	PF00069	0.521
MOD_GSK3_1	153	160	PF00069	0.620
MOD_GSK3_1	161	168	PF00069	0.598
MOD_GSK3_1	185	192	PF00069	0.530
MOD_GSK3_1	209	216	PF00069	0.652
MOD_GSK3_1	225	232	PF00069	0.535
MOD_GSK3_1	283	290	PF00069	0.642
MOD_GSK3_1	373	380	PF00069	0.528
MOD_GSK3_1	501	508	PF00069	0.447
MOD_GSK3_1	536	543	PF00069	0.498
MOD_GSK3_1	64	71	PF00069	0.635
MOD_GSK3_1	737	744	PF00069	0.463
MOD_GSK3_1	790	797	PF00069	0.605
MOD_GSK3_1	84	91	PF00069	0.475
MOD_GSK3_1	852	859	PF00069	0.774
MOD_GSK3_1	874	881	PF00069	0.698
MOD_GSK3_1	95	102	PF00069	0.746
MOD_N-GLC_1	400	405	PF02516	0.614
MOD_N-GLC_1	680	685	PF02516	0.487
MOD_N-GLC_1	873	878	PF02516	0.736
MOD_N-GLC_1	892	897	PF02516	0.807
MOD_NEK2_1	153	158	PF00069	0.639
MOD_NEK2_1	190	195	PF00069	0.469
MOD_NEK2_1	229	234	PF00069	0.617
MOD_NEK2_1	42	47	PF00069	0.572
MOD_NEK2_1	507	512	PF00069	0.444
MOD_NEK2_1	523	528	PF00069	0.420
MOD_NEK2_1	666	671	PF00069	0.467
MOD_NEK2_1	961	966	PF00069	0.563
MOD_PIKK_1	180	186	PF00454	0.561
MOD_PIKK_1	209	215	PF00454	0.496
MOD_PIKK_1	383	389	PF00454	0.496
MOD_PIKK_1	690	696	PF00454	0.453
MOD_PIKK_1	962	968	PF00454	0.596
MOD_PK_1	536	542	PF00069	0.531
MOD_PKA_1	852	858	PF00069	0.515
MOD_PKA_2	340	346	PF00069	0.537
MOD_PKA_2	489	495	PF00069	0.476
MOD_PKA_2	501	507	PF00069	0.413
MOD_PKA_2	535	541	PF00069	0.466
MOD_PKA_2	696	702	PF00069	0.544
MOD_PKA_2	852	858	PF00069	0.739
MOD_PKA_2	941	947	PF00069	0.587
MOD_PKA_2	99	105	PF00069	0.630
MOD_Plk_1	680	686	PF00069	0.353
MOD_Plk_1	906	912	PF00069	0.498
MOD_Plk_2-3	636	642	PF00069	0.482
MOD_Plk_2-3	649	655	PF00069	0.559
MOD_Plk_2-3	856	862	PF00069	0.719
MOD_Plk_4	225	231	PF00069	0.663
MOD_Plk_4	345	351	PF00069	0.584
MOD_Plk_4	361	367	PF00069	0.429
MOD_Plk_4	501	507	PF00069	0.481
MOD_Plk_4	595	601	PF00069	0.264
MOD_Plk_4	725	731	PF00069	0.496
MOD_Plk_4	765	771	PF00069	0.287
MOD_ProDKin_1	101	107	PF00069	0.705
MOD_ProDKin_1	159	165	PF00069	0.592
MOD_ProDKin_1	231	237	PF00069	0.580
MOD_ProDKin_1	530	536	PF00069	0.426
MOD_ProDKin_1	673	679	PF00069	0.577
MOD_ProDKin_1	68	74	PF00069	0.581
MOD_ProDKin_1	790	796	PF00069	0.504
MOD_ProDKin_1	91	97	PF00069	0.690
TRG_DiLeu_BaEn_1	696	701	PF01217	0.473
TRG_DiLeu_BaLyEn_6	136	141	PF01217	0.543
TRG_DiLeu_BaLyEn_6	320	325	PF01217	0.455
TRG_DiLeu_BaLyEn_6	38	43	PF01217	0.624
TRG_DiLeu_BaLyEn_6	461	466	PF01217	0.473
TRG_DiLeu_BaLyEn_6	583	588	PF01217	0.485
TRG_ENDOCYTIC_2	326	329	PF00928	0.444
TRG_ENDOCYTIC_2	440	443	PF00928	0.455
TRG_ENDOCYTIC_2	528	531	PF00928	0.388
TRG_ENDOCYTIC_2	637	640	PF00928	0.560
TRG_ENDOCYTIC_2	945	948	PF00928	0.602
TRG_ENDOCYTIC_2	967	970	PF00928	0.594
TRG_ER_diArg_1	48	50	PF00400	0.672
TRG_ER_diArg_1	580	583	PF00400	0.600
TRG_ER_diArg_1	706	709	PF00400	0.481
TRG_ER_diArg_1	849	852	PF00400	0.674
TRG_ER_diArg_1	899	902	PF00400	0.744
TRG_NLS_MonoExtC_3	899	904	PF00514	0.727
TRG_NLS_MonoExtN_4	897	904	PF00514	0.749
TRG_Pf-PMV_PEXEL_1	143	147	PF00026	0.580
TRG_Pf-PMV_PEXEL_1	355	359	PF00026	0.242
TRG_Pf-PMV_PEXEL_1	481	485	PF00026	0.271
TRG_Pf-PMV_PEXEL_1	52	56	PF00026	0.412
TRG_Pf-PMV_PEXEL_1	698	703	PF00026	0.273

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I0W3	Leptomonas seymouri	55%	100%
A0A0S4IKX9	Bodo saltans	35%	100%
A0A1X0NJY6	Trypanosomatidae	40%	100%
A0A3S5IQZ7	Trypanosoma rangeli	47%	100%
A0A3S7WP45	Leishmania donovani	76%	97%
A4HSI1	Leishmania infantum	76%	97%
C9ZUC4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	96%
E9AKG5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	77%	98%
Q4QJE3	Leishmania major	77%	100%