Perilipin-3-like

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Perilipin-3-like

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HC71_LEIBR

TriTrypDb:

LbrM.22.0180 , LBRM2903_220007100

Length:

199

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HC71

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HC71

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	71	75	PF00656	0.552
CLV_NRD_NRD_1	194	196	PF00675	0.556
CLV_NRD_NRD_1	40	42	PF00675	0.454
CLV_PCSK_SKI1_1	134	138	PF00082	0.551
DEG_Nend_UBRbox_3	1	3	PF02207	0.575
DOC_USP7_MATH_1	58	62	PF00917	0.623
DOC_USP7_MATH_1	65	69	PF00917	0.614
LIG_14-3-3_CanoR_1	125	131	PF00244	0.434
LIG_14-3-3_CanoR_1	13	22	PF00244	0.644
LIG_14-3-3_CanoR_1	66	73	PF00244	0.577
LIG_14-3-3_CanoR_1	84	94	PF00244	0.531
LIG_FHA_1	125	131	PF00498	0.434
LIG_FHA_1	170	176	PF00498	0.392
LIG_LIR_Gen_1	106	116	PF02991	0.271
LIG_LIR_Nem_3	106	112	PF02991	0.271
LIG_LIR_Nem_3	176	182	PF02991	0.371
LIG_RPA_C_Fungi	61	73	PF08784	0.512
LIG_SH2_CRK	179	183	PF00017	0.393
LIG_SH2_GRB2like	94	97	PF00017	0.422
LIG_SH2_SRC	47	50	PF00017	0.488
LIG_SH2_STAT5	121	124	PF00017	0.322
LIG_SH2_STAT5	179	182	PF00017	0.442
LIG_SH2_STAT5	36	39	PF00017	0.519
LIG_SH2_STAT5	47	50	PF00017	0.530
LIG_SH2_STAT5	7	10	PF00017	0.564
LIG_SH2_STAT5	94	97	PF00017	0.511
LIG_SH3_3	159	165	PF00018	0.575
LIG_SUMO_SIM_par_1	171	176	PF11976	0.396
MOD_CK1_1	61	67	PF00069	0.467
MOD_CK1_1	68	74	PF00069	0.509
MOD_GlcNHglycan	131	134	PF01048	0.488
MOD_GlcNHglycan	153	156	PF01048	0.402
MOD_GlcNHglycan	49	52	PF01048	0.484
MOD_GlcNHglycan	56	59	PF01048	0.486
MOD_GlcNHglycan	63	66	PF01048	0.497
MOD_GlcNHglycan	67	70	PF01048	0.496
MOD_GSK3_1	169	176	PF00069	0.517
MOD_GSK3_1	54	61	PF00069	0.656
MOD_GSK3_1	78	85	PF00069	0.689
MOD_NEK2_1	101	106	PF00069	0.525
MOD_NEK2_1	115	120	PF00069	0.244
MOD_PIKK_1	124	130	PF00454	0.523
MOD_PIKK_1	184	190	PF00454	0.576
MOD_PIKK_1	88	94	PF00454	0.569
MOD_PKA_2	124	130	PF00069	0.523
MOD_PKA_2	65	71	PF00069	0.456
MOD_PKA_2	85	91	PF00069	0.365
MOD_Plk_4	115	121	PF00069	0.285
MOD_Plk_4	169	175	PF00069	0.419
MOD_Plk_4	3	9	PF00069	0.573
MOD_SUMO_rev_2	16	20	PF00179	0.545
TRG_ENDOCYTIC_2	179	182	PF00928	0.392
TRG_ENDOCYTIC_2	98	101	PF00928	0.696
TRG_ER_diArg_1	83	86	PF00400	0.409
TRG_ER_diLys_1	196	199	PF00400	0.443
TRG_NES_CRM1_1	21	35	PF08389	0.398

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBW9	Leptomonas seymouri	54%	79%
A0A3Q8IE48	Leishmania donovani	79%	77%
A4HZP6	Leishmania infantum	79%	77%
E9AVK2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	78%	77%
Q4QBX7	Leishmania major	77%	100%