LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:
Uncharacterized protein
Gene product:
WD domain, G-beta repeat, putative
Species:
Leishmania braziliensis
UniProt:
A4HCG0_LEIBR
TriTrypDb:
LbrM.22.1090 , LBRM2903_220016600 *
Length:
770

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HCG0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HCG0

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 290 294 PF00656 0.844
CLV_C14_Caspase3-7 505 509 PF00656 0.853
CLV_C14_Caspase3-7 637 641 PF00656 0.735
CLV_NRD_NRD_1 130 132 PF00675 0.733
CLV_NRD_NRD_1 344 346 PF00675 0.890
CLV_NRD_NRD_1 445 447 PF00675 0.872
CLV_NRD_NRD_1 714 716 PF00675 0.845
CLV_NRD_NRD_1 717 719 PF00675 0.792
CLV_NRD_NRD_1 759 761 PF00675 0.853
CLV_NRD_NRD_1 762 764 PF00675 0.798
CLV_PCSK_FUR_1 442 446 PF00082 0.868
CLV_PCSK_FUR_1 715 719 PF00082 0.848
CLV_PCSK_FUR_1 760 764 PF00082 0.847
CLV_PCSK_KEX2_1 130 132 PF00082 0.733
CLV_PCSK_KEX2_1 344 346 PF00082 0.890
CLV_PCSK_KEX2_1 425 427 PF00082 0.866
CLV_PCSK_KEX2_1 444 446 PF00082 0.533
CLV_PCSK_KEX2_1 716 718 PF00082 0.852
CLV_PCSK_KEX2_1 729 731 PF00082 0.589
CLV_PCSK_KEX2_1 759 761 PF00082 0.853
CLV_PCSK_KEX2_1 762 764 PF00082 0.798
CLV_PCSK_PC1ET2_1 425 427 PF00082 0.866
CLV_PCSK_PC1ET2_1 716 718 PF00082 0.852
CLV_PCSK_PC1ET2_1 729 731 PF00082 0.589
CLV_PCSK_SKI1_1 123 127 PF00082 0.728
CLV_PCSK_SKI1_1 157 161 PF00082 0.765
CLV_PCSK_SKI1_1 34 38 PF00082 0.718
CLV_PCSK_SKI1_1 426 430 PF00082 0.867
CLV_PCSK_SKI1_1 548 552 PF00082 0.822
DEG_APCC_DBOX_1 33 41 PF00400 0.724
DEG_SCF_FBW7_1 232 238 PF00400 0.868
DEG_SCF_FBW7_1 250 256 PF00400 0.566
DEG_SPOP_SBC_1 187 191 PF00917 0.843
DEG_SPOP_SBC_1 217 221 PF00917 0.861
DEG_SPOP_SBC_1 236 240 PF00917 0.535
DEG_SPOP_SBC_1 554 558 PF00917 0.854
DEG_SPOP_SBC_1 576 580 PF00917 0.838
DEG_SPOP_SBC_1 73 77 PF00917 0.885
DEG_SPOP_SBC_1 94 98 PF00917 0.835
DOC_CKS1_1 232 237 PF01111 0.867
DOC_CKS1_1 250 255 PF01111 0.566
DOC_CKS1_1 303 308 PF01111 0.866
DOC_CKS1_1 517 522 PF01111 0.865
DOC_CYCLIN_yCln2_LP_2 106 112 PF00134 0.785
DOC_CYCLIN_yCln2_LP_2 160 166 PF00134 0.756
DOC_PP1_RVXF_1 737 743 PF00149 0.801
DOC_PP2B_LxvP_1 208 211 PF13499 0.851
DOC_PP2B_LxvP_1 521 524 PF13499 0.854
DOC_PP2B_LxvP_1 70 73 PF13499 0.874
DOC_USP7_MATH_1 174 178 PF00917 0.778
DOC_USP7_MATH_1 187 191 PF00917 0.615
DOC_USP7_MATH_1 215 219 PF00917 0.860
DOC_USP7_MATH_1 253 257 PF00917 0.884
DOC_USP7_MATH_1 307 311 PF00917 0.875
DOC_USP7_MATH_1 456 460 PF00917 0.845
DOC_USP7_MATH_1 53 57 PF00917 0.865
DOC_USP7_MATH_1 555 559 PF00917 0.853
DOC_USP7_MATH_1 569 573 PF00917 0.594
DOC_USP7_MATH_1 624 628 PF00917 0.839
DOC_USP7_MATH_1 649 653 PF00917 0.770
DOC_USP7_MATH_1 73 77 PF00917 0.535
DOC_USP7_MATH_1 93 97 PF00917 0.494
DOC_USP7_UBL2_3 723 727 PF12436 0.843
DOC_WW_Pin1_4 14 19 PF00397 0.695
DOC_WW_Pin1_4 202 207 PF00397 0.857
DOC_WW_Pin1_4 231 236 PF00397 0.870
DOC_WW_Pin1_4 239 244 PF00397 0.745
DOC_WW_Pin1_4 246 251 PF00397 0.620
DOC_WW_Pin1_4 292 297 PF00397 0.839
DOC_WW_Pin1_4 302 307 PF00397 0.690
DOC_WW_Pin1_4 380 385 PF00397 0.878
DOC_WW_Pin1_4 415 420 PF00397 0.869
DOC_WW_Pin1_4 509 514 PF00397 0.861
DOC_WW_Pin1_4 516 521 PF00397 0.744
DOC_WW_Pin1_4 542 547 PF00397 0.814
DOC_WW_Pin1_4 565 570 PF00397 0.856
DOC_WW_Pin1_4 653 658 PF00397 0.780
DOC_WW_Pin1_4 751 756 PF00397 0.842
DOC_WW_Pin1_4 76 81 PF00397 0.873
DOC_WW_Pin1_4 8 13 PF00397 0.852
DOC_WW_Pin1_4 95 100 PF00397 0.485
LIG_14-3-3_CanoR_1 157 163 PF00244 0.766
LIG_14-3-3_CanoR_1 262 268 PF00244 0.875
LIG_14-3-3_CanoR_1 286 290 PF00244 0.851
LIG_14-3-3_CanoR_1 318 327 PF00244 0.882
LIG_14-3-3_CanoR_1 32 37 PF00244 0.713
LIG_14-3-3_CanoR_1 374 378 PF00244 0.880
LIG_14-3-3_CanoR_1 503 513 PF00244 0.856
LIG_14-3-3_CanoR_1 565 569 PF00244 0.855
LIG_14-3-3_CanoR_1 670 676 PF00244 0.824
LIG_14-3-3_CanoR_1 74 80 PF00244 0.881
LIG_14-3-3_CterR_2 765 770 PF00244 0.851
LIG_Actin_WH2_2 29 46 PF00022 0.734
LIG_BRCT_BRCA1_1 398 402 PF00533 0.822
LIG_BRCT_BRCA1_1 514 518 PF00533 0.865
LIG_BRCT_BRCA1_1 571 575 PF00533 0.843
LIG_BRCT_BRCA1_1 621 625 PF00533 0.839
LIG_BRCT_BRCA1_1 651 655 PF00533 0.774
LIG_CSL_BTD_1 700 703 PF09270 0.794
LIG_deltaCOP1_diTrp_1 488 497 PF00928 0.828
LIG_EVH1_1 699 703 PF00568 0.798
LIG_FHA_1 187 193 PF00498 0.844
LIG_FHA_1 410 416 PF00498 0.853
LIG_FHA_1 497 503 PF00498 0.840
LIG_FHA_1 505 511 PF00498 0.718
LIG_FHA_1 545 551 PF00498 0.812
LIG_FHA_1 752 758 PF00498 0.849
LIG_FHA_2 149 155 PF00498 0.794
LIG_FHA_2 404 410 PF00498 0.825
LIG_FHA_2 427 433 PF00498 0.862
LIG_LIR_Apic_2 221 227 PF02991 0.858
LIG_LIR_Apic_2 698 702 PF02991 0.801
LIG_LIR_Gen_1 549 555 PF02991 0.838
LIG_LIR_Gen_1 705 712 PF02991 0.834
LIG_LIR_Nem_3 515 521 PF02991 0.865
LIG_LIR_Nem_3 549 554 PF02991 0.836
LIG_LIR_Nem_3 698 704 PF02991 0.799
LIG_LIR_Nem_3 705 709 PF02991 0.706
LIG_MYND_1 180 184 PF01753 0.821
LIG_Pex14_2 732 736 PF04695 0.807
LIG_SH2_CRK 706 710 PF00017 0.832
LIG_SH2_NCK_1 706 710 PF00017 0.832
LIG_SH2_SRC 529 532 PF00017 0.811
LIG_SH2_STAT5 653 656 PF00017 0.775
LIG_SH2_STAT5 694 697 PF00017 0.799
LIG_SH2_STAT5 706 709 PF00017 0.622
LIG_SH3_1 511 517 PF00018 0.861
LIG_SH3_1 528 534 PF00018 0.516
LIG_SH3_2 243 248 PF14604 0.876
LIG_SH3_3 106 112 PF00018 0.628
LIG_SH3_3 181 187 PF00018 0.828
LIG_SH3_3 203 209 PF00018 0.856
LIG_SH3_3 224 230 PF00018 0.862
LIG_SH3_3 240 246 PF00018 0.594
LIG_SH3_3 247 253 PF00018 0.759
LIG_SH3_3 258 264 PF00018 0.552
LIG_SH3_3 353 359 PF00018 0.877
LIG_SH3_3 507 513 PF00018 0.858
LIG_SH3_3 514 520 PF00018 0.742
LIG_SH3_3 528 534 PF00018 0.569
LIG_SH3_3 643 649 PF00018 0.757
LIG_SH3_3 697 703 PF00018 0.796
LIG_SH3_3 77 83 PF00018 0.870
LIG_SH3_3 97 103 PF00018 0.461
LIG_SH3_5 702 706 PF00018 0.802
LIG_Sin3_3 86 93 PF02671 0.867
LIG_SUMO_SIM_anti_2 297 303 PF11976 0.866
LIG_SUMO_SIM_par_1 102 107 PF11976 0.814
LIG_TRAF2_1 326 329 PF00917 0.876
LIG_TRFH_1 108 112 PF08558 0.777
LIG_TYR_ITIM 704 709 PF00017 0.823
LIG_WRC_WIRS_1 733 738 PF05994 0.806
MOD_CDK_SPK_2 246 251 PF00069 0.882
MOD_CDK_SPxK_1 542 548 PF00069 0.814
MOD_CDK_SPxxK_3 241 248 PF00069 0.878
MOD_CDK_SPxxK_3 380 387 PF00069 0.880
MOD_CDK_SPxxK_3 653 660 PF00069 0.780
MOD_CK1_1 204 210 PF00069 0.856
MOD_CK1_1 218 224 PF00069 0.623
MOD_CK1_1 244 250 PF00069 0.873
MOD_CK1_1 280 286 PF00069 0.856
MOD_CK1_1 288 294 PF00069 0.706
MOD_CK1_1 361 367 PF00069 0.883
MOD_CK1_1 382 388 PF00069 0.875
MOD_CK1_1 457 463 PF00069 0.837
MOD_CK1_1 469 475 PF00069 0.589
MOD_CK1_1 483 489 PF00069 0.568
MOD_CK1_1 492 498 PF00069 0.671
MOD_CK1_1 501 507 PF00069 0.531
MOD_CK1_1 512 518 PF00069 0.511
MOD_CK1_1 556 562 PF00069 0.856
MOD_CK1_1 564 570 PF00069 0.716
MOD_CK1_1 578 584 PF00069 0.589
MOD_CK1_1 626 632 PF00069 0.827
MOD_CK1_1 634 640 PF00069 0.620
MOD_CK1_1 728 734 PF00069 0.813
MOD_CK1_1 76 82 PF00069 0.876
MOD_CK2_1 14 20 PF00069 0.797
MOD_CK2_1 403 409 PF00069 0.822
MOD_DYRK1A_RPxSP_1 565 569 PF00069 0.855
MOD_GlcNHglycan 148 151 PF01048 0.799
MOD_GlcNHglycan 172 175 PF01048 0.763
MOD_GlcNHglycan 176 179 PF01048 0.720
MOD_GlcNHglycan 282 285 PF01048 0.855
MOD_GlcNHglycan 290 293 PF01048 0.703
MOD_GlcNHglycan 307 310 PF01048 0.574
MOD_GlcNHglycan 321 324 PF01048 0.644
MOD_GlcNHglycan 40 43 PF01048 0.752
MOD_GlcNHglycan 456 459 PF01048 0.847
MOD_GlcNHglycan 482 485 PF01048 0.812
MOD_GlcNHglycan 6 9 PF01048 0.866
MOD_GlcNHglycan 621 624 PF01048 0.836
MOD_GlcNHglycan 626 629 PF01048 0.749
MOD_GSK3_1 144 151 PF00069 0.807
MOD_GSK3_1 170 177 PF00069 0.771
MOD_GSK3_1 215 222 PF00069 0.863
MOD_GSK3_1 231 238 PF00069 0.588
MOD_GSK3_1 249 256 PF00069 0.566
MOD_GSK3_1 288 295 PF00069 0.845
MOD_GSK3_1 305 312 PF00069 0.572
MOD_GSK3_1 361 368 PF00069 0.882
MOD_GSK3_1 379 386 PF00069 0.565
MOD_GSK3_1 4 11 PF00069 0.861
MOD_GSK3_1 471 478 PF00069 0.797
MOD_GSK3_1 482 489 PF00069 0.619
MOD_GSK3_1 492 499 PF00069 0.654
MOD_GSK3_1 512 519 PF00069 0.511
MOD_GSK3_1 555 562 PF00069 0.855
MOD_GSK3_1 564 571 PF00069 0.697
MOD_GSK3_1 576 583 PF00069 0.626
MOD_GSK3_1 619 626 PF00069 0.838
MOD_GSK3_1 627 634 PF00069 0.675
MOD_GSK3_1 649 656 PF00069 0.771
MOD_GSK3_1 68 75 PF00069 0.876
MOD_GSK3_1 728 735 PF00069 0.813
MOD_LATS_1 275 281 PF00433 0.855
MOD_N-GLC_1 253 258 PF02516 0.881
MOD_N-GLC_1 280 285 PF02516 0.856
MOD_N-GLC_1 476 481 PF02516 0.803
MOD_N-GLC_1 492 497 PF02516 0.549
MOD_NEK2_1 188 193 PF00069 0.847
MOD_NEK2_1 373 378 PF00069 0.879
MOD_NEK2_1 395 400 PF00069 0.833
MOD_NEK2_1 403 408 PF00069 0.680
MOD_NEK2_1 502 507 PF00069 0.850
MOD_NEK2_1 575 580 PF00069 0.841
MOD_NEK2_1 619 624 PF00069 0.835
MOD_NEK2_1 680 685 PF00069 0.824
MOD_NEK2_1 695 700 PF00069 0.539
MOD_NEK2_1 732 737 PF00069 0.808
MOD_OFUCOSY 467 473 PF10250 0.803
MOD_PIKK_1 158 164 PF00454 0.766
MOD_PIKK_1 309 315 PF00454 0.884
MOD_PIKK_1 556 562 PF00454 0.856
MOD_PIKK_1 628 634 PF00454 0.811
MOD_PKA_1 716 722 PF00069 0.852
MOD_PKA_2 268 274 PF00069 0.875
MOD_PKA_2 285 291 PF00069 0.552
MOD_PKA_2 373 379 PF00069 0.881
MOD_PKA_2 502 508 PF00069 0.852
MOD_PKA_2 564 570 PF00069 0.856
MOD_PKA_2 716 722 PF00069 0.852
MOD_PKA_2 73 79 PF00069 0.883
MOD_Plk_1 19 25 PF00069 0.770
MOD_Plk_1 253 259 PF00069 0.878
MOD_Plk_1 492 498 PF00069 0.829
MOD_Plk_1 680 686 PF00069 0.821
MOD_Plk_1 704 710 PF00069 0.825
MOD_Plk_4 457 463 PF00069 0.837
MOD_Plk_4 631 637 PF00069 0.791
MOD_Plk_4 649 655 PF00069 0.456
MOD_Plk_4 704 710 PF00069 0.825
MOD_ProDKin_1 202 208 PF00069 0.858
MOD_ProDKin_1 231 237 PF00069 0.867
MOD_ProDKin_1 239 245 PF00069 0.737
MOD_ProDKin_1 246 252 PF00069 0.621
MOD_ProDKin_1 292 298 PF00069 0.842
MOD_ProDKin_1 302 308 PF00069 0.693
MOD_ProDKin_1 380 386 PF00069 0.878
MOD_ProDKin_1 415 421 PF00069 0.867
MOD_ProDKin_1 509 515 PF00069 0.860
MOD_ProDKin_1 516 522 PF00069 0.743
MOD_ProDKin_1 542 548 PF00069 0.814
MOD_ProDKin_1 565 571 PF00069 0.854
MOD_ProDKin_1 653 659 PF00069 0.779
MOD_ProDKin_1 751 757 PF00069 0.845
MOD_ProDKin_1 76 82 PF00069 0.876
MOD_ProDKin_1 8 14 PF00069 0.849
MOD_ProDKin_1 95 101 PF00069 0.485
MOD_SUMO_rev_2 114 122 PF00179 0.744
TRG_DiLeu_BaLyEn_6 100 105 PF01217 0.813
TRG_DiLeu_BaLyEn_6 177 182 PF01217 0.807
TRG_DiLeu_BaLyEn_6 531 536 PF01217 0.817
TRG_ENDOCYTIC_2 706 709 PF00928 0.832
TRG_ER_diArg_1 344 346 PF00400 0.890
TRG_ER_diArg_1 442 445 PF00400 0.868
TRG_ER_diArg_1 715 718 PF00400 0.851
TRG_ER_diArg_1 759 762 PF00400 0.855
TRG_ER_diArg_1 765 768 PF00400 0.748
TRG_NES_CRM1_1 663 675 PF08389 0.812
TRG_NLS_MonoCore_2 714 719 PF00514 0.845
TRG_NLS_MonoExtC_3 714 720 PF00514 0.847
TRG_Pf-PMV_PEXEL_1 405 409 PF00026 0.824

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS