LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania braziliensis
UniProt:
A4HCQ6_LEIBR
TriTrypDb:
LbrM.23.0450 , LBRM2903_230010400
Length:
139

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HCQ6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HCQ6

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 45 47 PF00675 0.643
CLV_PCSK_KEX2_1 45 47 PF00082 0.643
DEG_Nend_UBRbox_3 1 3 PF02207 0.513
DEG_SPOP_SBC_1 68 72 PF00917 0.484
DOC_MAPK_gen_1 45 53 PF00069 0.464
DOC_MAPK_MEF2A_6 46 55 PF00069 0.511
DOC_PP2B_LxvP_1 51 54 PF13499 0.468
DOC_PP4_FxxP_1 58 61 PF00568 0.709
DOC_USP7_MATH_1 68 72 PF00917 0.502
DOC_WW_Pin1_4 56 61 PF00397 0.457
LIG_14-3-3_CanoR_1 91 98 PF00244 0.556
LIG_Actin_WH2_2 75 93 PF00022 0.571
LIG_BIR_III_2 49 53 PF00653 0.460
LIG_FHA_1 124 130 PF00498 0.436
LIG_FHA_1 71 77 PF00498 0.538
LIG_FHA_2 91 97 PF00498 0.556
LIG_GBD_Chelix_1 82 90 PF00786 0.552
LIG_LIR_Nem_3 92 98 PF02991 0.474
LIG_NRBOX 85 91 PF00104 0.555
LIG_SH2_CRK 48 52 PF00017 0.494
LIG_SH2_SRC 10 13 PF00017 0.497
LIG_SH2_STAT3 98 101 PF00017 0.545
LIG_SH3_3 20 26 PF00018 0.535
LIG_SH3_3 57 63 PF00018 0.565
LIG_SUMO_SIM_anti_2 85 94 PF11976 0.395
LIG_SUMO_SIM_par_1 69 78 PF11976 0.465
MOD_CDC14_SPxK_1 59 62 PF00782 0.465
MOD_CDK_SPxK_1 56 62 PF00069 0.460
MOD_CK1_1 18 24 PF00069 0.589
MOD_CK1_1 32 38 PF00069 0.539
MOD_CK1_1 70 76 PF00069 0.501
MOD_GlcNHglycan 20 23 PF01048 0.726
MOD_GlcNHglycan 36 39 PF01048 0.496
MOD_GlcNHglycan 41 44 PF01048 0.633
MOD_GSK3_1 1 8 PF00069 0.634
MOD_GSK3_1 119 126 PF00069 0.512
MOD_GSK3_1 21 28 PF00069 0.702
MOD_GSK3_1 29 36 PF00069 0.633
MOD_GSK3_1 68 75 PF00069 0.681
MOD_NEK2_1 1 6 PF00069 0.600
MOD_NEK2_1 123 128 PF00069 0.531
MOD_NEK2_1 34 39 PF00069 0.661
MOD_PKA_2 90 96 PF00069 0.557
MOD_Plk_1 119 125 PF00069 0.540
MOD_Plk_4 1 7 PF00069 0.753
MOD_ProDKin_1 56 62 PF00069 0.460
TRG_DiLeu_BaEn_1 12 17 PF01217 0.494
TRG_DiLeu_BaEn_1 85 90 PF01217 0.393
TRG_ENDOCYTIC_2 48 51 PF00928 0.465
TRG_NES_CRM1_1 106 120 PF08389 0.530

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8ILZ4 Leishmania donovani 61% 90%
A4I081 Leishmania infantum 60% 90%
E9AW45 Leishmania mexicana (strain MHOM/GT/2001/U1103) 65% 99%
Q4QBD2 Leishmania major 63% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS