Transmembrane protein 234 homolog

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

Uncharacterised protein family UPF0546, putative

Species:

Leishmania braziliensis

UniProt:

A4HCY9_LEIBR

TriTrypDb:

LbrM.23.1280 , LBRM2903_230022700

Length:

121


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	9
GO:0110165	cellular anatomical entity	1	9

A4HCY9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HCY9


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	41	43	PF00675	0.257
CLV_PCSK_KEX2_1	41	43	PF00082	0.257
CLV_PCSK_SKI1_1	99	103	PF00082	0.211
DEG_Nend_Nbox_1	1	3	PF02207	0.503
DOC_CYCLIN_yClb1_LxF_4	75	81	PF00134	0.243
LIG_Actin_WH2_2	50	66	PF00022	0.267
LIG_Actin_WH2_2	77	94	PF00022	0.258
LIG_BRCT_BRCA1_1	55	59	PF00533	0.243
LIG_BRCT_BRCA1_1	76	80	PF00533	0.279
LIG_DCNL_PONY_1	1	4	PF03556	0.537
LIG_EH1_1	79	87	PF00400	0.302
LIG_FHA_1	100	106	PF00498	0.327
LIG_FHA_1	13	19	PF00498	0.407
LIG_FHA_1	34	40	PF00498	0.355
LIG_FHA_1	46	52	PF00498	0.327
LIG_GBD_Chelix_1	78	86	PF00786	0.267
LIG_NRBOX	2	8	PF00104	0.411
LIG_SH2_STAT5	45	48	PF00017	0.243
LIG_SH3_3	11	17	PF00018	0.457
LIG_SUMO_SIM_par_1	105	111	PF11976	0.302
LIG_UBA3_1	37	44	PF00899	0.355
MOD_CK1_1	28	34	PF00069	0.425
MOD_CK1_1	69	75	PF00069	0.367
MOD_CK2_1	59	65	PF00069	0.312
MOD_GlcNHglycan	117	120	PF01048	0.477
MOD_GlcNHglycan	30	33	PF01048	0.220
MOD_GlcNHglycan	53	56	PF01048	0.302
MOD_GSK3_1	108	115	PF00069	0.361
MOD_GSK3_1	80	87	PF00069	0.241
MOD_N-GLC_1	51	56	PF02516	0.308
MOD_NEK2_1	108	113	PF00069	0.328
MOD_NEK2_1	53	58	PF00069	0.314
MOD_NEK2_1	59	64	PF00069	0.244
MOD_NEK2_1	80	85	PF00069	0.245
MOD_PIKK_1	45	51	PF00454	0.234
MOD_PKA_2	28	34	PF00069	0.380
MOD_Plk_1	33	39	PF00069	0.460
MOD_Plk_1	66	72	PF00069	0.298
MOD_Plk_4	33	39	PF00069	0.396
MOD_Plk_4	53	59	PF00069	0.307
MOD_Plk_4	69	75	PF00069	0.401
MOD_Plk_4	84	90	PF00069	0.254
TRG_DiLeu_BaLyEn_6	14	19	PF01217	0.407
TRG_ER_diArg_1	40	42	PF00400	0.457


Protein	Taxonomy	Sequence identity	Coverage
A0A0S4IWN9	Bodo saltans	60%	100%
A0A1X0NYC0	Trypanosomatidae	64%	96%
A0A3S7WXT4	Leishmania donovani	88%	100%
A0A422N7S4	Trypanosoma rangeli	62%	99%
A0NGI1	Anopheles gambiae	33%	86%
A4I0H4	Leishmania infantum	88%	100%
A7YW81	Bos taurus	33%	86%
C9ZV99	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	62%	100%
Q4QB36	Leishmania major	88%	100%
Q54ZG7	Dictyostelium discoideum	38%	95%
Q8WY98	Homo sapiens	31%	74%