DUF1073 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HCD1_LEIBR

TriTrypDb:

LbrM.22.0700 , LBRM2903_220012400

Length:

212

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

A4HCD1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HCD1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	160	164	PF00656	0.790
CLV_PCSK_KEX2_1	40	42	PF00082	0.587
CLV_PCSK_PC1ET2_1	40	42	PF00082	0.587
CLV_PCSK_SKI1_1	48	52	PF00082	0.549
DEG_Nend_Nbox_1	1	3	PF02207	0.598
DOC_CYCLIN_yCln2_LP_2	2	8	PF00134	0.579
DOC_PP4_FxxP_1	103	106	PF00568	0.751
DOC_PP4_FxxP_1	78	81	PF00568	0.639
DOC_USP7_UBL2_3	33	37	PF12436	0.807
DOC_WW_Pin1_4	40	45	PF00397	0.785
DOC_WW_Pin1_4	52	57	PF00397	0.339
DOC_WW_Pin1_4	69	74	PF00397	0.405
LIG_14-3-3_CanoR_1	83	90	PF00244	0.612
LIG_BRCT_BRCA1_1	74	78	PF00533	0.635
LIG_CSL_BTD_1	2	5	PF09270	0.585
LIG_deltaCOP1_diTrp_1	199	205	PF00928	0.776
LIG_EVH1_2	80	84	PF00568	0.631
LIG_FHA_1	153	159	PF00498	0.767
LIG_FHA_1	41	47	PF00498	0.784
LIG_FHA_1	63	69	PF00498	0.603
LIG_FHA_1	87	93	PF00498	0.549
LIG_FHA_2	140	146	PF00498	0.786
LIG_LIR_Apic_2	100	106	PF02991	0.549
LIG_LIR_Apic_2	75	81	PF02991	0.637
LIG_LIR_Gen_1	203	211	PF02991	0.790
LIG_LIR_Nem_3	203	208	PF02991	0.786
LIG_LIR_Nem_3	60	66	PF02991	0.756
LIG_PCNA_yPIPBox_3	129	141	PF02747	0.794
LIG_Pex14_1	201	205	PF04695	0.780
LIG_Pex14_2	45	49	PF04695	0.650
LIG_Pex14_2	50	54	PF04695	0.462
LIG_SH2_CRK	63	67	PF00017	0.604
LIG_SH2_STAT3	111	114	PF00017	0.813
LIG_SH2_STAT3	189	192	PF00017	0.794
LIG_SH2_STAT5	111	114	PF00017	0.813
LIG_SH2_STAT5	141	144	PF00017	0.786
LIG_SH3_3	2	8	PF00018	0.579
LIG_SH3_3	74	80	PF00018	0.635
LIG_SH3_4	105	112	PF00018	0.802
LIG_SUMO_SIM_anti_2	57	63	PF11976	0.549
LIG_SUMO_SIM_par_1	64	69	PF11976	0.602
LIG_TRAF2_1	143	146	PF00917	0.784
LIG_TRAF2_1	185	188	PF00917	0.810
LIG_TRFH_1	4	8	PF08558	0.449
LIG_TYR_ITIM	61	66	PF00017	0.759
MOD_CDK_SPxxK_3	69	76	PF00069	0.622
MOD_CK1_1	162	168	PF00069	0.814
MOD_CK1_1	55	61	PF00069	0.549
MOD_CK1_1	69	75	PF00069	0.443
MOD_CK2_1	139	145	PF00069	0.790
MOD_GlcNHglycan	163	167	PF01048	0.615
MOD_GSK3_1	119	126	PF00069	0.809
MOD_GSK3_1	165	172	PF00069	0.819
MOD_GSK3_1	62	69	PF00069	0.761
MOD_GSK3_1	82	89	PF00069	0.364
MOD_GSK3_1	97	104	PF00069	0.287
MOD_NEK2_1	176	181	PF00069	0.801
MOD_NEK2_1	62	67	PF00069	0.761
MOD_NEK2_1	94	99	PF00069	0.549
MOD_PIKK_1	206	212	PF00454	0.799
MOD_PIKK_1	82	88	PF00454	0.616
MOD_PKA_2	152	158	PF00069	0.756
MOD_PKA_2	82	88	PF00069	0.616
MOD_Plk_4	57	63	PF00069	0.549
MOD_Plk_4	94	100	PF00069	0.549
MOD_ProDKin_1	40	46	PF00069	0.785
MOD_ProDKin_1	52	58	PF00069	0.339
MOD_ProDKin_1	69	75	PF00069	0.406
TRG_DiLeu_BaLyEn_6	171	176	PF01217	0.814
TRG_DiLeu_BaLyEn_6	2	7	PF01217	0.581
TRG_ENDOCYTIC_2	63	66	PF00928	0.604
TRG_ER_FFAT_2	135	146	PF00635	0.789
TRG_Pf-PMV_PEXEL_1	174	178	PF00026	0.612