UPF0147 protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

UPF0147 protein

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HCN3_LEIBR

TriTrypDb:

LbrM.23.0210 , LBRM2903_230007000

Length:

124

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HCN3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HCN3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	74	78	PF00656	0.579
CLV_NRD_NRD_1	43	45	PF00675	0.474
CLV_NRD_NRD_1	67	69	PF00675	0.458
CLV_NRD_NRD_1	85	87	PF00675	0.532
CLV_NRD_NRD_1	90	92	PF00675	0.509
CLV_PCSK_FUR_1	68	72	PF00082	0.559
CLV_PCSK_FUR_1	83	87	PF00082	0.621
CLV_PCSK_FUR_1	88	92	PF00082	0.624
CLV_PCSK_KEX2_1	42	44	PF00082	0.501
CLV_PCSK_KEX2_1	67	69	PF00082	0.474
CLV_PCSK_KEX2_1	70	72	PF00082	0.490
CLV_PCSK_KEX2_1	85	87	PF00082	0.442
CLV_PCSK_KEX2_1	89	91	PF00082	0.365
CLV_PCSK_PC1ET2_1	70	72	PF00082	0.555
CLV_PCSK_PC1ET2_1	87	89	PF00082	0.414
CLV_PCSK_PC7_1	83	89	PF00082	0.542
CLV_PCSK_SKI1_1	24	28	PF00082	0.475
CLV_PCSK_SKI1_1	46	50	PF00082	0.498
DEG_ODPH_VHL_1	14	27	PF01847	0.531
DOC_USP7_MATH_1	96	100	PF00917	0.632
DOC_WW_Pin1_4	112	117	PF00397	0.543
LIG_BIR_II_1	1	5	PF00653	0.531
LIG_Clathr_ClatBox_1	101	105	PF01394	0.672
LIG_FHA_2	50	56	PF00498	0.425
LIG_SUMO_SIM_anti_2	19	24	PF11976	0.534
LIG_SUMO_SIM_par_1	25	31	PF11976	0.442
LIG_SUMO_SIM_par_1	99	105	PF11976	0.666
LIG_TRAF2_1	117	120	PF00917	0.746
LIG_TRAF2_1	16	19	PF00917	0.501
LIG_TRAF2_1	79	82	PF00917	0.590
MOD_CK1_1	112	118	PF00069	0.740
MOD_CK2_1	114	120	PF00069	0.772
MOD_CK2_1	76	82	PF00069	0.581
MOD_Cter_Amidation	68	71	PF01082	0.560
MOD_GlcNHglycan	107	110	PF01048	0.630
MOD_GlcNHglycan	116	119	PF01048	0.660
MOD_GSK3_1	105	112	PF00069	0.664
MOD_GSK3_1	49	56	PF00069	0.531
MOD_PIKK_1	35	41	PF00454	0.346
MOD_Plk_2-3	28	34	PF00069	0.539
MOD_ProDKin_1	112	118	PF00069	0.541
TRG_ER_diArg_1	41	44	PF00400	0.480
TRG_ER_diArg_1	66	68	PF00400	0.475
TRG_ER_diArg_1	83	86	PF00400	0.347
TRG_ER_diArg_1	88	91	PF00400	0.520
TRG_NLS_Bipartite_1	70	91	PF00514	0.568
TRG_NLS_MonoCore_2	85	90	PF00514	0.574
TRG_NLS_MonoExtC_3	85	90	PF00514	0.574
TRG_NLS_MonoExtN_4	83	90	PF00514	0.571

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HV53	Leptomonas seymouri	77%	97%
A0A1X0NGK1	Trypanosomatidae	47%	100%
A0A3R7MXM6	Trypanosoma rangeli	44%	100%
A0A3S7WXL7	Leishmania donovani	85%	99%
A4I057	Leishmania infantum	85%	99%
E9AW20	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	99%
Q4QBF6	Leishmania major	83%	100%