Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HBV6_LEIBR

TriTrypDb:

LbrM.21.1190 , LBRM2903_210016500

Length:

914

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HBV6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HBV6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	294	298	PF00656	0.837
CLV_C14_Caspase3-7	336	340	PF00656	0.852
CLV_C14_Caspase3-7	449	453	PF00656	0.822
CLV_C14_Caspase3-7	608	612	PF00656	0.842
CLV_C14_Caspase3-7	861	865	PF00656	0.858
CLV_NRD_NRD_1	149	151	PF00675	0.862
CLV_NRD_NRD_1	152	154	PF00675	0.806
CLV_NRD_NRD_1	234	236	PF00675	0.805
CLV_NRD_NRD_1	278	280	PF00675	0.824
CLV_NRD_NRD_1	316	318	PF00675	0.847
CLV_NRD_NRD_1	320	322	PF00675	0.801
CLV_NRD_NRD_1	355	357	PF00675	0.860
CLV_NRD_NRD_1	394	396	PF00675	0.749
CLV_NRD_NRD_1	401	403	PF00675	0.644
CLV_NRD_NRD_1	563	565	PF00675	0.790
CLV_NRD_NRD_1	572	574	PF00675	0.663
CLV_NRD_NRD_1	774	776	PF00675	0.876
CLV_NRD_NRD_1	825	827	PF00675	0.862
CLV_NRD_NRD_1	830	832	PF00675	0.771
CLV_NRD_NRD_1	886	888	PF00675	0.777
CLV_NRD_NRD_1	907	909	PF00675	0.890
CLV_PCSK_FUR_1	150	154	PF00082	0.858
CLV_PCSK_FUR_1	313	317	PF00082	0.838
CLV_PCSK_KEX2_1	148	150	PF00082	0.860
CLV_PCSK_KEX2_1	152	154	PF00082	0.789
CLV_PCSK_KEX2_1	234	236	PF00082	0.805
CLV_PCSK_KEX2_1	278	280	PF00082	0.824
CLV_PCSK_KEX2_1	315	317	PF00082	0.843
CLV_PCSK_KEX2_1	322	324	PF00082	0.746
CLV_PCSK_KEX2_1	355	357	PF00082	0.860
CLV_PCSK_KEX2_1	394	396	PF00082	0.749
CLV_PCSK_KEX2_1	401	403	PF00082	0.644
CLV_PCSK_KEX2_1	572	574	PF00082	0.821
CLV_PCSK_KEX2_1	774	776	PF00082	0.876
CLV_PCSK_KEX2_1	825	827	PF00082	0.862
CLV_PCSK_KEX2_1	886	888	PF00082	0.777
CLV_PCSK_PC1ET2_1	148	150	PF00082	0.860
CLV_PCSK_PC1ET2_1	322	324	PF00082	0.868
CLV_PCSK_PC7_1	390	396	PF00082	0.742
CLV_PCSK_SKI1_1	126	130	PF00082	0.733
CLV_PCSK_SKI1_1	13	17	PF00082	0.658
CLV_PCSK_SKI1_1	205	209	PF00082	0.629
CLV_PCSK_SKI1_1	316	320	PF00082	0.855
CLV_PCSK_SKI1_1	62	66	PF00082	0.675
CLV_PCSK_SKI1_1	656	660	PF00082	0.843
CLV_PCSK_SKI1_1	722	726	PF00082	0.824
CLV_PCSK_SKI1_1	783	787	PF00082	0.883
CLV_PCSK_SKI1_1	88	92	PF00082	0.653
DEG_APCC_DBOX_1	204	212	PF00400	0.627
DEG_COP1_1	723	732	PF00400	0.817
DEG_Nend_Nbox_1	1	3	PF02207	0.843
DEG_SPOP_SBC_1	737	741	PF00917	0.821
DEG_SPOP_SBC_1	812	816	PF00917	0.864
DOC_CKS1_1	20	25	PF01111	0.675
DOC_CYCLIN_RxL_1	422	433	PF00134	0.815
DOC_CYCLIN_RxL_1	886	898	PF00134	0.793
DOC_CYCLIN_yCln2_LP_2	20	26	PF00134	0.678
DOC_MAPK_gen_1	355	363	PF00069	0.856
DOC_MAPK_gen_1	401	407	PF00069	0.775
DOC_MAPK_gen_1	886	894	PF00069	0.780
DOC_MAPK_HePTP_8	375	387	PF00069	0.764
DOC_MAPK_MEF2A_6	378	387	PF00069	0.756
DOC_PP1_RVXF_1	423	430	PF00149	0.829
DOC_PP2B_LxvP_1	129	132	PF13499	0.764
DOC_PP4_FxxP_1	727	730	PF00568	0.813
DOC_USP7_MATH_1	140	144	PF00917	0.843
DOC_USP7_MATH_1	162	166	PF00917	0.801
DOC_USP7_MATH_1	245	249	PF00917	0.850
DOC_USP7_MATH_1	25	29	PF00917	0.686
DOC_USP7_MATH_1	255	259	PF00917	0.657
DOC_USP7_MATH_1	502	506	PF00917	0.842
DOC_USP7_MATH_1	582	586	PF00917	0.834
DOC_USP7_MATH_1	698	702	PF00917	0.853
DOC_USP7_MATH_1	737	741	PF00917	0.821
DOC_USP7_MATH_1	776	780	PF00917	0.876
DOC_USP7_MATH_2	183	189	PF00917	0.624
DOC_USP7_UBL2_3	652	656	PF12436	0.841
DOC_WW_Pin1_4	19	24	PF00397	0.672
DOC_WW_Pin1_4	489	494	PF00397	0.884
DOC_WW_Pin1_4	871	876	PF00397	0.878
DOC_WW_Pin1_4	96	101	PF00397	0.752
LIG_14-3-3_CanoR_1	150	159	PF00244	0.852
LIG_14-3-3_CanoR_1	32	40	PF00244	0.638
LIG_14-3-3_CanoR_1	355	363	PF00244	0.856
LIG_14-3-3_CanoR_1	401	406	PF00244	0.771
LIG_14-3-3_CanoR_1	500	510	PF00244	0.841
LIG_14-3-3_CanoR_1	521	526	PF00244	0.826
LIG_14-3-3_CanoR_1	587	595	PF00244	0.841
LIG_14-3-3_CanoR_1	673	682	PF00244	0.820
LIG_14-3-3_CanoR_1	697	703	PF00244	0.857
LIG_14-3-3_CanoR_1	829	838	PF00244	0.861
LIG_Actin_WH2_2	423	438	PF00022	0.806
LIG_Actin_WH2_2	78	93	PF00022	0.644
LIG_APCC_ABBA_1	873	878	PF00400	0.873
LIG_BRCT_BRCA1_1	101	105	PF00533	0.832
LIG_BRCT_BRCA1_1	720	724	PF00533	0.819
LIG_Clathr_ClatBox_1	181	185	PF01394	0.617
LIG_CtBP_PxDLS_1	183	187	PF00389	0.628
LIG_deltaCOP1_diTrp_1	297	306	PF00928	0.837
LIG_FHA_1	131	137	PF00498	0.797
LIG_FHA_1	156	162	PF00498	0.831
LIG_FHA_1	28	34	PF00498	0.651
LIG_FHA_1	327	333	PF00498	0.859
LIG_FHA_1	402	408	PF00498	0.780
LIG_FHA_1	601	607	PF00498	0.833
LIG_FHA_1	96	102	PF00498	0.763
LIG_FHA_2	334	340	PF00498	0.854
LIG_FHA_2	36	42	PF00498	0.649
LIG_FHA_2	723	729	PF00498	0.822
LIG_FHA_2	859	865	PF00498	0.859
LIG_GBD_Chelix_1	60	68	PF00786	0.665
LIG_IBAR_NPY_1	684	686	PF08397	0.814
LIG_Integrin_isoDGR_2	906	908	PF01839	0.888
LIG_Integrin_RGD_1	94	96	PF01839	0.679
LIG_LIR_Apic_2	679	685	PF02991	0.809
LIG_LIR_Apic_2	725	730	PF02991	0.817
LIG_LIR_Gen_1	34	43	PF02991	0.647
LIG_LIR_Gen_1	411	418	PF02991	0.833
LIG_LIR_Gen_1	721	732	PF02991	0.818
LIG_LIR_Gen_1	80	90	PF02991	0.638
LIG_LIR_Nem_3	165	171	PF02991	0.722
LIG_LIR_Nem_3	34	39	PF02991	0.641
LIG_LIR_Nem_3	411	416	PF02991	0.836
LIG_LIR_Nem_3	721	727	PF02991	0.822
LIG_LIR_Nem_3	80	85	PF02991	0.642
LIG_MYND_1	871	875	PF01753	0.877
LIG_NRP_CendR_1	911	914	PF00754	0.893
LIG_Pex14_1	682	686	PF04695	0.819
LIG_SH2_CRK	889	893	PF00017	0.778
LIG_SH2_STAP1	410	414	PF00017	0.834
LIG_SH2_STAP1	884	888	PF00017	0.784
LIG_SH2_STAT3	374	377	PF00017	0.800
LIG_SH2_STAT3	712	715	PF00017	0.850
LIG_SH2_STAT5	127	130	PF00017	0.728
LIG_SH2_STAT5	197	200	PF00017	0.607
LIG_SH2_STAT5	225	228	PF00017	0.757
LIG_SH2_STAT5	374	377	PF00017	0.800
LIG_SH2_STAT5	595	598	PF00017	0.840
LIG_SH2_STAT5	686	689	PF00017	0.837
LIG_SH2_STAT5	712	715	PF00017	0.850
LIG_SH3_1	490	496	PF00018	0.871
LIG_SH3_1	543	549	PF00018	0.853
LIG_SH3_1	626	632	PF00018	0.875
LIG_SH3_2	769	774	PF14604	0.851
LIG_SH3_3	119	125	PF00018	0.746
LIG_SH3_3	341	347	PF00018	0.853
LIG_SH3_3	420	426	PF00018	0.827
LIG_SH3_3	49	55	PF00018	0.709
LIG_SH3_3	490	496	PF00018	0.871
LIG_SH3_3	543	549	PF00018	0.853
LIG_SH3_3	626	632	PF00018	0.875
LIG_SH3_3	731	737	PF00018	0.811
LIG_SH3_3	753	759	PF00018	0.834
LIG_SH3_3	763	769	PF00018	0.670
LIG_SH3_3	817	823	PF00018	0.863
LIG_SH3_3	869	875	PF00018	0.877
LIG_SH3_CIN85_PxpxPR_1	559	564	PF14604	0.800
LIG_SUMO_SIM_anti_2	384	389	PF11976	0.727
LIG_SUMO_SIM_par_1	127	134	PF11976	0.761
LIG_SUMO_SIM_par_1	157	163	PF11976	0.823
LIG_SUMO_SIM_par_1	265	271	PF11976	0.829
LIG_TRAF2_1	431	434	PF00917	0.777
LIG_TRAF2_1	465	468	PF00917	0.829
LIG_TRAF2_2	766	771	PF00917	0.846
LIG_WRC_WIRS_1	226	231	PF05994	0.766
LIG_WRC_WIRS_1	79	84	PF05994	0.649
LIG_WW_3	544	548	PF00397	0.851
MOD_CK1_1	154	160	PF00069	0.842
MOD_CK1_1	258	264	PF00069	0.837
MOD_CK1_1	271	277	PF00069	0.590
MOD_CK1_1	291	297	PF00069	0.488
MOD_CK1_1	308	314	PF00069	0.538
MOD_CK1_1	364	370	PF00069	0.830
MOD_CK1_1	489	495	PF00069	0.876
MOD_CK1_1	524	530	PF00069	0.824
MOD_CK1_1	532	538	PF00069	0.704
MOD_CK1_1	575	581	PF00069	0.818
MOD_CK1_1	654	660	PF00069	0.840
MOD_CK1_1	676	682	PF00069	0.815
MOD_CK1_1	701	707	PF00069	0.848
MOD_CK1_1	779	785	PF00069	0.881
MOD_CK1_1	858	864	PF00069	0.858
MOD_CK1_1	865	871	PF00069	0.751
MOD_CK1_1	99	105	PF00069	0.821
MOD_CK2_1	428	434	PF00069	0.797
MOD_CK2_1	879	885	PF00069	0.811
MOD_Cter_Amidation	150	153	PF01082	0.863
MOD_Cter_Amidation	906	909	PF01082	0.888
MOD_GlcNHglycan	101	104	PF01048	0.829
MOD_GlcNHglycan	133	136	PF01048	0.798
MOD_GlcNHglycan	164	167	PF01048	0.798
MOD_GlcNHglycan	242	245	PF01048	0.833
MOD_GlcNHglycan	27	30	PF01048	0.681
MOD_GlcNHglycan	270	273	PF01048	0.822
MOD_GlcNHglycan	281	284	PF01048	0.635
MOD_GlcNHglycan	290	293	PF01048	0.487
MOD_GlcNHglycan	307	310	PF01048	0.543
MOD_GlcNHglycan	363	366	PF01048	0.841
MOD_GlcNHglycan	512	515	PF01048	0.834
MOD_GlcNHglycan	517	520	PF01048	0.742
MOD_GlcNHglycan	531	534	PF01048	0.499
MOD_GlcNHglycan	554	557	PF01048	0.831
MOD_GlcNHglycan	611	614	PF01048	0.854
MOD_GlcNHglycan	633	636	PF01048	0.860
MOD_GlcNHglycan	679	682	PF01048	0.812
MOD_GlcNHglycan	740	743	PF01048	0.830
MOD_GlcNHglycan	777	781	PF01048	0.880
MOD_GlcNHglycan	864	867	PF01048	0.865
MOD_GSK3_1	104	111	PF00069	0.672
MOD_GSK3_1	151	158	PF00069	0.852
MOD_GSK3_1	234	241	PF00069	0.805
MOD_GSK3_1	245	252	PF00069	0.657
MOD_GSK3_1	258	265	PF00069	0.608
MOD_GSK3_1	27	34	PF00069	0.661
MOD_GSK3_1	324	331	PF00069	0.861
MOD_GSK3_1	359	366	PF00069	0.848
MOD_GSK3_1	444	451	PF00069	0.840
MOD_GSK3_1	502	509	PF00069	0.835
MOD_GSK3_1	517	524	PF00069	0.566
MOD_GSK3_1	525	532	PF00069	0.684
MOD_GSK3_1	601	608	PF00069	0.833
MOD_GSK3_1	617	624	PF00069	0.591
MOD_GSK3_1	627	634	PF00069	0.692
MOD_GSK3_1	673	680	PF00069	0.821
MOD_GSK3_1	697	704	PF00069	0.854
MOD_GSK3_1	714	721	PF00069	0.531
MOD_GSK3_1	779	786	PF00069	0.880
MOD_GSK3_1	832	839	PF00069	0.860
MOD_GSK3_1	858	865	PF00069	0.858
MOD_GSK3_1	95	102	PF00069	0.754
MOD_N-GLC_1	327	332	PF02516	0.861
MOD_N-GLC_1	654	659	PF02516	0.839
MOD_N-GLC_2	669	671	PF02516	0.840
MOD_NEK2_1	184	189	PF00069	0.625
MOD_NEK2_1	249	254	PF00069	0.848
MOD_NEK2_1	268	273	PF00069	0.491
MOD_NEK2_1	396	401	PF00069	0.747
MOD_NEK2_1	435	440	PF00069	0.801
MOD_NEK2_1	473	478	PF00069	0.864
MOD_NEK2_1	512	517	PF00069	0.836
MOD_NEK2_1	531	536	PF00069	0.503
MOD_NEK2_1	552	557	PF00069	0.837
MOD_NEK2_1	738	743	PF00069	0.829
MOD_NEK2_1	77	82	PF00069	0.640
MOD_NEK2_1	830	835	PF00069	0.857
MOD_NEK2_2	11	16	PF00069	0.640
MOD_NEK2_2	27	32	PF00069	0.383
MOD_NEK2_2	582	587	PF00069	0.837
MOD_NEK2_2	879	884	PF00069	0.817
MOD_OFUCOSY	671	677	PF10250	0.831
MOD_PIKK_1	152	158	PF00454	0.852
MOD_PIKK_1	234	240	PF00454	0.806
MOD_PIKK_1	428	434	PF00454	0.797
MOD_PK_1	521	527	PF00069	0.827
MOD_PKA_1	152	158	PF00069	0.852
MOD_PKA_1	234	240	PF00069	0.806
MOD_PKA_1	401	407	PF00069	0.775
MOD_PKA_1	572	578	PF00069	0.819
MOD_PKA_1	825	831	PF00069	0.860
MOD_PKA_2	151	157	PF00069	0.854
MOD_PKA_2	234	240	PF00069	0.806
MOD_PKA_2	31	37	PF00069	0.635
MOD_PKA_2	348	354	PF00069	0.851
MOD_PKA_2	401	407	PF00069	0.775
MOD_PKA_2	515	521	PF00069	0.834
MOD_PKA_2	552	558	PF00069	0.834
MOD_PKA_2	572	578	PF00069	0.469
MOD_PKA_2	622	628	PF00069	0.886
MOD_PKA_2	696	702	PF00069	0.856
MOD_PKA_2	825	831	PF00069	0.860
MOD_PKB_1	150	158	PF00069	0.853
MOD_PKB_1	673	681	PF00069	0.818
MOD_PKB_1	829	837	PF00069	0.860
MOD_Plk_1	184	190	PF00069	0.619
MOD_Plk_1	327	333	PF00069	0.859
MOD_Plk_1	359	365	PF00069	0.851
MOD_Plk_1	381	387	PF00069	0.747
MOD_Plk_1	466	472	PF00069	0.843
MOD_Plk_1	601	607	PF00069	0.833
MOD_Plk_1	654	660	PF00069	0.840
MOD_Plk_1	722	728	PF00069	0.825
MOD_Plk_2-3	35	41	PF00069	0.639
MOD_Plk_4	245	251	PF00069	0.851
MOD_Plk_4	35	41	PF00069	0.639
MOD_Plk_4	383	389	PF00069	0.733
MOD_Plk_4	466	472	PF00069	0.843
MOD_Plk_4	502	508	PF00069	0.837
MOD_Plk_4	525	531	PF00069	0.824
MOD_Plk_4	547	553	PF00069	0.846
MOD_Plk_4	654	660	PF00069	0.840
MOD_Plk_4	698	704	PF00069	0.852
MOD_Plk_4	728	734	PF00069	0.814
MOD_ProDKin_1	19	25	PF00069	0.666
MOD_ProDKin_1	489	495	PF00069	0.876
MOD_ProDKin_1	871	877	PF00069	0.876
MOD_ProDKin_1	96	102	PF00069	0.763
MOD_SUMO_for_1	802	805	PF00179	0.871
MOD_SUMO_rev_2	364	372	PF00179	0.826
MOD_SUMO_rev_2	431	438	PF00179	0.782
MOD_SUMO_rev_2	644	654	PF00179	0.840
TRG_DiLeu_BaLyEn_6	756	761	PF01217	0.837
TRG_ENDOCYTIC_2	410	413	PF00928	0.832
TRG_ENDOCYTIC_2	889	892	PF00928	0.777
TRG_ER_diArg_1	149	152	PF00400	0.864
TRG_ER_diArg_1	313	316	PF00400	0.835
TRG_ER_diArg_1	320	323	PF00400	0.749
TRG_ER_diArg_1	355	357	PF00400	0.860
TRG_ER_diArg_1	394	396	PF00400	0.749
TRG_ER_diArg_1	400	402	PF00400	0.653
TRG_ER_diArg_1	571	573	PF00400	0.807
TRG_ER_diArg_1	824	826	PF00400	0.865
TRG_ER_diArg_1	886	888	PF00400	0.777
TRG_ER_diLys_1	909	914	PF00400	0.890
TRG_NLS_MonoExtC_3	147	152	PF00514	0.862
TRG_NLS_MonoExtC_3	907	913	PF00514	0.887
TRG_NLS_MonoExtN_4	145	152	PF00514	0.860
TRG_NLS_MonoExtN_4	319	325	PF00514	0.868
TRG_Pf-PMV_PEXEL_1	13	17	PF00026	0.658
TRG_Pf-PMV_PEXEL_1	355	360	PF00026	0.860
TRG_Pf-PMV_PEXEL_1	378	382	PF00026	0.773
TRG_Pf-PMV_PEXEL_1	394	398	PF00026	0.467
TRG_Pf-PMV_PEXEL_1	836	840	PF00026	0.865
TRG_Pf-PMV_PEXEL_1	860	864	PF00026	0.859
TRG_Pf-PMV_PEXEL_1	88	92	PF00026	0.653
TRG_Pf-PMV_PEXEL_1	886	891	PF00026	0.778