LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HC11_LEIBR
TriTrypDb:
LbrM.21.1770 , LBRM2903_210024100
Length:
144

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HC11
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HC11

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 138 140 PF00675 0.665
CLV_NRD_NRD_1 19 21 PF00675 0.723
CLV_NRD_NRD_1 28 30 PF00675 0.675
CLV_PCSK_KEX2_1 137 139 PF00082 0.780
CLV_PCSK_KEX2_1 19 21 PF00082 0.729
CLV_PCSK_KEX2_1 28 30 PF00082 0.664
CLV_PCSK_SKI1_1 99 103 PF00082 0.468
CLV_Separin_Metazoa 86 90 PF03568 0.352
DEG_APCC_DBOX_1 36 44 PF00400 0.524
DOC_PP1_RVXF_1 119 126 PF00149 0.537
DOC_USP7_MATH_1 24 28 PF00917 0.670
DOC_USP7_MATH_1 55 59 PF00917 0.763
DOC_USP7_MATH_1 73 77 PF00917 0.399
DOC_USP7_MATH_1 8 12 PF00917 0.658
DOC_WW_Pin1_4 127 132 PF00397 0.482
DOC_WW_Pin1_4 61 66 PF00397 0.649
LIG_14-3-3_CanoR_1 118 124 PF00244 0.533
LIG_14-3-3_CanoR_1 80 88 PF00244 0.354
LIG_BIR_II_1 1 5 PF00653 0.564
LIG_LIR_Gen_1 113 123 PF02991 0.643
LIG_LIR_Nem_3 113 119 PF02991 0.643
LIG_SH2_CRK 91 95 PF00017 0.507
LIG_SH3_3 18 24 PF00018 0.654
LIG_SH3_3 69 75 PF00018 0.667
LIG_TRAF2_1 83 86 PF00917 0.500
MOD_CK1_1 11 17 PF00069 0.558
MOD_CK2_1 108 114 PF00069 0.583
MOD_Cter_Amidation 135 138 PF01082 0.668
MOD_GlcNHglycan 1 4 PF01048 0.623
MOD_GlcNHglycan 10 13 PF01048 0.511
MOD_GlcNHglycan 110 113 PF01048 0.499
MOD_GlcNHglycan 16 19 PF01048 0.523
MOD_GlcNHglycan 45 48 PF01048 0.600
MOD_GSK3_1 49 56 PF00069 0.723
MOD_GSK3_1 57 64 PF00069 0.656
MOD_GSK3_1 8 15 PF00069 0.589
MOD_NEK2_1 95 100 PF00069 0.513
MOD_PIKK_1 81 87 PF00454 0.350
MOD_ProDKin_1 127 133 PF00069 0.486
MOD_ProDKin_1 61 67 PF00069 0.647
TRG_ENDOCYTIC_2 91 94 PF00928 0.506
TRG_ER_diArg_1 137 139 PF00400 0.544
TRG_ER_diArg_1 19 21 PF00400 0.688
TRG_ER_diArg_1 28 30 PF00400 0.664

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8IAG5 Leishmania donovani 73% 99%
A4HZF2 Leishmania infantum 73% 99%
E9AVE8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 74% 99%
Q4QC31 Leishmania major 69% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS