Putative ubiquitin-activating enzyme e1

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ubiquitin-activating enzyme E1, putative

Species:

Leishmania braziliensis

UniProt:

A4HCT1_LEIBR

TriTrypDb:

LbrM.23.0700 , LBRM2903_230014700

Length:

1045

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 3
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 16

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 6

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 6

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	1
GO:0005654	nucleoplasm	2	1
GO:0005737	cytoplasm	2	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4HCT1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HCT1

Function

Biological processes
Term	Name	Level	Count
GO:0006807	nitrogen compound metabolic process	2	11
GO:0008152	metabolic process	1	11
GO:0016567	protein ubiquitination	7	11
GO:0019538	protein metabolic process	3	11
GO:0032446	protein modification by small protein conjugation	6	11
GO:0036211	protein modification process	4	11
GO:0043170	macromolecule metabolic process	3	11
GO:0043412	macromolecule modification	4	11
GO:0044238	primary metabolic process	2	11
GO:0070647	protein modification by small protein conjugation or removal	5	11
GO:0071704	organic substance metabolic process	2	11
GO:1901564	organonitrogen compound metabolic process	3	11
GO:0006508	proteolysis	4	1
GO:0006511	ubiquitin-dependent protein catabolic process	7	1
GO:0006950	response to stress	2	1
GO:0006974	DNA damage response	4	1
GO:0009056	catabolic process	2	1
GO:0009057	macromolecule catabolic process	4	1
GO:0009987	cellular process	1	1
GO:0019941	modification-dependent protein catabolic process	6	1
GO:0033554	cellular response to stress	3	1
GO:0043632	modification-dependent macromolecule catabolic process	5	1
GO:0044237	cellular metabolic process	2	1
GO:0044248	cellular catabolic process	3	1
GO:0044260	obsolete cellular macromolecule metabolic process	3	1
GO:0044265	obsolete cellular macromolecule catabolic process	4	1
GO:0050896	response to stimulus	1	1
GO:0051603	proteolysis involved in protein catabolic process	5	1
GO:0051716	cellular response to stimulus	2	1
GO:1901575	organic substance catabolic process	3	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	8
GO:0003824	catalytic activity	1	12
GO:0005488	binding	1	8
GO:0005524	ATP binding	5	8
GO:0008641	ubiquitin-like modifier activating enzyme activity	2	12
GO:0016874	ligase activity	2	12
GO:0016877	ligase activity, forming carbon-sulfur bonds	3	12
GO:0017076	purine nucleotide binding	4	8
GO:0030554	adenyl nucleotide binding	5	8
GO:0032553	ribonucleotide binding	3	8
GO:0032555	purine ribonucleotide binding	4	8
GO:0032559	adenyl ribonucleotide binding	5	8
GO:0035639	purine ribonucleoside triphosphate binding	4	8
GO:0036094	small molecule binding	2	8
GO:0043167	ion binding	2	8
GO:0043168	anion binding	3	8
GO:0097159	organic cyclic compound binding	2	8
GO:0097367	carbohydrate derivative binding	2	8
GO:0140096	catalytic activity, acting on a protein	2	12
GO:0140657	ATP-dependent activity	1	12
GO:1901265	nucleoside phosphate binding	3	8
GO:1901363	heterocyclic compound binding	2	8
GO:0004839	ubiquitin activating enzyme activity	3	1
GO:0004842	ubiquitin-protein transferase activity	4	1
GO:0016740	transferase activity	2	1
GO:0016746	acyltransferase activity	3	1
GO:0019787	ubiquitin-like protein transferase activity	3	1
GO:0061631	ubiquitin conjugating enzyme activity	5	1
GO:0061650	ubiquitin-like protein conjugating enzyme activity	4	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1012	1016	PF00656	0.467
CLV_C14_Caspase3-7	163	167	PF00656	0.354
CLV_NRD_NRD_1	268	270	PF00675	0.393
CLV_NRD_NRD_1	544	546	PF00675	0.295
CLV_NRD_NRD_1	660	662	PF00675	0.310
CLV_NRD_NRD_1	801	803	PF00675	0.282
CLV_NRD_NRD_1	879	881	PF00675	0.579
CLV_PCSK_KEX2_1	1000	1002	PF00082	0.311
CLV_PCSK_KEX2_1	268	270	PF00082	0.332
CLV_PCSK_KEX2_1	660	662	PF00082	0.310
CLV_PCSK_KEX2_1	696	698	PF00082	0.268
CLV_PCSK_KEX2_1	8	10	PF00082	0.435
CLV_PCSK_KEX2_1	801	803	PF00082	0.282
CLV_PCSK_KEX2_1	843	845	PF00082	0.309
CLV_PCSK_PC1ET2_1	1000	1002	PF00082	0.311
CLV_PCSK_PC1ET2_1	696	698	PF00082	0.268
CLV_PCSK_PC1ET2_1	8	10	PF00082	0.480
CLV_PCSK_PC1ET2_1	843	845	PF00082	0.328
CLV_PCSK_SKI1_1	340	344	PF00082	0.328
CLV_PCSK_SKI1_1	385	389	PF00082	0.309
CLV_PCSK_SKI1_1	479	483	PF00082	0.294
CLV_PCSK_SKI1_1	54	58	PF00082	0.366
CLV_PCSK_SKI1_1	551	555	PF00082	0.298
CLV_PCSK_SKI1_1	557	561	PF00082	0.288
CLV_PCSK_SKI1_1	613	617	PF00082	0.359
CLV_PCSK_SKI1_1	686	690	PF00082	0.263
CLV_PCSK_SKI1_1	870	874	PF00082	0.309
CLV_PCSK_SKI1_1	905	909	PF00082	0.447
CLV_PCSK_SKI1_1	911	915	PF00082	0.345
CLV_PCSK_SKI1_1	957	961	PF00082	0.300
DEG_APCC_DBOX_1	685	693	PF00400	0.468
DEG_COP1_1	215	223	PF00400	0.213
DEG_Nend_Nbox_1	1	3	PF02207	0.628
DEG_SPOP_SBC_1	123	127	PF00917	0.370
DEG_SPOP_SBC_1	854	858	PF00917	0.353
DOC_CYCLIN_RxL_1	551	564	PF00134	0.296
DOC_CYCLIN_yCln2_LP_2	110	116	PF00134	0.346
DOC_CYCLIN_yCln2_LP_2	631	637	PF00134	0.500
DOC_MAPK_gen_1	969	976	PF00069	0.481
DOC_MAPK_HePTP_8	565	577	PF00069	0.437
DOC_MAPK_MEF2A_6	568	577	PF00069	0.437
DOC_MAPK_MEF2A_6	911	919	PF00069	0.320
DOC_MAPK_MEF2A_6	969	978	PF00069	0.469
DOC_PP1_RVXF_1	137	143	PF00149	0.370
DOC_PP1_RVXF_1	199	205	PF00149	0.437
DOC_PP1_RVXF_1	939	946	PF00149	0.536
DOC_PP2B_LxvP_1	110	113	PF13499	0.346
DOC_PP4_FxxP_1	74	77	PF00568	0.328
DOC_PP4_FxxP_1	924	927	PF00568	0.337
DOC_USP7_MATH_1	123	127	PF00917	0.370
DOC_USP7_MATH_1	219	223	PF00917	0.358
DOC_USP7_MATH_1	402	406	PF00917	0.595
DOC_USP7_MATH_1	415	419	PF00917	0.409
DOC_USP7_MATH_1	879	883	PF00917	0.607
DOC_USP7_MATH_1	936	940	PF00917	0.466
DOC_USP7_UBL2_3	709	713	PF12436	0.478
DOC_USP7_UBL2_3	994	998	PF12436	0.487
DOC_WW_Pin1_4	178	183	PF00397	0.358
DOC_WW_Pin1_4	231	236	PF00397	0.265
DOC_WW_Pin1_4	313	318	PF00397	0.353
DOC_WW_Pin1_4	371	376	PF00397	0.294
DOC_WW_Pin1_4	507	512	PF00397	0.361
LIG_14-3-3_CanoR_1	141	150	PF00244	0.461
LIG_14-3-3_CanoR_1	490	495	PF00244	0.437
LIG_14-3-3_CanoR_1	775	783	PF00244	0.488
LIG_Actin_WH2_2	225	243	PF00022	0.370
LIG_AP2alpha_1	681	685	PF02296	0.482
LIG_APCC_ABBA_1	186	191	PF00400	0.309
LIG_BRCT_BRCA1_1	369	373	PF00533	0.294
LIG_BRCT_BRCA1_1	477	481	PF00533	0.294
LIG_Clathr_ClatBox_1	285	289	PF01394	0.467
LIG_Clathr_ClatBox_1	863	867	PF01394	0.309
LIG_eIF4E_1	729	735	PF01652	0.468
LIG_FHA_1	1023	1029	PF00498	0.482
LIG_FHA_1	123	129	PF00498	0.302
LIG_FHA_1	172	178	PF00498	0.483
LIG_FHA_1	235	241	PF00498	0.457
LIG_FHA_1	28	34	PF00498	0.309
LIG_FHA_1	352	358	PF00498	0.323
LIG_FHA_1	518	524	PF00498	0.318
LIG_FHA_1	840	846	PF00498	0.471
LIG_FHA_1	854	860	PF00498	0.378
LIG_FHA_2	1010	1016	PF00498	0.431
LIG_FHA_2	185	191	PF00498	0.213
LIG_FHA_2	272	278	PF00498	0.396
LIG_FHA_2	465	471	PF00498	0.295
LIG_FHA_2	508	514	PF00498	0.370
LIG_FHA_2	63	69	PF00498	0.360
LIG_IRF3_LxIS_1	947	954	PF10401	0.213
LIG_KLC1_Yacidic_2	893	898	PF13176	0.423
LIG_LIR_Apic_2	583	589	PF02991	0.353
LIG_LIR_Apic_2	71	77	PF02991	0.328
LIG_LIR_Apic_2	932	938	PF02991	0.430
LIG_LIR_Gen_1	1018	1028	PF02991	0.559
LIG_LIR_Gen_1	614	624	PF02991	0.457
LIG_LIR_Gen_1	912	922	PF02991	0.365
LIG_LIR_LC3C_4	1021	1024	PF02991	0.559
LIG_LIR_LC3C_4	30	35	PF02991	0.309
LIG_LIR_Nem_3	1018	1023	PF02991	0.559
LIG_LIR_Nem_3	222	227	PF02991	0.437
LIG_LIR_Nem_3	270	275	PF02991	0.378
LIG_LIR_Nem_3	370	376	PF02991	0.294
LIG_LIR_Nem_3	614	619	PF02991	0.457
LIG_LIR_Nem_3	683	688	PF02991	0.474
LIG_LIR_Nem_3	912	917	PF02991	0.364
LIG_NRBOX	614	620	PF00104	0.559
LIG_NRBOX	671	677	PF00104	0.554
LIG_NRBOX	868	874	PF00104	0.309
LIG_NRBOX	963	969	PF00104	0.524
LIG_PDZ_Class_2	1040	1045	PF00595	0.460
LIG_Pex14_2	524	528	PF04695	0.294
LIG_Pex14_2	616	620	PF04695	0.457
LIG_Pex14_2	681	685	PF04695	0.461
LIG_Pex14_2	910	914	PF04695	0.464
LIG_PTB_Apo_2	522	529	PF02174	0.328
LIG_REV1ctd_RIR_1	71	76	PF16727	0.346
LIG_SH2_CRK	272	276	PF00017	0.346
LIG_SH2_CRK	555	559	PF00017	0.328
LIG_SH2_CRK	739	743	PF00017	0.500
LIG_SH2_CRK	832	836	PF00017	0.464
LIG_SH2_CRK	935	939	PF00017	0.461
LIG_SH2_GRB2like	120	123	PF00017	0.437
LIG_SH2_NCK_1	120	124	PF00017	0.370
LIG_SH2_NCK_1	586	590	PF00017	0.353
LIG_SH2_NCK_1	832	836	PF00017	0.438
LIG_SH2_NCK_1	935	939	PF00017	0.528
LIG_SH2_SRC	547	550	PF00017	0.309
LIG_SH2_SRC	586	589	PF00017	0.389
LIG_SH2_SRC	677	680	PF00017	0.559
LIG_SH2_SRC	896	899	PF00017	0.646
LIG_SH2_STAP1	120	124	PF00017	0.437
LIG_SH2_STAP1	582	586	PF00017	0.328
LIG_SH2_STAP1	972	976	PF00017	0.559
LIG_SH2_STAT3	12	15	PF00017	0.309
LIG_SH2_STAT3	420	423	PF00017	0.309
LIG_SH2_STAT3	434	437	PF00017	0.309
LIG_SH2_STAT5	1019	1022	PF00017	0.559
LIG_SH2_STAT5	120	123	PF00017	0.437
LIG_SH2_STAT5	124	127	PF00017	0.437
LIG_SH2_STAT5	17	20	PF00017	0.309
LIG_SH2_STAT5	203	206	PF00017	0.388
LIG_SH2_STAT5	260	263	PF00017	0.294
LIG_SH2_STAT5	434	437	PF00017	0.328
LIG_SH2_STAT5	547	550	PF00017	0.334
LIG_SH2_STAT5	630	633	PF00017	0.457
LIG_SH2_STAT5	871	874	PF00017	0.341
LIG_SH2_STAT5	896	899	PF00017	0.637
LIG_SH2_STAT5	988	991	PF00017	0.559
LIG_SH3_2	414	419	PF14604	0.336
LIG_SH3_3	1031	1037	PF00018	0.470
LIG_SH3_3	215	221	PF00018	0.374
LIG_SH3_3	229	235	PF00018	0.294
LIG_SH3_3	311	317	PF00018	0.437
LIG_SH3_3	408	414	PF00018	0.502
LIG_SH3_3	570	576	PF00018	0.392
LIG_SH3_3	618	624	PF00018	0.559
LIG_SH3_3	708	714	PF00018	0.457
LIG_SH3_3	755	761	PF00018	0.518
LIG_SH3_3	77	83	PF00018	0.262
LIG_Sin3_3	1020	1027	PF02671	0.559
LIG_SUMO_SIM_anti_2	160	168	PF11976	0.437
LIG_SUMO_SIM_anti_2	29	36	PF11976	0.311
LIG_SUMO_SIM_par_1	183	191	PF11976	0.303
LIG_SUMO_SIM_par_1	251	258	PF11976	0.323
LIG_SUMO_SIM_par_1	62	68	PF11976	0.439
LIG_TRAF2_1	361	364	PF00917	0.294
LIG_TRAF2_1	421	424	PF00917	0.437
LIG_TRAF2_1	747	750	PF00917	0.524
LIG_TRAF2_1	899	902	PF00917	0.579
LIG_TRFH_1	73	77	PF08558	0.328
LIG_TRFH_1	739	743	PF08558	0.478
LIG_TYR_ITIM	1017	1022	PF00017	0.559
LIG_TYR_ITIM	869	874	PF00017	0.353
LIG_UBA3_1	688	696	PF00899	0.468
LIG_UBA3_1	978	985	PF00899	0.457
LIG_ULM_U2AF65_1	941	946	PF00076	0.461
MOD_CK1_1	102	108	PF00069	0.437
MOD_CK1_1	126	132	PF00069	0.485
MOD_CK1_1	144	150	PF00069	0.422
MOD_CK1_1	234	240	PF00069	0.491
MOD_CK1_1	475	481	PF00069	0.294
MOD_CK1_1	581	587	PF00069	0.328
MOD_CK1_1	778	784	PF00069	0.555
MOD_CK1_1	785	791	PF00069	0.440
MOD_CK1_1	858	864	PF00069	0.353
MOD_CK2_1	1005	1011	PF00069	0.485
MOD_CK2_1	164	170	PF00069	0.353
MOD_CK2_1	184	190	PF00069	0.165
MOD_CK2_1	271	277	PF00069	0.437
MOD_CK2_1	313	319	PF00069	0.309
MOD_CK2_1	507	513	PF00069	0.369
MOD_CK2_1	744	750	PF00069	0.485
MOD_CK2_1	887	893	PF00069	0.538
MOD_CMANNOS	945	948	PF00535	0.355
MOD_Cter_Amidation	266	269	PF01082	0.370
MOD_Cter_Amidation	939	942	PF01082	0.495
MOD_GlcNHglycan	104	107	PF01048	0.370
MOD_GlcNHglycan	207	210	PF01048	0.213
MOD_GlcNHglycan	221	224	PF01048	0.437
MOD_GlcNHglycan	247	250	PF01048	0.423
MOD_GlcNHglycan	257	260	PF01048	0.216
MOD_GlcNHglycan	369	372	PF01048	0.294
MOD_GlcNHglycan	398	401	PF01048	0.673
MOD_GlcNHglycan	405	408	PF01048	0.580
MOD_GlcNHglycan	561	564	PF01048	0.327
MOD_GlcNHglycan	705	708	PF01048	0.238
MOD_GlcNHglycan	784	787	PF01048	0.343
MOD_GlcNHglycan	881	884	PF01048	0.511
MOD_GlcNHglycan	911	914	PF01048	0.481
MOD_GlcNHglycan	938	941	PF01048	0.586
MOD_GSK3_1	1005	1012	PF00069	0.505
MOD_GSK3_1	118	125	PF00069	0.483
MOD_GSK3_1	171	178	PF00069	0.315
MOD_GSK3_1	271	278	PF00069	0.248
MOD_GSK3_1	367	374	PF00069	0.294
MOD_GSK3_1	394	401	PF00069	0.603
MOD_GSK3_1	464	471	PF00069	0.309
MOD_GSK3_1	48	55	PF00069	0.328
MOD_GSK3_1	576	583	PF00069	0.294
MOD_GSK3_1	744	751	PF00069	0.561
MOD_GSK3_1	770	777	PF00069	0.540
MOD_GSK3_1	778	785	PF00069	0.522
MOD_GSK3_1	793	800	PF00069	0.563
MOD_GSK3_1	854	861	PF00069	0.308
MOD_GSK3_1	905	912	PF00069	0.515
MOD_N-GLC_1	213	218	PF02516	0.437
MOD_N-GLC_1	475	480	PF02516	0.294
MOD_N-GLC_1	839	844	PF02516	0.359
MOD_NEK2_1	1022	1027	PF00069	0.468
MOD_NEK2_1	261	266	PF00069	0.294
MOD_NEK2_1	275	280	PF00069	0.294
MOD_NEK2_1	398	403	PF00069	0.640
MOD_NEK2_1	559	564	PF00069	0.294
MOD_NEK2_1	619	624	PF00069	0.482
MOD_NEK2_1	703	708	PF00069	0.451
MOD_NEK2_1	839	844	PF00069	0.529
MOD_NEK2_1	853	858	PF00069	0.285
MOD_NEK2_1	909	914	PF00069	0.491
MOD_NEK2_2	184	189	PF00069	0.309
MOD_NEK2_2	296	301	PF00069	0.437
MOD_NEK2_2	52	57	PF00069	0.353
MOD_NEK2_2	594	599	PF00069	0.294
MOD_PIKK_1	20	26	PF00454	0.328
MOD_PIKK_1	775	781	PF00454	0.518
MOD_PIKK_1	793	799	PF00454	0.438
MOD_PK_1	490	496	PF00069	0.437
MOD_PKA_1	1000	1006	PF00069	0.511
MOD_PKA_2	1000	1006	PF00069	0.511
MOD_PKA_2	774	780	PF00069	0.399
MOD_PKA_2	879	885	PF00069	0.504
MOD_Plk_1	169	175	PF00069	0.294
MOD_Plk_1	462	468	PF00069	0.370
MOD_Plk_1	605	611	PF00069	0.488
MOD_Plk_1	748	754	PF00069	0.445
MOD_Plk_1	99	105	PF00069	0.429
MOD_Plk_2-3	468	474	PF00069	0.309
MOD_Plk_2-3	695	701	PF00069	0.399
MOD_Plk_4	1009	1015	PF00069	0.422
MOD_Plk_4	319	325	PF00069	0.323
MOD_Plk_4	490	496	PF00069	0.426
MOD_Plk_4	647	653	PF00069	0.420
MOD_Plk_4	855	861	PF00069	0.363
MOD_Plk_4	905	911	PF00069	0.366
MOD_ProDKin_1	178	184	PF00069	0.358
MOD_ProDKin_1	231	237	PF00069	0.265
MOD_ProDKin_1	313	319	PF00069	0.353
MOD_ProDKin_1	371	377	PF00069	0.294
MOD_ProDKin_1	507	513	PF00069	0.361
MOD_SUMO_for_1	663	666	PF00179	0.399
MOD_SUMO_rev_2	133	140	PF00179	0.213
MOD_SUMO_rev_2	289	295	PF00179	0.298
TRG_DiLeu_BaEn_1	902	907	PF01217	0.510
TRG_DiLeu_BaEn_1	963	968	PF01217	0.511
TRG_DiLeu_BaEn_2	93	99	PF01217	0.309
TRG_DiLeu_BaEn_2	972	978	PF01217	0.559
TRG_DiLeu_BaEn_4	667	673	PF01217	0.399
TRG_DiLeu_BaLyEn_6	105	110	PF01217	0.346
TRG_DiLeu_BaLyEn_6	555	560	PF01217	0.370
TRG_DiLeu_BaLyEn_6	671	676	PF01217	0.554
TRG_ENDOCYTIC_2	1019	1022	PF00928	0.559
TRG_ENDOCYTIC_2	272	275	PF00928	0.437
TRG_ENDOCYTIC_2	871	874	PF00928	0.353
TRG_ENDOCYTIC_2	988	991	PF00928	0.457
TRG_ER_diArg_1	659	661	PF00400	0.557
TRG_ER_diArg_1	801	804	PF00400	0.482
TRG_ER_diArg_1	827	830	PF00400	0.551
TRG_NES_CRM1_1	614	626	PF08389	0.511
TRG_NLS_MonoExtC_3	264	269	PF00514	0.370
TRG_NLS_MonoExtN_4	938	945	PF00514	0.475
TRG_Pf-PMV_PEXEL_1	273	277	PF00026	0.370
TRG_Pf-PMV_PEXEL_1	551	556	PF00026	0.333
TRG_Pf-PMV_PEXEL_1	557	561	PF00026	0.285
TRG_Pf-PMV_PEXEL_1	674	678	PF00026	0.268

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I0Q7	Leptomonas seymouri	78%	100%
A0A0N1IJ85	Leptomonas seymouri	30%	90%
A0A0S4IRG8	Bodo saltans	44%	100%
A0A0S4JDE8	Bodo saltans	30%	85%
A0A1X0NX04	Trypanosomatidae	55%	97%
A0A1X0P5N5	Trypanosomatidae	29%	86%
A0A3Q8IIG4	Leishmania donovani	29%	91%
A0A3R7MAM2	Trypanosoma rangeli	30%	86%
A0A3R7MK28	Trypanosoma rangeli	56%	100%
A0A3S7WXL3	Leishmania donovani	89%	100%
A0AVT1	Homo sapiens	33%	99%
A3KMV5	Bos taurus	36%	99%
A4HMX3	Leishmania braziliensis	29%	91%
A4I0A5	Leishmania infantum	89%	100%
A4IBJ4	Leishmania infantum	29%	91%
C9ZV28	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	55%	99%
C9ZZ47	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	86%
E9AFD0	Leishmania major	28%	100%
E9AW70	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
E9B6I5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	91%
O94609	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	35%	100%
P20973	Triticum aestivum	34%	99%
P22314	Homo sapiens	36%	99%
P22515	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	37%	100%
P31251	Triticum aestivum	34%	99%
P31252	Triticum aestivum	32%	99%
P31254	Mus musculus	36%	99%
P41226	Homo sapiens	30%	100%
P52495	Candida albicans (strain WO-1)	36%	100%
P92974	Arabidopsis thaliana	33%	97%
P93028	Arabidopsis thaliana	33%	97%
Q02053	Mus musculus	36%	99%
Q29504	Oryctolagus cuniculus	36%	99%
Q55C16	Dictyostelium discoideum	35%	100%
Q5U300	Rattus norvegicus	36%	99%
Q8C7R4	Mus musculus	33%	99%
Q9NF77	Leishmania major	89%	100%
V5BB41	Trypanosoma cruzi	56%	100%