Ribosomal protein L10

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Ribosomal protein L1p/L10e family, putative

Species:

Leishmania braziliensis

UniProt:

A4HBX4_LEIBR

TriTrypDb:

LbrM.21.1380 , LBRM2903_210019200

Length:

262

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005730	nucleolus	5	1
GO:0043226	organelle	2	2
GO:0043228	non-membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043232	intracellular non-membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	2
GO:0005840	ribosome	5	1

Expansion

Sequence features

A4HBX4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HBX4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_MEL_PAP_1	204	210	PF00089	0.399
CLV_PCSK_KEX2_1	107	109	PF00082	0.492
CLV_PCSK_KEX2_1	115	117	PF00082	0.447
CLV_PCSK_KEX2_1	5	7	PF00082	0.441
CLV_PCSK_KEX2_1	91	93	PF00082	0.461
CLV_PCSK_PC1ET2_1	107	109	PF00082	0.499
CLV_PCSK_PC1ET2_1	115	117	PF00082	0.436
CLV_PCSK_PC1ET2_1	5	7	PF00082	0.441
CLV_PCSK_PC1ET2_1	91	93	PF00082	0.461
CLV_PCSK_SKI1_1	11	15	PF00082	0.459
CLV_PCSK_SKI1_1	115	119	PF00082	0.482
CLV_PCSK_SKI1_1	169	173	PF00082	0.412
DOC_CKS1_1	170	175	PF01111	0.556
DOC_MAPK_gen_1	249	258	PF00069	0.535
DOC_MAPK_MEF2A_6	252	260	PF00069	0.551
DOC_PP1_RVXF_1	250	256	PF00149	0.528
DOC_PP2B_LxvP_1	76	79	PF13499	0.368
DOC_PP4_FxxP_1	41	44	PF00568	0.391
DOC_PP4_FxxP_1	60	63	PF00568	0.428
DOC_USP7_MATH_1	147	151	PF00917	0.417
DOC_WW_Pin1_4	169	174	PF00397	0.452
LIG_14-3-3_CanoR_1	119	125	PF00244	0.492
LIG_14-3-3_CanoR_1	72	79	PF00244	0.403
LIG_FHA_1	140	146	PF00498	0.561
LIG_FHA_1	190	196	PF00498	0.424
LIG_FHA_1	248	254	PF00498	0.423
LIG_FHA_1	71	77	PF00498	0.399
LIG_FHA_1	8	14	PF00498	0.421
LIG_FHA_2	170	176	PF00498	0.491
LIG_Integrin_isoDGR_2	70	72	PF01839	0.500
LIG_Integrin_RGD_1	108	110	PF01839	0.501
LIG_KLC1_Yacidic_2	35	40	PF13176	0.475
LIG_LIR_Apic_2	40	44	PF02991	0.385
LIG_LIR_Gen_1	123	129	PF02991	0.379
LIG_LIR_Gen_1	35	46	PF02991	0.393
LIG_LIR_Nem_3	123	127	PF02991	0.386
LIG_LIR_Nem_3	232	236	PF02991	0.402
LIG_LIR_Nem_3	242	246	PF02991	0.350
LIG_LIR_Nem_3	35	41	PF02991	0.364
LIG_Pex14_2	233	237	PF04695	0.396
LIG_Pex14_2	41	45	PF04695	0.449
LIG_SH2_CRK	96	100	PF00017	0.416
LIG_SH2_STAP1	96	100	PF00017	0.416
LIG_SH2_STAT3	15	18	PF00017	0.560
LIG_SH2_STAT5	239	242	PF00017	0.446
LIG_SH2_STAT5	38	41	PF00017	0.464
LIG_SH3_3	161	167	PF00018	0.547
LIG_TRAF2_1	32	35	PF00917	0.540
MOD_CK1_1	148	154	PF00069	0.560
MOD_CK1_1	188	194	PF00069	0.495
MOD_CK1_1	244	250	PF00069	0.391
MOD_CK1_1	26	32	PF00069	0.599
MOD_CK2_1	128	134	PF00069	0.286
MOD_GlcNHglycan	150	153	PF01048	0.608
MOD_GlcNHglycan	157	160	PF01048	0.682
MOD_GlcNHglycan	161	164	PF01048	0.641
MOD_GlcNHglycan	28	31	PF01048	0.609
MOD_GSK3_1	141	148	PF00069	0.453
MOD_GSK3_1	155	162	PF00069	0.507
MOD_GSK3_1	181	188	PF00069	0.446
MOD_N-GLC_1	247	252	PF02516	0.525
MOD_NEK2_1	185	190	PF00069	0.457
MOD_NEK2_1	225	230	PF00069	0.433
MOD_NEK2_1	45	50	PF00069	0.443
MOD_NEK2_1	7	12	PF00069	0.409
MOD_PIKK_1	185	191	PF00454	0.456
MOD_PIKK_1	46	52	PF00454	0.431
MOD_PKA_2	179	185	PF00069	0.475
MOD_PKA_2	26	32	PF00069	0.579
MOD_PKA_2	71	77	PF00069	0.418
MOD_Plk_1	241	247	PF00069	0.494
MOD_Plk_4	232	238	PF00069	0.411
MOD_ProDKin_1	169	175	PF00069	0.457
MOD_SUMO_for_1	229	232	PF00179	0.451
MOD_SUMO_rev_2	130	138	PF00179	0.314
TRG_DiLeu_BaEn_2	250	256	PF01217	0.435
TRG_DiLeu_BaLyEn_6	3	8	PF01217	0.457
TRG_ENDOCYTIC_2	38	41	PF00928	0.436
TRG_ENDOCYTIC_2	96	99	PF00928	0.418
TRG_ER_diArg_1	252	255	PF00400	0.531

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HUF4	Leptomonas seymouri	77%	99%
A0A0S4JGP8	Bodo saltans	49%	100%
A0A1X0NYA3	Trypanosomatidae	52%	87%
A0A3Q8IC01	Leishmania donovani	86%	99%
A0A3R7N930	Trypanosoma rangeli	54%	90%
A4HZ94	Leishmania infantum	85%	99%
D0A178	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	51%	88%
E9AVA2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	98%
Q4QC78	Leishmania major	85%	100%