Si:ch211-160o17.6

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Si:ch211-160o17.6

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HCL9_LEIBR

TriTrypDb:

LbrM.23.0070 , LBRM2903_230005500

Length:

173

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HCL9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HCL9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	106	108	PF00675	0.549
CLV_NRD_NRD_1	114	116	PF00675	0.560
CLV_NRD_NRD_1	27	29	PF00675	0.406
CLV_NRD_NRD_1	78	80	PF00675	0.436
CLV_NRD_NRD_1	82	84	PF00675	0.469
CLV_PCSK_FUR_1	76	80	PF00082	0.426
CLV_PCSK_KEX2_1	113	115	PF00082	0.563
CLV_PCSK_KEX2_1	78	80	PF00082	0.388
CLV_PCSK_KEX2_1	82	84	PF00082	0.405
CLV_PCSK_PC1ET2_1	113	115	PF00082	0.563
CLV_PCSK_PC7_1	78	84	PF00082	0.427
CLV_PCSK_SKI1_1	14	18	PF00082	0.563
CLV_PCSK_SKI1_1	19	23	PF00082	0.516
CLV_PCSK_SKI1_1	83	87	PF00082	0.404
DEG_Nend_Nbox_1	1	3	PF02207	0.571
DOC_MAPK_MEF2A_6	162	170	PF00069	0.625
DOC_USP7_MATH_1	147	151	PF00917	0.594
DOC_USP7_MATH_1	45	49	PF00917	0.512
DOC_WW_Pin1_4	127	132	PF00397	0.647
LIG_14-3-3_CanoR_1	138	145	PF00244	0.755
LIG_Actin_WH2_2	64	80	PF00022	0.495
LIG_BRCT_BRCA1_1	150	154	PF00533	0.707
LIG_FHA_1	139	145	PF00498	0.522
LIG_FHA_1	150	156	PF00498	0.691
LIG_FHA_2	18	24	PF00498	0.460
LIG_LIR_Gen_1	161	170	PF02991	0.456
LIG_LIR_Nem_3	161	166	PF02991	0.515
LIG_LIR_Nem_3	8	13	PF02991	0.421
LIG_SH2_CRK	163	167	PF00017	0.456
LIG_SUMO_SIM_par_1	125	130	PF11976	0.602
LIG_TRAF2_1	57	60	PF00917	0.429
LIG_UBA3_1	21	29	PF00899	0.407
MOD_CK1_1	54	60	PF00069	0.416
MOD_CK2_1	127	133	PF00069	0.565
MOD_CK2_1	147	153	PF00069	0.593
MOD_CK2_1	17	23	PF00069	0.423
MOD_CK2_1	54	60	PF00069	0.407
MOD_Cter_Amidation	170	173	PF01082	0.546
MOD_GlcNHglycan	120	123	PF01048	0.581
MOD_GlcNHglycan	158	161	PF01048	0.608
MOD_GlcNHglycan	47	50	PF01048	0.531
MOD_PKA_2	103	109	PF00069	0.499
MOD_PKA_2	137	143	PF00069	0.555
MOD_Plk_4	17	23	PF00069	0.465
MOD_ProDKin_1	127	133	PF00069	0.652
TRG_ENDOCYTIC_2	163	166	PF00928	0.453
TRG_ER_diArg_1	25	28	PF00400	0.397
TRG_ER_diArg_1	76	79	PF00400	0.436
TRG_NLS_MonoExtN_4	111	117	PF00514	0.557
TRG_Pf-PMV_PEXEL_1	28	32	PF00026	0.448
TRG_Pf-PMV_PEXEL_1	7	12	PF00026	0.631

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P4N3	Leptomonas seymouri	60%	100%
A0A0S4J210	Bodo saltans	38%	78%
A0A3S7WXG0	Leishmania donovani	84%	100%
A4I043	Leishmania infantum	84%	100%
C9ZUX9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	93%
E9AW06	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	99%
Q4QBH0	Leishmania major	84%	100%