Exonuclease 1

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Exonuclease 1

Gene product:

XPG N-terminal domain/XPG I-region, putative

Species:

Leishmania braziliensis

UniProt:

A4HD00_LEIBR

TriTrypDb:

LbrM.23.1390 , LBRM2903_230024100

Length:

1009

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	6
GO:0043226	organelle	2	6
GO:0043227	membrane-bounded organelle	3	6
GO:0043229	intracellular organelle	3	6
GO:0043231	intracellular membrane-bounded organelle	4	6
GO:0110165	cellular anatomical entity	1	6

Expansion

Sequence features

A4HD00

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HD00

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	6
GO:0006259	DNA metabolic process	4	6
GO:0006281	DNA repair	5	6
GO:0006725	cellular aromatic compound metabolic process	3	6
GO:0006807	nitrogen compound metabolic process	2	6
GO:0006950	response to stress	2	6
GO:0006974	DNA damage response	4	6
GO:0008152	metabolic process	1	6
GO:0009987	cellular process	1	6
GO:0033554	cellular response to stress	3	6
GO:0034641	cellular nitrogen compound metabolic process	3	6
GO:0043170	macromolecule metabolic process	3	6
GO:0044237	cellular metabolic process	2	6
GO:0044238	primary metabolic process	2	6
GO:0044260	obsolete cellular macromolecule metabolic process	3	6
GO:0046483	heterocycle metabolic process	3	6
GO:0050896	response to stimulus	1	6
GO:0051716	cellular response to stimulus	2	6
GO:0071704	organic substance metabolic process	2	6
GO:0090304	nucleic acid metabolic process	4	6
GO:1901360	organic cyclic compound metabolic process	3	6

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	6
GO:0003677	DNA binding	4	6
GO:0003824	catalytic activity	1	6
GO:0004518	nuclease activity	4	6
GO:0004527	exonuclease activity	5	6
GO:0004529	DNA exonuclease activity	5	6
GO:0004536	DNA nuclease activity	4	6
GO:0005488	binding	1	6
GO:0008409	5'-3' exonuclease activity	6	6
GO:0016787	hydrolase activity	2	6
GO:0016788	hydrolase activity, acting on ester bonds	3	6
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	6	6
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	6	6
GO:0035312	5'-3' DNA exonuclease activity	7	6
GO:0043167	ion binding	2	6
GO:0043169	cation binding	3	6
GO:0046872	metal ion binding	4	6
GO:0097159	organic cyclic compound binding	2	6
GO:0140097	catalytic activity, acting on DNA	3	6
GO:0140640	catalytic activity, acting on a nucleic acid	2	6
GO:1901363	heterocyclic compound binding	2	6
GO:0004519	endonuclease activity	5	1
GO:0004520	DNA endonuclease activity	5	1
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	6	1
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	6	1
GO:0017108	5'-flap endonuclease activity	7	1
GO:0048256	flap endonuclease activity	6	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	168	172	PF00656	0.495
CLV_C14_Caspase3-7	610	614	PF00656	0.776
CLV_C14_Caspase3-7	65	69	PF00656	0.761
CLV_NRD_NRD_1	139	141	PF00675	0.341
CLV_NRD_NRD_1	161	163	PF00675	0.566
CLV_NRD_NRD_1	280	282	PF00675	0.521
CLV_NRD_NRD_1	304	306	PF00675	0.736
CLV_NRD_NRD_1	420	422	PF00675	0.487
CLV_NRD_NRD_1	510	512	PF00675	0.565
CLV_NRD_NRD_1	657	659	PF00675	0.532
CLV_NRD_NRD_1	773	775	PF00675	0.620
CLV_NRD_NRD_1	782	784	PF00675	0.669
CLV_PCSK_FUR_1	136	140	PF00082	0.341
CLV_PCSK_FUR_1	159	163	PF00082	0.459
CLV_PCSK_FUR_1	508	512	PF00082	0.555
CLV_PCSK_KEX2_1	138	140	PF00082	0.341
CLV_PCSK_KEX2_1	159	161	PF00082	0.532
CLV_PCSK_KEX2_1	280	282	PF00082	0.521
CLV_PCSK_KEX2_1	304	306	PF00082	0.736
CLV_PCSK_KEX2_1	420	422	PF00082	0.487
CLV_PCSK_KEX2_1	510	512	PF00082	0.565
CLV_PCSK_KEX2_1	657	659	PF00082	0.532
CLV_PCSK_KEX2_1	773	775	PF00082	0.581
CLV_PCSK_SKI1_1	174	178	PF00082	0.466
CLV_PCSK_SKI1_1	298	302	PF00082	0.650
CLV_PCSK_SKI1_1	389	393	PF00082	0.461
DEG_Kelch_Keap1_1	617	622	PF01344	0.579
DEG_SPOP_SBC_1	287	291	PF00917	0.450
DEG_SPOP_SBC_1	575	579	PF00917	0.689
DOC_CKS1_1	930	935	PF01111	0.544
DOC_CKS1_1	989	994	PF01111	0.523
DOC_CYCLIN_yCln2_LP_2	269	275	PF00134	0.455
DOC_MAPK_DCC_7	112	120	PF00069	0.541
DOC_MAPK_FxFP_2	412	415	PF00069	0.492
DOC_MAPK_gen_1	23	33	PF00069	0.541
DOC_MAPK_gen_1	44	53	PF00069	0.471
DOC_MAPK_MEF2A_6	112	120	PF00069	0.541
DOC_MAPK_MEF2A_6	23	31	PF00069	0.541
DOC_PP2B_LxvP_1	269	272	PF13499	0.454
DOC_PP2B_LxvP_1	273	276	PF13499	0.419
DOC_PP4_FxxP_1	412	415	PF00568	0.492
DOC_PP4_FxxP_1	554	557	PF00568	0.647
DOC_PP4_FxxP_1	909	912	PF00568	0.684
DOC_SPAK_OSR1_1	112	116	PF12202	0.541
DOC_USP7_MATH_1	239	243	PF00917	0.541
DOC_USP7_MATH_1	331	335	PF00917	0.626
DOC_USP7_MATH_1	550	554	PF00917	0.523
DOC_USP7_MATH_1	575	579	PF00917	0.689
DOC_USP7_MATH_1	651	655	PF00917	0.615
DOC_USP7_MATH_1	707	711	PF00917	0.544
DOC_USP7_MATH_1	736	740	PF00917	0.668
DOC_USP7_MATH_1	868	872	PF00917	0.660
DOC_USP7_MATH_1	896	900	PF00917	0.523
DOC_USP7_MATH_1	916	920	PF00917	0.603
DOC_USP7_MATH_1	926	930	PF00917	0.569
DOC_USP7_UBL2_3	1003	1007	PF12436	0.664
DOC_USP7_UBL2_3	389	393	PF12436	0.461
DOC_WW_Pin1_4	437	442	PF00397	0.430
DOC_WW_Pin1_4	647	652	PF00397	0.638
DOC_WW_Pin1_4	658	663	PF00397	0.618
DOC_WW_Pin1_4	78	83	PF00397	0.566
DOC_WW_Pin1_4	819	824	PF00397	0.589
DOC_WW_Pin1_4	879	884	PF00397	0.688
DOC_WW_Pin1_4	892	897	PF00397	0.566
DOC_WW_Pin1_4	929	934	PF00397	0.671
DOC_WW_Pin1_4	971	976	PF00397	0.661
DOC_WW_Pin1_4	988	993	PF00397	0.495
LIG_14-3-3_CanoR_1	286	296	PF00244	0.552
LIG_14-3-3_CanoR_1	326	335	PF00244	0.563
LIG_14-3-3_CanoR_1	402	412	PF00244	0.480
LIG_14-3-3_CanoR_1	44	53	PF00244	0.471
LIG_14-3-3_CanoR_1	510	519	PF00244	0.610
LIG_14-3-3_CanoR_1	598	607	PF00244	0.666
LIG_14-3-3_CanoR_1	649	659	PF00244	0.557
LIG_14-3-3_CanoR_1	724	729	PF00244	0.535
LIG_14-3-3_CanoR_1	746	752	PF00244	0.527
LIG_14-3-3_CanoR_1	837	842	PF00244	0.582
LIG_14-3-3_CanoR_1	849	858	PF00244	0.552
LIG_14-3-3_CanoR_1	869	875	PF00244	0.556
LIG_14-3-3_CanoR_1	913	921	PF00244	0.596
LIG_14-3-3_CanoR_1	950	958	PF00244	0.587
LIG_APCC_ABBA_1	530	535	PF00400	0.667
LIG_APCC_ABBAyCdc20_2	529	535	PF00400	0.667
LIG_BIR_III_4	311	315	PF00653	0.605
LIG_BRCT_BRCA1_1	591	595	PF00533	0.628
LIG_BRCT_BRCA1_1	748	752	PF00533	0.528
LIG_BRCT_BRCA1_1	905	909	PF00533	0.541
LIG_BRCT_BRCA1_1	967	971	PF00533	0.524
LIG_CaM_IQ_9	503	519	PF13499	0.573
LIG_CtBP_PxDLS_1	768	774	PF00389	0.556
LIG_EVH1_1	989	993	PF00568	0.520
LIG_FHA_1	292	298	PF00498	0.491
LIG_FHA_1	441	447	PF00498	0.478
LIG_FHA_1	45	51	PF00498	0.465
LIG_FHA_1	458	464	PF00498	0.582
LIG_FHA_1	488	494	PF00498	0.473
LIG_FHA_1	501	507	PF00498	0.376
LIG_FHA_1	686	692	PF00498	0.666
LIG_FHA_1	74	80	PF00498	0.644
LIG_FHA_1	99	105	PF00498	0.561
LIG_FHA_2	130	136	PF00498	0.624
LIG_FHA_2	147	153	PF00498	0.265
LIG_FHA_2	163	169	PF00498	0.432
LIG_FHA_2	404	410	PF00498	0.520
LIG_FHA_2	610	616	PF00498	0.705
LIG_FHA_2	63	69	PF00498	0.633
LIG_FHA_2	672	678	PF00498	0.543
LIG_Integrin_RGD_1	73	75	PF01839	0.538
LIG_LIR_Apic_2	409	415	PF02991	0.498
LIG_LIR_Apic_2	553	557	PF02991	0.652
LIG_LIR_Apic_2	906	912	PF02991	0.537
LIG_LIR_Gen_1	30	39	PF02991	0.541
LIG_LIR_Gen_1	364	373	PF02991	0.551
LIG_LIR_Gen_1	650	659	PF02991	0.592
LIG_LIR_Gen_1	96	107	PF02991	0.328
LIG_LIR_Nem_3	30	35	PF02991	0.541
LIG_LIR_Nem_3	364	368	PF02991	0.567
LIG_LIR_Nem_3	428	433	PF02991	0.426
LIG_LIR_Nem_3	448	452	PF02991	0.497
LIG_LIR_Nem_3	55	61	PF02991	0.368
LIG_LIR_Nem_3	592	597	PF02991	0.625
LIG_LIR_Nem_3	650	655	PF02991	0.594
LIG_LIR_Nem_3	96	102	PF02991	0.328
LIG_LYPXL_SIV_4	183	191	PF13949	0.458
LIG_MLH1_MIPbox_1	591	595	PF16413	0.628
LIG_OCRL_FandH_1	845	857	PF00620	0.502
LIG_PCNA_PIPBox_1	499	508	PF02747	0.511
LIG_PCNA_yPIPBox_3	495	506	PF02747	0.492
LIG_Pex14_2	842	846	PF04695	0.584
LIG_REV1ctd_RIR_1	276	285	PF16727	0.481
LIG_REV1ctd_RIR_1	51	61	PF16727	0.498
LIG_REV1ctd_RIR_1	592	602	PF16727	0.633
LIG_SH2_CRK	439	443	PF00017	0.453
LIG_SH2_CRK	449	453	PF00017	0.352
LIG_SH2_CRK	494	498	PF00017	0.439
LIG_SH2_CRK	58	62	PF00017	0.399
LIG_SH2_NCK_1	58	62	PF00017	0.399
LIG_SH2_PTP2	32	35	PF00017	0.541
LIG_SH2_SRC	184	187	PF00017	0.481
LIG_SH2_SRC	797	800	PF00017	0.602
LIG_SH2_STAP1	184	188	PF00017	0.481
LIG_SH2_STAP1	222	226	PF00017	0.541
LIG_SH2_STAP1	365	369	PF00017	0.433
LIG_SH2_STAT5	13	16	PF00017	0.541
LIG_SH2_STAT5	155	158	PF00017	0.470
LIG_SH2_STAT5	230	233	PF00017	0.541
LIG_SH2_STAT5	236	239	PF00017	0.499
LIG_SH2_STAT5	251	254	PF00017	0.614
LIG_SH2_STAT5	32	35	PF00017	0.541
LIG_SH2_STAT5	379	382	PF00017	0.486
LIG_SH2_STAT5	431	434	PF00017	0.424
LIG_SH2_STAT5	505	508	PF00017	0.514
LIG_SH2_STAT5	797	800	PF00017	0.550
LIG_SH2_STAT5	904	907	PF00017	0.695
LIG_SH3_3	265	271	PF00018	0.576
LIG_SH3_3	435	441	PF00018	0.418
LIG_SH3_3	494	500	PF00018	0.502
LIG_SH3_3	634	640	PF00018	0.668
LIG_SH3_3	656	662	PF00018	0.621
LIG_SH3_3	818	824	PF00018	0.680
LIG_SH3_3	882	888	PF00018	0.692
LIG_SH3_3	918	924	PF00018	0.615
LIG_SH3_3	984	990	PF00018	0.582
LIG_SUMO_SIM_anti_2	586	592	PF11976	0.474
LIG_SUMO_SIM_anti_2	90	97	PF11976	0.506
LIG_SUMO_SIM_anti_2	945	953	PF11976	0.531
LIG_SUMO_SIM_par_1	100	105	PF11976	0.451
LIG_SUMO_SIM_par_1	586	592	PF11976	0.555
LIG_SUMO_SIM_par_1	663	668	PF11976	0.540
LIG_SUMO_SIM_par_1	85	91	PF11976	0.563
LIG_TRAF2_1	132	135	PF00917	0.541
LIG_TRAF2_1	183	186	PF00917	0.469
LIG_TYR_ITIM	437	442	PF00017	0.430
LIG_TYR_ITIM	447	452	PF00017	0.335
LIG_UBA3_1	1000	1008	PF00899	0.668
LIG_WRC_WIRS_1	259	264	PF05994	0.614
LIG_WRC_WIRS_1	365	370	PF05994	0.559
LIG_WW_2	921	924	PF00397	0.513
LIG_WW_2	987	990	PF00397	0.623
LIG_WW_3	822	826	PF00397	0.659
LIG_WW_3	910	914	PF00397	0.689
MOD_CDC14_SPxK_1	822	825	PF00782	0.518
MOD_CDK_SPxK_1	819	825	PF00069	0.528
MOD_CDK_SPxxK_3	884	891	PF00069	0.697
MOD_CK1_1	242	248	PF00069	0.541
MOD_CK1_1	440	446	PF00069	0.505
MOD_CK1_1	578	584	PF00069	0.679
MOD_CK1_1	59	65	PF00069	0.458
MOD_CK1_1	620	626	PF00069	0.635
MOD_CK1_1	650	656	PF00069	0.609
MOD_CK1_1	685	691	PF00069	0.593
MOD_CK1_1	69	75	PF00069	0.524
MOD_CK1_1	710	716	PF00069	0.540
MOD_CK1_1	726	732	PF00069	0.549
MOD_CK1_1	739	745	PF00069	0.642
MOD_CK1_1	819	825	PF00069	0.528
MOD_CK1_1	877	883	PF00069	0.660
MOD_CK1_1	884	890	PF00069	0.670
MOD_CK1_1	892	898	PF00069	0.578
MOD_CK1_1	899	905	PF00069	0.537
MOD_CK1_1	929	935	PF00069	0.663
MOD_CK2_1	129	135	PF00069	0.539
MOD_CK2_1	146	152	PF00069	0.424
MOD_CK2_1	346	352	PF00069	0.486
MOD_CK2_1	403	409	PF00069	0.514
MOD_CK2_1	542	548	PF00069	0.542
MOD_CK2_1	605	611	PF00069	0.709
MOD_CK2_1	804	810	PF00069	0.552
MOD_CK2_1	837	843	PF00069	0.581
MOD_CK2_1	849	855	PF00069	0.541
MOD_CK2_1	858	864	PF00069	0.627
MOD_CK2_1	950	956	PF00069	0.669
MOD_DYRK1A_RPxSP_1	658	662	PF00069	0.674
MOD_GlcNHglycan	107	110	PF01048	0.324
MOD_GlcNHglycan	262	265	PF01048	0.341
MOD_GlcNHglycan	298	301	PF01048	0.569
MOD_GlcNHglycan	329	332	PF01048	0.541
MOD_GlcNHglycan	355	358	PF01048	0.602
MOD_GlcNHglycan	374	377	PF01048	0.438
MOD_GlcNHglycan	472	475	PF01048	0.323
MOD_GlcNHglycan	564	567	PF01048	0.671
MOD_GlcNHglycan	570	573	PF01048	0.631
MOD_GlcNHglycan	619	622	PF01048	0.744
MOD_GlcNHglycan	671	674	PF01048	0.680
MOD_GlcNHglycan	677	681	PF01048	0.651
MOD_GlcNHglycan	736	739	PF01048	0.647
MOD_GlcNHglycan	818	821	PF01048	0.548
MOD_GlcNHglycan	870	873	PF01048	0.690
MOD_GlcNHglycan	877	880	PF01048	0.645
MOD_GlcNHglycan	891	894	PF01048	0.515
MOD_GlcNHglycan	901	904	PF01048	0.587
MOD_GlcNHglycan	918	921	PF01048	0.542
MOD_GlcNHglycan	968	971	PF01048	0.576
MOD_GSK3_1	1002	1009	PF00069	0.513
MOD_GSK3_1	254	261	PF00069	0.541
MOD_GSK3_1	282	289	PF00069	0.533
MOD_GSK3_1	327	334	PF00069	0.538
MOD_GSK3_1	57	64	PF00069	0.555
MOD_GSK3_1	574	581	PF00069	0.688
MOD_GSK3_1	605	612	PF00069	0.710
MOD_GSK3_1	643	650	PF00069	0.653
MOD_GSK3_1	665	672	PF00069	0.604
MOD_GSK3_1	678	685	PF00069	0.573
MOD_GSK3_1	687	694	PF00069	0.670
MOD_GSK3_1	69	76	PF00069	0.558
MOD_GSK3_1	815	822	PF00069	0.675
MOD_GSK3_1	837	844	PF00069	0.587
MOD_GSK3_1	864	871	PF00069	0.662
MOD_GSK3_1	875	882	PF00069	0.645
MOD_GSK3_1	892	899	PF00069	0.545
MOD_GSK3_1	912	919	PF00069	0.637
MOD_GSK3_1	961	968	PF00069	0.648
MOD_N-GLC_1	700	705	PF02516	0.574
MOD_N-GLC_1	805	810	PF02516	0.551
MOD_NEK2_1	282	287	PF00069	0.517
MOD_NEK2_1	296	301	PF00069	0.509
MOD_NEK2_1	327	332	PF00069	0.534
MOD_NEK2_1	506	511	PF00069	0.536
MOD_NEK2_1	525	530	PF00069	0.468
MOD_NEK2_1	542	547	PF00069	0.523
MOD_NEK2_1	567	572	PF00069	0.687
MOD_NEK2_1	665	670	PF00069	0.694
MOD_NEK2_1	744	749	PF00069	0.530
MOD_NEK2_1	858	863	PF00069	0.564
MOD_NEK2_1	889	894	PF00069	0.700
MOD_NEK2_1	949	954	PF00069	0.630
MOD_NEK2_2	319	324	PF00069	0.492
MOD_NEK2_2	512	517	PF00069	0.617
MOD_PIKK_1	17	23	PF00454	0.541
MOD_PIKK_1	440	446	PF00454	0.469
MOD_PIKK_1	500	506	PF00454	0.502
MOD_PIKK_1	542	548	PF00454	0.693
MOD_PIKK_1	578	584	PF00454	0.664
MOD_PIKK_1	926	932	PF00454	0.548
MOD_PK_1	57	63	PF00069	0.469
MOD_PK_1	837	843	PF00069	0.581
MOD_PKA_1	657	663	PF00069	0.528
MOD_PKA_2	178	184	PF00069	0.484
MOD_PKA_2	285	291	PF00069	0.485
MOD_PKA_2	327	333	PF00069	0.538
MOD_PKA_2	470	476	PF00069	0.332
MOD_PKA_2	657	663	PF00069	0.679
MOD_PKA_2	691	697	PF00069	0.548
MOD_PKA_2	723	729	PF00069	0.533
MOD_PKA_2	745	751	PF00069	0.616
MOD_PKA_2	864	870	PF00069	0.556
MOD_PKA_2	912	918	PF00069	0.701
MOD_PKA_2	949	955	PF00069	0.589
MOD_PKB_1	160	168	PF00069	0.599
MOD_Plk_1	805	811	PF00069	0.554
MOD_Plk_2-3	755	761	PF00069	0.547
MOD_Plk_4	291	297	PF00069	0.498
MOD_Plk_4	364	370	PF00069	0.489
MOD_Plk_4	726	732	PF00069	0.677
MOD_Plk_4	739	745	PF00069	0.536
MOD_Plk_4	747	753	PF00069	0.599
MOD_Plk_4	837	843	PF00069	0.581
MOD_Plk_4	961	967	PF00069	0.642
MOD_Plk_4	98	104	PF00069	0.475
MOD_ProDKin_1	437	443	PF00069	0.440
MOD_ProDKin_1	647	653	PF00069	0.637
MOD_ProDKin_1	658	664	PF00069	0.621
MOD_ProDKin_1	78	84	PF00069	0.551
MOD_ProDKin_1	819	825	PF00069	0.586
MOD_ProDKin_1	879	885	PF00069	0.683
MOD_ProDKin_1	892	898	PF00069	0.563
MOD_ProDKin_1	929	935	PF00069	0.671
MOD_ProDKin_1	971	977	PF00069	0.664
MOD_ProDKin_1	988	994	PF00069	0.497
MOD_SUMO_for_1	209	212	PF00179	0.442
MOD_SUMO_rev_2	456	465	PF00179	0.439
MOD_SUMO_rev_2	616	626	PF00179	0.588
TRG_DiLeu_BaEn_1	186	191	PF01217	0.477
TRG_DiLeu_BaEn_1	243	248	PF01217	0.541
TRG_DiLeu_BaLyEn_6	854	859	PF01217	0.541
TRG_ENDOCYTIC_2	32	35	PF00928	0.541
TRG_ENDOCYTIC_2	365	368	PF00928	0.566
TRG_ENDOCYTIC_2	439	442	PF00928	0.442
TRG_ENDOCYTIC_2	449	452	PF00928	0.343
TRG_ENDOCYTIC_2	494	497	PF00928	0.499
TRG_ENDOCYTIC_2	519	522	PF00928	0.777
TRG_ENDOCYTIC_2	58	61	PF00928	0.389
TRG_ER_diArg_1	136	139	PF00400	0.541
TRG_ER_diArg_1	159	162	PF00400	0.538
TRG_ER_diArg_1	279	281	PF00400	0.563
TRG_ER_diArg_1	419	421	PF00400	0.490
TRG_ER_diArg_1	422	425	PF00400	0.439
TRG_ER_diArg_1	43	46	PF00400	0.464
TRG_ER_diArg_1	508	511	PF00400	0.656
TRG_ER_diArg_1	590	593	PF00400	0.628
TRG_ER_diArg_1	597	600	PF00400	0.572
TRG_ER_diArg_1	657	659	PF00400	0.532
TRG_NES_CRM1_1	723	734	PF08389	0.531
TRG_NLS_MonoExtN_4	556	563	PF00514	0.630

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8ICM3	Leishmania donovani	75%	99%
A4I0I5	Leishmania infantum	74%	99%
E9AWE7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	72%	100%
Q4QB25	Leishmania major	75%	100%