t-SNARE coiled-coil homology domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Qc-SNARE protein, putative

Species:

Leishmania braziliensis

UniProt:

A4HBQ3_LEIBR

TriTrypDb:

LbrM.21.0620 , LBRM2903_210010800

Length:

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	9
GO:0110165	cellular anatomical entity	1	9

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Expansion

Sequence features

A4HBQ3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HBQ3

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	62	64	PF00675	0.418
CLV_PCSK_KEX2_1	62	64	PF00082	0.401
DOC_MAPK_MEF2A_6	78	87	PF00069	0.400
DOC_USP7_MATH_1	2	6	PF00917	0.548
DOC_USP7_MATH_1	58	62	PF00917	0.637
LIG_BIR_II_1	1	5	PF00653	0.576
LIG_BRCT_BRCA1_1	76	80	PF00533	0.476
LIG_EH1_1	80	88	PF00400	0.443
LIG_eIF4E_1	81	87	PF01652	0.487
LIG_FHA_2	55	61	PF00498	0.656

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PFZ7	Leptomonas seymouri	79%	100%
A0A0S4JF09	Bodo saltans	59%	94%
A0A1X0NXH2	Trypanosomatidae	61%	92%
A0A3S7WWG9	Leishmania donovani	89%	100%
A4HZ55	Leishmania infantum	89%	100%
D0A1Q5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	52%	100%
E9AV23	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
Q4QCF9	Leishmania major	87%	100%

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