Ca2+-binding EF-hand protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

centrin-4, putative

Species:

Leishmania braziliensis

UniProt:

A4HCI2_LEIBR

TriTrypDb:

LbrM.22.1290 , LBRM2903_220019500

Length:

149

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 3
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 16

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 21

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005813	centrosome	3	1
GO:0005814	centriole	5	1
GO:0005815	microtubule organizing center	2	2
GO:0036064	ciliary basal body	3	1
GO:0043226	organelle	2	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

A4HCI2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HCI2

Function

Biological processes
Term	Name	Level	Count
GO:0000278	mitotic cell cycle	3	1
GO:0006996	organelle organization	4	1
GO:0007017	microtubule-based process	2	1
GO:0007049	cell cycle	2	1
GO:0007099	centriole replication	3	1
GO:0009987	cellular process	1	1
GO:0010564	regulation of cell cycle process	5	1
GO:0016043	cellular component organization	3	1
GO:0022402	cell cycle process	2	1
GO:0022607	cellular component assembly	4	1
GO:0031023	microtubule organizing center organization	3	1
GO:0032465	regulation of cytokinesis	5	1
GO:0033043	regulation of organelle organization	5	1
GO:0050789	regulation of biological process	2	1
GO:0050794	regulation of cellular process	3	1
GO:0051128	regulation of cellular component organization	4	1
GO:0051302	regulation of cell division	4	1
GO:0051726	regulation of cell cycle	4	1
GO:0051783	regulation of nuclear division	6	1
GO:0065007	biological regulation	1	1
GO:0070925	organelle assembly	5	1
GO:0071840	cellular component organization or biogenesis	2	1
GO:0098534	centriole assembly	4	1
GO:0140694	non-membrane-bounded organelle assembly	6	1
GO:1902412	regulation of mitotic cytokinesis	6	1

Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	12
GO:0005509	calcium ion binding	5	12
GO:0043167	ion binding	2	12
GO:0043169	cation binding	3	12
GO:0046872	metal ion binding	4	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	128	132	PF00656	0.278
CLV_PCSK_SKI1_1	10	14	PF00082	0.244
DOC_CYCLIN_RxL_1	31	40	PF00134	0.245
DOC_MAPK_gen_1	94	100	PF00069	0.259
DOC_PP1_RVXF_1	32	39	PF00149	0.244
DOC_PP1_RVXF_1	95	101	PF00149	0.244
DOC_USP7_MATH_1	18	22	PF00917	0.264
DOC_USP7_UBL2_3	104	108	PF12436	0.253
DOC_WW_Pin1_4	76	81	PF00397	0.461
LIG_14-3-3_CanoR_1	48	54	PF00244	0.259
LIG_BIR_II_1	1	5	PF00653	0.449
LIG_BIR_III_4	17	21	PF00653	0.259
LIG_BIR_III_4	56	60	PF00653	0.218
LIG_Clathr_ClatBox_1	89	93	PF01394	0.259
LIG_LIR_Gen_1	11	18	PF02991	0.244
LIG_LIR_Gen_1	133	144	PF02991	0.310
LIG_LIR_Gen_1	99	107	PF02991	0.259
LIG_LIR_Nem_3	11	16	PF02991	0.244
LIG_LIR_Nem_3	133	139	PF02991	0.310
LIG_LIR_Nem_3	62	66	PF02991	0.163
LIG_LIR_Nem_3	99	103	PF02991	0.244
LIG_TRAF2_1	135	138	PF00917	0.278
LIG_TRAF2_1	79	82	PF00917	0.390
LIG_UBA3_1	143	149	PF00899	0.447
LIG_UBA3_1	89	97	PF00899	0.259
MOD_CK2_1	132	138	PF00069	0.291
MOD_CK2_1	76	82	PF00069	0.451
MOD_GlcNHglycan	19	23	PF01048	0.258
MOD_NEK2_1	69	74	PF00069	0.485
MOD_Plk_1	132	138	PF00069	0.278
MOD_Plk_4	138	144	PF00069	0.303
MOD_ProDKin_1	76	82	PF00069	0.456
MOD_SUMO_rev_2	133	142	PF00179	0.278
TRG_DiLeu_BaEn_1	105	110	PF01217	0.259
TRG_ENDOCYTIC_2	63	66	PF00928	0.346
TRG_NES_CRM1_1	81	93	PF08389	0.261
TRG_Pf-PMV_PEXEL_1	108	112	PF00026	0.258

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P206	Leptomonas seymouri	40%	100%
A0A0N0P419	Leptomonas seymouri	32%	85%
A0A0N0P4B4	Leptomonas seymouri	26%	100%
A0A0N0P7N1	Leptomonas seymouri	33%	71%
A0A0N0P8Y6	Leptomonas seymouri	45%	82%
A0A0N1I2Q3	Leptomonas seymouri	96%	100%
A0A0N1IMR9	Leptomonas seymouri	32%	90%
A0A0N1PB14	Leptomonas seymouri	45%	71%
A0A0N1PB23	Leptomonas seymouri	32%	96%
A0A0N1PDC0	Leptomonas seymouri	24%	97%
A0A0S4ILD1	Bodo saltans	38%	85%
A0A0S4INC8	Bodo saltans	47%	80%
A0A0S4IS38	Bodo saltans	40%	100%
A0A0S4IXG9	Bodo saltans	26%	100%
A0A0S4J2T4	Bodo saltans	35%	87%
A0A0S4J7U6	Bodo saltans	56%	92%
A0A0S4J9K1	Bodo saltans	27%	85%
A0A0S4JFC8	Bodo saltans	40%	88%
A0A0S4JFY6	Bodo saltans	31%	100%
A0A0S4JGV2	Bodo saltans	26%	96%
A0A0S4JK78	Bodo saltans	26%	94%
A0A0S4JTP8	Bodo saltans	32%	99%
A0A0S4KIF8	Bodo saltans	31%	75%
A0A0S4KL65	Bodo saltans	24%	100%
A0A1X0NEW2	Trypanosomatidae	51%	78%
A0A1X0NM23	Trypanosomatidae	35%	90%
A0A1X0NMM5	Trypanosomatidae	40%	100%
A0A1X0NTH2	Trypanosomatidae	91%	100%
A0A1X0NVB5	Trypanosomatidae	34%	80%
A0A1X0P3L8	Trypanosomatidae	34%	98%
A0A1X0P607	Trypanosomatidae	26%	100%
A0A1X0P9X3	Trypanosomatidae	46%	82%
A0A3Q8ICY9	Leishmania donovani	32%	71%
A0A3Q8IHK5	Leishmania donovani	45%	82%
A0A3Q8IPV4	Leishmania donovani	34%	90%
A0A3Q8IW81	Leishmania donovani	28%	96%
A0A3R7K2E4	Trypanosoma rangeli	32%	98%
A0A3R7KFP2	Trypanosoma rangeli	33%	70%
A0A3R7M547	Trypanosoma rangeli	91%	100%
A0A3R7NPA6	Trypanosoma rangeli	34%	80%
A0A3S7WPW7	Leishmania donovani	46%	80%
A0A3S7WWS9	Leishmania donovani	30%	85%
A0A3S7WXD9	Leishmania donovani	95%	100%
A0A3S7X1A1	Leishmania donovani	29%	97%
A0A3S7X9Z4	Leishmania donovani	27%	100%
A0A422MQ47	Trypanosoma rangeli	40%	100%
A0A422N1V6	Trypanosoma rangeli	26%	88%
A0A422N447	Trypanosoma rangeli	27%	100%
A0A422N487	Trypanosoma rangeli	90%	100%
A0A422N5Z1	Trypanosoma rangeli	50%	78%
A0A422N8B8	Trypanosoma rangeli	25%	85%
A0A422NL71	Trypanosoma rangeli	26%	96%
A0A422P0I1	Trypanosoma rangeli	46%	82%
A0T2M3	Hesperocyparis arizonica	32%	90%
A2WN93	Oryza sativa subsp. indica	42%	100%
A2WNH1	Oryza sativa subsp. indica	41%	100%
A2Y609	Oryza sativa subsp. indica	42%	100%
A3E3H0	Pfiesteria piscicida	40%	100%
A3E4D8	Prorocentrum minimum	40%	100%
A3E4F9	Karlodinium veneficum	40%	100%
A4H522	Leishmania braziliensis	45%	100%
A4H5R9	Leishmania braziliensis	40%	100%
A4HAV0	Leishmania braziliensis	45%	100%
A4HC25	Leishmania braziliensis	30%	100%
A4HK46	Leishmania braziliensis	31%	71%
A4HN60	Leishmania braziliensis	25%	100%
A4HPN5	Leishmania braziliensis	30%	96%
A4HQD0	Leishmania braziliensis	34%	90%
A4HT95	Leishmania infantum	46%	80%
A4HU13	Leishmania infantum	40%	100%
A4HZG8	Leishmania infantum	30%	85%
A4I000	Leishmania infantum	95%	100%
A4I3F5	Leishmania infantum	29%	97%
A4I7L6	Leishmania infantum	32%	71%
A4IA04	Leishmania infantum	45%	82%
A4IBS7	Leishmania infantum	27%	100%
A4ID29	Leishmania infantum	29%	96%
A4IE23	Leishmania infantum	34%	90%
A4IF97	Bos taurus	26%	87%
A4UHC0	Alexandrium fundyense	40%	100%
A8CEP3	Saccharina japonica	42%	100%
A8I1Q0	Heterocapsa triquetra	40%	100%
A8J3A0	Chlamydomonas reinhardtii	28%	90%
B1PSN3	Leishmania donovani	40%	100%
C9ZML6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	47%	82%
C9ZSQ3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	92%	100%
C9ZUM6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	48%	76%
D0A3W9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	90%
D0A6K2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	96%
D0A8H8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	91%
D0A9H8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	100%
D0A9H9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
D0A9T3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	80%
D2DGW3	Tyrophagus putrescentiae	31%	97%
E9AL84	Leishmania mexicana (strain MHOM/GT/2001/U1103)	47%	80%
E9AMU3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	100%
E9ATE9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	70%
E9AU46	Leishmania mexicana (strain MHOM/GT/2001/U1103)	34%	90%
E9AVF8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	85%
E9AVX3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	95%	100%
E9AZP3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	97%
E9B2I9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	71%
E9B525	Leishmania mexicana (strain MHOM/GT/2001/U1103)	45%	82%
E9B6R7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
G5EDN6	Caenorhabditis elegans	31%	87%
J9W034	Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487)	43%	86%
O00897	Dictyostelium discoideum	30%	100%
O01305	Branchiostoma floridae	30%	92%
O02367	Ciona intestinalis	43%	100%
O14008	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	27%	100%
O14950	Homo sapiens	26%	87%
O15182	Homo sapiens	45%	89%
O16305	Caenorhabditis elegans	43%	100%
O22845	Arabidopsis thaliana	32%	69%
O23184	Arabidopsis thaliana	43%	89%
O23320	Arabidopsis thaliana	39%	99%
O35648	Mus musculus	45%	89%
O43745	Homo sapiens	27%	76%
O60041	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	38%	100%
O64943	Juniperus oxycedrus	33%	90%
O74435	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	42%	85%
O82018	Mougeotia scalaris	41%	100%
O82659	Arabidopsis thaliana	45%	88%
O94739	Pleurotus ostreatus	42%	100%
O96081	Halocynthia roretzi	43%	100%
O96102	Physarum polycephalum	43%	100%
O97341	Suberites domuncula	44%	100%
P02585	Homo sapiens	32%	93%
P02586	Oryctolagus cuniculus	32%	93%
P02587	Sus scrofa	32%	94%
P02588	Gallus gallus	29%	91%
P02589	Pelophylax lessonae	33%	92%
P02591	Oryctolagus cuniculus	30%	93%
P02594	Electrophorus electricus	43%	100%
P02595	Patinopecten sp.	43%	100%
P02597	Gallus gallus	39%	100%
P02598	Tetrahymena pyriformis	40%	100%
P02599	Dictyostelium discoideum	41%	98%
P02607	Gallus gallus	26%	99%
P02611	Gallus gallus	24%	90%
P02612	Gallus gallus	26%	87%
P04111	Strongylocentrotus purpuratus	26%	99%
P04352	Chlamydomonas reinhardtii	40%	91%
P04353	Spinacia oleracea	42%	100%
P04464	Triticum aestivum	42%	100%
P04630	Caenorhabditis elegans	39%	93%
P05419	Gallus gallus	42%	100%
P05434	Chlamydomonas reinhardtii	48%	88%
P05932	Arbacia punctulata	42%	100%
P05933	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	39%	99%
P05936	Coturnix japonica	29%	93%
P05945	Todarodes pacificus	32%	93%
P06704	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	43%	93%
P06706	Halocynthia roretzi	33%	96%
P06707	Astacus leptodactylus	29%	99%
P06708	Astacus leptodactylus	28%	99%
P06787	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	35%	100%
P07461	Halocynthia roretzi	33%	97%
P07462	Halocynthia roretzi	24%	99%
P07463	Paramecium tetraurelia	42%	100%
P08051	Spisula sachalinensis	27%	93%
P08053	Physarum polycephalum	25%	100%
P08733	Rattus norvegicus	22%	90%
P09860	Gallus gallus	29%	93%
P0CM54	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	32%	85%
P0CM55	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	32%	85%
P0DH95	Arabidopsis thaliana	42%	100%
P0DH96	Arabidopsis thaliana	42%	100%
P0DH97	Arabidopsis thaliana	42%	100%
P0DH98	Arabidopsis thaliana	42%	100%
P0DP23	Homo sapiens	43%	100%
P0DP24	Homo sapiens	43%	100%
P0DP25	Homo sapiens	43%	100%
P0DP26	Mus musculus	43%	100%
P0DP27	Mus musculus	43%	100%
P0DP28	Mus musculus	43%	100%
P0DP29	Rattus norvegicus	43%	100%
P0DP30	Rattus norvegicus	43%	100%
P0DP31	Rattus norvegicus	43%	100%
P0DP33	Xenopus laevis	43%	100%
P0DP34	Xenopus laevis	43%	100%
P0DP35	Xenopus laevis	43%	100%
P10246	Meleagris gallopavo	32%	92%
P10916	Homo sapiens	22%	90%
P11118	Euglena gracilis	41%	100%
P11120	Pleurotus cornucopiae	42%	100%
P11121	Pyuridae sp.	43%	100%
P13832	Rattus norvegicus	25%	87%
P13833	Dictyostelium discoideum	24%	93%
P13868	Solanum tuberosum	42%	100%
P14533	Doryteuthis pealeii	42%	100%
P14649	Homo sapiens	27%	72%
P15094	Achlya klebsiana	42%	100%
P15159	Tachypleus tridentatus	31%	97%
P15845	Schistosoma mansoni	25%	97%
P17928	Medicago sativa	42%	100%
P18061	Trypanosoma cruzi	40%	100%
P18666	Rattus norvegicus	26%	87%
P19105	Homo sapiens	26%	87%
P19123	Mus musculus	30%	93%
P20801	Mus musculus	32%	93%
P21251	Stichopus japonicus	43%	100%
P21797	Balanus nubilus	30%	94%
P21798	Balanus nubilus	30%	99%
P23286	Candida albicans	35%	100%
P24032	Gallus gallus	26%	87%
P24044	Plasmodium falciparum	39%	100%
P24844	Homo sapiens	26%	87%
P25070	Arabidopsis thaliana	31%	93%
P25296	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	33%	85%
P27161	Solanum lycopersicum	42%	100%
P27163	Petunia hybrida	42%	100%
P27164	Petunia hybrida	41%	81%
P27165	Phytophthora infestans	42%	100%
P27166	Stylonychia lemnae	40%	100%
P27482	Homo sapiens	40%	100%
P28470	Rattus norvegicus	32%	85%
P29269	Sus scrofa	26%	87%
P29289	Homarus americanus	28%	99%
P29290	Homarus americanus	28%	99%
P29291	Homarus americanus	28%	99%
P30187	Arabidopsis thaliana	34%	78%
P30188	Arabidopsis thaliana	28%	69%
P30644	Caenorhabditis elegans	33%	100%
P35622	Mizuhopecten yessoensis	27%	98%
P41040	Zea mays	42%	100%
P41041	Pneumocystis carinii	42%	99%
P41208	Homo sapiens	53%	87%
P41209	Mus musculus	52%	87%
P41210	Atriplex nummularia	42%	89%
P42322	Naegleria gruberi	33%	84%
P43187	Betula pendula	28%	73%
P43645	Spermatozopsis similis	50%	100%
P43646	Tetraselmis striata	54%	100%
P47947	Drosophila melanogaster	32%	97%
P47948	Drosophila melanogaster	32%	96%
P47949	Drosophila melanogaster	34%	96%
P48451	Drosophila melanogaster	32%	88%
P48593	Drosophila melanogaster	26%	77%
P48976	Malus domestica	41%	100%
P49258	Drosophila melanogaster	37%	100%
P51667	Mus musculus	22%	90%
P53141	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	31%	100%
P53440	Naegleria gruberi	40%	96%
P53441	Naegleria gruberi	48%	87%
P54213	Dunaliella salina	47%	88%
P54357	Drosophila melanogaster	30%	100%
P59220	Arabidopsis thaliana	42%	100%
P60204	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	41%	100%
P60205	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	41%	100%
P60206	Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC 2432)	41%	100%
P61859	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	41%	100%
P61860	Colletotrichum trifolii	41%	100%
P61861	Colletotrichum gloeosporioides	41%	100%
P62144	Anas platyrhynchos	43%	100%
P62145	Aplysia californica	43%	100%
P62146	Arbacia punctulata	44%	100%
P62147	Branchiostoma floridae	43%	100%
P62148	Branchiostoma lanceolatum	43%	100%
P62149	Gallus gallus	43%	100%
P62150	Oryzias latipes	42%	100%
P62151	Tetronarce californica	43%	100%
P62152	Drosophila melanogaster	43%	100%
P62153	Halocynthia roretzi	43%	100%
P62154	Locusta migratoria	43%	100%
P62156	Oncorhynchus sp.	43%	100%
P62157	Bos taurus	43%	100%
P62160	Oryctolagus cuniculus	43%	100%
P62162	Hordeum vulgare	42%	100%
P62163	Glycine max	42%	100%
P62184	Renilla reniformis	43%	100%
P62199	Petunia hybrida	42%	100%
P62200	Daucus carota	42%	100%
P62201	Lilium longiflorum	42%	100%
P62202	Bryonia dioica	42%	100%
P62203	Plasmodium falciparum (isolate 3D7)	39%	100%
P63098	Homo sapiens	34%	88%
P63099	Bos taurus	34%	88%
P63100	Rattus norvegicus	34%	88%
P63315	Bos taurus	30%	93%
P63316	Homo sapiens	30%	93%
P63317	Sus scrofa	30%	93%
P69097	Trypanosoma brucei brucei	40%	100%
P69098	Trypanosoma brucei gambiense	40%	100%
P80322	Branchiostoma lanceolatum	30%	91%
P81660	Anguilla anguilla	30%	93%
P84339	Agaricus bisporus	43%	100%
P87072	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	30%	86%
P93087	Capsicum annuum	41%	100%
P93171	Helianthus annuus	41%	100%
Q03509	Arabidopsis thaliana	42%	100%
Q06827	Scherffelia dubia	54%	89%
Q07167	Schistosoma mansoni	24%	100%
Q09011	Solanum tuberosum	27%	75%
Q09510	Caenorhabditis elegans	27%	87%
Q09665	Caenorhabditis elegans	33%	93%
Q0DJ94	Oryza sativa subsp. japonica	30%	76%
Q0DJV6	Oryza sativa subsp. japonica	34%	94%
Q0DZP5	Oryza sativa subsp. japonica	30%	91%
Q0IQB6	Oryza sativa subsp. japonica	36%	81%
Q0IUU4	Oryza sativa subsp. japonica	37%	81%
Q0JNL7	Oryza sativa subsp. japonica	41%	100%
Q0JNS6	Oryza sativa subsp. japonica	42%	100%
Q10LX4	Oryza sativa subsp. japonica	31%	78%
Q12798	Homo sapiens	52%	87%
Q17133	Branchiostoma floridae	28%	100%
Q1A7B1	Blattella germanica	34%	97%
Q1A7B2	Blattella germanica	32%	99%
Q1A7B3	Blattella germanica	32%	99%
Q24214	Drosophila melanogaster	31%	88%
Q24956	Giardia intestinalis	47%	85%
Q27177	Paramecium tetraurelia	39%	82%
Q27178	Paramecium tetraurelia	40%	81%
Q27179	Paramecium tetraurelia	40%	82%
Q2QVI1	Oryza sativa subsp. japonica	28%	87%
Q2R1Z5	Oryza sativa subsp. japonica	36%	88%
Q2TBI5	Bos taurus	31%	88%
Q2TBN3	Bos taurus	52%	87%
Q32LE3	Bos taurus	54%	87%
Q338P8	Oryza sativa subsp. japonica	40%	78%
Q39584	Chlamydomonas reinhardtii	32%	94%
Q39752	Fagus sylvatica	42%	100%
Q3SB08	Pseudechis porphyriacus	32%	96%
Q3SB09	Pseudechis australis	32%	96%
Q3SB10	Hoplocephalus stephensii	32%	96%
Q3SB11	Tropidechis carinatus	32%	96%
Q3SB12	Notechis scutatus scutatus	32%	96%
Q3SB13	Pseudonaja textilis	32%	96%
Q3SB14	Oxyuranus microlepidotus	32%	96%
Q3SB15	Oxyuranus scutellatus scutellatus	32%	96%
Q3SEK0	Paramecium tetraurelia	35%	86%
Q3SEK2	Paramecium tetraurelia	40%	81%
Q3SZE5	Bos taurus	22%	90%
Q3T0E8	Bos taurus	30%	97%
Q3THE2	Mus musculus	26%	87%
Q40302	Macrocystis pyrifera	42%	100%
Q40642	Oryza sativa subsp. indica	41%	80%
Q41420	Solanum tuberosum	34%	100%
Q4Q0E9	Leishmania major	35%	100%
Q4Q148	Leishmania major	31%	100%
Q4Q2W1	Leishmania major	45%	100%
Q4Q5L7	Leishmania major	32%	71%
Q4Q8I9	Leishmania major	27%	100%
Q4QBK6	Leishmania major	95%	100%
Q4QC21	Leishmania major	30%	100%
Q4QHT2	Leishmania major	40%	100%
Q4QIM0	Leishmania major	46%	100%
Q54IY3	Dictyostelium discoideum	31%	99%
Q54X77	Dictyostelium discoideum	33%	99%
Q55G87	Dictyostelium discoideum	32%	83%
Q568G4	Danio rerio	25%	89%
Q5E9E2	Bos taurus	26%	87%
Q5RAD2	Pongo abelii	43%	100%
Q5RBA4	Pongo abelii	26%	87%
Q5RC34	Pongo abelii	26%	87%
Q5U206	Rattus norvegicus	41%	100%
Q5XGC7	Xenopus tropicalis	28%	97%
Q5ZCK5	Oryza sativa subsp. japonica	33%	82%
Q62082	Mus musculus	24%	74%
Q63810	Mus musculus	34%	88%
Q63811	Mus musculus	33%	83%
Q64119	Rattus norvegicus	26%	99%
Q64122	Rattus norvegicus	26%	87%
Q682T9	Arabidopsis thaliana	42%	100%
Q6AXQ2	Rattus norvegicus	29%	92%
Q6BWS8	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	35%	86%
Q6CGE6	Yarrowia lipolytica (strain CLIB 122 / E 150)	30%	86%
Q6F332	Oryza sativa subsp. japonica	42%	100%
Q6F334	Oryza sativa subsp. japonica	29%	96%
Q6FLU4	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	36%	85%
Q6IT78	Ctenopharyngodon idella	43%	100%
Q6L4D4	Oryza sativa subsp. japonica	32%	74%
Q6L5F4	Oryza sativa subsp. japonica	34%	86%
Q6PI52	Danio rerio	43%	100%
Q6R520	Oreochromis mossambicus	43%	100%
Q6YNX6	Ovis aries	43%	100%
Q71UH5	Globisporangium splendens	42%	100%
Q71UH6	Perca flavescens	43%	100%
Q757B7	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	34%	85%
Q7DMN9	Solanum tuberosum	40%	100%
Q7DMP0	Solanum tuberosum	37%	100%
Q7F0J0	Oryza sativa subsp. japonica	43%	88%
Q7M2V4	Oryctolagus cuniculus	23%	90%
Q7T3T2	Epinephelus akaara	43%	100%
Q7XHW4	Oryza sativa subsp. japonica	31%	76%
Q7Y052	Euphorbia characias	42%	100%
Q7Z2B8	Dictyostelium discoideum	29%	100%
Q84MN0	Oryza sativa subsp. japonica	40%	97%
Q84UL5	Oryza sativa subsp. japonica	30%	76%
Q84VG0	Oryza sativa subsp. japonica	28%	100%
Q874T7	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	33%	85%
Q8AY75	Bothrops insularis	32%	96%
Q8CI43	Mus musculus	27%	72%
Q8K4K1	Mus musculus	48%	89%
Q8L3R2	Arabidopsis thaliana	28%	73%
Q8RYJ8	Oryza sativa subsp. japonica	34%	100%
Q8RYJ9	Oryza sativa subsp. japonica	27%	99%
Q8RYK0	Oryza sativa subsp. japonica	28%	99%
Q8RZB5	Oryza sativa subsp. japonica	34%	81%
Q8S1Y9	Oryza sativa subsp. japonica	41%	80%
Q8STF0	Strongylocentrotus intermedius	43%	96%
Q8TD86	Homo sapiens	30%	82%
Q8VZ50	Arabidopsis thaliana	26%	100%
Q8X187	Paxillus involutus	42%	100%
Q91WQ9	Mus musculus	30%	97%
Q94726	Paramecium tetraurelia	40%	82%
Q948R0	Oryza sativa subsp. japonica	36%	90%
Q94AZ4	Arabidopsis thaliana	26%	100%
Q95NI4	Halichondria okadai	43%	100%
Q95NR9	Metridium senile	43%	100%
Q96GE6	Homo sapiens	32%	76%
Q96LZ3	Homo sapiens	34%	88%
Q9AWK2	Oryza sativa subsp. japonica	32%	71%
Q9BLG0	Todarodes pacificus	30%	100%
Q9BUY7	Homo sapiens	25%	91%
Q9C8Y1	Arabidopsis thaliana	31%	95%
Q9C9U8	Arabidopsis thaliana	32%	91%
Q9CQ19	Mus musculus	26%	87%
Q9D6P8	Mus musculus	41%	100%
Q9FI19	Arabidopsis thaliana	32%	82%
Q9FIH9	Arabidopsis thaliana	30%	81%
Q9FYK2	Arabidopsis thaliana	34%	80%
Q9FZ75	Arabidopsis thaliana	33%	95%
Q9GRJ1	Lumbricus rubellus	43%	100%
Q9HFY6	Blastocladiella emersonii	42%	100%
Q9JLK3	Mus musculus	31%	86%
Q9JLK4	Mus musculus	33%	69%
Q9JM83	Mus musculus	34%	100%
Q9LE22	Arabidopsis thaliana	34%	88%
Q9LF55	Arabidopsis thaliana	30%	100%
Q9LI84	Arabidopsis thaliana	31%	93%
Q9LIK5	Arabidopsis thaliana	39%	86%
Q9LNE7	Arabidopsis thaliana	33%	99%
Q9LPK5	Arabidopsis thaliana	28%	96%
Q9LQN4	Arabidopsis thaliana	35%	90%
Q9LX27	Arabidopsis thaliana	33%	76%
Q9M7R0	Olea europaea	36%	87%
Q9M8U1	Arabidopsis thaliana	34%	90%
Q9N1Q8	Bos taurus	31%	86%
Q9N1Q9	Bos taurus	31%	91%
Q9NP86	Homo sapiens	31%	86%
Q9NPB3	Homo sapiens	31%	68%
Q9NZT1	Homo sapiens	33%	100%
Q9R1K9	Mus musculus	51%	87%
Q9S744	Arabidopsis thaliana	32%	99%
Q9SJN6	Arabidopsis thaliana	31%	100%
Q9SRE6	Arabidopsis thaliana	29%	84%
Q9SRE7	Arabidopsis thaliana	30%	94%
Q9SRP4	Arabidopsis thaliana	27%	100%
Q9SRR7	Arabidopsis thaliana	30%	97%
Q9SS31	Arabidopsis thaliana	33%	71%
Q9SU00	Arabidopsis thaliana	30%	98%
Q9SVG9	Arabidopsis thaliana	29%	78%
Q9U6D3	Myxine glutinosa	43%	100%
Q9UB37	Branchiostoma lanceolatum	43%	100%
Q9UU93	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	32%	86%
Q9UWF0	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	41%	100%
Q9XZP2	Branchiostoma floridae	43%	100%
Q9ZQE6	Arabidopsis thaliana	30%	80%
Q9ZR02	Arabidopsis thaliana	32%	97%
V5BNS7	Trypanosoma cruzi	35%	90%
V5DQ66	Trypanosoma cruzi	50%	79%