YceI domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

YceI-like domain containing protein, putative

Species:

Leishmania braziliensis

UniProt:

A4HD05_LEIBR

TriTrypDb:

LbrM.23.1440 , LBRM2903_230024700

Length:

186

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HD05

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HD05

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	51	53	PF00675	0.495
CLV_NRD_NRD_1	93	95	PF00675	0.347
CLV_PCSK_KEX2_1	51	53	PF00082	0.547
CLV_PCSK_KEX2_1	7	9	PF00082	0.532
CLV_PCSK_KEX2_1	93	95	PF00082	0.329
CLV_PCSK_PC1ET2_1	7	9	PF00082	0.527
CLV_PCSK_SKI1_1	182	186	PF00082	0.563
CLV_PCSK_SKI1_1	7	11	PF00082	0.391
DEG_Nend_Nbox_1	1	3	PF02207	0.507
DOC_CYCLIN_yCln2_LP_2	34	40	PF00134	0.559
DOC_MAPK_gen_1	77	85	PF00069	0.449
DOC_MAPK_JIP1_4	36	42	PF00069	0.314
DOC_MAPK_MEF2A_6	16	24	PF00069	0.496
DOC_MAPK_MEF2A_6	77	85	PF00069	0.475
DOC_MAPK_RevD_3	38	52	PF00069	0.322
DOC_PP4_FxxP_1	155	158	PF00568	0.362
DOC_USP7_MATH_1	114	118	PF00917	0.591
LIG_14-3-3_CanoR_1	151	159	PF00244	0.546
LIG_14-3-3_CanoR_1	8	18	PF00244	0.486
LIG_14-3-3_CanoR_1	80	86	PF00244	0.446
LIG_14-3-3_CanoR_1	93	99	PF00244	0.417
LIG_APCC_ABBA_1	124	129	PF00400	0.430
LIG_APCC_ABBA_1	20	25	PF00400	0.522
LIG_FHA_1	107	113	PF00498	0.480
LIG_FHA_1	121	127	PF00498	0.362
LIG_FHA_1	170	176	PF00498	0.448
LIG_FHA_1	86	92	PF00498	0.316
LIG_FHA_2	166	172	PF00498	0.575
LIG_LIR_Apic_2	153	158	PF02991	0.405
LIG_LIR_Gen_1	19	29	PF02991	0.512
LIG_LIR_Gen_1	76	86	PF02991	0.506
LIG_LIR_LC3C_4	143	146	PF02991	0.452
LIG_LIR_Nem_3	102	108	PF02991	0.364
LIG_LIR_Nem_3	19	24	PF02991	0.474
LIG_LIR_Nem_3	76	81	PF02991	0.499
LIG_LYPXL_yS_3	105	108	PF13949	0.449
LIG_PDZ_Class_2	181	186	PF00595	0.503
LIG_Pex14_1	163	167	PF04695	0.620
LIG_SH2_PTP2	21	24	PF00017	0.480
LIG_SH2_SRC	21	24	PF00017	0.480
LIG_SH2_STAP1	110	114	PF00017	0.514
LIG_SH2_STAT5	21	24	PF00017	0.370
LIG_SH2_STAT5	98	101	PF00017	0.418
LIG_SH3_3	143	149	PF00018	0.398
LIG_SH3_3	69	75	PF00018	0.519
LIG_SUMO_SIM_par_1	171	177	PF11976	0.447
MOD_CK2_1	73	79	PF00069	0.482
MOD_CK2_1	8	14	PF00069	0.470
MOD_CK2_1	81	87	PF00069	0.426
MOD_GSK3_1	165	172	PF00069	0.526
MOD_GSK3_1	81	88	PF00069	0.512
MOD_N-GLC_1	114	119	PF02516	0.456
MOD_NEK2_1	92	97	PF00069	0.515
MOD_NEK2_2	122	127	PF00069	0.392
MOD_PIKK_1	150	156	PF00454	0.482
MOD_PIKK_1	165	171	PF00454	0.532
MOD_PKA_2	150	156	PF00069	0.525
MOD_PKA_2	92	98	PF00069	0.368
MOD_Plk_4	62	68	PF00069	0.494
MOD_Plk_4	81	87	PF00069	0.401
MOD_SUMO_rev_2	11	18	PF00179	0.527
TRG_DiLeu_BaEn_1	140	145	PF01217	0.413
TRG_DiLeu_BaEn_1	25	30	PF01217	0.599
TRG_DiLeu_BaEn_1	62	67	PF01217	0.277
TRG_DiLeu_BaLyEn_6	103	108	PF01217	0.532
TRG_DiLeu_BaLyEn_6	5	10	PF01217	0.315
TRG_ENDOCYTIC_2	105	108	PF00928	0.426
TRG_ENDOCYTIC_2	21	24	PF00928	0.476
TRG_ER_diArg_1	92	94	PF00400	0.383
TRG_NES_CRM1_1	14	25	PF08389	0.502

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I2D1	Leptomonas seymouri	75%	100%
A0A0S4ITC1	Bodo saltans	44%	97%
A0A1X0NXE1	Trypanosomatidae	53%	99%
A0A3Q8IBN7	Leishmania donovani	89%	98%
A0A3R7LAA8	Trypanosoma rangeli	53%	100%
A4I0J0	Leishmania infantum	89%	98%
C9ZVB6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	49%	95%
E9AWF2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	98%
Q4QB20	Leishmania major	87%	100%