LeishMANIAdb
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Threonine dehydratase

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:
Threonine dehydratase
Gene product:
orthologous HASP
Species:
Leishmania braziliensis
UniProt:
A4HCX2_LEIBR
TriTrypDb:
LbrM.23.1110
Length:
89

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HCX2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HCX2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 48 52 PF00656 0.856
CLV_C14_Caspase3-7 58 62 PF00656 0.691
CLV_PCSK_SKI1_1 7 11 PF00082 0.811
LIG_14-3-3_CanoR_1 11 16 PF00244 0.818
LIG_FHA_1 12 18 PF00498 0.822
MOD_GSK3_1 7 14 PF00069 0.813

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS