LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HCN7_LEIBR
TriTrypDb:
LbrM.23.0250 , LBRM2903_230008200 *
Length:
160

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 7
NetGPI no yes: 0, no: 7
Cellular components
Term Name Level Count
GO:0016020 membrane 2 8
GO:0110165 cellular anatomical entity 1 8

Expansion

Sequence features

A4HCN7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HCN7

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 23 27 PF00656 0.701
CLV_NRD_NRD_1 47 49 PF00675 0.412
CLV_PCSK_KEX2_1 47 49 PF00082 0.412
CLV_PCSK_SKI1_1 11 15 PF00082 0.503
CLV_PCSK_SKI1_1 29 33 PF00082 0.452
CLV_PCSK_SKI1_1 99 103 PF00082 0.424
DEG_Nend_UBRbox_3 1 3 PF02207 0.611
DOC_CYCLIN_yClb3_PxF_3 52 58 PF00134 0.630
DOC_PP4_FxxP_1 58 61 PF00568 0.712
DOC_USP7_MATH_1 59 63 PF00917 0.610
DOC_WW_Pin1_4 48 53 PF00397 0.673
LIG_14-3-3_CanoR_1 99 108 PF00244 0.655
LIG_deltaCOP1_diTrp_1 138 148 PF00928 0.502
LIG_FHA_2 21 27 PF00498 0.702
LIG_FHA_2 62 68 PF00498 0.684
LIG_FHA_2 83 89 PF00498 0.569
LIG_GBD_Chelix_1 149 157 PF00786 0.207
LIG_LIR_Apic_2 14 20 PF02991 0.656
LIG_LIR_Gen_1 139 150 PF02991 0.502
LIG_LIR_Nem_3 138 144 PF02991 0.502
LIG_LIR_Nem_3 147 151 PF02991 0.354
LIG_MYND_1 120 124 PF01753 0.678
LIG_Pex14_2 148 152 PF04695 0.354
LIG_Rb_pABgroove_1 11 19 PF01858 0.587
LIG_SH2_CRK 130 134 PF00017 0.668
LIG_SH2_CRK 17 21 PF00017 0.597
LIG_SH2_STAP1 86 90 PF00017 0.573
LIG_SH3_1 47 53 PF00018 0.609
LIG_SH3_3 113 119 PF00018 0.655
LIG_SH3_3 121 127 PF00018 0.652
LIG_SH3_3 47 53 PF00018 0.676
LIG_UBA3_1 151 160 PF00899 0.354
LIG_WRC_WIRS_1 145 150 PF05994 0.354
LIG_WW_1 127 130 PF00397 0.582
MOD_CK1_1 82 88 PF00069 0.574
MOD_CK2_1 104 110 PF00069 0.648
MOD_DYRK1A_RPxSP_1 48 52 PF00069 0.608
MOD_GlcNHglycan 61 64 PF01048 0.568
MOD_NEK2_1 137 142 PF00069 0.595
MOD_NEK2_1 144 149 PF00069 0.368
MOD_PKB_1 97 105 PF00069 0.627
MOD_Plk_1 137 143 PF00069 0.479
MOD_Plk_4 137 143 PF00069 0.519
MOD_ProDKin_1 48 54 PF00069 0.676
TRG_ER_diArg_1 46 48 PF00400 0.612
TRG_ER_diArg_1 97 100 PF00400 0.659
TRG_Pf-PMV_PEXEL_1 78 83 PF00026 0.477

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IHG6 Leptomonas seymouri 58% 76%
A0A1X0NGS3 Trypanosomatidae 38% 95%
A0A3S7WXM6 Leishmania donovani 81% 72%
A4I062 Leishmania infantum 81% 100%
E9AW25 Leishmania mexicana (strain MHOM/GT/2001/U1103) 77% 71%
Q4QBF2 Leishmania major 79% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS