Mitochondrial dynamics protein MID51

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HBG5_LEIBR

TriTrypDb:

LbrM.20.4050 , LBRM2903_200054900

Length:

358

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HBG5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HBG5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	24	26	PF00675	0.683
CLV_NRD_NRD_1	50	52	PF00675	0.739
CLV_PCSK_KEX2_1	24	26	PF00082	0.683
CLV_PCSK_KEX2_1	242	244	PF00082	0.701
CLV_PCSK_KEX2_1	52	54	PF00082	0.763
CLV_PCSK_PC1ET2_1	242	244	PF00082	0.701
CLV_PCSK_PC1ET2_1	52	54	PF00082	0.784
CLV_PCSK_SKI1_1	189	193	PF00082	0.556
CLV_PCSK_SKI1_1	334	338	PF00082	0.495
CLV_PCSK_SKI1_1	40	44	PF00082	0.651
CLV_PCSK_SKI1_1	96	100	PF00082	0.532
DEG_APCC_DBOX_1	39	47	PF00400	0.626
DOC_CKS1_1	121	126	PF01111	0.385
DOC_CYCLIN_RxL_1	331	339	PF00134	0.519
DOC_MAPK_DCC_7	232	241	PF00069	0.737
DOC_MAPK_DCC_7	242	250	PF00069	0.521
DOC_MAPK_gen_1	242	250	PF00069	0.658
DOC_PP1_RVXF_1	154	161	PF00149	0.410
DOC_PP2B_LxvP_1	46	49	PF13499	0.578
DOC_PP4_FxxP_1	273	276	PF00568	0.489
DOC_USP7_UBL2_3	92	96	PF12436	0.388
DOC_WW_Pin1_4	120	125	PF00397	0.525
DOC_WW_Pin1_4	173	178	PF00397	0.571
DOC_WW_Pin1_4	209	214	PF00397	0.708
DOC_WW_Pin1_4	226	231	PF00397	0.447
DOC_WW_Pin1_4	234	239	PF00397	0.704
DOC_WW_Pin1_4	320	325	PF00397	0.482
LIG_14-3-3_CanoR_1	139	144	PF00244	0.433
LIG_14-3-3_CanoR_1	185	189	PF00244	0.528
LIG_14-3-3_CanoR_1	24	28	PF00244	0.451
LIG_14-3-3_CanoR_1	53	59	PF00244	0.662
LIG_14-3-3_CanoR_1	75	83	PF00244	0.586
LIG_Actin_WH2_2	26	42	PF00022	0.445
LIG_Actin_WH2_2	306	321	PF00022	0.620
LIG_BIR_II_1	1	5	PF00653	0.727
LIG_deltaCOP1_diTrp_1	105	114	PF00928	0.346
LIG_DLG_GKlike_1	139	147	PF00625	0.380
LIG_EH1_1	30	38	PF00400	0.436
LIG_eIF4E_1	31	37	PF01652	0.586
LIG_FHA_1	231	237	PF00498	0.728
LIG_FHA_1	24	30	PF00498	0.692
LIG_FHA_1	304	310	PF00498	0.422
LIG_FHA_1	55	61	PF00498	0.666
LIG_FHA_1	78	84	PF00498	0.583
LIG_FHA_2	121	127	PF00498	0.530
LIG_LIR_Apic_2	272	276	PF02991	0.489
LIG_LIR_Gen_1	105	114	PF02991	0.451
LIG_LIR_Gen_1	123	131	PF02991	0.602
LIG_LIR_Gen_1	217	225	PF02991	0.611
LIG_LIR_Nem_3	105	110	PF02991	0.480
LIG_LIR_Nem_3	123	128	PF02991	0.572
LIG_LIR_Nem_3	159	163	PF02991	0.519
LIG_LIR_Nem_3	217	221	PF02991	0.615
LIG_NRBOX	201	207	PF00104	0.590
LIG_NRBOX	263	269	PF00104	0.640
LIG_NRBOX	313	319	PF00104	0.360
LIG_PAM2_1	219	231	PF00658	0.467
LIG_PTB_Apo_2	267	274	PF02174	0.466
LIG_SH2_CRK	290	294	PF00017	0.502
LIG_SH2_SRC	347	350	PF00017	0.589
LIG_SH2_STAT5	152	155	PF00017	0.643
LIG_SH2_STAT5	240	243	PF00017	0.616
LIG_SH2_STAT5	7	10	PF00017	0.528
LIG_SH3_3	118	124	PF00018	0.369
LIG_SUMO_SIM_par_1	200	207	PF11976	0.438
LIG_SUMO_SIM_par_1	25	30	PF11976	0.652
LIG_SUMO_SIM_par_1	305	311	PF11976	0.434
MOD_CDK_SPxK_1	226	232	PF00069	0.502
MOD_CDK_SPxxK_3	209	216	PF00069	0.715
MOD_CK1_1	2	8	PF00069	0.641
MOD_CK1_1	323	329	PF00069	0.420
MOD_CK2_1	120	126	PF00069	0.530
MOD_CK2_1	139	145	PF00069	0.503
MOD_CK2_1	201	207	PF00069	0.439
MOD_GlcNHglycan	1	4	PF01048	0.618
MOD_GlcNHglycan	209	212	PF01048	0.460
MOD_GlcNHglycan	338	341	PF01048	0.407
MOD_GlcNHglycan	8	11	PF01048	0.598
MOD_GSK3_1	135	142	PF00069	0.407
MOD_GSK3_1	197	204	PF00069	0.678
MOD_GSK3_1	2	9	PF00069	0.602
MOD_GSK3_1	226	233	PF00069	0.734
MOD_N-GLC_1	207	212	PF02516	0.543
MOD_N-GLC_1	269	274	PF02516	0.726
MOD_NEK2_1	163	168	PF00069	0.331
MOD_NEK2_1	23	28	PF00069	0.492
MOD_NEK2_1	271	276	PF00069	0.717
MOD_NEK2_1	298	303	PF00069	0.625
MOD_NEK2_1	318	323	PF00069	0.339
MOD_NEK2_1	336	341	PF00069	0.369
MOD_NEK2_2	184	189	PF00069	0.409
MOD_OGLYCOS	136	141	PF02709	0.381
MOD_PIKK_1	197	203	PF00454	0.526
MOD_PKA_1	54	60	PF00069	0.750
MOD_PKA_2	184	190	PF00069	0.526
MOD_PKA_2	23	29	PF00069	0.520
MOD_PKA_2	318	324	PF00069	0.666
MOD_PKA_2	54	60	PF00069	0.704
MOD_PKA_2	76	82	PF00069	0.650
MOD_PKB_1	75	83	PF00069	0.606
MOD_Plk_1	269	275	PF00069	0.728
MOD_Plk_4	163	169	PF00069	0.338
MOD_Plk_4	201	207	PF00069	0.691
MOD_Plk_4	32	38	PF00069	0.698
MOD_ProDKin_1	120	126	PF00069	0.530
MOD_ProDKin_1	173	179	PF00069	0.573
MOD_ProDKin_1	209	215	PF00069	0.709
MOD_ProDKin_1	226	232	PF00069	0.451
MOD_ProDKin_1	234	240	PF00069	0.704
MOD_ProDKin_1	320	326	PF00069	0.481
MOD_SUMO_for_1	241	244	PF00179	0.704
TRG_DiLeu_BaEn_1	32	37	PF01217	0.684
TRG_DiLeu_BaLyEn_6	341	346	PF01217	0.486
TRG_ENDOCYTIC_2	125	128	PF00928	0.521
TRG_ENDOCYTIC_2	131	134	PF00928	0.482
TRG_ENDOCYTIC_2	261	264	PF00928	0.569
TRG_ENDOCYTIC_2	290	293	PF00928	0.502
TRG_ER_diArg_1	23	25	PF00400	0.681
TRG_ER_diArg_1	75	78	PF00400	0.634
TRG_NES_CRM1_1	32	47	PF08389	0.495
TRG_NLS_MonoCore_2	50	55	PF00514	0.741
TRG_NLS_MonoExtC_3	50	55	PF00514	0.678
TRG_NLS_MonoExtN_4	49	56	PF00514	0.780
TRG_Pf-PMV_PEXEL_1	25	30	PF00026	0.685
TRG_Pf-PMV_PEXEL_1	344	348	PF00026	0.452

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HRX1	Leptomonas seymouri	43%	100%
A0A3Q8ILM5	Leishmania donovani	76%	100%
A4IAL1	Leishmania infantum	77%	100%
E9B5N6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	76%	100%
Q4Q282	Leishmania major	75%	100%