CCDC92 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HBX6_LEIBR

TriTrypDb:

LbrM.21.1400 , LBRM2903_210019400

Length:

244

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HBX6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HBX6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	187	191	PF00656	0.490
CLV_C14_Caspase3-7	231	235	PF00656	0.448
CLV_C14_Caspase3-7	62	66	PF00656	0.629
CLV_NRD_NRD_1	116	118	PF00675	0.548
CLV_NRD_NRD_1	177	179	PF00675	0.430
CLV_NRD_NRD_1	232	234	PF00675	0.527
CLV_NRD_NRD_1	98	100	PF00675	0.584
CLV_PCSK_FUR_1	96	100	PF00082	0.554
CLV_PCSK_KEX2_1	116	118	PF00082	0.504
CLV_PCSK_KEX2_1	15	17	PF00082	0.776
CLV_PCSK_KEX2_1	177	179	PF00082	0.430
CLV_PCSK_KEX2_1	232	234	PF00082	0.527
CLV_PCSK_KEX2_1	98	100	PF00082	0.575
CLV_PCSK_PC1ET2_1	15	17	PF00082	0.776
CLV_PCSK_SKI1_1	117	121	PF00082	0.564
CLV_PCSK_SKI1_1	149	153	PF00082	0.347
CLV_PCSK_SKI1_1	177	181	PF00082	0.442
CLV_PCSK_SKI1_1	233	237	PF00082	0.456
DEG_SPOP_SBC_1	42	46	PF00917	0.621
DEG_SPOP_SBC_1	59	63	PF00917	0.612
DOC_CKS1_1	22	27	PF01111	0.553
DOC_CKS1_1	32	37	PF01111	0.509
DOC_CYCLIN_RxL_1	114	122	PF00134	0.498
DOC_MAPK_gen_1	177	184	PF00069	0.512
DOC_MAPK_MEF2A_6	177	184	PF00069	0.512
DOC_USP7_MATH_1	43	47	PF00917	0.618
DOC_USP7_MATH_1	58	62	PF00917	0.623
DOC_USP7_MATH_1	97	101	PF00917	0.701
DOC_USP7_UBL2_3	15	19	PF12436	0.527
DOC_USP7_UBL2_3	9	13	PF12436	0.517
DOC_WW_Pin1_4	21	26	PF00397	0.564
DOC_WW_Pin1_4	239	244	PF00397	0.485
DOC_WW_Pin1_4	31	36	PF00397	0.527
DOC_WW_Pin1_4	64	69	PF00397	0.590
LIG_14-3-3_CanoR_1	96	102	PF00244	0.626
LIG_BIR_II_1	1	5	PF00653	0.501
LIG_FHA_1	12	18	PF00498	0.652
LIG_FHA_1	179	185	PF00498	0.600
LIG_FHA_1	2	8	PF00498	0.644
LIG_FHA_1	208	214	PF00498	0.643
LIG_FHA_1	43	49	PF00498	0.617
LIG_FHA_2	183	189	PF00498	0.472
LIG_MYND_1	38	42	PF01753	0.530
LIG_NRBOX	175	181	PF00104	0.502
LIG_SH2_STAT3	201	204	PF00017	0.519
LIG_SH2_STAT5	160	163	PF00017	0.423
LIG_SH2_STAT5	201	204	PF00017	0.519
LIG_SH3_3	212	218	PF00018	0.592
LIG_SH3_3	32	38	PF00018	0.537
LIG_SH3_3	80	86	PF00018	0.586
LIG_TRAF2_1	185	188	PF00917	0.517
MOD_CDK_SPK_2	34	39	PF00069	0.536
MOD_CK1_1	18	24	PF00069	0.525
MOD_CK1_1	2	8	PF00069	0.629
MOD_CK1_1	28	34	PF00069	0.565
MOD_CK1_1	61	67	PF00069	0.729
MOD_CK1_1	69	75	PF00069	0.651
MOD_CK2_1	182	188	PF00069	0.475
MOD_GlcNHglycan	104	107	PF01048	0.647
MOD_GlcNHglycan	236	239	PF01048	0.468
MOD_GSK3_1	154	161	PF00069	0.530
MOD_GSK3_1	178	185	PF00069	0.514
MOD_GSK3_1	21	28	PF00069	0.648
MOD_GSK3_1	59	66	PF00069	0.734
MOD_GSK3_1	7	14	PF00069	0.586
MOD_GSK3_1	97	104	PF00069	0.636
MOD_NEK2_1	1	6	PF00069	0.567
MOD_NEK2_1	119	124	PF00069	0.542
MOD_NEK2_1	153	158	PF00069	0.466
MOD_NEK2_1	7	12	PF00069	0.577
MOD_NEK2_1	76	81	PF00069	0.526
MOD_PIKK_1	18	24	PF00454	0.546
MOD_PKA_1	15	21	PF00069	0.684
MOD_PKA_2	15	21	PF00069	0.734
MOD_PKA_2	158	164	PF00069	0.422
MOD_PKA_2	97	103	PF00069	0.620
MOD_ProDKin_1	21	27	PF00069	0.566
MOD_ProDKin_1	31	37	PF00069	0.527
MOD_ProDKin_1	64	70	PF00069	0.590
MOD_SUMO_for_1	127	130	PF00179	0.502
TRG_DiLeu_BaEn_1	175	180	PF01217	0.499
TRG_DiLeu_BaLyEn_6	36	41	PF01217	0.536
TRG_DiLeu_LyEn_5	175	180	PF01217	0.499
TRG_ENDOCYTIC_2	137	140	PF00928	0.472
TRG_ENDOCYTIC_2	160	163	PF00928	0.417
TRG_ER_diArg_1	115	117	PF00400	0.504
TRG_ER_diArg_1	176	178	PF00400	0.437
TRG_ER_diArg_1	96	99	PF00400	0.581
TRG_Pf-PMV_PEXEL_1	117	121	PF00026	0.500

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3R7MH71	Trypanosoma rangeli	36%	100%
A0A3S7WWL4	Leishmania donovani	78%	83%
A4HZ96	Leishmania infantum	78%	83%
E9AVA4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	75%	83%
Q4QC76	Leishmania major	76%	100%