Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania braziliensis

UniProt:

A4HCV6_LEIBR

TriTrypDb:

LbrM.23.0950 , LBRM2903_230018000

Length:

993

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HCV6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HCV6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	608	612	PF00656	0.664
CLV_C14_Caspase3-7	849	853	PF00656	0.672
CLV_NRD_NRD_1	127	129	PF00675	0.685
CLV_NRD_NRD_1	158	160	PF00675	0.666
CLV_NRD_NRD_1	189	191	PF00675	0.675
CLV_NRD_NRD_1	226	228	PF00675	0.785
CLV_NRD_NRD_1	241	243	PF00675	0.566
CLV_NRD_NRD_1	56	58	PF00675	0.678
CLV_NRD_NRD_1	565	567	PF00675	0.722
CLV_NRD_NRD_1	585	587	PF00675	0.445
CLV_NRD_NRD_1	649	651	PF00675	0.729
CLV_NRD_NRD_1	676	678	PF00675	0.722
CLV_NRD_NRD_1	75	77	PF00675	0.504
CLV_NRD_NRD_1	782	784	PF00675	0.759
CLV_NRD_NRD_1	810	812	PF00675	0.677
CLV_NRD_NRD_1	900	902	PF00675	0.786
CLV_NRD_NRD_1	99	101	PF00675	0.687
CLV_PCSK_KEX2_1	189	191	PF00082	0.675
CLV_PCSK_KEX2_1	226	228	PF00082	0.785
CLV_PCSK_KEX2_1	241	243	PF00082	0.566
CLV_PCSK_KEX2_1	247	249	PF00082	0.632
CLV_PCSK_KEX2_1	56	58	PF00082	0.678
CLV_PCSK_KEX2_1	627	629	PF00082	0.740
CLV_PCSK_KEX2_1	648	650	PF00082	0.642
CLV_PCSK_KEX2_1	676	678	PF00082	0.722
CLV_PCSK_KEX2_1	75	77	PF00082	0.504
CLV_PCSK_KEX2_1	782	784	PF00082	0.755
CLV_PCSK_KEX2_1	810	812	PF00082	0.677
CLV_PCSK_KEX2_1	900	902	PF00082	0.786
CLV_PCSK_KEX2_1	965	967	PF00082	0.618
CLV_PCSK_KEX2_1	99	101	PF00082	0.687
CLV_PCSK_PC1ET2_1	247	249	PF00082	0.685
CLV_PCSK_PC1ET2_1	627	629	PF00082	0.657
CLV_PCSK_PC1ET2_1	965	967	PF00082	0.531
CLV_PCSK_PC7_1	644	650	PF00082	0.632
CLV_PCSK_PC7_1	672	678	PF00082	0.718
CLV_PCSK_SKI1_1	190	194	PF00082	0.663
CLV_PCSK_SKI1_1	385	389	PF00082	0.729
CLV_PCSK_SKI1_1	4	8	PF00082	0.661
CLV_PCSK_SKI1_1	811	815	PF00082	0.680
CLV_PCSK_SKI1_1	99	103	PF00082	0.680
DEG_APCC_DBOX_1	445	453	PF00400	0.662
DEG_COP1_1	983	992	PF00400	0.612
DEG_SCF_TRCP1_1	390	396	PF00400	0.684
DEG_SPOP_SBC_1	372	376	PF00917	0.708
DOC_CDC14_PxL_1	918	926	PF14671	0.661
DOC_CKS1_1	191	196	PF01111	0.740
DOC_CKS1_1	924	929	PF01111	0.587
DOC_MAPK_DCC_7	56	66	PF00069	0.665
DOC_MAPK_MEF2A_6	312	320	PF00069	0.676
DOC_MAPK_MEF2A_6	632	639	PF00069	0.533
DOC_MAPK_RevD_3	635	649	PF00069	0.536
DOC_PP1_RVXF_1	674	681	PF00149	0.716
DOC_PP2B_LxvP_1	192	195	PF13499	0.646
DOC_PP2B_LxvP_1	920	923	PF13499	0.669
DOC_PP4_FxxP_1	131	134	PF00568	0.691
DOC_PP4_FxxP_1	305	308	PF00568	0.759
DOC_PP4_FxxP_1	429	432	PF00568	0.782
DOC_USP7_MATH_1	13	17	PF00917	0.726
DOC_USP7_MATH_1	134	138	PF00917	0.758
DOC_USP7_MATH_1	152	156	PF00917	0.553
DOC_USP7_MATH_1	221	225	PF00917	0.632
DOC_USP7_MATH_1	260	264	PF00917	0.760
DOC_USP7_MATH_1	279	283	PF00917	0.526
DOC_USP7_MATH_1	357	361	PF00917	0.694
DOC_USP7_MATH_1	372	376	PF00917	0.576
DOC_USP7_MATH_1	380	384	PF00917	0.631
DOC_USP7_MATH_1	407	411	PF00917	0.645
DOC_USP7_MATH_1	444	448	PF00917	0.673
DOC_USP7_MATH_1	751	755	PF00917	0.697
DOC_USP7_MATH_1	821	825	PF00917	0.741
DOC_USP7_MATH_1	833	837	PF00917	0.738
DOC_USP7_MATH_1	890	894	PF00917	0.710
DOC_USP7_MATH_1	899	903	PF00917	0.643
DOC_WW_Pin1_4	130	135	PF00397	0.727
DOC_WW_Pin1_4	146	151	PF00397	0.518
DOC_WW_Pin1_4	160	165	PF00397	0.532
DOC_WW_Pin1_4	190	195	PF00397	0.743
DOC_WW_Pin1_4	249	254	PF00397	0.777
DOC_WW_Pin1_4	255	260	PF00397	0.682
DOC_WW_Pin1_4	275	280	PF00397	0.608
DOC_WW_Pin1_4	298	303	PF00397	0.769
DOC_WW_Pin1_4	355	360	PF00397	0.774
DOC_WW_Pin1_4	376	381	PF00397	0.702
DOC_WW_Pin1_4	589	594	PF00397	0.658
DOC_WW_Pin1_4	59	64	PF00397	0.723
DOC_WW_Pin1_4	66	71	PF00397	0.653
DOC_WW_Pin1_4	801	806	PF00397	0.686
DOC_WW_Pin1_4	814	819	PF00397	0.606
DOC_WW_Pin1_4	923	928	PF00397	0.599
DOC_WW_Pin1_4	99	104	PF00397	0.680
LIG_14-3-3_CanoR_1	12	19	PF00244	0.766
LIG_14-3-3_CanoR_1	248	253	PF00244	0.705
LIG_14-3-3_CanoR_1	286	293	PF00244	0.686
LIG_14-3-3_CanoR_1	343	350	PF00244	0.768
LIG_14-3-3_CanoR_1	553	561	PF00244	0.640
LIG_14-3-3_CanoR_1	811	820	PF00244	0.744
LIG_14-3-3_CanoR_1	900	904	PF00244	0.780
LIG_14-3-3_CanoR_1	981	990	PF00244	0.674
LIG_Actin_WH2_2	337	353	PF00022	0.681
LIG_AP_GAE_1	757	763	PF02883	0.696
LIG_APCC_ABBA_1	416	421	PF00400	0.769
LIG_APCC_ABBAyCdc20_2	415	421	PF00400	0.769
LIG_BIR_III_4	617	621	PF00653	0.679
LIG_BIR_III_4	850	854	PF00653	0.681
LIG_BRCT_BRCA1_1	147	151	PF00533	0.658
LIG_deltaCOP1_diTrp_1	946	950	PF00928	0.597
LIG_FHA_1	228	234	PF00498	0.700
LIG_FHA_1	23	29	PF00498	0.687
LIG_FHA_1	464	470	PF00498	0.620
LIG_FHA_1	542	548	PF00498	0.771
LIG_FHA_1	552	558	PF00498	0.604
LIG_FHA_1	590	596	PF00498	0.658
LIG_FHA_1	661	667	PF00498	0.738
LIG_FHA_1	924	930	PF00498	0.592
LIG_FHA_2	109	115	PF00498	0.678
LIG_FHA_2	302	308	PF00498	0.675
LIG_FHA_2	453	459	PF00498	0.694
LIG_FHA_2	495	501	PF00498	0.659
LIG_FHA_2	713	719	PF00498	0.677
LIG_FHA_2	732	738	PF00498	0.520
LIG_FHA_2	941	947	PF00498	0.480
LIG_LIR_Apic_2	304	308	PF02991	0.760
LIG_LIR_Apic_2	427	432	PF02991	0.771
LIG_LIR_Gen_1	510	520	PF02991	0.621
LIG_LIR_Gen_1	855	864	PF02991	0.744
LIG_LIR_Nem_3	510	516	PF02991	0.698
LIG_LIR_Nem_3	555	561	PF02991	0.803
LIG_LIR_Nem_3	855	860	PF02991	0.747
LIG_LYPXL_S_1	166	170	PF13949	0.673
LIG_LYPXL_S_1	920	924	PF13949	0.667
LIG_LYPXL_yS_3	167	170	PF13949	0.673
LIG_LYPXL_yS_3	921	924	PF13949	0.667
LIG_MYND_1	164	168	PF01753	0.665
LIG_MYND_1	923	927	PF01753	0.609
LIG_PDZ_Class_1	988	993	PF00595	0.653
LIG_PTAP_UEV_1	252	257	PF05743	0.685
LIG_RPA_C_Fungi	645	657	PF08784	0.639
LIG_SH2_CRK	153	157	PF00017	0.666
LIG_SH2_CRK	513	517	PF00017	0.713
LIG_SH2_CRK	558	562	PF00017	0.713
LIG_SH2_GRB2like	47	50	PF00017	0.691
LIG_SH2_NCK_1	558	562	PF00017	0.713
LIG_SH2_NCK_1	607	611	PF00017	0.666
LIG_SH2_SRC	419	422	PF00017	0.763
LIG_SH2_SRC	47	50	PF00017	0.691
LIG_SH2_SRC	558	561	PF00017	0.715
LIG_SH2_STAT5	191	194	PF00017	0.670
LIG_SH2_STAT5	288	291	PF00017	0.683
LIG_SH2_STAT5	47	50	PF00017	0.691
LIG_SH2_STAT5	575	578	PF00017	0.713
LIG_SH3_2	123	128	PF14604	0.668
LIG_SH3_3	120	126	PF00018	0.758
LIG_SH3_3	158	164	PF00018	0.656
LIG_SH3_3	165	171	PF00018	0.610
LIG_SH3_3	250	256	PF00018	0.771
LIG_SH3_3	270	276	PF00018	0.524
LIG_SH3_3	324	330	PF00018	0.692
LIG_SH3_3	353	359	PF00018	0.772
LIG_SH3_3	363	369	PF00018	0.659
LIG_SH3_3	667	673	PF00018	0.724
LIG_SUMO_SIM_anti_2	482	488	PF11976	0.663
LIG_TRAF2_1	268	271	PF00917	0.715
LIG_TRAF2_1	754	757	PF00917	0.737
LIG_TYR_ITIM	919	924	PF00017	0.675
LIG_WW_3	272	276	PF00397	0.721
LIG_WW_3	897	901	PF00397	0.716
MOD_CDK_SPxxK_3	255	262	PF00069	0.685
MOD_CK1_1	137	143	PF00069	0.711
MOD_CK1_1	146	152	PF00069	0.640
MOD_CK1_1	234	240	PF00069	0.721
MOD_CK1_1	251	257	PF00069	0.619
MOD_CK1_1	301	307	PF00069	0.703
MOD_CK1_1	346	352	PF00069	0.769
MOD_CK1_1	371	377	PF00069	0.747
MOD_CK1_1	383	389	PF00069	0.647
MOD_CK1_1	39	45	PF00069	0.781
MOD_CK1_1	397	403	PF00069	0.552
MOD_CK1_1	409	415	PF00069	0.548
MOD_CK1_1	609	615	PF00069	0.692
MOD_CK1_1	616	622	PF00069	0.669
MOD_CK1_1	633	639	PF00069	0.541
MOD_CK1_1	712	718	PF00069	0.750
MOD_CK1_1	893	899	PF00069	0.826
MOD_CK1_1	90	96	PF00069	0.669
MOD_CK2_1	108	114	PF00069	0.678
MOD_CK2_1	264	270	PF00069	0.707
MOD_CK2_1	301	307	PF00069	0.677
MOD_CK2_1	388	394	PF00069	0.709
MOD_CK2_1	39	45	PF00069	0.781
MOD_CK2_1	712	718	PF00069	0.675
MOD_CK2_1	751	757	PF00069	0.720
MOD_CK2_1	940	946	PF00069	0.580
MOD_Cter_Amidation	187	190	PF01082	0.679
MOD_Cter_Amidation	783	786	PF01082	0.677
MOD_DYRK1A_RPxSP_1	275	279	PF00069	0.781
MOD_GlcNHglycan	136	139	PF01048	0.759
MOD_GlcNHglycan	145	148	PF01048	0.610
MOD_GlcNHglycan	15	18	PF01048	0.712
MOD_GlcNHglycan	206	211	PF01048	0.671
MOD_GlcNHglycan	253	256	PF01048	0.708
MOD_GlcNHglycan	266	269	PF01048	0.681
MOD_GlcNHglycan	322	325	PF01048	0.697
MOD_GlcNHglycan	370	373	PF01048	0.747
MOD_GlcNHglycan	380	383	PF01048	0.631
MOD_GlcNHglycan	390	393	PF01048	0.577
MOD_GlcNHglycan	409	412	PF01048	0.509
MOD_GlcNHglycan	42	45	PF01048	0.715
MOD_GlcNHglycan	426	429	PF01048	0.628
MOD_GlcNHglycan	446	449	PF01048	0.570
MOD_GlcNHglycan	481	484	PF01048	0.676
MOD_GlcNHglycan	50	53	PF01048	0.622
MOD_GlcNHglycan	509	512	PF01048	0.731
MOD_GlcNHglycan	517	520	PF01048	0.705
MOD_GlcNHglycan	561	564	PF01048	0.726
MOD_GlcNHglycan	611	615	PF01048	0.708
MOD_GlcNHglycan	617	621	PF01048	0.688
MOD_GlcNHglycan	622	625	PF01048	0.662
MOD_GlcNHglycan	632	635	PF01048	0.537
MOD_GlcNHglycan	711	714	PF01048	0.755
MOD_GlcNHglycan	723	727	PF01048	0.629
MOD_GlcNHglycan	731	734	PF01048	0.519
MOD_GlcNHglycan	794	797	PF01048	0.776
MOD_GlcNHglycan	8	12	PF01048	0.724
MOD_GlcNHglycan	814	817	PF01048	0.752
MOD_GlcNHglycan	823	826	PF01048	0.640
MOD_GlcNHglycan	868	871	PF01048	0.752
MOD_GlcNHglycan	880	883	PF01048	0.748
MOD_GlcNHglycan	990	993	PF01048	0.741
MOD_GSK3_1	130	137	PF00069	0.752
MOD_GSK3_1	142	149	PF00069	0.574
MOD_GSK3_1	227	234	PF00069	0.701
MOD_GSK3_1	251	258	PF00069	0.733
MOD_GSK3_1	260	267	PF00069	0.713
MOD_GSK3_1	275	282	PF00069	0.587
MOD_GSK3_1	342	349	PF00069	0.768
MOD_GSK3_1	35	42	PF00069	0.785
MOD_GSK3_1	351	358	PF00069	0.656
MOD_GSK3_1	367	374	PF00069	0.566
MOD_GSK3_1	376	383	PF00069	0.651
MOD_GSK3_1	386	393	PF00069	0.599
MOD_GSK3_1	405	412	PF00069	0.505
MOD_GSK3_1	420	427	PF00069	0.560
MOD_GSK3_1	475	482	PF00069	0.730
MOD_GSK3_1	536	543	PF00069	0.756
MOD_GSK3_1	606	613	PF00069	0.726
MOD_GSK3_1	616	623	PF00069	0.744
MOD_GSK3_1	660	667	PF00069	0.736
MOD_GSK3_1	727	734	PF00069	0.688
MOD_GSK3_1	751	758	PF00069	0.839
MOD_GSK3_1	821	828	PF00069	0.817
MOD_GSK3_1	852	859	PF00069	0.684
MOD_GSK3_1	872	879	PF00069	0.792
MOD_GSK3_1	95	102	PF00069	0.764
MOD_GSK3_1	981	988	PF00069	0.571
MOD_LATS_1	284	290	PF00433	0.693
MOD_LATS_1	876	882	PF00433	0.793
MOD_N-GLC_1	19	24	PF02516	0.689
MOD_N-GLC_1	231	236	PF02516	0.707
MOD_N-GLC_1	48	53	PF02516	0.685
MOD_NEK2_1	280	285	PF00069	0.755
MOD_NEK2_1	287	292	PF00069	0.710
MOD_NEK2_1	318	323	PF00069	0.692
MOD_NEK2_1	406	411	PF00069	0.710
MOD_NEK2_1	540	545	PF00069	0.751
MOD_NEK2_1	660	665	PF00069	0.737
MOD_NEK2_1	7	12	PF00069	0.670
MOD_NEK2_1	709	714	PF00069	0.672
MOD_NEK2_1	755	760	PF00069	0.765
MOD_NEK2_2	231	236	PF00069	0.707
MOD_PIKK_1	221	227	PF00454	0.682
MOD_PIKK_1	394	400	PF00454	0.676
MOD_PK_1	606	612	PF00069	0.664
MOD_PKA_2	318	324	PF00069	0.691
MOD_PKA_2	342	348	PF00069	0.769
MOD_PKA_2	39	45	PF00069	0.693
MOD_PKA_2	463	469	PF00069	0.620
MOD_PKA_2	552	558	PF00069	0.735
MOD_PKA_2	721	727	PF00069	0.757
MOD_PKA_2	866	872	PF00069	0.691
MOD_PKA_2	893	899	PF00069	0.800
MOD_PKA_2	90	96	PF00069	0.717
MOD_PKA_2	968	974	PF00069	0.502
MOD_PKA_2	980	986	PF00069	0.531
MOD_PKB_1	262	270	PF00069	0.798
MOD_Plk_1	22	28	PF00069	0.687
MOD_Plk_1	231	237	PF00069	0.793
MOD_Plk_1	744	750	PF00069	0.783
MOD_Plk_1	755	761	PF00069	0.641
MOD_Plk_1	833	839	PF00069	0.753
MOD_Plk_2-3	108	114	PF00069	0.678
MOD_Plk_2-3	756	762	PF00069	0.697
MOD_Plk_4	301	307	PF00069	0.764
MOD_Plk_4	536	542	PF00069	0.757
MOD_Plk_4	575	581	PF00069	0.619
MOD_Plk_4	968	974	PF00069	0.467
MOD_ProDKin_1	130	136	PF00069	0.729
MOD_ProDKin_1	146	152	PF00069	0.517
MOD_ProDKin_1	160	166	PF00069	0.535
MOD_ProDKin_1	190	196	PF00069	0.744
MOD_ProDKin_1	249	255	PF00069	0.777
MOD_ProDKin_1	275	281	PF00069	0.783
MOD_ProDKin_1	298	304	PF00069	0.768
MOD_ProDKin_1	355	361	PF00069	0.777
MOD_ProDKin_1	376	382	PF00069	0.702
MOD_ProDKin_1	589	595	PF00069	0.659
MOD_ProDKin_1	59	65	PF00069	0.728
MOD_ProDKin_1	66	72	PF00069	0.653
MOD_ProDKin_1	801	807	PF00069	0.684
MOD_ProDKin_1	814	820	PF00069	0.606
MOD_ProDKin_1	923	929	PF00069	0.590
MOD_ProDKin_1	99	105	PF00069	0.680
TRG_DiLeu_BaEn_1	207	212	PF01217	0.678
TRG_DiLeu_BaLyEn_6	1	6	PF01217	0.668
TRG_DiLeu_BaLyEn_6	920	925	PF01217	0.657
TRG_ENDOCYTIC_2	153	156	PF00928	0.670
TRG_ENDOCYTIC_2	167	170	PF00928	0.551
TRG_ENDOCYTIC_2	513	516	PF00928	0.798
TRG_ENDOCYTIC_2	558	561	PF00928	0.715
TRG_ENDOCYTIC_2	607	610	PF00928	0.664
TRG_ENDOCYTIC_2	921	924	PF00928	0.667
TRG_ER_diArg_1	189	191	PF00400	0.758
TRG_ER_diArg_1	261	264	PF00400	0.810
TRG_ER_diArg_1	274	277	PF00400	0.613
TRG_ER_diArg_1	414	417	PF00400	0.762
TRG_ER_diArg_1	546	549	PF00400	0.750
TRG_ER_diArg_1	55	57	PF00400	0.680
TRG_ER_diArg_1	648	650	PF00400	0.724
TRG_ER_diArg_1	676	678	PF00400	0.722
TRG_ER_diArg_1	75	77	PF00400	0.496
TRG_ER_diArg_1	782	785	PF00400	0.746
TRG_ER_diArg_1	810	812	PF00400	0.672
TRG_ER_diArg_1	864	867	PF00400	0.797
TRG_ER_diArg_1	899	901	PF00400	0.725
TRG_ER_diArg_1	99	101	PF00400	0.687
TRG_NLS_MonoExtC_3	784	790	PF00514	0.685
TRG_NLS_MonoExtN_4	782	789	PF00514	0.679
TRG_Pf-PMV_PEXEL_1	4	8	PF00026	0.748

Homologs


Protein	Taxonomy	Sequence identity	Coverage
E9AWA0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	57%	100%