Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HBY3_LEIBR

TriTrypDb:

LbrM.21.1480 , LBRM2903_210020300

Length:

766

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HBY3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HBY3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	720	724	PF00656	0.871
CLV_C14_Caspase3-7	740	744	PF00656	0.460
CLV_NRD_NRD_1	183	185	PF00675	0.874
CLV_NRD_NRD_1	273	275	PF00675	0.861
CLV_NRD_NRD_1	337	339	PF00675	0.887
CLV_NRD_NRD_1	680	682	PF00675	0.859
CLV_PCSK_KEX2_1	183	185	PF00082	0.874
CLV_PCSK_KEX2_1	264	266	PF00082	0.871
CLV_PCSK_KEX2_1	273	275	PF00082	0.704
CLV_PCSK_KEX2_1	283	285	PF00082	0.551
CLV_PCSK_KEX2_1	337	339	PF00082	0.887
CLV_PCSK_KEX2_1	680	682	PF00082	0.859
CLV_PCSK_PC1ET2_1	264	266	PF00082	0.871
CLV_PCSK_PC1ET2_1	283	285	PF00082	0.551
CLV_PCSK_SKI1_1	273	277	PF00082	0.859
DEG_Nend_Nbox_1	1	3	PF02207	0.705
DEG_SCF_FBW7_1	209	214	PF00400	0.852
DEG_SPOP_SBC_1	216	220	PF00917	0.860
DEG_SPOP_SBC_1	230	234	PF00917	0.635
DEG_SPOP_SBC_1	757	761	PF00917	0.869
DOC_CDC14_PxL_1	244	252	PF14671	0.876
DOC_CYCLIN_RxL_1	328	339	PF00134	0.888
DOC_CYCLIN_yCln2_LP_2	130	136	PF00134	0.706
DOC_CYCLIN_yCln2_LP_2	366	372	PF00134	0.786
DOC_MAPK_gen_1	287	297	PF00069	0.878
DOC_MAPK_JIP1_4	626	632	PF00069	0.831
DOC_PP1_RVXF_1	710	717	PF00149	0.838
DOC_PP2B_LxvP_1	188	191	PF13499	0.833
DOC_PP2B_LxvP_1	366	369	PF13499	0.786
DOC_PP2B_LxvP_1	462	465	PF13499	0.650
DOC_PP2B_LxvP_1	482	485	PF13499	0.410
DOC_PP2B_LxvP_1	706	709	PF13499	0.805
DOC_PP4_FxxP_1	437	440	PF00568	0.714
DOC_SPAK_OSR1_1	596	600	PF12202	0.608
DOC_USP7_MATH_1	114	118	PF00917	0.701
DOC_USP7_MATH_1	212	216	PF00917	0.866
DOC_USP7_MATH_1	226	230	PF00917	0.636
DOC_USP7_MATH_1	285	289	PF00917	0.873
DOC_USP7_MATH_1	319	323	PF00917	0.888
DOC_USP7_MATH_1	342	346	PF00917	0.868
DOC_USP7_MATH_1	395	399	PF00917	0.867
DOC_USP7_MATH_1	465	469	PF00917	0.660
DOC_USP7_MATH_1	528	532	PF00917	0.672
DOC_USP7_MATH_1	625	629	PF00917	0.829
DOC_USP7_MATH_1	631	635	PF00917	0.711
DOC_USP7_MATH_1	675	679	PF00917	0.863
DOC_USP7_MATH_1	693	697	PF00917	0.515
DOC_USP7_MATH_1	757	761	PF00917	0.869
DOC_WW_Pin1_4	159	164	PF00397	0.820
DOC_WW_Pin1_4	168	173	PF00397	0.688
DOC_WW_Pin1_4	207	212	PF00397	0.854
DOC_WW_Pin1_4	22	27	PF00397	0.694
DOC_WW_Pin1_4	30	35	PF00397	0.603
DOC_WW_Pin1_4	356	361	PF00397	0.858
DOC_WW_Pin1_4	513	518	PF00397	0.598
LIG_14-3-3_CanoR_1	287	297	PF00244	0.878
LIG_14-3-3_CanoR_1	320	324	PF00244	0.888
LIG_14-3-3_CanoR_1	378	386	PF00244	0.876
LIG_14-3-3_CanoR_1	42	50	PF00244	0.708
LIG_14-3-3_CanoR_1	574	582	PF00244	0.798
LIG_14-3-3_CanoR_1	684	688	PF00244	0.845
LIG_Actin_WH2_2	534	551	PF00022	0.629
LIG_APCC_ABBA_1	495	500	PF00400	0.741
LIG_APCC_ABBA_1	749	754	PF00400	0.830
LIG_BIR_III_2	257	261	PF00653	0.875
LIG_BRCT_BRCA1_1	15	19	PF00533	0.708
LIG_CtBP_PxDLS_1	29	33	PF00389	0.699
LIG_EVH1_1	244	248	PF00568	0.869
LIG_FAT_LD_1	742	750	PF03623	0.810
LIG_FHA_1	208	214	PF00498	0.854
LIG_FHA_1	25	31	PF00498	0.692
LIG_FHA_1	356	362	PF00498	0.860
LIG_FHA_1	465	471	PF00498	0.644
LIG_FHA_2	252	258	PF00498	0.886
LIG_FHA_2	357	363	PF00498	0.861
LIG_FHA_2	443	449	PF00498	0.684
LIG_FHA_2	552	558	PF00498	0.782
LIG_FHA_2	657	663	PF00498	0.752
LIG_FHA_2	738	744	PF00498	0.820
LIG_IBAR_NPY_1	750	752	PF08397	0.822
LIG_LIR_Apic_2	434	440	PF02991	0.733
LIG_LIR_Apic_2	472	478	PF02991	0.666
LIG_LIR_Gen_1	9	20	PF02991	0.702
LIG_LIR_Nem_3	651	655	PF02991	0.645
LIG_LIR_Nem_3	9	15	PF02991	0.700
LIG_MLH1_MIPbox_1	16	20	PF16413	0.706
LIG_NRBOX	741	747	PF00104	0.804
LIG_PCNA_yPIPBox_3	602	612	PF02747	0.595
LIG_Pex14_1	471	475	PF04695	0.621
LIG_Pex14_2	15	19	PF04695	0.708
LIG_PTB_Apo_2	421	428	PF02174	0.735
LIG_PTB_Phospho_1	421	427	PF10480	0.748
LIG_SH2_CRK	509	513	PF00017	0.599
LIG_SH2_NCK_1	121	125	PF00017	0.715
LIG_SH2_PTP2	475	478	PF00017	0.704
LIG_SH2_STAP1	466	470	PF00017	0.648
LIG_SH2_STAT3	427	430	PF00017	0.769
LIG_SH2_STAT5	121	124	PF00017	0.719
LIG_SH2_STAT5	134	137	PF00017	0.543
LIG_SH2_STAT5	40	43	PF00017	0.721
LIG_SH2_STAT5	466	469	PF00017	0.660
LIG_SH2_STAT5	475	478	PF00017	0.546
LIG_SH3_1	184	190	PF00018	0.848
LIG_SH3_2	260	265	PF14604	0.873
LIG_SH3_2	369	374	PF14604	0.878
LIG_SH3_3	107	113	PF00018	0.700
LIG_SH3_3	130	136	PF00018	0.706
LIG_SH3_3	160	166	PF00018	0.820
LIG_SH3_3	184	190	PF00018	0.848
LIG_SH3_3	206	212	PF00018	0.857
LIG_SH3_3	23	29	PF00018	0.692
LIG_SH3_3	242	248	PF00018	0.878
LIG_SH3_3	257	263	PF00018	0.610
LIG_SH3_3	31	37	PF00018	0.594
LIG_SH3_3	366	372	PF00018	0.874
LIG_SH3_3	398	404	PF00018	0.863
LIG_SH3_3	515	521	PF00018	0.595
LIG_SH3_3	547	553	PF00018	0.687
LIG_SH3_3	86	92	PF00018	0.692
LIG_SUMO_SIM_anti_2	79	84	PF11976	0.697
LIG_SUMO_SIM_par_1	27	33	PF11976	0.702
LIG_SUMO_SIM_par_1	628	634	PF11976	0.826
LIG_TRAF2_1	445	448	PF00917	0.703
LIG_TRFH_1	154	158	PF08558	0.803
LIG_WRC_WIRS_1	12	17	PF05994	0.703
LIG_WW_2	245	248	PF00397	0.866
MOD_CDK_SPK_2	30	35	PF00069	0.709
MOD_CK1_1	119	125	PF00069	0.716
MOD_CK1_1	13	19	PF00069	0.705
MOD_CK1_1	138	144	PF00069	0.458
MOD_CK1_1	168	174	PF00069	0.849
MOD_CK1_1	178	184	PF00069	0.698
MOD_CK1_1	215	221	PF00069	0.860
MOD_CK1_1	229	235	PF00069	0.637
MOD_CK1_1	288	294	PF00069	0.876
MOD_CK1_1	300	306	PF00069	0.670
MOD_CK1_1	307	313	PF00069	0.549
MOD_CK1_1	382	388	PF00069	0.876
MOD_CK1_1	568	574	PF00069	0.808
MOD_CK1_1	59	65	PF00069	0.717
MOD_CK1_1	741	747	PF00069	0.804
MOD_CK2_1	288	294	PF00069	0.876
MOD_CK2_1	303	309	PF00069	0.619
MOD_CK2_1	442	448	PF00069	0.697
MOD_CK2_1	452	458	PF00069	0.473
MOD_CK2_1	541	547	PF00069	0.628
MOD_CK2_1	668	674	PF00069	0.855
MOD_CK2_1	741	747	PF00069	0.804
MOD_Cter_Amidation	181	184	PF01082	0.871
MOD_Cter_Amidation	678	681	PF01082	0.861
MOD_GlcNHglycan	126	129	PF01048	0.703
MOD_GlcNHglycan	149	152	PF01048	0.723
MOD_GlcNHglycan	167	170	PF01048	0.610
MOD_GlcNHglycan	177	180	PF01048	0.697
MOD_GlcNHglycan	200	203	PF01048	0.879
MOD_GlcNHglycan	214	217	PF01048	0.620
MOD_GlcNHglycan	228	231	PF01048	0.638
MOD_GlcNHglycan	287	290	PF01048	0.874
MOD_GlcNHglycan	306	309	PF01048	0.551
MOD_GlcNHglycan	338	341	PF01048	0.878
MOD_GlcNHglycan	344	347	PF01048	0.761
MOD_GlcNHglycan	381	384	PF01048	0.873
MOD_GlcNHglycan	397	400	PF01048	0.587
MOD_GlcNHglycan	410	413	PF01048	0.622
MOD_GlcNHglycan	528	531	PF01048	0.682
MOD_GlcNHglycan	543	546	PF01048	0.372
MOD_GlcNHglycan	620	623	PF01048	0.784
MOD_GlcNHglycan	633	636	PF01048	0.572
MOD_GlcNHglycan	677	680	PF01048	0.862
MOD_GlcNHglycan	691	694	PF01048	0.597
MOD_GlcNHglycan	725	729	PF01048	0.866
MOD_GlcNHglycan	754	757	PF01048	0.854
MOD_GSK3_1	135	142	PF00069	0.711
MOD_GSK3_1	164	171	PF00069	0.842
MOD_GSK3_1	207	214	PF00069	0.858
MOD_GSK3_1	215	222	PF00069	0.719
MOD_GSK3_1	226	233	PF00069	0.548
MOD_GSK3_1	24	31	PF00069	0.458
MOD_GSK3_1	299	306	PF00069	0.880
MOD_GSK3_1	378	385	PF00069	0.875
MOD_GSK3_1	465	472	PF00069	0.640
MOD_GSK3_1	565	572	PF00069	0.804
MOD_GSK3_1	6	13	PF00069	0.695
MOD_GSK3_1	670	677	PF00069	0.859
MOD_GSK3_1	689	696	PF00069	0.507
MOD_GSK3_1	737	744	PF00069	0.823
MOD_GSK3_1	752	759	PF00069	0.592
MOD_N-GLC_1	487	492	PF02516	0.768
MOD_N-GLC_1	541	546	PF02516	0.623
MOD_N-GLC_2	605	607	PF02516	0.591
MOD_NEK2_1	10	15	PF00069	0.702
MOD_NEK2_1	146	151	PF00069	0.714
MOD_NEK2_1	217	222	PF00069	0.856
MOD_NEK2_1	276	281	PF00069	0.859
MOD_NEK2_1	350	355	PF00069	0.867
MOD_NEK2_1	541	546	PF00069	0.623
MOD_NEK2_1	588	593	PF00069	0.747
MOD_NEK2_1	630	635	PF00069	0.819
MOD_NEK2_1	78	83	PF00069	0.700
MOD_NEK2_2	528	533	PF00069	0.672
MOD_NEK2_2	6	11	PF00069	0.693
MOD_PIKK_1	307	313	PF00454	0.882
MOD_PIKK_1	469	475	PF00454	0.623
MOD_PKA_1	283	289	PF00069	0.876
MOD_PKA_2	175	181	PF00069	0.871
MOD_PKA_2	226	232	PF00069	0.881
MOD_PKA_2	283	289	PF00069	0.876
MOD_PKA_2	303	309	PF00069	0.531
MOD_PKA_2	319	325	PF00069	0.607
MOD_PKA_2	336	342	PF00069	0.583
MOD_PKA_2	377	383	PF00069	0.879
MOD_PKA_2	408	414	PF00069	0.857
MOD_PKA_2	419	425	PF00069	0.661
MOD_PKA_2	560	566	PF00069	0.803
MOD_PKA_2	59	65	PF00069	0.717
MOD_PKA_2	625	631	PF00069	0.830
MOD_PKA_2	683	689	PF00069	0.845
MOD_Plk_1	487	493	PF00069	0.767
MOD_Plk_1	737	743	PF00069	0.826
MOD_Plk_2-3	738	744	PF00069	0.820
MOD_Plk_4	101	107	PF00069	0.702
MOD_Plk_4	14	20	PF00069	0.705
MOD_Plk_4	220	226	PF00069	0.855
MOD_Plk_4	35	41	PF00069	0.708
MOD_Plk_4	487	493	PF00069	0.767
MOD_Plk_4	551	557	PF00069	0.762
MOD_Plk_4	625	631	PF00069	0.830
MOD_Plk_4	683	689	PF00069	0.845
MOD_Plk_4	702	708	PF00069	0.446
MOD_Plk_4	741	747	PF00069	0.804
MOD_Plk_4	78	84	PF00069	0.699
MOD_ProDKin_1	159	165	PF00069	0.822
MOD_ProDKin_1	168	174	PF00069	0.691
MOD_ProDKin_1	207	213	PF00069	0.856
MOD_ProDKin_1	22	28	PF00069	0.697
MOD_ProDKin_1	30	36	PF00069	0.596
MOD_ProDKin_1	356	362	PF00069	0.860
MOD_ProDKin_1	513	519	PF00069	0.597
TRG_ENDOCYTIC_2	12	15	PF00928	0.703
TRG_ENDOCYTIC_2	134	137	PF00928	0.714
TRG_ENDOCYTIC_2	509	512	PF00928	0.595
TRG_ER_diArg_1	106	109	PF00400	0.704
TRG_ER_diArg_1	183	185	PF00400	0.874
TRG_ER_diArg_1	272	274	PF00400	0.857
TRG_ER_diArg_1	68	71	PF00400	0.710
TRG_Pf-PMV_PEXEL_1	331	336	PF00026	0.889