Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HCT4_LEIBR

TriTrypDb:

LbrM.23.0730 , LBRM2903_230015100

Length:

462

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HCT4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HCT4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	367	371	PF00656	0.597
CLV_NRD_NRD_1	261	263	PF00675	0.832
CLV_NRD_NRD_1	341	343	PF00675	0.778
CLV_NRD_NRD_1	383	385	PF00675	0.651
CLV_NRD_NRD_1	396	398	PF00675	0.433
CLV_NRD_NRD_1	423	425	PF00675	0.640
CLV_NRD_NRD_1	48	50	PF00675	0.847
CLV_PCSK_KEX2_1	260	262	PF00082	0.837
CLV_PCSK_KEX2_1	340	342	PF00082	0.778
CLV_PCSK_KEX2_1	383	385	PF00082	0.651
CLV_PCSK_KEX2_1	395	397	PF00082	0.458
CLV_PCSK_KEX2_1	423	425	PF00082	0.640
CLV_PCSK_KEX2_1	47	49	PF00082	0.855
CLV_PCSK_PC1ET2_1	260	262	PF00082	0.837
CLV_PCSK_PC1ET2_1	340	342	PF00082	0.778
CLV_PCSK_PC7_1	256	262	PF00082	0.837
CLV_PCSK_PC7_1	392	398	PF00082	0.697
CLV_PCSK_SKI1_1	114	118	PF00082	0.852
CLV_PCSK_SKI1_1	141	145	PF00082	0.824
CLV_PCSK_SKI1_1	193	197	PF00082	0.854
CLV_PCSK_SKI1_1	228	232	PF00082	0.675
CLV_PCSK_SKI1_1	256	260	PF00082	0.837
CLV_PCSK_SKI1_1	426	430	PF00082	0.647
DEG_APCC_DBOX_1	396	404	PF00400	0.636
DEG_APCC_DBOX_1	425	433	PF00400	0.636
DEG_Nend_UBRbox_2	1	3	PF02207	0.813
DEG_SPOP_SBC_1	240	244	PF00917	0.816
DEG_SPOP_SBC_1	296	300	PF00917	0.820
DOC_CYCLIN_RxL_1	378	391	PF00134	0.650
DOC_CYCLIN_RxL_1	63	72	PF00134	0.753
DOC_MAPK_DCC_7	282	292	PF00069	0.839
DOC_MAPK_gen_1	320	328	PF00069	0.793
DOC_MAPK_gen_1	423	431	PF00069	0.643
DOC_MAPK_gen_1	47	59	PF00069	0.794
DOC_MAPK_HePTP_8	45	59	PF00069	0.804
DOC_MAPK_MEF2A_6	282	290	PF00069	0.837
DOC_MAPK_MEF2A_6	320	328	PF00069	0.793
DOC_MAPK_MEF2A_6	351	358	PF00069	0.611
DOC_MAPK_MEF2A_6	52	59	PF00069	0.763
DOC_PP2B_LxvP_1	123	126	PF13499	0.839
DOC_SPAK_OSR1_1	208	212	PF12202	0.660
DOC_USP7_MATH_1	118	122	PF00917	0.868
DOC_USP7_MATH_1	241	245	PF00917	0.824
DOC_USP7_MATH_1	40	44	PF00917	0.870
DOC_USP7_MATH_1	422	426	PF00917	0.636
DOC_USP7_MATH_1	83	87	PF00917	0.808
DOC_USP7_MATH_1	96	100	PF00917	0.613
DOC_WW_Pin1_4	135	140	PF00397	0.826
DOC_WW_Pin1_4	185	190	PF00397	0.840
DOC_WW_Pin1_4	282	287	PF00397	0.841
DOC_WW_Pin1_4	297	302	PF00397	0.554
LIG_14-3-3_CanoR_1	102	107	PF00244	0.859
LIG_14-3-3_CanoR_1	128	135	PF00244	0.850
LIG_14-3-3_CanoR_1	141	150	PF00244	0.594
LIG_14-3-3_CanoR_1	201	207	PF00244	0.768
LIG_14-3-3_CanoR_1	280	286	PF00244	0.852
LIG_14-3-3_CanoR_1	423	429	PF00244	0.640
LIG_Actin_WH2_2	400	418	PF00022	0.610
LIG_BIR_III_4	450	454	PF00653	0.616
LIG_BRCT_BRCA1_1	301	305	PF00533	0.817
LIG_EH_1	322	326	PF12763	0.784
LIG_eIF4E_1	408	414	PF01652	0.599
LIG_FHA_1	135	141	PF00498	0.827
LIG_FHA_1	153	159	PF00498	0.497
LIG_FHA_1	389	395	PF00498	0.716
LIG_FHA_1	408	414	PF00498	0.267
LIG_FHA_2	189	195	PF00498	0.849
LIG_HCF-1_HBM_1	377	380	PF13415	0.621
LIG_LIR_Gen_1	402	411	PF02991	0.611
LIG_LIR_Nem_3	402	407	PF02991	0.624
LIG_LIR_Nem_3	447	452	PF02991	0.615
LIG_LRP6_Inhibitor_1	250	256	PF00058	0.849
LIG_LYPXL_S_1	407	411	PF13949	0.589
LIG_LYPXL_yS_3	408	411	PF13949	0.591
LIG_PCNA_yPIPBox_3	66	74	PF02747	0.762
LIG_SH2_CRK	404	408	PF00017	0.616
LIG_SH2_CRK	449	453	PF00017	0.609
LIG_SH2_GRB2like	404	407	PF00017	0.627
LIG_SH2_NCK_1	449	453	PF00017	0.609
LIG_SH2_STAP1	361	365	PF00017	0.624
LIG_SH2_STAT3	417	420	PF00017	0.601
LIG_SH2_STAT5	237	240	PF00017	0.765
LIG_SH2_STAT5	381	384	PF00017	0.629
LIG_SH2_STAT5	417	420	PF00017	0.601
LIG_SH3_3	283	289	PF00018	0.828
LIG_SH3_3	321	327	PF00018	0.790
LIG_SH3_3	87	93	PF00018	0.833
LIG_SUMO_SIM_anti_2	2	7	PF11976	0.799
LIG_SUMO_SIM_par_1	444	450	PF11976	0.619
LIG_TYR_ITIM	359	364	PF00017	0.614
LIG_WW_2	286	289	PF00397	0.810
MOD_CDC14_SPxK_1	138	141	PF00782	0.817
MOD_CDK_SPK_2	185	190	PF00069	0.840
MOD_CDK_SPxK_1	135	141	PF00069	0.827
MOD_CK1_1	145	151	PF00069	0.819
MOD_CK1_1	243	249	PF00069	0.839
MOD_CK1_1	281	287	PF00069	0.844
MOD_CK1_1	295	301	PF00069	0.574
MOD_CK1_1	38	44	PF00069	0.870
MOD_CK2_1	188	194	PF00069	0.849
MOD_CK2_1	456	462	PF00069	0.743
MOD_CK2_1	69	75	PF00069	0.764
MOD_DYRK1A_RPxSP_1	282	286	PF00069	0.846
MOD_GlcNHglycan	120	123	PF01048	0.873
MOD_GlcNHglycan	129	132	PF01048	0.697
MOD_GlcNHglycan	144	147	PF01048	0.560
MOD_GlcNHglycan	170	173	PF01048	0.825
MOD_GlcNHglycan	179	182	PF01048	0.691
MOD_GlcNHglycan	292	295	PF01048	0.839
MOD_GlcNHglycan	301	304	PF01048	0.657
MOD_GlcNHglycan	37	40	PF01048	0.861
MOD_GlcNHglycan	441	444	PF01048	0.608
MOD_GlcNHglycan	458	461	PF01048	0.463
MOD_GlcNHglycan	84	89	PF01048	0.822
MOD_GlcNHglycan	94	97	PF01048	0.665
MOD_GSK3_1	127	134	PF00069	0.850
MOD_GSK3_1	141	148	PF00069	0.578
MOD_GSK3_1	152	159	PF00069	0.619
MOD_GSK3_1	164	171	PF00069	0.607
MOD_GSK3_1	177	184	PF00069	0.614
MOD_GSK3_1	193	200	PF00069	0.565
MOD_GSK3_1	239	246	PF00069	0.817
MOD_GSK3_1	276	283	PF00069	0.863
MOD_GSK3_1	28	35	PF00069	0.849
MOD_GSK3_1	292	299	PF00069	0.549
MOD_GSK3_1	359	366	PF00069	0.621
MOD_GSK3_1	92	99	PF00069	0.837
MOD_N-GLC_1	177	182	PF02516	0.847
MOD_N-GLC_1	185	190	PF02516	0.700
MOD_NEK2_1	149	154	PF00069	0.812
MOD_NEK2_1	177	182	PF00069	0.847
MOD_NEK2_1	268	273	PF00069	0.841
MOD_NEK2_1	290	295	PF00069	0.842
MOD_NEK2_1	311	316	PF00069	0.791
MOD_NEK2_1	431	436	PF00069	0.644
MOD_PIKK_1	245	251	PF00454	0.846
MOD_PK_1	424	430	PF00069	0.645
MOD_PKA_1	48	54	PF00069	0.821
MOD_PKA_2	127	133	PF00069	0.853
MOD_PKA_2	200	206	PF00069	0.787
MOD_PKA_2	281	287	PF00069	0.844
MOD_PKA_2	32	38	PF00069	0.864
MOD_PKA_2	422	428	PF00069	0.632
MOD_PKA_2	453	459	PF00069	0.670
MOD_PKA_2	48	54	PF00069	0.540
MOD_Plk_1	193	199	PF00069	0.849
MOD_Plk_1	74	80	PF00069	0.776
MOD_Plk_4	145	151	PF00069	0.819
MOD_Plk_4	172	178	PF00069	0.837
MOD_Plk_4	193	199	PF00069	0.849
MOD_Plk_4	202	208	PF00069	0.597
MOD_Plk_4	41	47	PF00069	0.872
MOD_Plk_4	69	75	PF00069	0.764
MOD_ProDKin_1	135	141	PF00069	0.827
MOD_ProDKin_1	185	191	PF00069	0.843
MOD_ProDKin_1	282	288	PF00069	0.841
MOD_ProDKin_1	297	303	PF00069	0.554
TRG_DiLeu_BaEn_2	320	326	PF01217	0.791
TRG_ENDOCYTIC_2	361	364	PF00928	0.622
TRG_ENDOCYTIC_2	404	407	PF00928	0.627
TRG_ENDOCYTIC_2	408	411	PF00928	0.521
TRG_ENDOCYTIC_2	449	452	PF00928	0.612
TRG_ER_diArg_1	382	384	PF00400	0.638
TRG_ER_diArg_1	394	397	PF00400	0.469
TRG_ER_diArg_1	423	426	PF00400	0.651
TRG_ER_diArg_1	46	49	PF00400	0.860
TRG_NLS_MonoCore_2	258	263	PF00514	0.833
TRG_NLS_MonoExtC_3	259	265	PF00514	0.833
TRG_NLS_MonoExtN_4	256	263	PF00514	0.835
TRG_Pf-PMV_PEXEL_1	190	194	PF00026	0.854
TRG_Pf-PMV_PEXEL_1	416	420	PF00026	0.608
TRG_Pf-PMV_PEXEL_1	66	71	PF00026	0.760