Putative cytochrome c oxidase subunit 10

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

cytochrome c oxidase subunit 10, putative

Species:

Leishmania braziliensis

UniProt:

A4HCQ2_LEIBR

TriTrypDb:

LbrM.23.0410 , LBRM2903_230010000

Length:

119

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HCQ2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HCQ2

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	5
GO:0016491	oxidoreductase activity	2	5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	36	40	PF00656	0.494
CLV_NRD_NRD_1	3	5	PF00675	0.543
CLV_NRD_NRD_1	87	89	PF00675	0.437
CLV_PCSK_KEX2_1	3	5	PF00082	0.543
CLV_PCSK_KEX2_1	87	89	PF00082	0.434
CLV_PCSK_SKI1_1	101	105	PF00082	0.418
CLV_PCSK_SKI1_1	3	7	PF00082	0.625
CLV_PCSK_SKI1_1	80	84	PF00082	0.471
CLV_PCSK_SKI1_1	88	92	PF00082	0.437
DOC_MAPK_FxFP_2	24	27	PF00069	0.595
DOC_PP1_RVXF_1	61	68	PF00149	0.472
DOC_PP1_RVXF_1	86	93	PF00149	0.471
DOC_PP4_FxxP_1	24	27	PF00568	0.595
DOC_WW_Pin1_4	27	32	PF00397	0.562
DOC_WW_Pin1_4	80	85	PF00397	0.469
LIG_14-3-3_CanoR_1	101	106	PF00244	0.466
LIG_14-3-3_CanoR_1	3	12	PF00244	0.660
LIG_deltaCOP1_diTrp_1	89	99	PF00928	0.553
LIG_FHA_1	102	108	PF00498	0.395
LIG_FHA_1	4	10	PF00498	0.658
LIG_FHA_2	81	87	PF00498	0.457
LIG_HCF-1_HBM_1	112	115	PF13415	0.436
LIG_LIR_Gen_1	10	18	PF02991	0.446
LIG_LIR_Gen_1	64	74	PF02991	0.498
LIG_LIR_Nem_3	64	70	PF02991	0.506
LIG_LIR_Nem_3	98	103	PF02991	0.407
LIG_REV1ctd_RIR_1	97	105	PF16727	0.430
LIG_SH2_SRC	37	40	PF00017	0.588
LIG_SH2_STAT5	37	40	PF00017	0.443
LIG_SUMO_SIM_par_1	29	36	PF11976	0.514
LIG_TRAF2_1	83	86	PF00917	0.533
MOD_CDK_SPxxK_3	80	87	PF00069	0.463
MOD_CK1_1	7	13	PF00069	0.446
MOD_CK2_1	80	86	PF00069	0.450
MOD_GlcNHglycan	9	12	PF01048	0.707
MOD_GSK3_1	101	108	PF00069	0.418
MOD_GSK3_1	3	10	PF00069	0.438
MOD_PKA_1	3	9	PF00069	0.656
MOD_PKA_2	3	9	PF00069	0.656
MOD_ProDKin_1	27	33	PF00069	0.560
MOD_ProDKin_1	80	86	PF00069	0.469
TRG_ER_diArg_1	2	4	PF00400	0.551

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IKB5	Leptomonas seymouri	82%	100%
A0A0S4JCT0	Bodo saltans	73%	100%
A0A1X0NX91	Trypanosomatidae	74%	100%
A0A3S7WXI5	Leishmania donovani	86%	100%
A4I077	Leishmania infantum	86%	100%
D0A9J4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	71%	100%
D0A9J6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	71%	100%
E9AW41	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	100%
Q4QBD7	Leishmania major	86%	100%