LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Laminin N-terminal domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Laminin N-terminal domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HBY8_LEIBR
TriTrypDb:
LbrM.21.1540 , LBRM2903_210021000 *
Length:
162

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. yes yes: 25
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 16
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 6, no: 4
NetGPI no yes: 0, no: 10
Cellular components
Term Name Level Count
GO:0016020 membrane 2 2
GO:0110165 cellular anatomical entity 1 2

Expansion

Sequence features

A4HBY8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HBY8

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 112 116 PF00656 0.298
CLV_NRD_NRD_1 11 13 PF00675 0.595
CLV_PCSK_KEX2_1 11 13 PF00082 0.588
DEG_APCC_DBOX_1 132 140 PF00400 0.358
DOC_MAPK_gen_1 101 108 PF00069 0.424
DOC_USP7_MATH_1 26 30 PF00917 0.640
LIG_14-3-3_CanoR_1 126 131 PF00244 0.252
LIG_14-3-3_CanoR_1 22 31 PF00244 0.610
LIG_14-3-3_CanoR_1 6 11 PF00244 0.784
LIG_BRCT_BRCA1_1 151 155 PF00533 0.376
LIG_FHA_2 139 145 PF00498 0.455
LIG_FHA_2 95 101 PF00498 0.378
LIG_LIR_Nem_3 144 150 PF02991 0.370
LIG_LIR_Nem_3 152 158 PF02991 0.335
LIG_LIR_Nem_3 28 33 PF02991 0.300
LIG_SH3_3 17 23 PF00018 0.614
MOD_CK1_1 134 140 PF00069 0.465
MOD_CK1_1 25 31 PF00069 0.615
MOD_CK1_1 86 92 PF00069 0.421
MOD_CK2_1 138 144 PF00069 0.405
MOD_GlcNHglycan 135 139 PF01048 0.637
MOD_GlcNHglycan 151 154 PF01048 0.580
MOD_GlcNHglycan 24 27 PF01048 0.467
MOD_GSK3_1 134 141 PF00069 0.341
MOD_GSK3_1 22 29 PF00069 0.691
MOD_PK_1 126 132 PF00069 0.406
MOD_PKA_2 5 11 PF00069 0.755
MOD_PKA_2 58 64 PF00069 0.312
TRG_DiLeu_BaLyEn_6 28 33 PF01217 0.233
TRG_ER_diArg_1 10 12 PF00400 0.776

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1HSR8 Leptomonas seymouri 52% 100%
A0A0S4JJA7 Bodo saltans 46% 100%
A0A1X0NXY8 Trypanosomatidae 39% 100%
A0A3R7KIY1 Trypanosoma rangeli 42% 100%
A0A3S7WWM3 Leishmania donovani 67% 100%
A4HZD0 Leishmania infantum 67% 100%
D0A154 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
E9AVB7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 66% 100%
Q4QC63 Leishmania major 64% 99%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS