ATPase_AAA_core domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

mitochondrial chaperone, putative (fragment)

Species:

Leishmania braziliensis

UniProt:

A4HCL1_LEIBR

TriTrypDb:

LbrM.22.1610 , LBRM2903_220013800

Length:

317

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HCL1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HCL1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	107	111	PF00656	0.627
CLV_C14_Caspase3-7	9	13	PF00656	0.480
CLV_NRD_NRD_1	278	280	PF00675	0.583
CLV_NRD_NRD_1	29	31	PF00675	0.521
CLV_NRD_NRD_1	98	100	PF00675	0.761
CLV_PCSK_KEX2_1	102	104	PF00082	0.604
CLV_PCSK_KEX2_1	29	31	PF00082	0.521
CLV_PCSK_KEX2_1	97	99	PF00082	0.656
CLV_PCSK_PC1ET2_1	102	104	PF00082	0.628
CLV_PCSK_PC7_1	25	31	PF00082	0.498
CLV_PCSK_PC7_1	98	104	PF00082	0.662
CLV_PCSK_SKI1_1	118	122	PF00082	0.589
DEG_APCC_DBOX_1	133	141	PF00400	0.489
DEG_APCC_DBOX_1	177	185	PF00400	0.516
DEG_Nend_UBRbox_2	1	3	PF02207	0.520
DOC_CKS1_1	284	289	PF01111	0.400
DOC_CYCLIN_RxL_1	115	122	PF00134	0.564
DOC_MAPK_gen_1	171	181	PF00069	0.441
DOC_MAPK_MEF2A_6	174	181	PF00069	0.528
DOC_PP2B_LxvP_1	148	151	PF13499	0.511
DOC_SPAK_OSR1_1	174	178	PF12202	0.525
DOC_USP7_MATH_1	55	59	PF00917	0.603
DOC_USP7_MATH_1	64	68	PF00917	0.495
DOC_WW_Pin1_4	200	205	PF00397	0.521
DOC_WW_Pin1_4	283	288	PF00397	0.398
LIG_14-3-3_CanoR_1	174	178	PF00244	0.442
LIG_14-3-3_CanoR_1	34	41	PF00244	0.662
LIG_14-3-3_CanoR_1	97	106	PF00244	0.675
LIG_APCC_ABBA_1	5	10	PF00400	0.449
LIG_BIR_III_4	149	153	PF00653	0.451
LIG_EH1_1	120	128	PF00400	0.494
LIG_FHA_1	45	51	PF00498	0.515
LIG_FHA_2	105	111	PF00498	0.631
LIG_FHA_2	284	290	PF00498	0.401
LIG_LIR_Apic_2	163	167	PF02991	0.457
LIG_LIR_Gen_1	182	190	PF02991	0.382
LIG_NRBOX	136	142	PF00104	0.433
LIG_PCNA_PIPBox_1	297	306	PF02747	0.401
LIG_PCNA_yPIPBox_3	297	309	PF02747	0.434
LIG_Rb_pABgroove_1	2	10	PF01858	0.449
LIG_SH2_STAT3	281	284	PF00017	0.417
LIG_SH2_STAT5	281	284	PF00017	0.452
LIG_SUMO_SIM_par_1	154	160	PF11976	0.450
LIG_TRAF2_1	258	261	PF00917	0.550
LIG_TYR_ITIM	195	200	PF00017	0.418
MOD_CDK_SPK_2	200	205	PF00069	0.521
MOD_CK2_1	283	289	PF00069	0.397
MOD_CK2_1	87	93	PF00069	0.681
MOD_GlcNHglycan	219	222	PF01048	0.602
MOD_GlcNHglycan	274	278	PF01048	0.630
MOD_GlcNHglycan	65	69	PF01048	0.652
MOD_GSK3_1	89	96	PF00069	0.681
MOD_NEK2_1	53	58	PF00069	0.551
MOD_NEK2_2	173	178	PF00069	0.596
MOD_PIKK_1	302	308	PF00454	0.381
MOD_PKA_1	97	103	PF00069	0.680
MOD_PKA_2	173	179	PF00069	0.447
MOD_PKA_2	311	317	PF00069	0.497
MOD_PKA_2	33	39	PF00069	0.481
MOD_PKA_2	97	103	PF00069	0.736
MOD_Plk_1	64	70	PF00069	0.554
MOD_ProDKin_1	200	206	PF00069	0.528
MOD_ProDKin_1	283	289	PF00069	0.397
TRG_DiLeu_BaEn_1	185	190	PF01217	0.376
TRG_DiLeu_BaEn_2	1	7	PF01217	0.452
TRG_ENDOCYTIC_2	183	186	PF00928	0.381
TRG_ENDOCYTIC_2	197	200	PF00928	0.415
TRG_ER_diArg_1	177	180	PF00400	0.446
TRG_ER_diArg_1	97	99	PF00400	0.666
TRG_NES_CRM1_1	185	199	PF08389	0.388
TRG_Pf-PMV_PEXEL_1	118	122	PF00026	0.560
TRG_Pf-PMV_PEXEL_1	242	246	PF00026	0.532

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2G7	Leptomonas seymouri	66%	100%
E8NHC6	Leishmania infantum	68%	96%