DUF4220 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HBU6_LEIBR

TriTrypDb:

LbrM.21.1090 , LBRM2903_210015800

Length:

108


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Could not find GO cellular_component term for this entry.

A4HBU6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HBU6


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	45	47	PF00675	0.501
DOC_MAPK_gen_1	18	25	PF00069	0.550
DOC_USP7_MATH_1	100	104	PF00917	0.462
LIG_14-3-3_CanoR_1	46	54	PF00244	0.567
LIG_14-3-3_CanoR_1	6	16	PF00244	0.538
LIG_Actin_WH2_2	19	36	PF00022	0.549
LIG_BIR_II_1	1	5	PF00653	0.672
LIG_BIR_III_4	71	75	PF00653	0.577
LIG_FHA_1	20	26	PF00498	0.617
LIG_SH2_NCK_1	37	41	PF00017	0.694
MOD_CK1_1	2	8	PF00069	0.663
MOD_CK2_1	39	45	PF00069	0.641
MOD_GlcNHglycan	1	4	PF01048	0.513
MOD_GlcNHglycan	93	96	PF01048	0.700
MOD_GSK3_1	86	93	PF00069	0.387
MOD_N-GLC_1	90	95	PF02516	0.659
MOD_NEK2_1	50	55	PF00069	0.475
MOD_PKA_2	45	51	PF00069	0.577
MOD_Plk_1	50	56	PF00069	0.475
MOD_Plk_2-3	45	51	PF00069	0.577
MOD_Plk_4	50	56	PF00069	0.494
MOD_Plk_4	61	67	PF00069	0.369
MOD_SUMO_rev_2	42	48	PF00179	0.583


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IA12	Leptomonas seymouri	65%	100%
A0A3S7WWH6	Leishmania donovani	84%	100%
E9AGV2	Leishmania infantum	84%	100%
E9AV68	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	100%
Q4QCB3	Leishmania major	83%	100%