Lactamase_B domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

Beta-lactamase superfamily domain containing protein, putative

Species:

Leishmania braziliensis

UniProt:

A4HCF6_LEIBR

TriTrypDb:

LbrM.22.1030 , LBRM2903_220016000

Length:

215

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HCF6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HCF6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	137	139	PF00675	0.600
CLV_NRD_NRD_1	190	192	PF00675	0.649
CLV_PCSK_KEX2_1	137	139	PF00082	0.600
CLV_PCSK_KEX2_1	192	194	PF00082	0.623
CLV_PCSK_PC1ET2_1	192	194	PF00082	0.623
CLV_PCSK_SKI1_1	192	196	PF00082	0.606
DEG_APCC_DBOX_1	168	176	PF00400	0.672
DEG_Nend_UBRbox_2	1	3	PF02207	0.776
DOC_MAPK_gen_1	9	18	PF00069	0.688
DOC_MAPK_MEF2A_6	102	110	PF00069	0.576
DOC_MAPK_MEF2A_6	152	161	PF00069	0.625
DOC_MAPK_MEF2A_6	9	18	PF00069	0.688
DOC_USP7_MATH_1	117	121	PF00917	0.639
DOC_USP7_MATH_1	177	181	PF00917	0.764
DOC_USP7_MATH_1	27	31	PF00917	0.808
DOC_USP7_MATH_1	61	65	PF00917	0.661
DOC_USP7_MATH_1	75	79	PF00917	0.436
DOC_USP7_MATH_1	90	94	PF00917	0.345
DOC_WW_Pin1_4	22	27	PF00397	0.801
LIG_14-3-3_CanoR_1	137	141	PF00244	0.592
LIG_14-3-3_CanoR_1	198	203	PF00244	0.606
LIG_BRCT_BRCA1_1	92	96	PF00533	0.603
LIG_Clathr_ClatBox_1	100	104	PF01394	0.576
LIG_Clathr_ClatBox_1	156	160	PF01394	0.632
LIG_FHA_1	137	143	PF00498	0.600
LIG_FHA_1	151	157	PF00498	0.380
LIG_FHA_2	183	189	PF00498	0.698
LIG_LIR_Nem_3	35	41	PF02991	0.616
LIG_Pex14_2	141	145	PF04695	0.631
LIG_RPA_C_Fungi	193	205	PF08784	0.611
LIG_SH2_CRK	39	43	PF00017	0.578
LIG_SH2_STAT3	206	209	PF00017	0.710
LIG_SH2_STAT5	122	125	PF00017	0.598
LIG_SH2_STAT5	140	143	PF00017	0.285
LIG_SH2_STAT5	15	18	PF00017	0.741
LIG_SH2_STAT5	49	52	PF00017	0.611
LIG_SH2_STAT5	82	85	PF00017	0.610
LIG_SH3_3	14	20	PF00018	0.740
LIG_SUMO_SIM_anti_2	104	109	PF11976	0.575
LIG_SUMO_SIM_par_1	104	109	PF11976	0.575
LIG_SUMO_SIM_par_1	155	160	PF11976	0.636
MOD_CK1_1	30	36	PF00069	0.742
MOD_CK1_1	64	70	PF00069	0.774
MOD_CK1_1	84	90	PF00069	0.245
MOD_CK2_1	182	188	PF00069	0.713
MOD_GlcNHglycan	117	120	PF01048	0.651
MOD_GlcNHglycan	179	182	PF01048	0.750
MOD_GSK3_1	27	34	PF00069	0.788
MOD_GSK3_1	57	64	PF00069	0.628
MOD_PIKK_1	61	67	PF00454	0.692
MOD_PKA_2	136	142	PF00069	0.588
MOD_PKA_2	57	63	PF00069	0.619
MOD_ProDKin_1	22	28	PF00069	0.803
MOD_SUMO_rev_2	188	194	PF00179	0.645
MOD_SUMO_rev_2	2	11	PF00179	0.688
TRG_ENDOCYTIC_2	15	18	PF00928	0.741
TRG_ENDOCYTIC_2	49	52	PF00928	0.611
TRG_ER_diArg_1	136	138	PF00400	0.601
TRG_NES_CRM1_1	98	109	PF08389	0.581