J domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DnaJ domain containing protein, putative

Species:

Leishmania braziliensis

UniProt:

A4HBD1_LEIBR

TriTrypDb:

LbrM.20.3710 , LBRM2903_200051400

Length:

255

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	10
GO:0110165	cellular anatomical entity	1	10

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Expansion

Sequence features

A4HBD1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HBD1

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	107	109	PF00675	0.455
CLV_NRD_NRD_1	218	220	PF00675	0.656
CLV_NRD_NRD_1	3	5	PF00675	0.434
CLV_NRD_NRD_1	47	49	PF00675	0.270
CLV_NRD_NRD_1	83	85	PF00675	0.402
CLV_PCSK_KEX2_1	107	109	PF00082	0.455
CLV_PCSK_KEX2_1	218	220	PF00082	0.593
CLV_PCSK_KEX2_1	3	5	PF00082	0.434
CLV_PCSK_KEX2_1	49	51	PF00082	0.339
CLV_PCSK_KEX2_1	83	85	PF00082	0.402

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1ILG9	Leptomonas seymouri	73%	98%
A0A0S4KRJ1	Bodo saltans	44%	100%
A0A1X0PA98	Trypanosomatidae	55%	100%
A0A3S7X8J5	Leishmania donovani	84%	96%
A0A422NVC0	Trypanosoma rangeli	55%	100%
A4IAH9	Leishmania infantum	84%	96%
C9ZLR0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	54%	100%
E9B5K3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	97%
Q4Q2D3	Leishmania major	82%	100%

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