Putative amino acid permease

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

amino acid permease, putative

Species:

Leishmania braziliensis

UniProt:

A4HC75_LEIBR

TriTrypDb:

LbrM.22.0220 , LBRM2903_220007500

Length:

484

Annotations

LeishMANIAdb annotations

An enormously expanded group of various amino acid transporters.. Localization: Cell surface (by feature)

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 8
Forrest at al. (procyclic)	no	yes: 10
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 72

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 5

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 1, no: 176
NetGPI	no	yes: 0, no: 177

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	161
GO:0110165	cellular anatomical entity	1	161
GO:0005634	nucleus	5	1
GO:0005737	cytoplasm	2	1
GO:0005886	plasma membrane	3	1
GO:0020016	ciliary pocket	2	1
GO:0020023	kinetoplast	2	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1

Expansion

Sequence features

A4HC75

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HC75

Function

Biological processes
Term	Name	Level	Count
GO:0003333	amino acid transmembrane transport	5	17
GO:0006810	transport	3	17
GO:0006811	monoatomic ion transport	4	1
GO:0006812	monoatomic cation transport	5	1
GO:0006820	monoatomic anion transport	5	1
GO:0006865	amino acid transport	5	17
GO:0009987	cellular process	1	17
GO:0015711	organic anion transport	5	1
GO:0015802	basic amino acid transport	6	1
GO:0015819	lysine transport	6	1
GO:0015849	organic acid transport	5	17
GO:0046942	carboxylic acid transport	6	1
GO:0051179	localization	1	17
GO:0051234	establishment of localization	2	17
GO:0055085	transmembrane transport	2	17
GO:0071702	organic substance transport	4	17
GO:0071705	nitrogen compound transport	4	17
GO:1903825	organic acid transmembrane transport	3	17
GO:1905039	carboxylic acid transmembrane transport	4	17

Molecular functions
Term	Name	Level	Count
GO:0005215	transporter activity	1	17
GO:0005342	organic acid transmembrane transporter activity	3	17
GO:0008324	monoatomic cation transmembrane transporter activity	4	1
GO:0008509	monoatomic anion transmembrane transporter activity	4	1
GO:0008514	organic anion transmembrane transporter activity	5	1
GO:0015075	monoatomic ion transmembrane transporter activity	3	1
GO:0015171	amino acid transmembrane transporter activity	5	17
GO:0015174	basic amino acid transmembrane transporter activity	6	1
GO:0015179	L-amino acid transmembrane transporter activity	6	17
GO:0015189	L-lysine transmembrane transporter activity	5	1
GO:0022857	transmembrane transporter activity	2	17
GO:0046943	carboxylic acid transmembrane transporter activity	4	17

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	334	338	PF00656	0.288
CLV_NRD_NRD_1	226	228	PF00675	0.276
CLV_NRD_NRD_1	70	72	PF00675	0.487
CLV_PCSK_SKI1_1	155	159	PF00082	0.270
CLV_PCSK_SKI1_1	209	213	PF00082	0.305
CLV_PCSK_SKI1_1	348	352	PF00082	0.471
DOC_CYCLIN_yCln2_LP_2	106	112	PF00134	0.324
DOC_CYCLIN_yCln2_LP_2	219	225	PF00134	0.271
DOC_MAPK_FxFP_2	435	438	PF00069	0.338
DOC_MAPK_gen_1	71	79	PF00069	0.634
DOC_MAPK_MEF2A_6	307	315	PF00069	0.466
DOC_PP1_RVXF_1	153	159	PF00149	0.464
DOC_PP1_RVXF_1	201	208	PF00149	0.332
DOC_PP2B_LxvP_1	106	109	PF13499	0.322
DOC_PP2B_LxvP_1	219	222	PF13499	0.282
DOC_PP2B_LxvP_1	223	226	PF13499	0.282
DOC_PP2B_LxvP_1	413	416	PF13499	0.295
DOC_PP4_FxxP_1	435	438	PF00568	0.303
DOC_USP7_MATH_1	302	306	PF00917	0.499
DOC_USP7_MATH_1	97	101	PF00917	0.338
DOC_WW_Pin1_4	298	303	PF00397	0.466
LIG_14-3-3_CanoR_1	209	215	PF00244	0.291
LIG_14-3-3_CanoR_1	227	233	PF00244	0.449
LIG_14-3-3_CanoR_1	348	357	PF00244	0.292
LIG_Actin_WH2_2	218	235	PF00022	0.272
LIG_Actin_WH2_2	436	453	PF00022	0.327
LIG_BIR_II_1	1	5	PF00653	0.755
LIG_BRCT_BRCA1_1	212	216	PF00533	0.297
LIG_BRCT_BRCA1_1	304	308	PF00533	0.486
LIG_BRCT_BRCA1_1	438	442	PF00533	0.297
LIG_BRCT_BRCA1_1	444	448	PF00533	0.457
LIG_BRCT_BRCA1_1	90	94	PF00533	0.441
LIG_deltaCOP1_diTrp_1	187	192	PF00928	0.335
LIG_deltaCOP1_diTrp_1	386	394	PF00928	0.449
LIG_EH1_1	245	253	PF00400	0.254
LIG_FHA_1	112	118	PF00498	0.240
LIG_FHA_1	119	125	PF00498	0.289
LIG_FHA_1	151	157	PF00498	0.405
LIG_FHA_1	213	219	PF00498	0.319
LIG_FHA_1	475	481	PF00498	0.313
LIG_FHA_1	6	12	PF00498	0.679
LIG_FHA_2	62	68	PF00498	0.600
LIG_LIR_Gen_1	121	130	PF02991	0.350
LIG_LIR_Gen_1	163	172	PF02991	0.381
LIG_LIR_Gen_1	187	193	PF02991	0.241
LIG_LIR_Gen_1	204	214	PF02991	0.248
LIG_LIR_Gen_1	215	223	PF02991	0.289
LIG_LIR_Gen_1	231	242	PF02991	0.428
LIG_LIR_Gen_1	292	302	PF02991	0.270
LIG_LIR_Gen_1	351	362	PF02991	0.276
LIG_LIR_Gen_1	402	410	PF02991	0.285
LIG_LIR_Gen_1	429	440	PF02991	0.402
LIG_LIR_Gen_1	50	60	PF02991	0.701
LIG_LIR_Nem_3	121	126	PF02991	0.331
LIG_LIR_Nem_3	163	168	PF02991	0.328
LIG_LIR_Nem_3	187	192	PF02991	0.209
LIG_LIR_Nem_3	204	210	PF02991	0.247
LIG_LIR_Nem_3	213	219	PF02991	0.282
LIG_LIR_Nem_3	231	237	PF02991	0.439
LIG_LIR_Nem_3	292	298	PF02991	0.301
LIG_LIR_Nem_3	305	311	PF02991	0.409
LIG_LIR_Nem_3	321	327	PF02991	0.305
LIG_LIR_Nem_3	351	357	PF02991	0.262
LIG_LIR_Nem_3	386	390	PF02991	0.463
LIG_LIR_Nem_3	402	406	PF02991	0.279
LIG_LIR_Nem_3	429	435	PF02991	0.330
LIG_LIR_Nem_3	439	444	PF02991	0.378
LIG_LIR_Nem_3	457	462	PF02991	0.461
LIG_LIR_Nem_3	479	484	PF02991	0.365
LIG_MLH1_MIPbox_1	438	442	PF16413	0.296
LIG_NRBOX	405	411	PF00104	0.257
LIG_PCNA_yPIPBox_3	396	404	PF02747	0.504
LIG_Pex14_1	325	329	PF04695	0.315
LIG_Pex14_2	238	242	PF04695	0.300
LIG_Pex14_2	284	288	PF04695	0.288
LIG_Pex14_2	428	432	PF04695	0.360
LIG_Pex14_2	437	441	PF04695	0.359
LIG_SH2_CRK	202	206	PF00017	0.354
LIG_SH2_CRK	347	351	PF00017	0.250
LIG_SH2_PTP2	234	237	PF00017	0.332
LIG_SH2_PTP2	354	357	PF00017	0.317
LIG_SH2_PTP2	359	362	PF00017	0.319
LIG_SH2_SRC	123	126	PF00017	0.305
LIG_SH2_STAP1	133	137	PF00017	0.334
LIG_SH2_STAP1	332	336	PF00017	0.217
LIG_SH2_STAP1	390	394	PF00017	0.523
LIG_SH2_STAT5	123	126	PF00017	0.286
LIG_SH2_STAT5	128	131	PF00017	0.301
LIG_SH2_STAT5	181	184	PF00017	0.280
LIG_SH2_STAT5	234	237	PF00017	0.313
LIG_SH2_STAT5	245	248	PF00017	0.285
LIG_SH2_STAT5	354	357	PF00017	0.335
LIG_SH2_STAT5	359	362	PF00017	0.337
LIG_SH2_STAT5	390	393	PF00017	0.477
LIG_SH3_5	349	353	PF00018	0.335
LIG_SUMO_SIM_anti_2	215	221	PF11976	0.328
LIG_SUMO_SIM_anti_2	402	408	PF11976	0.252
LIG_SUMO_SIM_anti_2	461	466	PF11976	0.299
LIG_SUMO_SIM_par_1	128	134	PF11976	0.304
LIG_TRAF2_1	64	67	PF00917	0.608
LIG_TYR_ITIM	232	237	PF00017	0.464
LIG_TYR_ITIM	243	248	PF00017	0.309
LIG_TYR_ITIM	322	327	PF00017	0.153
LIG_TYR_ITIM	357	362	PF00017	0.309
LIG_TYR_ITSM	119	126	PF00017	0.338
LIG_TYR_ITSM	477	484	PF00017	0.384
LIG_UBA3_1	137	144	PF00899	0.307
LIG_UBA3_1	219	228	PF00899	0.307
LIG_WRC_WIRS_1	268	273	PF05994	0.301
LIG_WRC_WIRS_1	400	405	PF05994	0.340
LIG_WRC_WIRS_1	425	430	PF05994	0.320
MOD_CDK_SPK_2	298	303	PF00069	0.469
MOD_CK1_1	405	411	PF00069	0.335
MOD_CK2_1	61	67	PF00069	0.625
MOD_Cter_Amidation	69	72	PF01082	0.396
MOD_GlcNHglycan	113	117	PF01048	0.453
MOD_GlcNHglycan	189	192	PF01048	0.432
MOD_GlcNHglycan	253	256	PF01048	0.355
MOD_GlcNHglycan	263	266	PF01048	0.502
MOD_GlcNHglycan	444	447	PF01048	0.260
MOD_GlcNHglycan	90	93	PF01048	0.245
MOD_GSK3_1	142	149	PF00069	0.447
MOD_GSK3_1	187	194	PF00069	0.280
MOD_GSK3_1	298	305	PF00069	0.487
MOD_GSK3_1	424	431	PF00069	0.187
MOD_N-GLC_1	298	303	PF02516	0.243
MOD_N-GLC_1	61	66	PF02516	0.482
MOD_NEK2_1	112	117	PF00069	0.240
MOD_NEK2_1	289	294	PF00069	0.311
MOD_NEK2_1	318	323	PF00069	0.328
MOD_NEK2_1	37	42	PF00069	0.674
MOD_NEK2_1	424	429	PF00069	0.291
MOD_NEK2_1	442	447	PF00069	0.462
MOD_NEK2_1	458	463	PF00069	0.258
MOD_NEK2_1	474	479	PF00069	0.268
MOD_NEK2_1	96	101	PF00069	0.310
MOD_NEK2_2	118	123	PF00069	0.308
MOD_NEK2_2	128	133	PF00069	0.311
MOD_NEK2_2	13	18	PF00069	0.537
MOD_Plk_1	37	43	PF00069	0.581
MOD_Plk_1	5	11	PF00069	0.692
MOD_Plk_2-3	61	67	PF00069	0.606
MOD_Plk_4	118	124	PF00069	0.289
MOD_Plk_4	128	134	PF00069	0.290
MOD_Plk_4	13	19	PF00069	0.670
MOD_Plk_4	212	218	PF00069	0.310
MOD_Plk_4	233	239	PF00069	0.434
MOD_Plk_4	313	319	PF00069	0.280
MOD_Plk_4	339	345	PF00069	0.242
MOD_Plk_4	399	405	PF00069	0.259
MOD_Plk_4	428	434	PF00069	0.300
MOD_Plk_4	436	442	PF00069	0.368
MOD_Plk_4	476	482	PF00069	0.237
MOD_Plk_4	5	11	PF00069	0.756
MOD_ProDKin_1	298	304	PF00069	0.466
MOD_SUMO_rev_2	445	453	PF00179	0.344
TRG_DiLeu_BaEn_1	310	315	PF01217	0.342
TRG_DiLeu_BaLyEn_6	133	138	PF01217	0.361
TRG_DiLeu_BaLyEn_6	152	157	PF01217	0.463
TRG_ENDOCYTIC_2	123	126	PF00928	0.317
TRG_ENDOCYTIC_2	202	205	PF00928	0.354
TRG_ENDOCYTIC_2	234	237	PF00928	0.311
TRG_ENDOCYTIC_2	245	248	PF00928	0.313
TRG_ENDOCYTIC_2	295	298	PF00928	0.417
TRG_ENDOCYTIC_2	324	327	PF00928	0.296
TRG_ENDOCYTIC_2	332	335	PF00928	0.299
TRG_ENDOCYTIC_2	347	350	PF00928	0.245
TRG_ENDOCYTIC_2	354	357	PF00928	0.307
TRG_ENDOCYTIC_2	359	362	PF00928	0.308
TRG_ENDOCYTIC_2	456	459	PF00928	0.448
TRG_ENDOCYTIC_2	481	484	PF00928	0.349
TRG_Pf-PMV_PEXEL_1	348	352	PF00026	0.514

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P285	Leptomonas seymouri	34%	98%
A0A0N0P5D2	Leptomonas seymouri	40%	100%
A0A0N0P613	Leptomonas seymouri	30%	100%
A0A0N0P6F5	Leptomonas seymouri	26%	100%
A0A0N0P6F6	Leptomonas seymouri	69%	100%
A0A0N0P8T9	Leptomonas seymouri	40%	97%
A0A0N0P955	Leptomonas seymouri	40%	100%
A0A0N1I2L5	Leptomonas seymouri	40%	100%
A0A0N1I3F8	Leptomonas seymouri	43%	91%
A0A0N1I3H4	Leptomonas seymouri	42%	88%
A0A0N1I8K7	Leptomonas seymouri	39%	99%
A0A0N1I8W4	Leptomonas seymouri	31%	99%
A0A0N1I9T3	Leptomonas seymouri	43%	100%
A0A0N1IAJ0	Leptomonas seymouri	23%	100%
A0A0N1IMP2	Leptomonas seymouri	42%	96%
A0A0N1PA98	Leptomonas seymouri	36%	79%
A0A0N1PBP2	Leptomonas seymouri	40%	98%
A0A0N1PFD1	Leptomonas seymouri	42%	97%
A0A0S4IV32	Bodo saltans	25%	99%
A0A0S4JBX6	Bodo saltans	26%	91%
A0A0S4JHM8	Bodo saltans	28%	100%
A0A0S4JPU4	Bodo saltans	22%	99%
A0A0S4JQ87	Bodo saltans	31%	100%
A0A0S4JU02	Bodo saltans	36%	100%
A0A1X0NJR7	Trypanosomatidae	47%	98%
A0A1X0NKS5	Trypanosomatidae	42%	100%
A0A1X0NKV2	Trypanosomatidae	42%	97%
A0A1X0NKW7	Trypanosomatidae	44%	100%
A0A1X0NLA5	Trypanosomatidae	23%	100%
A0A1X0NNX9	Trypanosomatidae	57%	100%
A0A1X0NPV3	Trypanosomatidae	39%	100%
A0A1X0NQH3	Trypanosomatidae	39%	100%
A0A1X0NR26	Trypanosomatidae	41%	100%
A0A1X0NRL3	Trypanosomatidae	45%	100%
A0A1X0NRL7	Trypanosomatidae	41%	100%
A0A1X0NYI3	Trypanosomatidae	38%	97%
A0A1X0P4S1	Trypanosomatidae	24%	100%
A0A1X0P814	Trypanosomatidae	43%	99%
A0A1X0P9N8	Trypanosomatidae	32%	100%
A0A3Q8ICL1	Leishmania donovani	35%	80%
A0A3Q8ID74	Leishmania donovani	40%	90%
A0A3Q8IDG8	Leishmania donovani	40%	100%
A0A3Q8IEP8	Leishmania donovani	41%	89%
A0A3Q8IFZ0	Leishmania donovani	39%	95%
A0A3Q8IG00	Leishmania donovani	39%	100%
A0A3Q8IGE6	Leishmania donovani	35%	82%
A0A3Q8IHG8	Leishmania donovani	39%	97%
A0A3Q8IJH2	Leishmania donovani	43%	100%
A0A3Q8IJX8	Leishmania donovani	37%	100%
A0A3Q8ILE0	Leishmania donovani	81%	100%
A0A3Q8IN54	Leishmania donovani	27%	100%
A0A3Q8IQG8	Leishmania donovani	32%	98%
A0A3R7JSA0	Trypanosoma rangeli	40%	100%
A0A3R7KDS3	Trypanosoma rangeli	40%	100%
A0A3R7MQD8	Trypanosoma rangeli	21%	100%
A0A3R7MWF1	Trypanosoma rangeli	25%	100%
A0A3R7N1H9	Trypanosoma rangeli	38%	99%
A0A3R7N2A2	Trypanosoma rangeli	40%	100%
A0A3R7R2W8	Trypanosoma rangeli	38%	100%
A0A3R7RFB5	Trypanosoma rangeli	56%	95%
A0A3R7RQX3	Trypanosoma rangeli	42%	100%
A0A3S5H6T4	Leishmania donovani	40%	96%
A0A3S5H7P4	Leishmania donovani	40%	95%
A0A3S5ISG3	Trypanosoma rangeli	45%	98%
A0A3S7WQ39	Leishmania donovani	42%	99%
A0A3S7X443	Leishmania donovani	40%	100%
A0A3S7X458	Leishmania donovani	40%	97%
A0A3S7X4A1	Leishmania donovani	37%	100%
A0A3S7X4L2	Leishmania donovani	36%	80%
A0A3S7X4N4	Leishmania donovani	36%	80%
A0A3S7X4P0	Leishmania donovani	36%	80%
A0A3S7XA86	Leishmania donovani	26%	100%
A0A3S7XCE3	Leishmania donovani	22%	100%
A0A422MW74	Trypanosoma rangeli	36%	94%
A0A422N5W8	Trypanosoma rangeli	24%	100%
A0A422N608	Trypanosoma rangeli	38%	99%
A0A422NBM3	Trypanosoma rangeli	39%	100%
A0A422NBQ2	Trypanosoma rangeli	41%	100%
A0A422NZS1	Trypanosoma rangeli	42%	100%
A1YG32	Pan paniscus	24%	96%
A2VCW5	Rattus norvegicus	24%	100%
A2VE31	Bos taurus	24%	96%
A4H565	Leishmania braziliensis	38%	100%
A4HFJ2	Leishmania braziliensis	40%	90%
A4HFT5	Leishmania braziliensis	38%	100%
A4HJ06	Leishmania braziliensis	38%	90%
A4HJ07	Leishmania braziliensis	40%	97%
A4HJ09	Leishmania braziliensis	38%	97%
A4HJ10	Leishmania braziliensis	39%	95%
A4HJ35	Leishmania braziliensis	44%	100%
A4HJ36	Leishmania braziliensis	39%	94%
A4HJ37	Leishmania braziliensis	41%	90%
A4HJ63	Leishmania braziliensis	39%	100%
A4HJF8	Leishmania braziliensis	38%	79%
A4HJF9	Leishmania braziliensis	38%	83%
A4HJG1	Leishmania braziliensis	38%	83%
A4HJG3	Leishmania braziliensis	37%	79%
A4HJG5	Leishmania braziliensis	38%	79%
A4HKQ7	Leishmania braziliensis	41%	100%
A4HNJ6	Leishmania braziliensis	26%	100%
A4HNJ7	Leishmania braziliensis	27%	100%
A4HNQ0	Leishmania braziliensis	27%	100%
A4HTE2	Leishmania infantum	38%	99%
A4HZQ0	Leishmania infantum	81%	100%
A4I2V2	Leishmania infantum	38%	82%
A4I6F1	Leishmania infantum	40%	95%
A4I6F2	Leishmania infantum	41%	89%
A4I6I1	Leishmania infantum	37%	100%
A4I6J8	Leishmania infantum	39%	90%
A4I6J9	Leishmania infantum	40%	100%
A4I6K0	Leishmania infantum	39%	95%
A4I6L3	Leishmania infantum	39%	100%
A4I6L4	Leishmania infantum	37%	100%
A4I6W4	Leishmania infantum	36%	80%
A4I887	Leishmania infantum	43%	100%
A4IC53	Leishmania infantum	26%	100%
A4IC66	Leishmania infantum	27%	100%
A4ICC3	Leishmania infantum	22%	100%
A4ICU5	Leishmania infantum	32%	98%
A6NNN8	Homo sapiens	23%	100%
A7E3U5	Bos taurus	24%	100%
C9ZMB9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	100%
C9ZMD1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	99%
C9ZMD2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	100%
C9ZMD3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	99%
C9ZMD4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
C9ZN51	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	100%
C9ZN59	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	100%
C9ZN60	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	100%
C9ZVS1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	92%
C9ZVS2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	90%
C9ZVS3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	91%
C9ZWQ7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	100%
C9ZWQ8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
C9ZWQ9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	100%
C9ZWR0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	100%
C9ZWR1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	89%
C9ZWR7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
C9ZWX2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	100%
C9ZWX3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	100%
C9ZWX4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	100%
C9ZWX5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	100%
C9ZWX6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
C9ZWX7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
C9ZWY0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	100%
C9ZWY1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	100%
D0A362	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	100%
D0AAF6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
D0AAF8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
D0AAG7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	98%
D0AAG8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	98%
E8NHF9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	42%	100%
E8NHS7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	83%
E9AD44	Leishmania major	40%	100%
E9AD45	Leishmania major	38%	100%
E9ADD7	Leishmania major	40%	97%
E9AG08	Leishmania major	27%	100%
E9AG09	Leishmania major	27%	100%
E9AHD7	Leishmania infantum	40%	97%
E9AHD9	Leishmania infantum	40%	90%
E9AHK8	Leishmania infantum	36%	100%
E9AHL1	Leishmania infantum	35%	80%
E9AHL2	Leishmania infantum	36%	100%
E9AHL3	Leishmania infantum	36%	80%
E9ALD5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	41%	99%
E9ASF9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	98%
E9AUB8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	100%
E9AVK6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	78%	100%
E9AYW8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	97%
E9AYW9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	43%	90%
E9AZ62	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	100%
E9B1I4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	44%	100%
E9B1I6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	38%	95%
E9B1K7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	42%	100%
E9B1K8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	38%	95%
E9B1K9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	43%	88%
E9B1N8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	37%	100%
E9B1N9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	37%	100%
E9B1Y0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	36%	79%
E9B345	Leishmania mexicana (strain MHOM/GT/2001/U1103)	44%	100%
E9B761	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
E9B762	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	100%
F4ILY9	Arabidopsis thaliana	24%	100%
F4IUW3	Arabidopsis thaliana	25%	88%
F4IZW8	Arabidopsis thaliana	24%	92%
F4JE35	Arabidopsis thaliana	26%	90%
F4KBM7	Arabidopsis thaliana	25%	100%
G3UVW3	Mus musculus	26%	100%
O22719	Arabidopsis thaliana	24%	100%
O74327	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	27%	100%
O80668	Arabidopsis thaliana	22%	90%
P34479	Caenorhabditis elegans	22%	100%
P36062	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	22%	70%
P39981	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	23%	100%
Q0WQJ3	Arabidopsis thaliana	26%	100%
Q1PER9	Arabidopsis thaliana	23%	92%
Q28HE5	Xenopus tropicalis	27%	100%
Q28I47	Xenopus tropicalis	21%	100%
Q3U1J0	Mus musculus	24%	100%
Q4Q072	Leishmania major	22%	95%
Q4Q236	Leishmania major	32%	100%
Q4Q509	Leishmania major	39%	100%
Q4Q680	Leishmania major	34%	80%
Q4Q682	Leishmania major	37%	82%
Q4Q683	Leishmania major	34%	80%
Q4Q6H5	Leishmania major	39%	100%
Q4Q6K5	Leishmania major	40%	100%
Q4Q6K6	Leishmania major	39%	100%
Q4Q6M8	Leishmania major	39%	100%
Q4Q6M9	Leishmania major	39%	100%
Q4Q6N0	Leishmania major	39%	100%
Q4Q6N1	Leishmania major	37%	100%
Q4QBX3	Leishmania major	79%	100%
Q4QIH0	Leishmania major	37%	100%
Q503G8	Danio rerio	28%	100%
Q5E9S9	Bos taurus	25%	100%
Q5F468	Gallus gallus	26%	97%
Q5HZH7	Mus musculus	23%	100%
Q5R443	Pongo abelii	26%	99%
Q5R9F5	Pongo abelii	24%	100%
Q5RE87	Pongo abelii	24%	88%
Q5SPB1	Danio rerio	23%	96%
Q5XH90	Xenopus tropicalis	24%	98%
Q6DEL1	Danio rerio	26%	100%
Q6DFE7	Xenopus laevis	26%	100%
Q6JWR2	Rattus norvegicus	25%	100%
Q6WWW3	Rattus norvegicus	26%	100%
Q8BWH0	Mus musculus	25%	100%
Q8CFE6	Mus musculus	25%	96%
Q8GYS4	Arabidopsis thaliana	26%	88%
Q8IZM9	Homo sapiens	27%	100%
Q8K2P7	Mus musculus	24%	100%
Q8LPF4	Arabidopsis thaliana	27%	92%
Q8WUX1	Homo sapiens	26%	100%
Q969I6	Homo sapiens	24%	88%
Q96QD8	Homo sapiens	24%	96%
Q99624	Homo sapiens	26%	96%
Q9DCP2	Mus musculus	26%	96%
Q9EQ25	Rattus norvegicus	23%	88%
Q9FKS8	Arabidopsis thaliana	25%	100%
Q9H2H9	Homo sapiens	26%	99%
Q9JHE5	Rattus norvegicus	26%	96%
Q9JHZ9	Rattus norvegicus	26%	96%
Q9JM15	Rattus norvegicus	25%	100%
Q9LI61	Arabidopsis thaliana	26%	100%
Q9LXF8	Arabidopsis thaliana	23%	100%
Q9LYM2	Arabidopsis thaliana	24%	100%
Q9M8L9	Arabidopsis thaliana	24%	99%
Q9NVC3	Homo sapiens	24%	100%
Q9SF09	Arabidopsis thaliana	25%	100%
Q9SVG0	Arabidopsis thaliana	25%	100%
V5AXD0	Trypanosoma cruzi	25%	100%
V5AZP2	Trypanosoma cruzi	38%	80%
V5B9A6	Trypanosoma cruzi	44%	100%
V5BA72	Trypanosoma cruzi	45%	100%
V5BH70	Trypanosoma cruzi	53%	100%
V5BIJ1	Trypanosoma cruzi	41%	86%
V5BMG4	Trypanosoma cruzi	41%	100%
V5BTX5	Trypanosoma cruzi	25%	96%
V5D7K9	Trypanosoma cruzi	44%	100%
V5DCG4	Trypanosoma cruzi	38%	100%
V5DKR4	Trypanosoma cruzi	39%	100%