Glucoamylase-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

glucoamylase-like protein

Species:

Leishmania braziliensis

UniProt:

A4HCB0_LEIBR

TriTrypDb:

LbrM.22.0590 , LBRM2903_220011500

Length:

1213

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HCB0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HCB0

Function

Could not find GO biological_process term for this entry.

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Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	1
GO:0003723	RNA binding	4	1
GO:0005488	binding	1	1
GO:0097159	organic cyclic compound binding	2	1
GO:1901363	heterocyclic compound binding	2	1

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1111	1115	PF00656	0.536
CLV_C14_Caspase3-7	1186	1190	PF00656	0.546
CLV_C14_Caspase3-7	229	233	PF00656	0.595
CLV_C14_Caspase3-7	792	796	PF00656	0.703
CLV_C14_Caspase3-7	950	954	PF00656	0.647
CLV_NRD_NRD_1	1009	1011	PF00675	0.834
CLV_NRD_NRD_1	1089	1091	PF00675	0.680
CLV_NRD_NRD_1	227	229	PF00675	0.795
CLV_NRD_NRD_1	484	486	PF00675	0.783
CLV_NRD_NRD_1	891	893	PF00675	0.599

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PDM9	Leptomonas seymouri	32%	100%
A0A3S7WX15	Leishmania donovani	59%	100%
A4HZU3	Leishmania infantum	62%	100%
E9AVP8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	60%	100%
Q4QBT1	Leishmania major	62%	100%

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