Putative 40S ribosomal protein S15

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

40S ribosomal protein S15, putative

Species:

Leishmania braziliensis

UniProt:

A4HC91_LEIBR

TriTrypDb:

LbrM.22.0400 , LBRM2903_220009600

Length:

152

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 25

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 13
NetGPI	no	yes: 0, no: 13

Cellular components
Term	Name	Level	Count
GO:0015935	small ribosomal subunit	4	14
GO:0032991	protein-containing complex	1	14
GO:0044391	ribosomal subunit	3	14
GO:1990904	ribonucleoprotein complex	2	14
GO:0005737	cytoplasm	2	1
GO:0022627	cytosolic small ribosomal subunit	5	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4HC91

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HC91

Function

Biological processes
Term	Name	Level	Count
GO:0006412	translation	4	14
GO:0006518	peptide metabolic process	4	14
GO:0006807	nitrogen compound metabolic process	2	14
GO:0008152	metabolic process	1	14
GO:0009058	biosynthetic process	2	14
GO:0009059	macromolecule biosynthetic process	4	14
GO:0009987	cellular process	1	14
GO:0019538	protein metabolic process	3	14
GO:0034641	cellular nitrogen compound metabolic process	3	14
GO:0034645	obsolete cellular macromolecule biosynthetic process	4	14
GO:0043043	peptide biosynthetic process	5	14
GO:0043170	macromolecule metabolic process	3	14
GO:0043603	amide metabolic process	3	14
GO:0043604	amide biosynthetic process	4	14
GO:0044237	cellular metabolic process	2	14
GO:0044238	primary metabolic process	2	14
GO:0044249	cellular biosynthetic process	3	14
GO:0044260	obsolete cellular macromolecule metabolic process	3	14
GO:0044271	cellular nitrogen compound biosynthetic process	4	14
GO:0071704	organic substance metabolic process	2	14
GO:1901564	organonitrogen compound metabolic process	3	14
GO:1901566	organonitrogen compound biosynthetic process	4	14
GO:1901576	organic substance biosynthetic process	3	14
GO:0000028	ribosomal small subunit assembly	7	1
GO:0016043	cellular component organization	3	1
GO:0022607	cellular component assembly	4	1
GO:0022618	ribonucleoprotein complex assembly	6	1
GO:0043933	protein-containing complex organization	4	1
GO:0065003	protein-containing complex assembly	5	1
GO:0071826	ribonucleoprotein complex subunit organization	5	1
GO:0071840	cellular component organization or biogenesis	2	1

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	14
GO:0003723	RNA binding	4	14
GO:0003735	structural constituent of ribosome	2	14
GO:0005198	structural molecule activity	1	14
GO:0005488	binding	1	14
GO:0097159	organic cyclic compound binding	2	14
GO:1901363	heterocyclic compound binding	2	14

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	49	51	PF00675	0.425
CLV_NRD_NRD_1	58	60	PF00675	0.246
CLV_PCSK_FUR_1	47	51	PF00082	0.412
CLV_PCSK_KEX2_1	49	51	PF00082	0.422
CLV_PCSK_KEX2_1	58	60	PF00082	0.247
CLV_PCSK_KEX2_1	65	67	PF00082	0.247
CLV_PCSK_PC1ET2_1	65	67	PF00082	0.247
CLV_PCSK_PC7_1	54	60	PF00082	0.307
CLV_PCSK_SKI1_1	131	135	PF00082	0.359
CLV_PCSK_SKI1_1	68	72	PF00082	0.255
CLV_PCSK_SKI1_1	81	85	PF00082	0.259
DOC_AGCK_PIF_1	19	24	PF00069	0.437
DOC_CKS1_1	91	96	PF01111	0.447
DOC_MAPK_gen_1	58	64	PF00069	0.498
DOC_MAPK_gen_1	68	76	PF00069	0.476
DOC_USP7_MATH_1	142	146	PF00917	0.482
DOC_USP7_UBL2_3	71	75	PF12436	0.479
DOC_WW_Pin1_4	90	95	PF00397	0.447
LIG_BIR_II_1	1	5	PF00653	0.585
LIG_BRCT_BRCA1_1	144	148	PF00533	0.493
LIG_LIR_Gen_1	18	27	PF02991	0.442
LIG_LIR_Gen_1	8	16	PF02991	0.481
LIG_LIR_Nem_3	127	133	PF02991	0.447
LIG_LIR_Nem_3	145	151	PF02991	0.547
LIG_LIR_Nem_3	16	22	PF02991	0.495
LIG_LIR_Nem_3	23	27	PF02991	0.409
LIG_LIR_Nem_3	37	43	PF02991	0.367
LIG_LIR_Nem_3	8	13	PF02991	0.458
LIG_SH2_CRK	130	134	PF00017	0.447
LIG_SH2_STAT5	122	125	PF00017	0.475
LIG_SH3_3	88	94	PF00018	0.458
LIG_SUMO_SIM_par_1	30	39	PF11976	0.429
LIG_TRAF2_1	36	39	PF00917	0.412
LIG_UBA3_1	63	72	PF00899	0.447
MOD_CK1_1	3	9	PF00069	0.568
MOD_CK2_1	33	39	PF00069	0.434
MOD_N-GLC_1	3	8	PF02516	0.513
MOD_NEK2_1	126	131	PF00069	0.449
MOD_NEK2_1	96	101	PF00069	0.449
MOD_Plk_1	124	130	PF00069	0.460
MOD_Plk_1	15	21	PF00069	0.501
MOD_Plk_4	96	102	PF00069	0.447
MOD_ProDKin_1	90	96	PF00069	0.447
MOD_SUMO_for_1	114	117	PF00179	0.447
MOD_SUMO_for_1	13	16	PF00179	0.481
MOD_SUMO_rev_2	36	43	PF00179	0.363
TRG_AP2beta_CARGO_1	37	47	PF09066	0.392
TRG_DiLeu_BaEn_1	39	44	PF01217	0.377
TRG_DiLeu_LyEn_5	28	33	PF01217	0.399
TRG_ENDOCYTIC_2	10	13	PF00928	0.468
TRG_ENDOCYTIC_2	130	133	PF00928	0.447
TRG_ENDOCYTIC_2	24	27	PF00928	0.399
TRG_ER_diArg_1	47	50	PF00400	0.416
TRG_ER_diArg_1	58	60	PF00400	0.447
TRG_Pf-PMV_PEXEL_1	25	30	PF00026	0.432
TRG_Pf-PMV_PEXEL_1	65	69	PF00026	0.247

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PAQ8	Leptomonas seymouri	94%	100%
A0A0S4IV08	Bodo saltans	81%	100%
A0A1D8PK22	Candida albicans (strain SC5314 / ATCC MYA-2876)	49%	100%
A0A1X0NT57	Trypanosomatidae	89%	100%
A0A3Q8IC71	Leishmania donovani	97%	100%
A0A3R7JWJ1	Trypanosoma rangeli	90%	100%
A0A3R7KCU5	Trypanosoma rangeli	89%	91%
A0A3R7R9F5	Trypanosoma rangeli	89%	100%
A0B9W6	Methanothrix thermoacetophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT)	42%	100%
A0RVX7	Cenarchaeum symbiosum (strain A)	37%	100%
A1RV74	Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3)	42%	95%
A1RWQ5	Thermofilum pendens (strain DSM 2475 / Hrk 5)	42%	100%
A2BMB3	Hyperthermus butylicus (strain DSM 5456 / JCM 9403 / PLM1-5)	45%	100%
A2SPK7	Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z)	38%	100%
A3CT01	Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1)	40%	100%
A3DNB1	Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / JCM 9404 / F1)	44%	100%
A3MTT6	Pyrobaculum calidifontis (strain DSM 21063 / JCM 11548 / VA1)	42%	96%
A4FVX8	Methanococcus maripaludis (strain C5 / ATCC BAA-1333)	37%	94%
A4HZS1	Leishmania infantum	97%	100%
A4WIZ3	Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321 / PZ6)	41%	96%
A4YCX0	Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)	42%	100%
A5UL85	Methanobrevibacter smithii (strain ATCC 35061 / DSM 861 / OCM 144 / PS)	41%	100%
A6UQJ4	Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB)	39%	95%
A6UV64	Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3)	41%	94%
A6VHD6	Methanococcus maripaludis (strain C7 / ATCC BAA-1331)	38%	94%
A7I5P3	Methanoregula boonei (strain DSM 21154 / JCM 14090 / 6A8)	39%	100%
A8AA18	Ignicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125)	43%	100%
A8MC54	Caldivirga maquilingensis (strain ATCC 700844 / DSM 13496 / JCM 10307 / IC-167)	40%	81%
A9A5J1	Nitrosopumilus maritimus (strain SCM1)	41%	100%
A9A9B4	Methanococcus maripaludis (strain C6 / ATCC BAA-1332)	39%	94%
B0R660	Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1)	42%	100%
B1L708	Korarchaeum cryptofilum (strain OPF8)	42%	100%
B1YD00	Pyrobaculum neutrophilum (strain DSM 2338 / JCM 9278 / NBRC 100436 / V24Sta)	42%	96%
B6YSL7	Thermococcus onnurineus (strain NA1)	49%	100%
B9LSS3	Halorubrum lacusprofundi (strain ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34)	42%	100%
C5A282	Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3)	47%	100%
C6A163	Thermococcus sibiricus (strain DSM 12597 / MM 739)	44%	100%
C9ZRJ9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	89%	100%
C9ZRK2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	89%	88%
E9AVM6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	99%	100%
O26114	Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)	39%	100%
O28358	Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)	44%	100%
O59422	Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)	45%	100%
O65059	Picea mariana	60%	100%
O94715	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	58%	99%
P15010	Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)	42%	100%
P20284	Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)	41%	100%
P20342	Xenopus laevis	62%	100%
P31674	Oryza sativa subsp. japonica	59%	99%
P34737	Podospora anserina	62%	100%
P51429	Naegleria gruberi	42%	100%
P54018	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)	45%	100%
P62841	Homo sapiens	64%	100%
P62842	Mesocricetus auratus	64%	100%
P62843	Mus musculus	64%	100%
P62844	Sus scrofa	64%	100%
P62845	Rattus norvegicus	64%	100%
P62846	Gallus gallus	64%	100%
P70066	Xiphophorus maculatus	62%	100%
Q01855	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	51%	100%
Q08112	Arabidopsis thaliana	57%	100%
Q0W1Y5	Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50)	44%	100%
Q12ZU7	Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M)	38%	100%
Q18GF3	Haloquadratum walsbyi (strain DSM 16790 / HBSQ001)	44%	100%
Q2FT35	Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1)	41%	100%
Q2NFW0	Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3)	39%	100%
Q3IMY4	Natronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / JCM 8858 / NBRC 14720 / NCIMB 2260 / Gabara)	44%	100%
Q46G99	Methanosarcina barkeri (strain Fusaro / DSM 804)	42%	100%
Q4JB44	Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)	41%	100%
Q4QBV0	Leishmania major	99%	100%
Q54N17	Dictyostelium discoideum	58%	100%
Q56K10	Bos taurus	64%	100%
Q5JDH3	Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)	48%	100%
Q5RDI7	Pongo abelii	64%	100%
Q6L1C3	Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828)	40%	100%
Q6LX07	Methanococcus maripaludis (strain S2 / LL)	37%	94%
Q74MZ5	Nanoarchaeum equitans (strain Kin4-M)	41%	100%
Q8PV46	Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)	42%	100%
Q8TRU3	Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)	41%	100%
Q8TWP2	Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)	45%	100%
Q8U002	Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)	47%	100%
Q8ZWL4	Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)	41%	96%
Q945U1	Elaeis oleifera	59%	99%
Q975I5	Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)	44%	100%
Q97BX3	Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)	43%	100%
Q9FIX6	Arabidopsis thaliana	57%	100%
Q9FML6	Arabidopsis thaliana	47%	95%
Q9FY64	Arabidopsis thaliana	57%	100%
Q9FY65	Arabidopsis thaliana	58%	100%
Q9FY66	Arabidopsis thaliana	54%	100%
Q9HIR3	Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)	44%	100%
Q9UTQ6	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	58%	99%
Q9UXA3	Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)	42%	100%
Q9V1T9	Pyrococcus abyssi (strain GE5 / Orsay)	45%	100%
Q9XVP0	Caenorhabditis elegans	57%	100%
Q9YF74	Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)	45%	100%