Formin-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Formin-like protein

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HCC8_LEIBR

TriTrypDb:

LbrM.22.0970 , LBRM2903_220015400

Length:

814

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HCC8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HCC8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	147	149	PF00675	0.832
CLV_NRD_NRD_1	186	188	PF00675	0.787
CLV_NRD_NRD_1	213	215	PF00675	0.889
CLV_NRD_NRD_1	223	225	PF00675	0.702
CLV_NRD_NRD_1	605	607	PF00675	0.856
CLV_NRD_NRD_1	701	703	PF00675	0.711
CLV_NRD_NRD_1	719	721	PF00675	0.482
CLV_NRD_NRD_1	95	97	PF00675	0.873
CLV_PCSK_KEX2_1	147	149	PF00082	0.832
CLV_PCSK_KEX2_1	186	188	PF00082	0.787
CLV_PCSK_KEX2_1	215	217	PF00082	0.888
CLV_PCSK_KEX2_1	223	225	PF00082	0.737
CLV_PCSK_KEX2_1	605	607	PF00082	0.856
CLV_PCSK_KEX2_1	701	703	PF00082	0.711
CLV_PCSK_KEX2_1	719	721	PF00082	0.482
CLV_PCSK_PC1ET2_1	215	217	PF00082	0.888
CLV_PCSK_SKI1_1	148	152	PF00082	0.831
CLV_PCSK_SKI1_1	2	6	PF00082	0.865
CLV_PCSK_SKI1_1	489	493	PF00082	0.712
CLV_PCSK_SKI1_1	535	539	PF00082	0.697
CLV_PCSK_SKI1_1	662	666	PF00082	0.759
CLV_PCSK_SKI1_1	83	87	PF00082	0.854
CLV_PCSK_SKI1_1	96	100	PF00082	0.658
CLV_Separin_Metazoa	659	663	PF03568	0.766
DEG_APCC_DBOX_1	445	453	PF00400	0.847
DEG_APCC_DBOX_1	534	542	PF00400	0.695
DEG_Nend_UBRbox_1	1	4	PF02207	0.869
DEG_SCF_FBW7_2	286	292	PF00400	0.878
DEG_SPOP_SBC_1	218	222	PF00917	0.882
DEG_SPOP_SBC_1	569	573	PF00917	0.868
DEG_SPOP_SBC_1	90	94	PF00917	0.852
DOC_CKS1_1	102	107	PF01111	0.852
DOC_CKS1_1	283	288	PF01111	0.855
DOC_CKS1_1	334	339	PF01111	0.842
DOC_CKS1_1	461	466	PF01111	0.848
DOC_CKS1_1	618	623	PF01111	0.839
DOC_CYCLIN_RxL_1	775	783	PF00134	0.685
DOC_CYCLIN_yCln2_LP_2	618	624	PF00134	0.840
DOC_CYCLIN_yCln2_LP_2	725	731	PF00134	0.836
DOC_MAPK_DCC_7	249	259	PF00069	0.860
DOC_MAPK_gen_1	532	541	PF00069	0.700
DOC_MAPK_gen_1	719	725	PF00069	0.814
DOC_PP1_RVXF_1	700	707	PF00149	0.705
DOC_PP2B_LxvP_1	257	260	PF13499	0.855
DOC_PP2B_LxvP_1	352	355	PF13499	0.838
DOC_PP2B_LxvP_1	370	373	PF13499	0.526
DOC_PP2B_LxvP_1	388	391	PF13499	0.525
DOC_PP2B_LxvP_1	433	436	PF13499	0.855
DOC_PP2B_LxvP_1	631	634	PF13499	0.863
DOC_PP2B_LxvP_1	725	728	PF13499	0.838
DOC_USP7_MATH_1	194	198	PF00917	0.833
DOC_USP7_MATH_1	218	222	PF00917	0.882
DOC_USP7_MATH_1	232	236	PF00917	0.622
DOC_USP7_MATH_1	240	244	PF00917	0.730
DOC_USP7_MATH_1	28	32	PF00917	0.808
DOC_USP7_MATH_1	339	343	PF00917	0.859
DOC_USP7_MATH_1	348	352	PF00917	0.688
DOC_USP7_MATH_1	357	361	PF00917	0.534
DOC_USP7_MATH_1	366	370	PF00917	0.531
DOC_USP7_MATH_1	375	379	PF00917	0.530
DOC_USP7_MATH_1	384	388	PF00917	0.531
DOC_USP7_MATH_1	39	43	PF00917	0.521
DOC_USP7_MATH_1	393	397	PF00917	0.532
DOC_USP7_MATH_1	402	406	PF00917	0.533
DOC_USP7_MATH_1	411	415	PF00917	0.532
DOC_USP7_MATH_1	420	424	PF00917	0.540
DOC_USP7_MATH_1	429	433	PF00917	0.551
DOC_USP7_MATH_1	456	460	PF00917	0.847
DOC_USP7_MATH_1	471	475	PF00917	0.601
DOC_USP7_MATH_1	480	484	PF00917	0.632
DOC_USP7_MATH_1	54	58	PF00917	0.573
DOC_USP7_MATH_1	540	544	PF00917	0.686
DOC_USP7_MATH_1	569	573	PF00917	0.868
DOC_USP7_MATH_1	587	591	PF00917	0.569
DOC_USP7_MATH_1	59	63	PF00917	0.512
DOC_USP7_MATH_1	610	614	PF00917	0.797
DOC_USP7_MATH_1	622	626	PF00917	0.647
DOC_USP7_MATH_1	671	675	PF00917	0.838
DOC_USP7_MATH_1	71	75	PF00917	0.565
DOC_USP7_MATH_1	733	737	PF00917	0.857
DOC_USP7_MATH_1	90	94	PF00917	0.519
DOC_WW_Pin1_4	101	106	PF00397	0.538
DOC_WW_Pin1_4	113	118	PF00397	0.586
DOC_WW_Pin1_4	167	172	PF00397	0.852
DOC_WW_Pin1_4	173	178	PF00397	0.726
DOC_WW_Pin1_4	233	238	PF00397	0.871
DOC_WW_Pin1_4	261	266	PF00397	0.857
DOC_WW_Pin1_4	282	287	PF00397	0.848
DOC_WW_Pin1_4	329	334	PF00397	0.851
DOC_WW_Pin1_4	444	449	PF00397	0.849
DOC_WW_Pin1_4	460	465	PF00397	0.566
DOC_WW_Pin1_4	565	570	PF00397	0.850
DOC_WW_Pin1_4	576	581	PF00397	0.675
DOC_WW_Pin1_4	617	622	PF00397	0.831
DOC_WW_Pin1_4	672	677	PF00397	0.851
DOC_WW_Pin1_4	72	77	PF00397	0.859
DOC_WW_Pin1_4	738	743	PF00397	0.830
DOC_WW_Pin1_4	753	758	PF00397	0.531
DOC_WW_Pin1_4	83	88	PF00397	0.657
DOC_WW_Pin1_4	9	14	PF00397	0.863
DOC_WW_Pin1_4	91	96	PF00397	0.531
LIG_14-3-3_CanoR_1	147	157	PF00244	0.835
LIG_14-3-3_CanoR_1	653	661	PF00244	0.797
LIG_14-3-3_CanoR_1	677	682	PF00244	0.882
LIG_14-3-3_CanoR_1	719	724	PF00244	0.808
LIG_14-3-3_CanoR_1	795	803	PF00244	0.677
LIG_14-3-3_CanoR_1	96	105	PF00244	0.871
LIG_CaM_IQ_9	654	670	PF13499	0.782
LIG_CSL_BTD_1	114	117	PF09270	0.791
LIG_EVH1_1	352	356	PF00568	0.839
LIG_EVH1_1	370	374	PF00568	0.524
LIG_EVH1_1	388	392	PF00568	0.523
LIG_EVH1_1	433	437	PF00568	0.855
LIG_EVH1_1	631	635	PF00568	0.859
LIG_FHA_1	10	16	PF00498	0.858
LIG_FHA_1	102	108	PF00498	0.848
LIG_FHA_1	149	155	PF00498	0.832
LIG_FHA_1	245	251	PF00498	0.870
LIG_FHA_1	261	267	PF00498	0.578
LIG_FHA_1	325	331	PF00498	0.868
LIG_FHA_1	461	467	PF00498	0.852
LIG_FHA_1	655	661	PF00498	0.785
LIG_FHA_2	618	624	PF00498	0.840
LIG_LIR_Apic_2	745	750	PF02991	0.840
LIG_LIR_Gen_1	511	522	PF02991	0.691
LIG_LIR_Gen_1	612	622	PF02991	0.819
LIG_LIR_LC3C_4	447	452	PF02991	0.843
LIG_LIR_Nem_3	511	517	PF02991	0.689
LIG_LIR_Nem_3	612	618	PF02991	0.810
LIG_PCNA_yPIPBox_3	653	665	PF02747	0.785
LIG_SH2_CRK	283	287	PF00017	0.851
LIG_SH2_CRK	514	518	PF00017	0.694
LIG_SH2_CRK	615	619	PF00017	0.819
LIG_SH2_CRK	747	751	PF00017	0.842
LIG_SH2_SRC	708	711	PF00017	0.718
LIG_SH2_STAP1	326	330	PF00017	0.867
LIG_SH2_STAT3	499	502	PF00017	0.700
LIG_SH2_STAT3	806	809	PF00017	0.686
LIG_SH2_STAT5	326	329	PF00017	0.866
LIG_SH2_STAT5	499	502	PF00017	0.700
LIG_SH2_STAT5	551	554	PF00017	0.767
LIG_SH2_STAT5	703	706	PF00017	0.697
LIG_SH2_STAT5	806	809	PF00017	0.686
LIG_SH3_1	283	289	PF00018	0.857
LIG_SH3_3	102	108	PF00018	0.532
LIG_SH3_3	228	234	PF00018	0.873
LIG_SH3_3	236	242	PF00018	0.725
LIG_SH3_3	263	269	PF00018	0.853
LIG_SH3_3	283	289	PF00018	0.507
LIG_SH3_3	327	333	PF00018	0.859
LIG_SH3_3	340	346	PF00018	0.620
LIG_SH3_3	350	356	PF00018	0.666
LIG_SH3_3	358	364	PF00018	0.532
LIG_SH3_3	368	374	PF00018	0.526
LIG_SH3_3	376	382	PF00018	0.528
LIG_SH3_3	386	392	PF00018	0.526
LIG_SH3_3	394	400	PF00018	0.528
LIG_SH3_3	403	409	PF00018	0.546
LIG_SH3_3	412	418	PF00018	0.529
LIG_SH3_3	421	427	PF00018	0.539
LIG_SH3_3	431	437	PF00018	0.526
LIG_SH3_3	442	448	PF00018	0.653
LIG_SH3_3	449	455	PF00018	0.521
LIG_SH3_3	458	464	PF00018	0.570
LIG_SH3_3	626	632	PF00018	0.867
LIG_SH3_3	725	731	PF00018	0.836
LIG_SH3_3	737	743	PF00018	0.623
LIG_SH3_3	84	90	PF00018	0.840
LIG_SUMO_SIM_anti_2	447	453	PF11976	0.843
LIG_SUMO_SIM_par_1	36	42	PF11976	0.723
LIG_SUMO_SIM_par_1	536	543	PF11976	0.692
LIG_SxIP_EBH_1	249	260	PF03271	0.858
LIG_TRAF2_1	197	200	PF00917	0.859
LIG_TRAF2_1	522	525	PF00917	0.698
LIG_TRAF2_1	656	659	PF00917	0.790
LIG_TYR_ITIM	512	517	PF00017	0.697
MOD_CDC14_SPxK_1	268	271	PF00782	0.840
MOD_CDC14_SPxK_1	94	97	PF00782	0.872
MOD_CDK_SPK_2	672	677	PF00069	0.851
MOD_CDK_SPK_2	91	96	PF00069	0.863
MOD_CDK_SPxK_1	265	271	PF00069	0.848
MOD_CDK_SPxK_1	91	97	PF00069	0.867
MOD_CDK_SPxxK_3	72	79	PF00069	0.861
MOD_CK1_1	113	119	PF00069	0.792
MOD_CK1_1	219	225	PF00069	0.881
MOD_CK1_1	243	249	PF00069	0.878
MOD_CK1_1	332	338	PF00069	0.839
MOD_CK1_1	474	480	PF00069	0.847
MOD_CK1_1	555	561	PF00069	0.796
MOD_CK1_1	570	576	PF00069	0.608
MOD_CK1_1	588	594	PF00069	0.571
MOD_CK1_1	617	623	PF00069	0.836
MOD_CK1_1	62	68	PF00069	0.880
MOD_CK1_1	69	75	PF00069	0.743
MOD_CK2_1	162	168	PF00069	0.851
MOD_CK2_1	194	200	PF00069	0.841
MOD_CK2_1	571	577	PF00069	0.871
MOD_GlcNHglycan	112	115	PF01048	0.825
MOD_GlcNHglycan	228	231	PF01048	0.884
MOD_GlcNHglycan	251	254	PF01048	0.857
MOD_GlcNHglycan	292	295	PF01048	0.891
MOD_GlcNHglycan	456	459	PF01048	0.846
MOD_GlcNHglycan	473	476	PF01048	0.565
MOD_GlcNHglycan	542	545	PF01048	0.686
MOD_GlcNHglycan	639	642	PF01048	0.881
MOD_GlcNHglycan	654	657	PF01048	0.542
MOD_GlcNHglycan	66	69	PF01048	0.880
MOD_GlcNHglycan	71	74	PF01048	0.774
MOD_GSK3_1	204	211	PF00069	0.882
MOD_GSK3_1	240	247	PF00069	0.873
MOD_GSK3_1	261	268	PF00069	0.857
MOD_GSK3_1	329	336	PF00069	0.852
MOD_GSK3_1	456	463	PF00069	0.850
MOD_GSK3_1	470	477	PF00069	0.616
MOD_GSK3_1	5	12	PF00069	0.870
MOD_GSK3_1	545	552	PF00069	0.721
MOD_GSK3_1	563	570	PF00069	0.528
MOD_GSK3_1	571	578	PF00069	0.732
MOD_GSK3_1	610	617	PF00069	0.805
MOD_GSK3_1	62	69	PF00069	0.880
MOD_GSK3_1	672	679	PF00069	0.858
MOD_GSK3_1	734	741	PF00069	0.852
MOD_GSK3_1	96	103	PF00069	0.878
MOD_LATS_1	206	212	PF00433	0.884
MOD_LATS_1	717	723	PF00433	0.798
MOD_N-GLC_1	204	209	PF02516	0.881
MOD_N-GLC_1	226	231	PF02516	0.881
MOD_N-GLC_1	261	266	PF02516	0.857
MOD_N-GLC_1	481	486	PF02516	0.769
MOD_N-GLC_1	563	568	PF02516	0.838
MOD_NEK2_1	290	295	PF00069	0.893
MOD_NEK2_1	5	10	PF00069	0.871
MOD_NEK2_1	545	550	PF00069	0.704
MOD_NEK2_1	637	642	PF00069	0.882
MOD_NEK2_1	98	103	PF00069	0.874
MOD_NEK2_2	610	615	PF00069	0.801
MOD_PIKK_1	14	20	PF00454	0.839
MOD_PIKK_1	595	601	PF00454	0.883
MOD_PIKK_1	654	660	PF00454	0.790
MOD_PIKK_1	98	104	PF00454	0.871
MOD_PKA_1	719	725	PF00069	0.814
MOD_PKA_1	96	102	PF00069	0.880
MOD_PKA_2	146	152	PF00069	0.830
MOD_PKA_2	526	532	PF00069	0.705
MOD_PKA_2	552	558	PF00069	0.776
MOD_PKA_2	575	581	PF00069	0.868
MOD_PKA_2	652	658	PF00069	0.818
MOD_PKA_2	676	682	PF00069	0.879
MOD_PKA_2	719	725	PF00069	0.814
MOD_PKB_1	214	222	PF00069	0.885
MOD_PKB_1	224	232	PF00069	0.702
MOD_Plk_1	226	232	PF00069	0.877
MOD_Plk_1	481	487	PF00069	0.765
MOD_Plk_1	588	594	PF00069	0.887
MOD_Plk_1	622	628	PF00069	0.858
MOD_Plk_4	610	616	PF00069	0.803
MOD_Plk_4	759	765	PF00069	0.744
MOD_ProDKin_1	101	107	PF00069	0.538
MOD_ProDKin_1	113	119	PF00069	0.582
MOD_ProDKin_1	167	173	PF00069	0.852
MOD_ProDKin_1	233	239	PF00069	0.867
MOD_ProDKin_1	261	267	PF00069	0.858
MOD_ProDKin_1	282	288	PF00069	0.852
MOD_ProDKin_1	329	335	PF00069	0.851
MOD_ProDKin_1	444	450	PF00069	0.849
MOD_ProDKin_1	460	466	PF00069	0.568
MOD_ProDKin_1	565	571	PF00069	0.854
MOD_ProDKin_1	576	582	PF00069	0.677
MOD_ProDKin_1	617	623	PF00069	0.836
MOD_ProDKin_1	672	678	PF00069	0.854
MOD_ProDKin_1	72	78	PF00069	0.860
MOD_ProDKin_1	738	744	PF00069	0.831
MOD_ProDKin_1	753	759	PF00069	0.525
MOD_ProDKin_1	83	89	PF00069	0.657
MOD_ProDKin_1	9	15	PF00069	0.863
MOD_ProDKin_1	91	97	PF00069	0.534
TRG_DiLeu_BaEn_1	156	161	PF01217	0.841
TRG_DiLeu_BaEn_1	488	493	PF01217	0.715
TRG_DiLeu_BaLyEn_6	11	16	PF01217	0.855
TRG_DiLeu_BaLyEn_6	252	257	PF01217	0.859
TRG_DiLeu_BaLyEn_6	445	450	PF01217	0.849
TRG_ENDOCYTIC_2	514	517	PF00928	0.694
TRG_ENDOCYTIC_2	615	618	PF00928	0.820
TRG_ENDOCYTIC_2	703	706	PF00928	0.697
TRG_ER_diArg_1	146	148	PF00400	0.827
TRG_ER_diArg_1	223	226	PF00400	0.881
TRG_ER_diArg_1	605	607	PF00400	0.856
TRG_ER_diArg_1	700	702	PF00400	0.716
TRG_ER_diArg_1	718	720	PF00400	0.472
TRG_NES_CRM1_1	153	166	PF08389	0.841
TRG_NES_CRM1_1	781	794	PF08389	0.678
TRG_NLS_MonoExtN_4	212	218	PF00514	0.888
TRG_Pf-PMV_PEXEL_1	778	783	PF00026	0.680