SP-RING-type domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HC22_LEIBR

TriTrypDb:

LbrM.21.1890 , LBRM2903_210024800

Length:

136


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0031974	membrane-enclosed lumen	2	1
GO:0031981	nuclear lumen	5	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0043233	organelle lumen	3	1
GO:0070013	intracellular organelle lumen	4	1
GO:0097014	ciliary plasm	5	1
GO:0099568	cytoplasmic region	3	1
GO:0110165	cellular anatomical entity	1	1

A4HC22

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HC22


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	104	106	PF00675	0.544
CLV_NRD_NRD_1	99	101	PF00675	0.516
CLV_PCSK_KEX2_1	104	106	PF00082	0.520
CLV_PCSK_PC7_1	100	106	PF00082	0.436
CLV_PCSK_SKI1_1	116	120	PF00082	0.440
CLV_PCSK_SKI1_1	8	12	PF00082	0.611
CLV_Separin_Metazoa	120	124	PF03568	0.391
DOC_USP7_MATH_1	32	36	PF00917	0.399
LIG_14-3-3_CanoR_1	100	104	PF00244	0.455
LIG_14-3-3_CanoR_1	116	121	PF00244	0.443
LIG_14-3-3_CanoR_1	15	20	PF00244	0.545
LIG_14-3-3_CanoR_1	59	63	PF00244	0.427
LIG_BIR_II_1	1	5	PF00653	0.608
LIG_DLG_GKlike_1	15	22	PF00625	0.536
LIG_FHA_1	117	123	PF00498	0.565
LIG_FHA_2	9	15	PF00498	0.536
LIG_LIR_Apic_2	82	88	PF02991	0.435
LIG_NRBOX	21	27	PF00104	0.436
LIG_SH3_3	115	121	PF00018	0.648
LIG_SUMO_SIM_anti_2	18	24	PF11976	0.588
LIG_TRAF2_1	11	14	PF00917	0.555
MOD_CK1_1	4	10	PF00069	0.486
MOD_CK2_1	32	38	PF00069	0.394
MOD_CK2_1	8	14	PF00069	0.656
MOD_GlcNHglycan	1	4	PF01048	0.629
MOD_GlcNHglycan	34	37	PF01048	0.366
MOD_GSK3_1	108	115	PF00069	0.546
MOD_GSK3_1	4	11	PF00069	0.603
MOD_GSK3_1	54	61	PF00069	0.472
MOD_GSK3_1	68	75	PF00069	0.391
MOD_GSK3_1	89	96	PF00069	0.367
MOD_N-GLC_1	93	98	PF02516	0.356
MOD_NEK2_1	1	6	PF00069	0.619
MOD_NEK2_1	25	30	PF00069	0.498
MOD_NEK2_1	89	94	PF00069	0.416
MOD_NEK2_2	99	104	PF00069	0.522
MOD_PIKK_1	1	7	PF00454	0.586
MOD_PIKK_1	79	85	PF00454	0.397
MOD_PKA_2	112	118	PF00069	0.547
MOD_PKA_2	58	64	PF00069	0.403
MOD_PKA_2	79	85	PF00069	0.559
MOD_PKA_2	99	105	PF00069	0.391
MOD_Plk_1	54	60	PF00069	0.549
MOD_Plk_1	93	99	PF00069	0.384
MOD_Plk_4	58	64	PF00069	0.403
TRG_ER_diArg_1	103	105	PF00400	0.520
TRG_Pf-PMV_PEXEL_1	8	13	PF00026	0.610


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P421	Leptomonas seymouri	42%	89%
A0A3Q8IE24	Leishmania donovani	69%	100%
A4HZG5	Leishmania infantum	67%	100%
E9AVF5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	69%	86%
Q4QC24	Leishmania major	68%	100%