Retrotransposon hot spot (RHS) protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania braziliensis

UniProt:

A4HD28_LEIBR

TriTrypDb:

LbrM.23.1680

Length:

224

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

A4HD28

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HD28

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	117	119	PF00675	0.817
CLV_NRD_NRD_1	149	151	PF00675	0.594
CLV_NRD_NRD_1	183	185	PF00675	0.618
CLV_NRD_NRD_1	19	21	PF00675	0.598
CLV_NRD_NRD_1	209	211	PF00675	0.584
CLV_PCSK_FUR_1	147	151	PF00082	0.595
CLV_PCSK_KEX2_1	10	12	PF00082	0.604
CLV_PCSK_KEX2_1	117	119	PF00082	0.817
CLV_PCSK_KEX2_1	149	151	PF00082	0.594
CLV_PCSK_KEX2_1	18	20	PF00082	0.495
CLV_PCSK_KEX2_1	182	184	PF00082	0.616
CLV_PCSK_KEX2_1	209	211	PF00082	0.584
CLV_PCSK_PC1ET2_1	10	12	PF00082	0.604
CLV_PCSK_PC1ET2_1	18	20	PF00082	0.495
CLV_PCSK_SKI1_1	153	157	PF00082	0.598
CLV_PCSK_SKI1_1	32	36	PF00082	0.580
DEG_APCC_DBOX_1	152	160	PF00400	0.795
DEG_Nend_UBRbox_2	1	3	PF02207	0.819
DOC_CKS1_1	62	67	PF01111	0.798
DOC_MAPK_gen_1	149	159	PF00069	0.794
DOC_MAPK_MEF2A_6	192	200	PF00069	0.809
DOC_MAPK_MEF2A_6	55	63	PF00069	0.830
DOC_USP7_MATH_1	166	170	PF00917	0.780
DOC_USP7_MATH_1	177	181	PF00917	0.656
DOC_WW_Pin1_4	61	66	PF00397	0.805
LIG_14-3-3_CanoR_1	110	119	PF00244	0.607
LIG_14-3-3_CanoR_1	165	175	PF00244	0.786
LIG_14-3-3_CanoR_1	209	213	PF00244	0.784
LIG_14-3-3_CanoR_1	69	77	PF00244	0.761
LIG_Actin_WH2_2	193	211	PF00022	0.793
LIG_FHA_1	100	106	PF00498	0.704
LIG_FHA_1	69	75	PF00498	0.766
LIG_FHA_2	10	16	PF00498	0.793
LIG_LIR_Gen_1	211	218	PF02991	0.786
LIG_LIR_Gen_1	98	105	PF02991	0.692
LIG_LIR_Nem_3	211	215	PF02991	0.783
LIG_LIR_Nem_3	98	103	PF02991	0.549
LIG_NRBOX	199	205	PF00104	0.794
LIG_NRBOX	83	89	PF00104	0.549
LIG_SH2_SRC	40	43	PF00017	0.807
LIG_SH2_STAP1	40	44	PF00017	0.806
LIG_SH3_3	154	160	PF00018	0.796
LIG_SUMO_SIM_anti_2	57	64	PF11976	0.824
LIG_SUMO_SIM_anti_2	85	91	PF11976	0.549
LIG_SUMO_SIM_par_1	79	85	PF11976	0.549
LIG_SUMO_SIM_par_1	93	98	PF11976	0.305
MOD_GlcNHglycan	125	128	PF01048	0.549
MOD_GlcNHglycan	137	140	PF01048	0.339
MOD_GlcNHglycan	168	171	PF01048	0.581
MOD_GlcNHglycan	49	52	PF01048	0.637
MOD_GlcNHglycan	97	100	PF01048	0.549
MOD_GSK3_1	57	64	PF00069	0.824
MOD_GSK3_1	95	102	PF00069	0.549
MOD_NEK2_1	171	176	PF00069	0.790
MOD_NEK2_1	203	208	PF00069	0.780
MOD_PKA_1	149	155	PF00069	0.790
MOD_PKA_2	149	155	PF00069	0.790
MOD_PKA_2	208	214	PF00069	0.784
MOD_PKA_2	47	53	PF00069	0.835
MOD_PKA_2	68	74	PF00069	0.770
MOD_PKB_1	147	155	PF00069	0.792
MOD_Plk_1	120	126	PF00069	0.606
MOD_Plk_1	57	63	PF00069	0.827
MOD_Plk_4	171	177	PF00069	0.790
MOD_Plk_4	203	209	PF00069	0.781
MOD_Plk_4	4	10	PF00069	0.802
MOD_Plk_4	57	63	PF00069	0.827
MOD_Plk_4	82	88	PF00069	0.549
MOD_ProDKin_1	61	67	PF00069	0.801
TRG_DiLeu_BaEn_3	57	63	PF01217	0.827
TRG_ER_diArg_1	117	119	PF00400	0.617
TRG_ER_diArg_1	146	149	PF00400	0.750
TRG_ER_diArg_1	181	184	PF00400	0.811
TRG_ER_diArg_1	208	210	PF00400	0.784
TRG_Pf-PMV_PEXEL_1	117	121	PF00026	0.814