Separase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Separase

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HBD4_LEIBR

TriTrypDb:

LbrM.20.3740 , LBRM2903_200051700

Length:

2067

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0005929	cilium	4	1
GO:0042995	cell projection	2	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0110165	cellular anatomical entity	1	1
GO:0120025	plasma membrane bounded cell projection	3	1

Expansion

Sequence features

A4HBD4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term	Name	Level	Count
GO:0000226	microtubule cytoskeleton organization	3	3
GO:0001578	microtubule bundle formation	4	3
GO:0003341	cilium movement	4	3
GO:0006996	organelle organization	4	3
GO:0007010	cytoskeleton organization	5	3
GO:0007017	microtubule-based process	2	3
GO:0007018	microtubule-based movement	3	3
GO:0009987	cellular process	1	3
GO:0016043	cellular component organization	3	3
GO:0022607	cellular component assembly	4	3
GO:0035082	axoneme assembly	5	3
GO:0060294	cilium movement involved in cell motility	5	3
GO:0071840	cellular component organization or biogenesis	2	3

Could not find GO molecular_function term for this entry.

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	152	156	PF00656	0.581
CLV_C14_Caspase3-7	1610	1614	PF00656	0.506
CLV_C14_Caspase3-7	2017	2021	PF00656	0.253
CLV_C14_Caspase3-7	584	588	PF00656	0.519
CLV_C14_Caspase3-7	963	967	PF00656	0.234
CLV_NRD_NRD_1	1215	1217	PF00675	0.527
CLV_NRD_NRD_1	1605	1607	PF00675	0.393
CLV_NRD_NRD_1	1721	1723	PF00675	0.512
CLV_NRD_NRD_1	1741	1743	PF00675	0.334
CLV_NRD_NRD_1	193	195	PF00675	0.537
CLV_NRD_NRD_1	2024	2026	PF00675	0.475
CLV_NRD_NRD_1	386	388	PF00675	0.451
CLV_NRD_NRD_1	714	716	PF00675	0.604
CLV_NRD_NRD_1	774	776	PF00675	0.454
CLV_NRD_NRD_1	794	796	PF00675	0.280
CLV_NRD_NRD_1	857	859	PF00675	0.443
CLV_PCSK_KEX2_1	1017	1019	PF00082	0.580
CLV_PCSK_KEX2_1	1023	1025	PF00082	0.464
CLV_PCSK_KEX2_1	1215	1217	PF00082	0.527
CLV_PCSK_KEX2_1	1605	1607	PF00082	0.393
CLV_PCSK_KEX2_1	1720	1722	PF00082	0.513
CLV_PCSK_KEX2_1	1844	1846	PF00082	0.586
CLV_PCSK_KEX2_1	193	195	PF00082	0.537
CLV_PCSK_KEX2_1	2024	2026	PF00082	0.419
CLV_PCSK_KEX2_1	213	215	PF00082	0.369
CLV_PCSK_KEX2_1	33	35	PF00082	0.492
CLV_PCSK_KEX2_1	582	584	PF00082	0.481
CLV_PCSK_KEX2_1	714	716	PF00082	0.604
CLV_PCSK_KEX2_1	774	776	PF00082	0.457
CLV_PCSK_KEX2_1	794	796	PF00082	0.280
CLV_PCSK_KEX2_1	857	859	PF00082	0.408
CLV_PCSK_PC1ET2_1	1017	1019	PF00082	0.580
CLV_PCSK_PC1ET2_1	1023	1025	PF00082	0.464
CLV_PCSK_PC1ET2_1	1844	1846	PF00082	0.627
CLV_PCSK_PC1ET2_1	213	215	PF00082	0.369
CLV_PCSK_PC1ET2_1	33	35	PF00082	0.492
CLV_PCSK_PC1ET2_1	582	584	PF00082	0.481
CLV_PCSK_SKI1_1	1224	1228	PF00082	0.457
CLV_PCSK_SKI1_1	1309	1313	PF00082	0.443
CLV_PCSK_SKI1_1	1366	1370	PF00082	0.533
CLV_PCSK_SKI1_1	17	21	PF00082	0.480
CLV_PCSK_SKI1_1	1844	1848	PF00082	0.590
CLV_PCSK_SKI1_1	1992	1996	PF00082	0.553
CLV_PCSK_SKI1_1	2002	2006	PF00082	0.327
CLV_PCSK_SKI1_1	330	334	PF00082	0.430
CLV_PCSK_SKI1_1	383	387	PF00082	0.454
CLV_PCSK_SKI1_1	39	43	PF00082	0.476
CLV_PCSK_SKI1_1	569	573	PF00082	0.382
CLV_PCSK_SKI1_1	574	578	PF00082	0.404
CLV_PCSK_SKI1_1	624	628	PF00082	0.478
CLV_PCSK_SKI1_1	633	637	PF00082	0.521
CLV_PCSK_SKI1_1	71	75	PF00082	0.519
CLV_PCSK_SKI1_1	763	767	PF00082	0.522
CLV_PCSK_SKI1_1	775	779	PF00082	0.336
CLV_PCSK_SKI1_1	85	89	PF00082	0.393
CLV_PCSK_SKI1_1	972	976	PF00082	0.237
CLV_Separin_Metazoa	1221	1225	PF03568	0.490
CLV_Separin_Metazoa	1367	1371	PF03568	0.572
DEG_APCC_DBOX_1	1268	1276	PF00400	0.508
DEG_APCC_DBOX_1	1365	1373	PF00400	0.568
DEG_APCC_DBOX_1	2023	2031	PF00400	0.386
DEG_APCC_DBOX_1	222	230	PF00400	0.509
DEG_SPOP_SBC_1	253	257	PF00917	0.239
DOC_ANK_TNKS_1	1611	1618	PF00023	0.318
DOC_CDC14_PxL_1	1800	1808	PF14671	0.505
DOC_CYCLIN_RxL_1	1268	1278	PF00134	0.505
DOC_CYCLIN_RxL_1	769	781	PF00134	0.336
DOC_CYCLIN_RxL_1	82	89	PF00134	0.481
DOC_CYCLIN_yCln2_LP_2	626	629	PF00134	0.468
DOC_MAPK_DCC_7	460	470	PF00069	0.434
DOC_MAPK_gen_1	1269	1276	PF00069	0.470
DOC_MAPK_gen_1	1651	1661	PF00069	0.488
DOC_MAPK_gen_1	387	394	PF00069	0.463
DOC_MAPK_gen_1	510	518	PF00069	0.496
DOC_MAPK_gen_1	806	815	PF00069	0.314
DOC_MAPK_gen_1	857	865	PF00069	0.459
DOC_MAPK_HePTP_8	1547	1559	PF00069	0.431
DOC_MAPK_MEF2A_6	1269	1276	PF00069	0.508
DOC_MAPK_MEF2A_6	1454	1463	PF00069	0.424
DOC_MAPK_MEF2A_6	1550	1559	PF00069	0.524
DOC_MAPK_MEF2A_6	1573	1581	PF00069	0.268
DOC_MAPK_MEF2A_6	1795	1802	PF00069	0.427
DOC_MAPK_MEF2A_6	387	394	PF00069	0.364
DOC_MAPK_MEF2A_6	510	518	PF00069	0.560
DOC_MAPK_MEF2A_6	85	92	PF00069	0.451
DOC_MAPK_MEF2A_6	857	865	PF00069	0.477
DOC_MAPK_NFAT4_5	85	93	PF00069	0.477
DOC_MAPK_RevD_3	1705	1721	PF00069	0.482
DOC_PIKK_1	1759	1767	PF02985	0.589
DOC_PP2B_LxvP_1	1353	1356	PF13499	0.473
DOC_PP2B_LxvP_1	470	473	PF13499	0.429
DOC_PP2B_LxvP_1	626	629	PF13499	0.468
DOC_PP2B_LxvP_1	891	894	PF13499	0.404
DOC_PP4_FxxP_1	476	479	PF00568	0.594
DOC_PP4_FxxP_1	563	566	PF00568	0.472
DOC_PP4_MxPP_1	1536	1539	PF00568	0.455
DOC_SPAK_OSR1_1	1009	1013	PF12202	0.261
DOC_USP7_MATH_1	1085	1089	PF00917	0.372
DOC_USP7_MATH_1	1208	1212	PF00917	0.431
DOC_USP7_MATH_1	1230	1234	PF00917	0.509
DOC_USP7_MATH_1	130	134	PF00917	0.526
DOC_USP7_MATH_1	149	153	PF00917	0.651
DOC_USP7_MATH_1	1652	1656	PF00917	0.508
DOC_USP7_MATH_1	1668	1672	PF00917	0.589
DOC_USP7_MATH_1	1688	1692	PF00917	0.538
DOC_USP7_MATH_1	1697	1701	PF00917	0.322
DOC_USP7_MATH_1	1853	1857	PF00917	0.650
DOC_USP7_MATH_1	366	370	PF00917	0.478
DOC_USP7_MATH_1	447	451	PF00917	0.485
DOC_USP7_MATH_1	452	456	PF00917	0.481
DOC_USP7_MATH_1	581	585	PF00917	0.522
DOC_USP7_MATH_1	677	681	PF00917	0.515
DOC_USP7_MATH_1	759	763	PF00917	0.573
DOC_USP7_MATH_1	777	781	PF00917	0.564
DOC_USP7_MATH_1	895	899	PF00917	0.518
DOC_USP7_MATH_1	904	908	PF00917	0.491
DOC_USP7_MATH_1	987	991	PF00917	0.475
DOC_USP7_UBL2_3	800	804	PF12436	0.639
DOC_WW_Pin1_4	10	15	PF00397	0.316
DOC_WW_Pin1_4	1023	1028	PF00397	0.522
DOC_WW_Pin1_4	1165	1170	PF00397	0.434
DOC_WW_Pin1_4	1251	1256	PF00397	0.538
DOC_WW_Pin1_4	1375	1380	PF00397	0.424
DOC_WW_Pin1_4	1529	1534	PF00397	0.444
DOC_WW_Pin1_4	1644	1649	PF00397	0.530
DOC_WW_Pin1_4	1670	1675	PF00397	0.655
DOC_WW_Pin1_4	1682	1687	PF00397	0.551
DOC_WW_Pin1_4	1793	1798	PF00397	0.480
DOC_WW_Pin1_4	1892	1897	PF00397	0.534
DOC_WW_Pin1_4	1983	1988	PF00397	0.588
DOC_WW_Pin1_4	2012	2017	PF00397	0.404
DOC_WW_Pin1_4	2046	2051	PF00397	0.505
DOC_WW_Pin1_4	334	339	PF00397	0.398
DOC_WW_Pin1_4	437	442	PF00397	0.561
DOC_WW_Pin1_4	716	721	PF00397	0.658
DOC_WW_Pin1_4	993	998	PF00397	0.358
LIG_14-3-3_CanoR_1	1239	1249	PF00244	0.354
LIG_14-3-3_CanoR_1	129	135	PF00244	0.521
LIG_14-3-3_CanoR_1	1373	1379	PF00244	0.430
LIG_14-3-3_CanoR_1	1550	1554	PF00244	0.398
LIG_14-3-3_CanoR_1	1651	1661	PF00244	0.541
LIG_14-3-3_CanoR_1	1754	1762	PF00244	0.606
LIG_14-3-3_CanoR_1	1971	1981	PF00244	0.573
LIG_14-3-3_CanoR_1	1992	2001	PF00244	0.526
LIG_14-3-3_CanoR_1	2025	2031	PF00244	0.302
LIG_14-3-3_CanoR_1	555	559	PF00244	0.459
LIG_14-3-3_CanoR_1	583	592	PF00244	0.513
LIG_14-3-3_CanoR_1	630	636	PF00244	0.478
LIG_14-3-3_CanoR_1	646	651	PF00244	0.361
LIG_14-3-3_CanoR_1	71	81	PF00244	0.472
LIG_14-3-3_CanoR_1	753	759	PF00244	0.613
LIG_14-3-3_CanoR_1	763	768	PF00244	0.478
LIG_14-3-3_CanoR_1	806	815	PF00244	0.477
LIG_14-3-3_CanoR_1	823	828	PF00244	0.441
LIG_APCC_ABBA_1	1871	1876	PF00400	0.437
LIG_APCC_ABBA_1	81	86	PF00400	0.480
LIG_BIR_II_1	1	5	PF00653	0.357
LIG_BIR_III_2	1936	1940	PF00653	0.492
LIG_BIR_III_2	381	385	PF00653	0.454
LIG_BIR_III_4	966	970	PF00653	0.381
LIG_BRCT_BRCA1_1	1944	1948	PF00533	0.545
LIG_BRCT_BRCA1_1	2059	2063	PF00533	0.406
LIG_BRCT_BRCA1_1	585	589	PF00533	0.516
LIG_BRCT_BRCA1_1	825	829	PF00533	0.498
LIG_CaM_NSCaTE_8	754	761	PF13499	0.366
LIG_Clathr_ClatBox_1	1658	1662	PF01394	0.418
LIG_Clathr_ClatBox_1	19	23	PF01394	0.508
LIG_EH1_1	1183	1191	PF00400	0.234
LIG_FHA_1	1006	1012	PF00498	0.465
LIG_FHA_1	1128	1134	PF00498	0.400
LIG_FHA_1	1731	1737	PF00498	0.458
LIG_FHA_1	1812	1818	PF00498	0.427
LIG_FHA_1	1913	1919	PF00498	0.513
LIG_FHA_1	1933	1939	PF00498	0.203
LIG_FHA_1	1993	1999	PF00498	0.455
LIG_FHA_1	2017	2023	PF00498	0.534
LIG_FHA_1	2047	2053	PF00498	0.424
LIG_FHA_1	254	260	PF00498	0.504
LIG_FHA_1	347	353	PF00498	0.277
LIG_FHA_1	373	379	PF00498	0.450
LIG_FHA_1	517	523	PF00498	0.467
LIG_FHA_1	551	557	PF00498	0.494
LIG_FHA_1	560	566	PF00498	0.425
LIG_FHA_1	588	594	PF00498	0.451
LIG_FHA_1	645	651	PF00498	0.439
LIG_FHA_1	683	689	PF00498	0.400
LIG_FHA_1	723	729	PF00498	0.504
LIG_FHA_1	78	84	PF00498	0.421
LIG_FHA_1	808	814	PF00498	0.381
LIG_FHA_1	832	838	PF00498	0.417
LIG_FHA_1	924	930	PF00498	0.394
LIG_FHA_2	1050	1056	PF00498	0.532
LIG_FHA_2	1162	1168	PF00498	0.357
LIG_FHA_2	1189	1195	PF00498	0.238
LIG_FHA_2	121	127	PF00498	0.538
LIG_FHA_2	1292	1298	PF00498	0.362
LIG_FHA_2	1325	1331	PF00498	0.497
LIG_FHA_2	1539	1545	PF00498	0.609
LIG_FHA_2	1645	1651	PF00498	0.541
LIG_FHA_2	1761	1767	PF00498	0.569
LIG_FHA_2	55	61	PF00498	0.686
LIG_FHA_2	881	887	PF00498	0.402
LIG_FHA_2	941	947	PF00498	0.513
LIG_FHA_2	961	967	PF00498	0.171
LIG_GBD_Chelix_1	592	600	PF00786	0.451
LIG_GBD_Chelix_1	824	832	PF00786	0.236
LIG_HCF-1_HBM_1	706	709	PF13415	0.317
LIG_Integrin_RGD_1	715	717	PF01839	0.641
LIG_Integrin_RGD_1	968	970	PF01839	0.505
LIG_LIR_Apic_2	1066	1070	PF02991	0.259
LIG_LIR_Apic_2	475	479	PF02991	0.604
LIG_LIR_Apic_2	560	566	PF02991	0.476
LIG_LIR_Gen_1	1634	1644	PF02991	0.449
LIG_LIR_Gen_1	1703	1713	PF02991	0.494
LIG_LIR_Gen_1	1728	1736	PF02991	0.602
LIG_LIR_Gen_1	1796	1806	PF02991	0.457
LIG_LIR_Gen_1	1945	1956	PF02991	0.520
LIG_LIR_Gen_1	2049	2058	PF02991	0.382
LIG_LIR_Gen_1	288	297	PF02991	0.239
LIG_LIR_Gen_1	485	495	PF02991	0.541
LIG_LIR_Gen_1	586	596	PF02991	0.430
LIG_LIR_Gen_1	927	936	PF02991	0.425
LIG_LIR_Gen_1	954	962	PF02991	0.380
LIG_LIR_Nem_3	1634	1639	PF02991	0.450
LIG_LIR_Nem_3	1700	1705	PF02991	0.408
LIG_LIR_Nem_3	1728	1732	PF02991	0.561
LIG_LIR_Nem_3	1780	1785	PF02991	0.421
LIG_LIR_Nem_3	1796	1802	PF02991	0.380
LIG_LIR_Nem_3	1838	1842	PF02991	0.293
LIG_LIR_Nem_3	1945	1951	PF02991	0.509
LIG_LIR_Nem_3	2049	2054	PF02991	0.435
LIG_LIR_Nem_3	288	293	PF02991	0.343
LIG_LIR_Nem_3	40	45	PF02991	0.558
LIG_LIR_Nem_3	482	487	PF02991	0.464
LIG_LIR_Nem_3	541	547	PF02991	0.384
LIG_LIR_Nem_3	586	592	PF02991	0.437
LIG_LIR_Nem_3	898	903	PF02991	0.433
LIG_LIR_Nem_3	927	933	PF02991	0.424
LIG_LIR_Nem_3	954	958	PF02991	0.382
LIG_LYPXL_SIV_4	997	1005	PF13949	0.481
LIG_NRBOX	1271	1277	PF00104	0.420
LIG_NRBOX	1478	1484	PF00104	0.338
LIG_NRBOX	1576	1582	PF00104	0.489
LIG_NRBOX	175	181	PF00104	0.486
LIG_NRBOX	225	231	PF00104	0.499
LIG_NRBOX	357	363	PF00104	0.434
LIG_NRBOX	567	573	PF00104	0.363
LIG_NRBOX	615	621	PF00104	0.490
LIG_PCNA_yPIPBox_3	1304	1312	PF02747	0.300
LIG_Pex14_1	429	433	PF04695	0.459
LIG_Pex14_1	585	589	PF04695	0.475
LIG_Pex14_2	815	819	PF04695	0.481
LIG_Rb_LxCxE_1	1655	1673	PF01857	0.468
LIG_Rb_LxCxE_1	408	419	PF01857	0.517
LIG_RPA_C_Fungi	963	975	PF08784	0.236
LIG_SH2_CRK	1083	1087	PF00017	0.239
LIG_SH2_CRK	1636	1640	PF00017	0.546
LIG_SH2_CRK	2055	2059	PF00017	0.416
LIG_SH2_CRK	548	552	PF00017	0.433
LIG_SH2_GRB2like	1419	1422	PF00017	0.286
LIG_SH2_NCK_1	903	907	PF00017	0.519
LIG_SH2_PTP2	236	239	PF00017	0.231
LIG_SH2_SRC	903	906	PF00017	0.520
LIG_SH2_STAP1	100	104	PF00017	0.482
LIG_SH2_STAP1	1209	1213	PF00017	0.266
LIG_SH2_STAP1	1241	1245	PF00017	0.575
LIG_SH2_STAP1	1636	1640	PF00017	0.427
LIG_SH2_STAP1	487	491	PF00017	0.415
LIG_SH2_STAP1	709	713	PF00017	0.558
LIG_SH2_STAT3	1209	1212	PF00017	0.266
LIG_SH2_STAT3	1723	1726	PF00017	0.335
LIG_SH2_STAT5	1241	1244	PF00017	0.594
LIG_SH2_STAT5	1636	1639	PF00017	0.525
LIG_SH2_STAT5	1723	1726	PF00017	0.514
LIG_SH2_STAT5	1792	1795	PF00017	0.447
LIG_SH2_STAT5	1799	1802	PF00017	0.398
LIG_SH2_STAT5	1913	1916	PF00017	0.506
LIG_SH2_STAT5	236	239	PF00017	0.458
LIG_SH2_STAT5	266	269	PF00017	0.494
LIG_SH2_STAT5	302	305	PF00017	0.372
LIG_SH2_STAT5	548	551	PF00017	0.460
LIG_SH2_STAT5	602	605	PF00017	0.274
LIG_SH2_STAT5	867	870	PF00017	0.349
LIG_SH2_STAT5	939	942	PF00017	0.432
LIG_SH2_STAT5	998	1001	PF00017	0.488
LIG_SH3_1	459	465	PF00018	0.439
LIG_SH3_3	1419	1425	PF00018	0.283
LIG_SH3_3	435	441	PF00018	0.597
LIG_SH3_3	459	465	PF00018	0.480
LIG_SH3_3	471	477	PF00018	0.473
LIG_SH3_3	784	790	PF00018	0.341
LIG_SH3_CIN85_PxpxPR_1	1987	1992	PF14604	0.299
LIG_Sin3_3	1270	1277	PF02671	0.238
LIG_Sin3_3	1491	1498	PF02671	0.287
LIG_Sin3_3	177	184	PF02671	0.526
LIG_Sin3_3	445	452	PF02671	0.420
LIG_SUMO_SIM_anti_2	1126	1134	PF11976	0.516
LIG_SUMO_SIM_anti_2	1225	1231	PF11976	0.532
LIG_SUMO_SIM_anti_2	247	252	PF11976	0.492
LIG_SUMO_SIM_anti_2	356	362	PF11976	0.393
LIG_SUMO_SIM_par_1	1129	1134	PF11976	0.455
LIG_SUMO_SIM_par_1	1187	1194	PF11976	0.392
LIG_SUMO_SIM_par_1	1225	1231	PF11976	0.532
LIG_SUMO_SIM_par_1	1272	1278	PF11976	0.518
LIG_SUMO_SIM_par_1	1429	1434	PF11976	0.313
LIG_SUMO_SIM_par_1	1820	1826	PF11976	0.271
LIG_SUMO_SIM_par_1	225	231	PF11976	0.380
LIG_SUMO_SIM_par_1	375	381	PF11976	0.482
LIG_SUMO_SIM_par_1	932	938	PF11976	0.427
LIG_TRAF2_1	1218	1221	PF00917	0.260
LIG_TRAF2_1	1349	1352	PF00917	0.274
LIG_TRAF2_1	1541	1544	PF00917	0.613
LIG_TRAF2_1	1757	1760	PF00917	0.523
LIG_TRAF2_1	607	610	PF00917	0.474
LIG_TRAF2_1	747	750	PF00917	0.632
LIG_TRAF2_1	918	921	PF00917	0.513
LIG_TRFH_1	350	354	PF08558	0.260
LIG_TYR_ITIM	1417	1422	PF00017	0.288
LIG_TYR_ITIM	546	551	PF00017	0.511
LIG_UBA3_1	1998	2005	PF00899	0.456
LIG_UBA3_1	226	234	PF00899	0.461
LIG_UBA3_1	323	330	PF00899	0.362
LIG_UBA3_1	490	494	PF00899	0.498
LIG_UBA3_1	576	582	PF00899	0.424
LIG_WRC_WIRS_1	547	552	PF05994	0.510
LIG_WRC_WIRS_1	602	607	PF05994	0.247
LIG_WW_1	628	631	PF00397	0.532
LIG_WW_3	627	631	PF00397	0.526
MOD_CDK_SPxxK_3	10	17	PF00069	0.313
MOD_CDK_SPxxK_3	1644	1651	PF00069	0.522
MOD_CDK_SPxxK_3	1670	1677	PF00069	0.413
MOD_CDK_SPxxK_3	1985	1992	PF00069	0.305
MOD_CK1_1	10	16	PF00069	0.439
MOD_CK1_1	1107	1113	PF00069	0.400
MOD_CK1_1	1377	1383	PF00069	0.463
MOD_CK1_1	1700	1706	PF00069	0.231
MOD_CK1_1	1856	1862	PF00069	0.483
MOD_CK1_1	1863	1869	PF00069	0.342
MOD_CK1_1	1892	1898	PF00069	0.491
MOD_CK1_1	1961	1967	PF00069	0.462
MOD_CK1_1	2028	2034	PF00069	0.511
MOD_CK1_1	252	258	PF00069	0.509
MOD_CK1_1	369	375	PF00069	0.525
MOD_CK1_1	439	445	PF00069	0.595
MOD_CK1_1	450	456	PF00069	0.555
MOD_CK1_1	557	563	PF00069	0.417
MOD_CK1_1	588	594	PF00069	0.368
MOD_CK1_1	604	610	PF00069	0.503
MOD_CK1_1	673	679	PF00069	0.461
MOD_CK1_1	802	808	PF00069	0.389
MOD_CK1_1	991	997	PF00069	0.478
MOD_CK2_1	1049	1055	PF00069	0.519
MOD_CK2_1	1134	1140	PF00069	0.408
MOD_CK2_1	1188	1194	PF00069	0.244
MOD_CK2_1	120	126	PF00069	0.443
MOD_CK2_1	1346	1352	PF00069	0.259
MOD_CK2_1	1524	1530	PF00069	0.575
MOD_CK2_1	1538	1544	PF00069	0.564
MOD_CK2_1	1644	1650	PF00069	0.443
MOD_CK2_1	1753	1759	PF00069	0.462
MOD_CK2_1	428	434	PF00069	0.563
MOD_CK2_1	532	538	PF00069	0.573
MOD_CK2_1	54	60	PF00069	0.678
MOD_CK2_1	604	610	PF00069	0.451
MOD_CK2_1	744	750	PF00069	0.612
MOD_CK2_1	880	886	PF00069	0.355
MOD_CK2_1	940	946	PF00069	0.438
MOD_Cter_Amidation	1021	1024	PF01082	0.314
MOD_Cter_Amidation	1522	1525	PF01082	0.556
MOD_Cter_Amidation	1663	1666	PF01082	0.294
MOD_Cter_Amidation	1718	1721	PF01082	0.589
MOD_Cter_Amidation	1842	1845	PF01082	0.607
MOD_GlcNHglycan	1158	1161	PF01048	0.602
MOD_GlcNHglycan	117	120	PF01048	0.583
MOD_GlcNHglycan	1261	1264	PF01048	0.533
MOD_GlcNHglycan	1301	1304	PF01048	0.567
MOD_GlcNHglycan	1424	1428	PF01048	0.491
MOD_GlcNHglycan	1432	1436	PF01048	0.513
MOD_GlcNHglycan	157	160	PF01048	0.547
MOD_GlcNHglycan	1613	1616	PF01048	0.463
MOD_GlcNHglycan	1690	1693	PF01048	0.491
MOD_GlcNHglycan	1713	1716	PF01048	0.569
MOD_GlcNHglycan	1756	1759	PF01048	0.509
MOD_GlcNHglycan	1863	1866	PF01048	0.451
MOD_GlcNHglycan	1903	1906	PF01048	0.511
MOD_GlcNHglycan	194	197	PF01048	0.493
MOD_GlcNHglycan	1974	1977	PF01048	0.554
MOD_GlcNHglycan	2031	2034	PF01048	0.510
MOD_GlcNHglycan	2043	2046	PF01048	0.457
MOD_GlcNHglycan	2059	2062	PF01048	0.411
MOD_GlcNHglycan	251	254	PF01048	0.439
MOD_GlcNHglycan	368	371	PF01048	0.478
MOD_GlcNHglycan	441	444	PF01048	0.512
MOD_GlcNHglycan	445	448	PF01048	0.585
MOD_GlcNHglycan	523	526	PF01048	0.306
MOD_GlcNHglycan	57	60	PF01048	0.673
MOD_GlcNHglycan	674	678	PF01048	0.401
MOD_GlcNHglycan	679	682	PF01048	0.369
MOD_GlcNHglycan	746	749	PF01048	0.427
MOD_GlcNHglycan	843	846	PF01048	0.471
MOD_GlcNHglycan	874	877	PF01048	0.434
MOD_GlcNHglycan	905	909	PF01048	0.484
MOD_GlcNHglycan	94	98	PF01048	0.443
MOD_GlcNHglycan	990	993	PF01048	0.402
MOD_GSK3_1	1104	1111	PF00069	0.512
MOD_GSK3_1	1119	1126	PF00069	0.455
MOD_GSK3_1	1161	1168	PF00069	0.357
MOD_GSK3_1	1184	1191	PF00069	0.494
MOD_GSK3_1	1231	1238	PF00069	0.492
MOD_GSK3_1	1332	1339	PF00069	0.474
MOD_GSK3_1	1377	1384	PF00069	0.545
MOD_GSK3_1	1493	1500	PF00069	0.457
MOD_GSK3_1	1513	1520	PF00069	0.567
MOD_GSK3_1	1628	1635	PF00069	0.462
MOD_GSK3_1	1688	1695	PF00069	0.443
MOD_GSK3_1	1811	1818	PF00069	0.398
MOD_GSK3_1	1856	1863	PF00069	0.608
MOD_GSK3_1	1877	1884	PF00069	0.493
MOD_GSK3_1	192	199	PF00069	0.293
MOD_GSK3_1	1938	1945	PF00069	0.485
MOD_GSK3_1	1958	1965	PF00069	0.316
MOD_GSK3_1	1972	1979	PF00069	0.378
MOD_GSK3_1	1981	1988	PF00069	0.432
MOD_GSK3_1	2012	2019	PF00069	0.452
MOD_GSK3_1	2025	2032	PF00069	0.546
MOD_GSK3_1	2046	2053	PF00069	0.475
MOD_GSK3_1	249	256	PF00069	0.478
MOD_GSK3_1	369	376	PF00069	0.421
MOD_GSK3_1	439	446	PF00069	0.535
MOD_GSK3_1	450	457	PF00069	0.580
MOD_GSK3_1	546	553	PF00069	0.482
MOD_GSK3_1	55	62	PF00069	0.625
MOD_GSK3_1	581	588	PF00069	0.537
MOD_GSK3_1	673	680	PF00069	0.576
MOD_GSK3_1	72	79	PF00069	0.561
MOD_GSK3_1	744	751	PF00069	0.546
MOD_GSK3_1	759	766	PF00069	0.406
MOD_GSK3_1	807	814	PF00069	0.474
MOD_GSK3_1	849	856	PF00069	0.559
MOD_GSK3_1	987	994	PF00069	0.507
MOD_LATS_1	1237	1243	PF00433	0.302
MOD_N-GLC_1	1420	1425	PF02516	0.469
MOD_N-GLC_1	1631	1636	PF02516	0.477
MOD_N-GLC_1	1932	1937	PF02516	0.456
MOD_N-GLC_1	1946	1951	PF02516	0.492
MOD_N-GLC_1	1961	1966	PF02516	0.584
MOD_N-GLC_1	677	682	PF02516	0.479
MOD_N-GLC_1	754	759	PF02516	0.420
MOD_N-GLC_2	1929	1931	PF02516	0.494
MOD_N-GLC_2	204	206	PF02516	0.365
MOD_NEK2_1	1005	1010	PF00069	0.485
MOD_NEK2_1	1184	1189	PF00069	0.475
MOD_NEK2_1	1240	1245	PF00069	0.574
MOD_NEK2_1	1324	1329	PF00069	0.361
MOD_NEK2_1	1431	1436	PF00069	0.485
MOD_NEK2_1	1753	1758	PF00069	0.411
MOD_NEK2_1	1785	1790	PF00069	0.455
MOD_NEK2_1	1847	1852	PF00069	0.605
MOD_NEK2_1	1946	1951	PF00069	0.436
MOD_NEK2_1	1972	1977	PF00069	0.548
MOD_NEK2_1	254	259	PF00069	0.454
MOD_NEK2_1	267	272	PF00069	0.455
MOD_NEK2_1	516	521	PF00069	0.471
MOD_NEK2_1	546	551	PF00069	0.497
MOD_NEK2_1	570	575	PF00069	0.407
MOD_NEK2_1	654	659	PF00069	0.502
MOD_NEK2_1	672	677	PF00069	0.580
MOD_NEK2_1	688	693	PF00069	0.528
MOD_NEK2_1	7	12	PF00069	0.345
MOD_NEK2_1	767	772	PF00069	0.534
MOD_NEK2_1	799	804	PF00069	0.537
MOD_NEK2_1	828	833	PF00069	0.476
MOD_NEK2_1	95	100	PF00069	0.511
MOD_NEK2_1	951	956	PF00069	0.367
MOD_NEK2_2	1144	1149	PF00069	0.528
MOD_NEK2_2	1232	1237	PF00069	0.312
MOD_NEK2_2	130	135	PF00069	0.526
MOD_NEK2_2	1319	1324	PF00069	0.225
MOD_NEK2_2	1706	1711	PF00069	0.521
MOD_NEK2_2	2050	2055	PF00069	0.511
MOD_NEK2_2	2059	2064	PF00069	0.481
MOD_NEK2_2	428	433	PF00069	0.452
MOD_NEK2_2	631	636	PF00069	0.558
MOD_NEK2_2	709	714	PF00069	0.603
MOD_NEK2_2	895	900	PF00069	0.237
MOD_PIKK_1	1161	1167	PF00454	0.357
MOD_PIKK_1	1208	1214	PF00454	0.536
MOD_PIKK_1	1256	1262	PF00454	0.326
MOD_PIKK_1	149	155	PF00454	0.428
MOD_PIKK_1	1591	1597	PF00454	0.475
MOD_PIKK_1	1634	1640	PF00454	0.423
MOD_PIKK_1	1847	1853	PF00454	0.531
MOD_PIKK_1	1946	1952	PF00454	0.504
MOD_PIKK_1	1962	1968	PF00454	0.603
MOD_PIKK_1	748	754	PF00454	0.474
MOD_PIKK_1	767	773	PF00454	0.442
MOD_PK_1	646	652	PF00069	0.526
MOD_PKA_1	1524	1530	PF00069	0.623
MOD_PKA_2	1319	1325	PF00069	0.463
MOD_PKA_2	1400	1406	PF00069	0.566
MOD_PKA_2	1549	1555	PF00069	0.536
MOD_PKA_2	1611	1617	PF00069	0.313
MOD_PKA_2	1753	1759	PF00069	0.513
MOD_PKA_2	1760	1766	PF00069	0.564
MOD_PKA_2	192	198	PF00069	0.464
MOD_PKA_2	1972	1978	PF00069	0.602
MOD_PKA_2	538	544	PF00069	0.470
MOD_PKA_2	551	557	PF00069	0.468
MOD_PKA_2	645	651	PF00069	0.363
MOD_PKA_2	77	83	PF00069	0.471
MOD_PKA_2	805	811	PF00069	0.432
MOD_Plk_1	1283	1289	PF00069	0.457
MOD_Plk_1	1431	1437	PF00069	0.532
MOD_Plk_1	1631	1637	PF00069	0.482
MOD_Plk_1	1811	1817	PF00069	0.395
MOD_Plk_1	1946	1952	PF00069	0.400
MOD_Plk_1	372	378	PF00069	0.315
MOD_Plk_1	7	13	PF00069	0.492
MOD_Plk_1	754	760	PF00069	0.544
MOD_Plk_2-3	1049	1055	PF00069	0.273
MOD_Plk_2-3	881	887	PF00069	0.294
MOD_Plk_4	1000	1006	PF00069	0.438
MOD_Plk_4	1111	1117	PF00069	0.494
MOD_Plk_4	1127	1133	PF00069	0.416
MOD_Plk_4	1314	1320	PF00069	0.508
MOD_Plk_4	135	141	PF00069	0.539
MOD_Plk_4	1388	1394	PF00069	0.307
MOD_Plk_4	1654	1660	PF00069	0.469
MOD_Plk_4	1863	1869	PF00069	0.322
MOD_Plk_4	1912	1918	PF00069	0.509
MOD_Plk_4	196	202	PF00069	0.283
MOD_Plk_4	2050	2056	PF00069	0.523
MOD_Plk_4	255	261	PF00069	0.377
MOD_Plk_4	373	379	PF00069	0.542
MOD_Plk_4	428	434	PF00069	0.546
MOD_Plk_4	546	552	PF00069	0.468
MOD_Plk_4	559	565	PF00069	0.307
MOD_Plk_4	588	594	PF00069	0.413
MOD_Plk_4	763	769	PF00069	0.517
MOD_Plk_4	823	829	PF00069	0.490
MOD_Plk_4	895	901	PF00069	0.459
MOD_Plk_4	95	101	PF00069	0.471
MOD_Plk_4	951	957	PF00069	0.407
MOD_ProDKin_1	10	16	PF00069	0.315
MOD_ProDKin_1	1023	1029	PF00069	0.519
MOD_ProDKin_1	1165	1171	PF00069	0.433
MOD_ProDKin_1	1251	1257	PF00069	0.540
MOD_ProDKin_1	1375	1381	PF00069	0.429
MOD_ProDKin_1	1529	1535	PF00069	0.445
MOD_ProDKin_1	1644	1650	PF00069	0.525
MOD_ProDKin_1	1670	1676	PF00069	0.653
MOD_ProDKin_1	1682	1688	PF00069	0.543
MOD_ProDKin_1	1793	1799	PF00069	0.481
MOD_ProDKin_1	1892	1898	PF00069	0.537
MOD_ProDKin_1	1983	1989	PF00069	0.586
MOD_ProDKin_1	2012	2018	PF00069	0.403
MOD_ProDKin_1	2046	2052	PF00069	0.504
MOD_ProDKin_1	334	340	PF00069	0.398
MOD_ProDKin_1	437	443	PF00069	0.565
MOD_ProDKin_1	716	722	PF00069	0.658
MOD_ProDKin_1	993	999	PF00069	0.359
MOD_SUMO_rev_2	1019	1025	PF00179	0.478
MOD_SUMO_rev_2	2044	2050	PF00179	0.525
MOD_SUMO_rev_2	919	924	PF00179	0.535
TRG_DiLeu_BaEn_1	1333	1338	PF01217	0.227
TRG_DiLeu_BaEn_1	1543	1548	PF01217	0.518
TRG_DiLeu_BaEn_1	373	378	PF01217	0.448
TRG_DiLeu_BaEn_2	1366	1372	PF01217	0.522
TRG_DiLeu_BaEn_2	558	564	PF01217	0.414
TRG_DiLeu_BaEn_2	945	951	PF01217	0.369
TRG_DiLeu_BaEn_4	1048	1054	PF01217	0.429
TRG_DiLeu_BaLyEn_6	1268	1273	PF01217	0.512
TRG_DiLeu_BaLyEn_6	1500	1505	PF01217	0.482
TRG_DiLeu_BaLyEn_6	381	386	PF01217	0.448
TRG_DiLeu_LyEn_5	740	745	PF01217	0.418
TRG_ENDOCYTIC_2	1083	1086	PF00928	0.341
TRG_ENDOCYTIC_2	1419	1422	PF00928	0.286
TRG_ENDOCYTIC_2	1636	1639	PF00928	0.542
TRG_ENDOCYTIC_2	1799	1802	PF00928	0.432
TRG_ENDOCYTIC_2	2055	2058	PF00928	0.486
TRG_ENDOCYTIC_2	236	239	PF00928	0.368
TRG_ENDOCYTIC_2	487	490	PF00928	0.418
TRG_ENDOCYTIC_2	547	550	PF00928	0.382
TRG_ENDOCYTIC_2	602	605	PF00928	0.392
TRG_ENDOCYTIC_2	84	87	PF00928	0.384
TRG_ENDOCYTIC_2	953	956	PF00928	0.393
TRG_ER_diArg_1	1077	1080	PF00400	0.445
TRG_ER_diArg_1	1215	1217	PF00400	0.466
TRG_ER_diArg_1	1268	1271	PF00400	0.513
TRG_ER_diArg_1	1501	1504	PF00400	0.537
TRG_ER_diArg_1	1604	1606	PF00400	0.277
TRG_ER_diArg_1	1720	1722	PF00400	0.548
TRG_ER_diArg_1	1971	1974	PF00400	0.424
TRG_ER_diArg_1	713	715	PF00400	0.623
TRG_ER_diArg_1	774	776	PF00400	0.525
TRG_NES_CRM1_1	1278	1290	PF08389	0.509
TRG_NES_CRM1_1	1475	1486	PF08389	0.327
TRG_NES_CRM1_1	228	241	PF08389	0.228
TRG_NES_CRM1_1	82	94	PF08389	0.476
TRG_Pf-PMV_PEXEL_1	1009	1013	PF00026	0.529
TRG_Pf-PMV_PEXEL_1	1095	1099	PF00026	0.507
TRG_Pf-PMV_PEXEL_1	142	146	PF00026	0.629
TRG_Pf-PMV_PEXEL_1	1665	1669	PF00026	0.364
TRG_Pf-PMV_PEXEL_1	2034	2038	PF00026	0.554
TRG_Pf-PMV_PEXEL_1	621	625	PF00026	0.513
TRG_Pf-PMV_PEXEL_1	726	730	PF00026	0.631
TRG_Pf-PMV_PEXEL_1	774	779	PF00026	0.331
TRG_Pf-PMV_PEXEL_1	85	89	PF00026	0.531
TRG_Pf-PMV_PEXEL_1	877	881	PF00026	0.462

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I8Y5	Leptomonas seymouri	42%	78%
A0A1X0PAG8	Trypanosomatidae	23%	83%
A0A3R7KKQ4	Trypanosoma rangeli	24%	83%
A0A3S5H7Y0	Leishmania donovani	75%	80%
A4IAI2	Leishmania infantum	75%	80%
C9ZLQ7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	23%	83%
E9B5K6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	74%	80%
Q4Q2D0	Leishmania major	75%	100%