LeishMANIAdb
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Cytosolic leucyl aminopeptidase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Cytosolic leucyl aminopeptidase
Gene product:
metallo-peptidase, Clan MF, Family M17
Species:
Leishmania braziliensis
UniProt:
A4HCW4_LEIBR
TriTrypDb:
LbrM.23.1030 , LBRM2903_230018900 *
Length:
455

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
Term Name Level Count
GO:0005737 cytoplasm 2 12
GO:0110165 cellular anatomical entity 1 12
GO:0005856 cytoskeleton 5 1
GO:0030863 cortical cytoskeleton 6 1
GO:0043226 organelle 2 1
GO:0043228 non-membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043232 intracellular non-membrane-bounded organelle 4 1

Expansion

Sequence features

A4HCW4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HCW4

Function

Biological processes
Term Name Level Count
GO:0006508 proteolysis 4 12
GO:0006807 nitrogen compound metabolic process 2 12
GO:0008152 metabolic process 1 12
GO:0019538 protein metabolic process 3 12
GO:0043170 macromolecule metabolic process 3 12
GO:0044238 primary metabolic process 2 12
GO:0071704 organic substance metabolic process 2 12
GO:1901564 organonitrogen compound metabolic process 3 12
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 12
GO:0004177 aminopeptidase activity 5 12
GO:0005488 binding 1 12
GO:0008233 peptidase activity 3 12
GO:0008235 metalloexopeptidase activity 5 12
GO:0008237 metallopeptidase activity 4 12
GO:0008238 exopeptidase activity 4 12
GO:0016787 hydrolase activity 2 12
GO:0030145 manganese ion binding 6 12
GO:0043167 ion binding 2 12
GO:0043169 cation binding 3 12
GO:0046872 metal ion binding 4 12
GO:0046914 transition metal ion binding 5 12
GO:0070006 metalloaminopeptidase activity 6 12
GO:0140096 catalytic activity, acting on a protein 2 12

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 165 167 PF00675 0.417
CLV_NRD_NRD_1 18 20 PF00675 0.454
CLV_NRD_NRD_1 341 343 PF00675 0.312
CLV_NRD_NRD_1 93 95 PF00675 0.715
CLV_PCSK_FUR_1 91 95 PF00082 0.742
CLV_PCSK_KEX2_1 341 343 PF00082 0.330
CLV_PCSK_KEX2_1 87 89 PF00082 0.655
CLV_PCSK_KEX2_1 93 95 PF00082 0.717
CLV_PCSK_PC1ET2_1 87 89 PF00082 0.620
CLV_PCSK_SKI1_1 166 170 PF00082 0.317
CLV_PCSK_SKI1_1 19 23 PF00082 0.490
CLV_PCSK_SKI1_1 215 219 PF00082 0.296
CLV_PCSK_SKI1_1 287 291 PF00082 0.319
CLV_PCSK_SKI1_1 301 305 PF00082 0.246
CLV_PCSK_SKI1_1 59 63 PF00082 0.370
DEG_APCC_DBOX_1 300 308 PF00400 0.417
DEG_COP1_1 142 149 PF00400 0.417
DOC_CYCLIN_yCln2_LP_2 255 261 PF00134 0.296
DOC_MAPK_gen_1 187 197 PF00069 0.309
DOC_MAPK_gen_1 22 31 PF00069 0.340
DOC_MAPK_gen_1 319 327 PF00069 0.301
DOC_MAPK_MEF2A_6 190 197 PF00069 0.331
DOC_MAPK_MEF2A_6 250 259 PF00069 0.296
DOC_PP1_RVXF_1 213 220 PF00149 0.296
DOC_PP2B_LxvP_1 255 258 PF13499 0.296
DOC_PP2B_LxvP_1 31 34 PF13499 0.505
DOC_PP4_FxxP_1 408 411 PF00568 0.417
DOC_USP7_MATH_1 228 232 PF00917 0.296
DOC_USP7_MATH_1 27 31 PF00917 0.515
DOC_USP7_MATH_1 82 86 PF00917 0.462
DOC_USP7_UBL2_3 250 254 PF12436 0.443
DOC_USP7_UBL2_3 377 381 PF12436 0.353
DOC_WW_Pin1_4 101 106 PF00397 0.703
DOC_WW_Pin1_4 344 349 PF00397 0.443
LIG_14-3-3_CanoR_1 205 213 PF00244 0.334
LIG_14-3-3_CanoR_1 50 57 PF00244 0.502
LIG_BIR_III_4 297 301 PF00653 0.296
LIG_Clathr_ClatBox_1 195 199 PF01394 0.312
LIG_CtBP_PxDLS_1 108 112 PF00389 0.587
LIG_EH1_1 440 448 PF00400 0.312
LIG_FHA_1 121 127 PF00498 0.321
LIG_FHA_1 13 19 PF00498 0.385
LIG_FHA_1 207 213 PF00498 0.331
LIG_FHA_1 288 294 PF00498 0.331
LIG_FHA_1 320 326 PF00498 0.336
LIG_FHA_1 329 335 PF00498 0.251
LIG_FHA_1 404 410 PF00498 0.190
LIG_FHA_1 60 66 PF00498 0.332
LIG_FHA_2 228 234 PF00498 0.288
LIG_FHA_2 294 300 PF00498 0.296
LIG_FHA_2 38 44 PF00498 0.536
LIG_FHA_2 4 10 PF00498 0.388
LIG_Integrin_isoDGR_2 203 205 PF01839 0.190
LIG_KLC1_Yacidic_2 148 152 PF13176 0.358
LIG_LIR_Apic_2 365 371 PF02991 0.296
LIG_LIR_Apic_2 406 411 PF02991 0.417
LIG_LIR_Apic_2 42 48 PF02991 0.499
LIG_LIR_Gen_1 192 201 PF02991 0.331
LIG_LIR_Gen_1 412 423 PF02991 0.353
LIG_LIR_LC3C_4 110 113 PF02991 0.566
LIG_LIR_Nem_3 189 194 PF02991 0.333
LIG_LIR_Nem_3 412 418 PF02991 0.353
LIG_Pex14_1 153 157 PF04695 0.417
LIG_Pex14_2 149 153 PF04695 0.353
LIG_Pex14_2 404 408 PF04695 0.296
LIG_SH2_CRK 45 49 PF00017 0.566
LIG_SH2_CRK 71 75 PF00017 0.425
LIG_SH2_NCK_1 433 437 PF00017 0.417
LIG_SH2_PTP2 157 160 PF00017 0.190
LIG_SH2_SRC 157 160 PF00017 0.190
LIG_SH2_SRC 433 436 PF00017 0.417
LIG_SH2_STAT5 150 153 PF00017 0.266
LIG_SH2_STAT5 157 160 PF00017 0.257
LIG_SH2_STAT5 194 197 PF00017 0.301
LIG_SH2_STAT5 200 203 PF00017 0.290
LIG_SH2_STAT5 229 232 PF00017 0.288
LIG_SH2_STAT5 310 313 PF00017 0.353
LIG_SH3_3 102 108 PF00018 0.646
LIG_SH3_3 41 47 PF00018 0.563
LIG_SUMO_SIM_anti_2 290 297 PF11976 0.312
LIG_SUMO_SIM_par_1 322 329 PF11976 0.298
LIG_SUMO_SIM_par_1 334 340 PF11976 0.291
LIG_UBA3_1 282 287 PF00899 0.381
LIG_WRC_WIRS_1 405 410 PF05994 0.190
MOD_CK1_1 206 212 PF00069 0.377
MOD_CK1_1 231 237 PF00069 0.312
MOD_CK1_1 281 287 PF00069 0.312
MOD_CK1_1 337 343 PF00069 0.326
MOD_CK1_1 355 361 PF00069 0.142
MOD_CK2_1 186 192 PF00069 0.353
MOD_CK2_1 227 233 PF00069 0.288
MOD_CK2_1 293 299 PF00069 0.296
MOD_CK2_1 404 410 PF00069 0.268
MOD_GlcNHglycan 206 209 PF01048 0.414
MOD_GSK3_1 203 210 PF00069 0.312
MOD_GSK3_1 227 234 PF00069 0.374
MOD_GSK3_1 241 248 PF00069 0.272
MOD_GSK3_1 273 280 PF00069 0.288
MOD_GSK3_1 344 351 PF00069 0.341
MOD_GSK3_1 352 359 PF00069 0.301
MOD_GSK3_1 59 66 PF00069 0.313
MOD_GSK3_1 82 89 PF00069 0.628
MOD_NEK2_1 12 17 PF00069 0.388
MOD_NEK2_1 352 357 PF00069 0.327
MOD_NEK2_1 387 392 PF00069 0.190
MOD_NEK2_1 404 409 PF00069 0.124
MOD_NEK2_1 63 68 PF00069 0.369
MOD_NEK2_1 74 79 PF00069 0.434
MOD_NEK2_2 245 250 PF00069 0.417
MOD_NEK2_2 27 32 PF00069 0.542
MOD_NEK2_2 3 8 PF00069 0.540
MOD_NMyristoyl 1 7 PF02799 0.313
MOD_PIKK_1 50 56 PF00454 0.450
MOD_PIKK_1 94 100 PF00454 0.511
MOD_PKA_1 319 325 PF00069 0.443
MOD_PKA_1 87 93 PF00069 0.634
MOD_PKA_2 186 192 PF00069 0.400
MOD_PKA_2 204 210 PF00069 0.177
MOD_PKA_2 87 93 PF00069 0.634
MOD_Plk_2-3 37 43 PF00069 0.526
MOD_Plk_4 278 284 PF00069 0.308
MOD_Plk_4 306 312 PF00069 0.285
MOD_Plk_4 352 358 PF00069 0.425
MOD_Plk_4 404 410 PF00069 0.190
MOD_Plk_4 74 80 PF00069 0.336
MOD_ProDKin_1 101 107 PF00069 0.696
MOD_ProDKin_1 344 350 PF00069 0.443
MOD_SUMO_rev_2 374 379 PF00179 0.331
TRG_ENDOCYTIC_2 194 197 PF00928 0.312
TRG_ENDOCYTIC_2 229 232 PF00928 0.331
TRG_ENDOCYTIC_2 314 317 PF00928 0.443
TRG_ENDOCYTIC_2 71 74 PF00928 0.383
TRG_ER_diArg_1 91 94 PF00400 0.740
TRG_NES_CRM1_1 256 269 PF08389 0.353

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P6B6 Leptomonas seymouri 81% 83%
A0A0N0P8E6 Leptomonas seymouri 33% 86%
A0A0N1PAS4 Leptomonas seymouri 34% 85%
A0A0S4IQ79 Bodo saltans 34% 88%
A0A0S4J9X5 Bodo saltans 55% 81%
A0A1X0NWR5 Trypanosomatidae 34% 88%
A0A1X0NWS8 Trypanosomatidae 62% 73%
A0A1X0P4M9 Trypanosomatidae 32% 86%
A0A3R7JY84 Trypanosoma rangeli 33% 88%
A0A3R7MFB6 Trypanosoma rangeli 61% 74%
A0A3S7WXR2 Leishmania donovani 89% 81%
A0A3S7X742 Leishmania donovani 34% 86%
A0K9N9 Burkholderia cenocepacia (strain HI2424) 40% 90%
A0KPF3 Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049) 40% 91%
A0LK12 Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) 38% 90%
A0RKB5 Bacillus thuringiensis (strain Al Hakam) 35% 92%
A0RUA5 Cenarchaeum symbiosum (strain A) 42% 93%
A1BGN2 Chlorobium phaeobacteroides (strain DSM 266) 43% 90%
A1JJ31 Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081) 40% 90%
A1K9L5 Azoarcus sp. (strain BH72) 41% 91%
A1KKQ5 Mycobacterium bovis (strain BCG / Pasteur 1173P2) 39% 88%
A1UIA8 Mycobacterium sp. (strain KMS) 34% 89%
A1V5Z5 Burkholderia mallei (strain SAVP1) 44% 90%
A1VP99 Polaromonas naphthalenivorans (strain CJ2) 37% 89%
A1W776 Acidovorax sp. (strain JS42) 41% 92%
A1WSK3 Verminephrobacter eiseniae (strain EF01-2) 40% 88%
A1WUV1 Halorhodospira halophila (strain DSM 244 / SL1) 39% 91%
A2SAC2 Burkholderia mallei (strain NCTC 10229) 44% 90%
A2SH61 Methylibium petroleiphilum (strain ATCC BAA-1232 / LMG 22953 / PM1) 40% 94%
A3M1A8 Acinetobacter baumannii (strain ATCC 17978 / CIP 53.77 / LMG 1025 / NCDC KC755 / 5377) 38% 94%
A3MLR1 Burkholderia mallei (strain NCTC 10247) 44% 90%
A3N1A7 Actinobacillus pleuropneumoniae serotype 5b (strain L20) 40% 91%
A3N6U4 Burkholderia pseudomallei (strain 668) 44% 90%
A3NSI1 Burkholderia pseudomallei (strain 1106a) 44% 90%
A3Q1S2 Mycobacterium sp. (strain JLS) 34% 89%
A4G7P5 Herminiimonas arsenicoxydans 39% 90%
A4HLW7 Leishmania braziliensis 32% 86%
A4I0E4 Leishmania infantum 89% 81%
A4I996 Leishmania infantum 34% 86%
A4ISE0 Geobacillus thermodenitrificans (strain NG80-2) 37% 92%
A4JGZ2 Burkholderia vietnamiensis (strain G4 / LMG 22486) 44% 90%
A4SSA7 Aeromonas salmonicida (strain A449) 40% 91%
A4TQP6 Yersinia pestis (strain Pestoides F) 40% 90%
A4VNZ7 Pseudomonas stutzeri (strain A1501) 39% 92%
A5CXK2 Vesicomyosocius okutanii subsp. Calyptogena okutanii (strain HA) 38% 95%
A5F5D8 Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395) 41% 90%
A5G9C7 Geotalea uraniireducens (strain Rf4) 42% 92%
A5IAU5 Legionella pneumophila (strain Corby) 39% 94%
A5U4P1 Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) 39% 88%
A5UBH1 Haemophilus influenzae (strain PittEE) 40% 93%
A5UFE2 Haemophilus influenzae (strain PittGG) 40% 93%
A5VPM3 Brucella ovis (strain ATCC 25840 / 63/290 / NCTC 10512) 39% 92%
A5VZ69 Pseudomonas putida (strain ATCC 700007 / DSM 6899 / BCRC 17059 / F1) 36% 92%
A6T0V4 Janthinobacterium sp. (strain Marseille) 36% 90%
A6TWW9 Alkaliphilus metalliredigens (strain QYMF) 33% 91%
A6U7J2 Sinorhizobium medicae (strain WSM419) 38% 92%
A6V0T2 Pseudomonas aeruginosa (strain PA7) 37% 92%
A6VMX3 Actinobacillus succinogenes (strain ATCC 55618 / DSM 22257 / CCUG 43843 / 130Z) 40% 94%
A6X259 Brucella anthropi (strain ATCC 49188 / DSM 6882 / CCUG 24695 / JCM 21032 / LMG 3331 / NBRC 15819 / NCTC 12168 / Alc 37) 39% 91%
A7FML9 Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) 40% 90%
A7GUC8 Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98) 35% 92%
A7IFB7 Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2) 40% 91%
A7MSE5 Vibrio campbellii (strain ATCC BAA-1116) 40% 91%
A7MU37 Vibrio campbellii (strain ATCC BAA-1116) 34% 100%
A7NG41 Roseiflexus castenholzii (strain DSM 13941 / HLO8) 45% 93%
A7Z8B5 Bacillus velezensis (strain DSM 23117 / BGSC 10A6 / LMG 26770 / FZB42) 35% 92%
A8EXL1 Rickettsia canadensis (strain McKiel) 37% 91%
A8F0Q0 Rickettsia massiliae (strain Mtu5) 37% 91%
A8FH04 Bacillus pumilus (strain SAFR-032) 38% 92%
A8G978 Serratia proteamaculans (strain 568) 39% 90%
A8GQW7 Rickettsia rickettsii (strain Sheila Smith) 37% 91%
A8GXC3 Rickettsia bellii (strain OSU 85-389) 41% 91%
A8ML24 Alkaliphilus oremlandii (strain OhILAs) 38% 91%
A9AHG9 Burkholderia multivorans (strain ATCC 17616 / 249) 41% 90%
A9BBV5 Prochlorococcus marinus (strain MIT 9211) 35% 92%
A9IIK3 Bordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448) 40% 91%
A9R5F5 Yersinia pestis bv. Antiqua (strain Angola) 40% 90%
A9VMY8 Bacillus mycoides (strain KBAB4) 35% 92%
A9VXD6 Methylorubrum extorquens (strain PA1) 42% 92%
B0B9F3 Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B) 42% 91%
B0BB32 Chlamydia trachomatis serovar L2b (strain UCH-1/proctitis) 42% 91%
B0BQ37 Actinobacillus pleuropneumoniae serotype 3 (strain JL03) 40% 91%
B0BWB2 Rickettsia rickettsii (strain Iowa) 37% 91%
B0CCF6 Acaryochloris marina (strain MBIC 11017) 36% 92%
B0JL23 Microcystis aeruginosa (strain NIES-843 / IAM M-2473) 39% 93%
B0KQK8 Pseudomonas putida (strain GB-1) 37% 92%
B0RVI0 Xanthomonas campestris pv. campestris (strain B100) 41% 92%
B0U1L5 Xylella fastidiosa (strain M12) 38% 93%
B0UVX4 Histophilus somni (strain 2336) 39% 92%
B0VDC8 Acinetobacter baumannii (strain AYE) 38% 94%
B0VMG3 Acinetobacter baumannii (strain SDF) 38% 94%
B1JBA9 Pseudomonas putida (strain W619) 37% 92%
B1JLS9 Yersinia pseudotuberculosis serotype O:3 (strain YPIII) 40% 90%
B1JWV2 Burkholderia cenocepacia (strain MC0-3) 37% 90%
B1LVC3 Methylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831 / NBRC 15690 / NCIMB 10815 / 0-1) 42% 90%
B1VZN5 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350) 40% 88%
B1WR01 Crocosphaera subtropica (strain ATCC 51142 / BH68) 35% 93%
B1YKV4 Exiguobacterium sibiricum (strain DSM 17290 / CIP 109462 / JCM 13490 / 255-15) 37% 95%
B1YUW5 Burkholderia ambifaria (strain MC40-6) 38% 90%
B1ZAK8 Methylorubrum populi (strain ATCC BAA-705 / NCIMB 13946 / BJ001) 42% 92%
B2FMS4 Stenotrophomonas maltophilia (strain K279a) 42% 93%
B2I1U0 Acinetobacter baumannii (strain ACICU) 38% 94%
B2I6L3 Xylella fastidiosa (strain M23) 38% 93%
B2J3G8 Nostoc punctiforme (strain ATCC 29133 / PCC 73102) 38% 92%
B2JET5 Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 / STM815) 37% 90%
B2K3E9 Yersinia pseudotuberculosis serotype IB (strain PB1/+) 40% 90%
B2SPE7 Xanthomonas oryzae pv. oryzae (strain PXO99A) 40% 93%
B2T146 Paraburkholderia phytofirmans (strain DSM 17436 / LMG 22146 / PsJN) 36% 90%
B2UAK8 Ralstonia pickettii (strain 12J) 38% 91%
B2UTQ8 Helicobacter pylori (strain Shi470) 34% 92%
B2V6F5 Sulfurihydrogenibium sp. (strain YO3AOP1) 33% 90%
B3ED46 Chlorobium limicola (strain DSM 245 / NBRC 103803 / 6330) 40% 90%
B3GXY6 Actinobacillus pleuropneumoniae serotype 7 (strain AP76) 40% 91%
B3PUV3 Rhizobium etli (strain CIAT 652) 38% 92%
B3Q9R8 Rhodopseudomonas palustris (strain TIE-1) 36% 91%
B3QNM5 Chlorobaculum parvum (strain DSM 263 / NCIMB 8327) 39% 90%
B3QVE8 Chloroherpeton thalassium (strain ATCC 35110 / GB-78) 38% 89%
B3R0N4 Phytoplasma mali (strain AT) 38% 91%
B3R663 Cupriavidus taiwanensis (strain DSM 17343 / BCRC 17206 / CCUG 44338 / CIP 107171 / LMG 19424 / R1) 41% 88%
B4E8G9 Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610) 38% 90%
B4F2N1 Proteus mirabilis (strain HI4320) 39% 91%
B4SJ73 Stenotrophomonas maltophilia (strain R551-3) 43% 92%
B5EKZ2 Acidithiobacillus ferrooxidans (strain ATCC 53993 / BNL-5-31) 39% 91%
B5F9Q6 Aliivibrio fischeri (strain MJ11) 38% 91%
B5Z6U1 Helicobacter pylori (strain G27) 34% 92%
B5ZWY7 Rhizobium leguminosarum bv. trifolii (strain WSM2304) 41% 92%
B6EMT2 Aliivibrio salmonicida (strain LFI1238) 38% 91%
B6JLF2 Helicobacter pylori (strain P12) 34% 92%
B7H1P9 Acinetobacter baumannii (strain AB307-0294) 38% 94%
B7HBG1 Bacillus cereus (strain B4264) 35% 92%
B7HUR5 Bacillus cereus (strain AH187) 35% 92%
B7I309 Acinetobacter baumannii (strain AB0057) 38% 94%
B7IMU0 Bacillus cereus (strain G9842) 35% 92%
B7J5I9 Acidithiobacillus ferrooxidans (strain ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455) 39% 91%
B7JDH9 Bacillus cereus (strain AH820) 35% 92%
B7K4A4 Rippkaea orientalis (strain PCC 8801) 37% 93%
B7KCB0 Gloeothece citriformis (strain PCC 7424) 37% 93%
B7KYK4 Methylorubrum extorquens (strain CM4 / NCIMB 13688) 41% 92%
B7UVT6 Pseudomonas aeruginosa (strain LESB58) 38% 92%
B7VJT3 Vibrio atlanticus (strain LGP32) 36% 100%
B8D7Q4 Buchnera aphidicola subsp. Acyrthosiphon pisum (strain Tuc7) 39% 91%
B8D9F2 Buchnera aphidicola subsp. Acyrthosiphon pisum (strain 5A) 39% 91%
B8F6N9 Glaesserella parasuis serovar 5 (strain SH0165) 40% 91%
B8GTX6 Thioalkalivibrio sulfidiphilus (strain HL-EbGR7) 41% 92%
B8HTK3 Cyanothece sp. (strain PCC 7425 / ATCC 29141) 36% 92%
B8J457 Desulfovibrio desulfuricans (strain ATCC 27774 / DSM 6949 / MB) 39% 91%
B9DIX2 Staphylococcus carnosus (strain TM300) 36% 92%
B9J3C5 Bacillus cereus (strain Q1) 35% 92%
B9JCD8 Agrobacterium radiobacter (strain K84 / ATCC BAA-868) 38% 91%
B9JUW1 Agrobacterium vitis (strain S4 / ATCC BAA-846) 40% 92%
B9MJ44 Acidovorax ebreus (strain TPSY) 41% 92%
C0QC86 Desulforapulum autotrophicum (strain ATCC 43914 / DSM 3382 / VKM B-1955 / HRM2) 38% 88%
C0QSL9 Persephonella marina (strain DSM 14350 / EX-H1) 37% 92%
C1A138 Rhodococcus erythropolis (strain PR4 / NBRC 100887) 36% 90%
C1AQC8 Mycobacterium bovis (strain BCG / Tokyo 172 / ATCC 35737 / TMC 1019) 39% 88%
C1AUB5 Rhodococcus opacus (strain B4) 37% 90%
C1DPG2 Azotobacter vinelandii (strain DJ / ATCC BAA-1303) 39% 92%
C1EX85 Bacillus cereus (strain 03BB102) 35% 92%
C1F4B7 Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / BCRC 80197 / JCM 7670 / NBRC 15755 / NCIMB 13165 / 161) 37% 90%
C3K6G5 Pseudomonas fluorescens (strain SBW25) 39% 92%
C3LC57 Bacillus anthracis (strain CDC 684 / NRRL 3495) 35% 92%
C3LR42 Vibrio cholerae serotype O1 (strain M66-2) 41% 90%
C3M9C8 Sinorhizobium fredii (strain NBRC 101917 / NGR234) 40% 92%
C3PDF7 Bacillus anthracis (strain A0248) 35% 92%
C3PMI0 Rickettsia africae (strain ESF-5) 37% 91%
C4K1N6 Rickettsia peacockii (strain Rustic) 36% 91%
C4K346 Hamiltonella defensa subsp. Acyrthosiphon pisum (strain 5AT) 39% 91%
C4LA51 Tolumonas auensis (strain DSM 9187 / TA4) 38% 91%
C5BMG6 Teredinibacter turnerae (strain ATCC 39867 / T7901) 35% 89%
C5CCM4 Micrococcus luteus (strain ATCC 4698 / DSM 20030 / JCM 1464 / NBRC 3333 / NCIMB 9278 / NCTC 2665 / VKM Ac-2230) 33% 89%
C5CLU5 Variovorax paradoxus (strain S110) 40% 89%
C5D720 Geobacillus sp. (strain WCH70) 36% 92%
C6E543 Geobacter sp. (strain M21) 37% 93%
C9ZV91 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 59% 68%
D0A654 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 81%
D0A7H3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 36% 87%
E9ANK8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 34% 85%
E9AWA7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 89% 81%
E9B496 Leishmania mexicana (strain MHOM/GT/2001/U1103) 32% 86%
O06865 Synechococcus elongatus (strain PCC 7942 / FACHB-805) 38% 94%
O25294 Helicobacter pylori (strain ATCC 700392 / 26695) 34% 92%
O32106 Bacillus subtilis (strain 168) 35% 91%
O32956 Mycobacterium leprae (strain TN) 41% 87%
O67868 Aquifex aeolicus (strain VF5) 36% 92%
O68822 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 38% 92%
O84049 Chlamydia trachomatis (strain D/UW-3/Cx) 42% 91%
O86436 Pseudomonas putida 36% 92%
P00727 Bos taurus 34% 88%
P0C6E1 Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) 41% 90%
P27888 Rickettsia prowazekii (strain Madrid E) 41% 91%
P28838 Homo sapiens 34% 88%
P28839 Sus scrofa 34% 88%
P38019 Chlamydia muridarum (strain MoPn / Nigg) 43% 91%
P45334 Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) 39% 93%
P47631 Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37) 37% 100%
P57448 Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) 39% 91%
P57823 Pasteurella multocida (strain Pm70) 40% 92%
P58474 Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) 34% 100%
P73971 Synechocystis sp. (strain PCC 6803 / Kazusa) 36% 92%
P75206 Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1) 39% 100%
P9WHT2 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) 39% 88%
P9WHT3 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) 39% 88%
Q029J4 Solibacter usitatus (strain Ellin6076) 37% 95%
Q02RY8 Pseudomonas aeruginosa (strain UCBPP-PA14) 37% 92%
Q07LG0 Rhodopseudomonas palustris (strain BisA53) 41% 91%
Q086N8 Shewanella frigidimarina (strain NCIMB 400) 40% 91%
Q09735 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 32% 89%
Q0AB75 Alkalilimnicola ehrlichii (strain ATCC BAA-1101 / DSM 17681 / MLHE-1) 35% 92%
Q0AIF5 Nitrosomonas eutropha (strain DSM 101675 / C91 / Nm57) 38% 92%
Q0BCQ2 Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) 38% 90%
Q0I236 Haemophilus somnus (strain 129Pt) 36% 92%
Q0I816 Synechococcus sp. (strain CC9311) 38% 92%
Q0K7F5 Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) 39% 89%
Q0SHL0 Rhodococcus jostii (strain RHA1) 35% 90%
Q0SQ50 Clostridium perfringens (strain SM101 / Type A) 40% 92%
Q0VSA5 Alcanivorax borkumensis (strain ATCC 700651 / DSM 11573 / NCIMB 13689 / SK2) 42% 93%
Q11A96 Trichodesmium erythraeum (strain IMS101) 36% 92%
Q12AW5 Polaromonas sp. (strain JS666 / ATCC BAA-500) 40% 90%
Q12QW7 Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013) 40% 91%
Q143Y9 Paraburkholderia xenovorans (strain LB400) 43% 90%
Q15PX4 Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087) 41% 91%
Q17W06 Helicobacter acinonychis (strain Sheeba) 34% 92%
Q1B6R7 Mycobacterium sp. (strain MCS) 34% 89%
Q1BUE7 Burkholderia cenocepacia (strain AU 1054) 40% 90%
Q1C3R8 Yersinia pestis bv. Antiqua (strain Antiqua) 40% 90%
Q1CM01 Yersinia pestis bv. Antiqua (strain Nepal516) 40% 90%
Q1CTV6 Helicobacter pylori (strain HPAG1) 34% 92%
Q1H4U4 Methylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875) 35% 92%
Q1I5F9 Pseudomonas entomophila (strain L48) 37% 92%
Q1IPU7 Koribacter versatilis (strain Ellin345) 39% 89%
Q1LJJ6 Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34) 39% 89%
Q1MIZ4 Rhizobium leguminosarum bv. viciae (strain 3841) 38% 92%
Q1QTE5 Chromohalobacter salexigens (strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11) 38% 90%
Q1RJN2 Rickettsia bellii (strain RML369-C) 41% 91%
Q21KZ5 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) 39% 91%
Q21WL3 Albidiferax ferrireducens (strain ATCC BAA-621 / DSM 15236 / T118) 38% 95%
Q254B9 Chlamydia felis (strain Fe/C-56) 43% 91%
Q2JKL5 Synechococcus sp. (strain JA-2-3B'a(2-13)) 34% 89%
Q2JRU4 Synechococcus sp. (strain JA-3-3Ab) 41% 89%
Q2KA77 Rhizobium etli (strain CFN 42 / ATCC 51251) 40% 92%
Q2KWX0 Bordetella avium (strain 197N) 39% 90%
Q2NR41 Sodalis glossinidius (strain morsitans) 40% 90%
Q2P7G2 Xanthomonas oryzae pv. oryzae (strain MAFF 311018) 40% 93%
Q2SKR0 Hahella chejuensis (strain KCTC 2396) 39% 92%
Q2T0C0 Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264) 44% 90%
Q2YB18 Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71) 37% 88%
Q315M7 Oleidesulfovibrio alaskensis (strain ATCC BAA-1058 / DSM 17464 / G20) 34% 89%
Q31ET3 Hydrogenovibrio crunogenus (strain DSM 25203 / XCL-2) 37% 92%
Q39DS5 Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383) 38% 90%
Q3A831 Syntrophotalea carbinolica (strain DSM 2380 / NBRC 103641 / GraBd1) 45% 92%
Q3B4B5 Chlorobium luteolum (strain DSM 273 / BCRC 81028 / 2530) 38% 90%
Q3BPA1 Xanthomonas campestris pv. vesicatoria (strain 85-10) 40% 93%
Q3JEC8 Nitrosococcus oceani (strain ATCC 19707 / BCRC 17464 / JCM 30415 / NCIMB 11848 / C-107) 42% 91%
Q3JV16 Burkholderia pseudomallei (strain 1710b) 44% 90%
Q3KHM4 Pseudomonas fluorescens (strain Pf0-1) 37% 92%
Q3KMX6 Chlamydia trachomatis serovar A (strain ATCC VR-571B / DSM 19440 / HAR-13) 42% 91%
Q3M9J6 Trichormus variabilis (strain ATCC 29413 / PCC 7937) 38% 93%
Q3SS04 Nitrobacter winogradskyi (strain ATCC 25391 / DSM 10237 / CIP 104748 / NCIMB 11846 / Nb-255) 40% 91%
Q46XT9 Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) 41% 89%
Q47BG9 Dechloromonas aromatica (strain RCB) 37% 91%
Q488M4 Colwellia psychrerythraea (strain 34H / ATCC BAA-681) 36% 91%
Q4Q3T0 Leishmania major 34% 100%
Q4QJN7 Haemophilus influenzae (strain 86-028NP) 40% 93%
Q4QM33 Haemophilus influenzae (strain 86-028NP) 33% 100%
Q4UKD7 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) 37% 91%
Q4UQP6 Xanthomonas campestris pv. campestris (strain 8004) 41% 92%
Q4ZXH7 Pseudomonas syringae pv. syringae (strain B728a) 37% 92%
Q5E7T8 Aliivibrio fischeri (strain ATCC 700601 / ES114) 38% 91%
Q5FFZ5 Ehrlichia ruminantium (strain Gardel) 41% 91%
Q5H4N2 Xanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85) 40% 93%
Q5HAP2 Ehrlichia ruminantium (strain Welgevonden) 41% 91%
Q5L681 Chlamydia abortus (strain DSM 27085 / S26/3) 43% 91%
Q5N569 Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) 38% 94%
Q5NXM1 Aromatoleum aromaticum (strain EbN1) 41% 91%
Q5QY05 Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR) 40% 91%
Q5V9F0 Dictyostelium discoideum 37% 88%
Q5WTG8 Legionella pneumophila (strain Lens) 38% 94%
Q5X1Q9 Legionella pneumophila (strain Paris) 39% 94%
Q5XGB9 Xenopus tropicalis 37% 88%
Q5YZ53 Nocardia farcinica (strain IFM 10152) 37% 90%
Q606B9 Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath) 38% 92%
Q62LH2 Burkholderia mallei (strain ATCC 23344) 44% 90%
Q632E1 Bacillus cereus (strain ZK / E33L) 35% 92%
Q63WC3 Burkholderia pseudomallei (strain K96243) 44% 90%
Q65FE6 Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46) 36% 92%
Q65SA3 Mannheimia succiniciproducens (strain MBEL55E) 39% 93%
Q66F09 Yersinia pseudotuberculosis serotype I (strain IP32953) 40% 90%
Q67NI4 Symbiobacterium thermophilum (strain T / IAM 14863) 35% 93%
Q68FS4 Rattus norvegicus 34% 88%
Q68XM6 Rickettsia typhi (strain ATCC VR-144 / Wilmington) 41% 91%
Q6A9W5 Cutibacterium acnes (strain DSM 16379 / KPA171202) 37% 90%
Q6FFD8 Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) 40% 94%
Q6HBY2 Bacillus thuringiensis subsp. konkukian (strain 97-27) 35% 92%
Q6LUW0 Photobacterium profundum (strain SS9) 39% 91%
Q6MC72 Protochlamydia amoebophila (strain UWE25) 42% 91%
Q6MH10 Bdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100) 37% 91%
Q6N5B9 Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) 36% 91%
Q6NG90 Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis) 37% 91%
Q72F03 Desulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / NCIMB 8303 / VKM B-1760 / Hildenborough) 35% 90%
Q72UC6 Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130) 40% 92%
Q72YG1 Bacillus cereus (strain ATCC 10987 / NRS 248) 33% 92%
Q73IU2 Wolbachia pipientis wMel 43% 91%
Q73QZ3 Treponema denticola (strain ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104) 35% 96%
Q73YK2 Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10) 38% 88%
Q74GB4 Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA) 42% 92%
Q7KF27 Leishmania major 89% 100%
Q7M8W6 Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W) 33% 94%
Q7MHG4 Vibrio vulnificus (strain YJ016) 40% 91%
Q7MNF5 Vibrio vulnificus (strain YJ016) 33% 100%
Q7NHC6 Gloeobacter violaceus (strain ATCC 29082 / PCC 7421) 38% 90%
Q7NTY9 Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757) 37% 87%
Q7UJ62 Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1) 39% 90%
Q7V0D4 Prochlorococcus marinus subsp. pastoris (strain CCMP1986 / NIES-2087 / MED4) 41% 93%
Q7V5X8 Prochlorococcus marinus (strain MIT 9313) 38% 93%
Q7VAP4 Prochlorococcus marinus (strain SARG / CCMP1375 / SS120) 40% 92%
Q7VEN5 Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) 39% 88%
Q7VGF0 Helicobacter hepaticus (strain ATCC 51449 / 3B1) 34% 96%
Q7VNH9 Haemophilus ducreyi (strain 35000HP / ATCC 700724) 39% 91%
Q7VQT0 Blochmannia floridanus 38% 90%
Q7VW48 Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) 41% 91%
Q7W5K6 Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253) 40% 91%
Q7WD42 Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50) 41% 91%
Q816E3 Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711) 35% 92%
Q81XS5 Bacillus anthracis 35% 92%
Q823J9 Chlamydia caviae (strain ATCC VR-813 / DSM 19441 / 03DC25 / GPIC) 42% 91%
Q82AN2 Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680) 38% 89%
Q82X54 Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298) 38% 92%
Q83G32 Tropheryma whipplei (strain Twist) 35% 91%
Q83I32 Tropheryma whipplei (strain TW08/27) 35% 91%
Q87F32 Xylella fastidiosa (strain Temecula1 / ATCC 700964) 38% 93%
Q87LG8 Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) 40% 91%
Q887M0 Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000) 39% 92%
Q88P73 Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) 36% 92%
Q893F8 Clostridium tetani (strain Massachusetts / E88) 42% 95%
Q89AG2 Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp) 35% 91%
Q89MT4 Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110) 42% 91%
Q8D295 Wigglesworthia glossinidia brevipalpis 36% 91%
Q8DCE5 Vibrio vulnificus (strain CMCP6) 40% 91%
Q8DEZ4 Vibrio vulnificus (strain CMCP6) 33% 100%
Q8DI46 Thermosynechococcus vestitus (strain NIES-2133 / IAM M-273 / BP-1) 40% 92%
Q8EH62 Shewanella oneidensis (strain MR-1) 41% 91%
Q8EI85 Shewanella oneidensis (strain MR-1) 43% 91%
Q8F0Q1 Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601) 40% 92%
Q8FNP8 Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395) 39% 90%
Q8G1M4 Brucella suis biovar 1 (strain 1330) 39% 92%
Q8KD74 Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS) 38% 90%
Q8NNJ4 Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) 39% 91%
Q8PCR4 Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) 41% 92%
Q8PGR0 Xanthomonas axonopodis pv. citri (strain 306) 40% 93%
Q8SQZ7 Encephalitozoon cuniculi (strain GB-M1) 38% 94%
Q8UGC8 Agrobacterium fabrum (strain C58 / ATCC 33970) 38% 92%
Q8XHI3 Clostridium perfringens (strain 13 / Type A) 40% 92%
Q8XWQ8 Ralstonia solanacearum (strain GMI1000) 41% 90%
Q8YG99 Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) 39% 94%
Q8Z064 Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) 38% 93%
Q8ZBH3 Yersinia pestis 40% 90%
Q92J85 Rickettsia conorii (strain ATCC VR-613 / Malish 7) 37% 91%
Q92QY7 Rhizobium meliloti (strain 1021) 37% 92%
Q984S1 Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099) 36% 90%
Q9CM16 Pasteurella multocida (strain Pm70) 35% 100%
Q9CPY7 Mus musculus 34% 88%
Q9JTI8 Neisseria meningitidis serogroup A / serotype 4A (strain DSM 15465 / Z2491) 39% 97%
Q9KTX5 Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) 34% 100%
Q9PH08 Xylella fastidiosa (strain 9a5c) 38% 93%
Q9PP04 Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) 33% 94%
Q9S2Q7 Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) 38% 88%
Q9ZLR1 Helicobacter pylori (strain J99 / ATCC 700824) 34% 92%
V5BNS5 Trypanosoma cruzi 58% 78%
V5BWE3 Trypanosoma cruzi 34% 88%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS