Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania braziliensis

UniProt:

A4HCJ9_LEIBR

TriTrypDb:

LbrM.22.1470 , LBRM2903_220021500

Length:

330

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HCJ9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HCJ9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	261	265	PF00656	0.701
CLV_NRD_NRD_1	192	194	PF00675	0.578
CLV_NRD_NRD_1	310	312	PF00675	0.609
CLV_NRD_NRD_1	315	317	PF00675	0.589
CLV_PCSK_KEX2_1	192	194	PF00082	0.578
CLV_PCSK_KEX2_1	310	312	PF00082	0.609
CLV_PCSK_KEX2_1	315	317	PF00082	0.589
CLV_PCSK_PC7_1	311	317	PF00082	0.648
CLV_PCSK_SKI1_1	105	109	PF00082	0.740
CLV_PCSK_SKI1_1	127	131	PF00082	0.606
CLV_PCSK_SKI1_1	49	53	PF00082	0.751
DEG_COP1_1	23	31	PF00400	0.578
DOC_CDC14_PxL_1	77	85	PF14671	0.606
DOC_MAPK_MEF2A_6	209	217	PF00069	0.526
DOC_PP1_RVXF_1	254	261	PF00149	0.752
DOC_PP1_SILK_1	293	298	PF00149	0.571
DOC_PP2B_LxvP_1	78	81	PF13499	0.671
DOC_USP7_MATH_1	129	133	PF00917	0.579
DOC_USP7_MATH_1	266	270	PF00917	0.621
DOC_USP7_MATH_1	321	325	PF00917	0.571
DOC_USP7_MATH_2	67	73	PF00917	0.582
DOC_WW_Pin1_4	106	111	PF00397	0.673
DOC_WW_Pin1_4	166	171	PF00397	0.760
DOC_WW_Pin1_4	241	246	PF00397	0.714
DOC_WW_Pin1_4	287	292	PF00397	0.578
LIG_14-3-3_CanoR_1	127	132	PF00244	0.651
LIG_14-3-3_CanoR_1	322	329	PF00244	0.672
LIG_14-3-3_CanoR_1	39	44	PF00244	0.623
LIG_APCC_ABBA_1	205	210	PF00400	0.537
LIG_BIR_II_1	1	5	PF00653	0.612
LIG_FHA_1	202	208	PF00498	0.655
LIG_FHA_1	6	12	PF00498	0.585
LIG_FHA_2	128	134	PF00498	0.750
LIG_FHA_2	139	145	PF00498	0.598
LIG_FHA_2	14	20	PF00498	0.617
LIG_FHA_2	259	265	PF00498	0.706
LIG_LIR_Gen_1	226	235	PF02991	0.539
LIG_LIR_Gen_1	257	267	PF02991	0.736
LIG_LIR_Nem_3	226	231	PF02991	0.530
LIG_LIR_Nem_3	257	263	PF02991	0.745
LIG_LIR_Nem_3	264	270	PF02991	0.605
LIG_MYND_1	106	110	PF01753	0.576
LIG_PCNA_PIPBox_1	224	233	PF02747	0.723
LIG_SH2_CRK	267	271	PF00017	0.526
LIG_SH2_NCK_1	41	45	PF00017	0.535
LIG_SH2_STAT5	41	44	PF00017	0.599
LIG_SH3_1	148	154	PF00018	0.594
LIG_SH3_3	111	117	PF00018	0.569
LIG_SH3_3	148	154	PF00018	0.675
LIG_SH3_3	15	21	PF00018	0.799
LIG_SH3_3	297	303	PF00018	0.732
LIG_SH3_3	92	98	PF00018	0.555
LIG_SUMO_SIM_anti_2	99	105	PF11976	0.560
LIG_TRAF2_1	162	165	PF00917	0.590
LIG_WRC_WIRS_1	306	311	PF05994	0.546
LIG_WW_3	73	77	PF00397	0.585
MOD_CDC14_SPxK_1	109	112	PF00782	0.573
MOD_CDC14_SPxK_1	169	172	PF00782	0.737
MOD_CDC14_SPxK_1	244	247	PF00782	0.592
MOD_CDK_SPxK_1	106	112	PF00069	0.575
MOD_CDK_SPxK_1	166	172	PF00069	0.738
MOD_CDK_SPxK_1	241	247	PF00069	0.591
MOD_CK1_1	125	131	PF00069	0.652
MOD_CK1_1	290	296	PF00069	0.694
MOD_CK1_1	55	61	PF00069	0.685
MOD_CK2_1	127	133	PF00069	0.749
MOD_CK2_1	13	19	PF00069	0.596
MOD_CK2_1	138	144	PF00069	0.595
MOD_CK2_1	271	277	PF00069	0.549
MOD_CK2_1	278	284	PF00069	0.568
MOD_GlcNHglycan	280	283	PF01048	0.690
MOD_GlcNHglycan	292	295	PF01048	0.608
MOD_GSK3_1	121	128	PF00069	0.618
MOD_GSK3_1	193	200	PF00069	0.725
MOD_GSK3_1	216	223	PF00069	0.603
MOD_GSK3_1	230	237	PF00069	0.520
MOD_GSK3_1	252	259	PF00069	0.708
MOD_GSK3_1	278	285	PF00069	0.739
MOD_GSK3_1	35	42	PF00069	0.637
MOD_GSK3_1	5	12	PF00069	0.640
MOD_N-GLC_2	157	159	PF02516	0.606
MOD_NEK2_1	138	143	PF00069	0.721
MOD_NEK2_1	213	218	PF00069	0.590
MOD_NEK2_1	240	245	PF00069	0.721
MOD_NEK2_1	258	263	PF00069	0.717
MOD_NEK2_1	37	42	PF00069	0.546
MOD_NEK2_1	60	65	PF00069	0.589
MOD_NEK2_2	305	310	PF00069	0.533
MOD_PIKK_1	13	19	PF00454	0.616
MOD_PIKK_1	220	226	PF00454	0.706
MOD_PIKK_1	230	236	PF00454	0.580
MOD_PKA_2	321	327	PF00069	0.689
MOD_Plk_1	138	144	PF00069	0.746
MOD_Plk_1	211	217	PF00069	0.544
MOD_Plk_1	256	262	PF00069	0.739
MOD_Plk_1	271	277	PF00069	0.511
MOD_Plk_4	213	219	PF00069	0.715
MOD_Plk_4	99	105	PF00069	0.560
MOD_ProDKin_1	106	112	PF00069	0.674
MOD_ProDKin_1	166	172	PF00069	0.762
MOD_ProDKin_1	241	247	PF00069	0.714
MOD_ProDKin_1	287	293	PF00069	0.579
TRG_DiLeu_BaLyEn_6	73	78	PF01217	0.680
TRG_ENDOCYTIC_2	184	187	PF00928	0.562
TRG_ENDOCYTIC_2	267	270	PF00928	0.527
TRG_ENDOCYTIC_2	34	37	PF00928	0.647
TRG_ER_diArg_1	192	194	PF00400	0.578
TRG_ER_diArg_1	309	311	PF00400	0.671
TRG_ER_diArg_1	315	318	PF00400	0.651

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I3L3	Leptomonas seymouri	36%	100%
A0A3S7WXD1	Leishmania donovani	55%	100%