Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania braziliensis

UniProt:

A4HB94_LEIBR

TriTrypDb:

LbrM.20.3340 , LBRM2903_200047300

Length:

500

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HB94

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HB94

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	418	422	PF00656	0.568
CLV_NRD_NRD_1	246	248	PF00675	0.709
CLV_NRD_NRD_1	257	259	PF00675	0.501
CLV_NRD_NRD_1	322	324	PF00675	0.561
CLV_NRD_NRD_1	345	347	PF00675	0.688
CLV_NRD_NRD_1	457	459	PF00675	0.576
CLV_PCSK_FUR_1	455	459	PF00082	0.577
CLV_PCSK_KEX2_1	246	248	PF00082	0.755
CLV_PCSK_KEX2_1	257	259	PF00082	0.501
CLV_PCSK_KEX2_1	457	459	PF00082	0.576
CLV_PCSK_KEX2_1	84	86	PF00082	0.634
CLV_PCSK_PC1ET2_1	84	86	PF00082	0.764
CLV_PCSK_SKI1_1	423	427	PF00082	0.790
CLV_PCSK_SKI1_1	99	103	PF00082	0.619
DEG_COP1_1	380	389	PF00400	0.565
DEG_SCF_FBW7_1	443	448	PF00400	0.553
DEG_SPOP_SBC_1	142	146	PF00917	0.534
DOC_CKS1_1	267	272	PF01111	0.587
DOC_CKS1_1	446	451	PF01111	0.626
DOC_PP4_FxxP_1	305	308	PF00568	0.579
DOC_USP7_MATH_1	129	133	PF00917	0.636
DOC_USP7_MATH_1	2	6	PF00917	0.468
DOC_USP7_MATH_1	278	282	PF00917	0.568
DOC_USP7_MATH_1	359	363	PF00917	0.699
DOC_USP7_MATH_1	407	411	PF00917	0.631
DOC_USP7_MATH_1	496	500	PF00917	0.545
DOC_WW_Pin1_4	108	113	PF00397	0.803
DOC_WW_Pin1_4	217	222	PF00397	0.575
DOC_WW_Pin1_4	266	271	PF00397	0.769
DOC_WW_Pin1_4	276	281	PF00397	0.720
DOC_WW_Pin1_4	285	290	PF00397	0.577
DOC_WW_Pin1_4	316	321	PF00397	0.825
DOC_WW_Pin1_4	379	384	PF00397	0.771
DOC_WW_Pin1_4	441	446	PF00397	0.667
DOC_WW_Pin1_4	475	480	PF00397	0.594
DOC_WW_Pin1_4	492	497	PF00397	0.575
DOC_WW_Pin1_4	73	78	PF00397	0.726
LIG_14-3-3_CanoR_1	154	164	PF00244	0.707
LIG_14-3-3_CanoR_1	183	191	PF00244	0.646
LIG_14-3-3_CanoR_1	31	37	PF00244	0.549
LIG_14-3-3_CanoR_1	436	446	PF00244	0.594
LIG_14-3-3_CanoR_1	471	479	PF00244	0.588
LIG_Actin_WH2_2	230	248	PF00022	0.539
LIG_BIR_II_1	1	5	PF00653	0.581
LIG_BIR_III_1	1	5	PF00653	0.741
LIG_BIR_III_3	1	5	PF00653	0.581
LIG_BRCT_BRCA1_1	157	161	PF00533	0.644
LIG_BRCT_BRCA1_1	352	356	PF00533	0.752
LIG_BRCT_BRCA1_1	364	368	PF00533	0.625
LIG_BRCT_BRCA1_1	370	374	PF00533	0.530
LIG_BRCT_BRCA1_1	410	414	PF00533	0.805
LIG_BRCT_BRCA1_1	75	79	PF00533	0.725
LIG_Clathr_ClatBox_1	78	82	PF01394	0.731
LIG_CtBP_PxDLS_1	308	312	PF00389	0.578
LIG_FHA_1	143	149	PF00498	0.510
LIG_FHA_1	267	273	PF00498	0.602
LIG_FHA_1	280	286	PF00498	0.599
LIG_FHA_1	395	401	PF00498	0.706
LIG_FHA_1	96	102	PF00498	0.715
LIG_FHA_2	158	164	PF00498	0.697
LIG_FHA_2	176	182	PF00498	0.657
LIG_FHA_2	218	224	PF00498	0.663
LIG_FHA_2	416	422	PF00498	0.571
LIG_LIR_Apic_2	302	308	PF02991	0.577
LIG_LIR_Gen_1	372	383	PF02991	0.639
LIG_LIR_Gen_1	38	48	PF02991	0.592
LIG_LIR_Nem_3	158	164	PF02991	0.623
LIG_LIR_Nem_3	372	378	PF02991	0.638
LIG_LIR_Nem_3	38	43	PF02991	0.583
LIG_MYND_1	207	211	PF01753	0.835
LIG_MYND_1	217	221	PF01753	0.656
LIG_SH2_CRK	164	168	PF00017	0.712
LIG_SH2_CRK	75	79	PF00017	0.725
LIG_SH2_STAT5	152	155	PF00017	0.696
LIG_SH3_3	106	112	PF00018	0.656
LIG_SH3_3	123	129	PF00018	0.489
LIG_SH3_3	200	206	PF00018	0.729
LIG_SH3_3	208	214	PF00018	0.803
LIG_SH3_3	264	270	PF00018	0.825
LIG_SH3_3	440	446	PF00018	0.659
LIG_SH3_3	473	479	PF00018	0.585
LIG_SH3_3	490	496	PF00018	0.476
LIG_SUMO_SIM_par_1	306	312	PF11976	0.578
MOD_CDK_SPK_2	445	450	PF00069	0.554
MOD_CDK_SPxxK_3	316	323	PF00069	0.625
MOD_CK1_1	132	138	PF00069	0.743
MOD_CK1_1	141	147	PF00069	0.571
MOD_CK1_1	35	41	PF00069	0.584
MOD_CK1_1	350	356	PF00069	0.665
MOD_CK1_1	362	368	PF00069	0.718
MOD_CK1_1	381	387	PF00069	0.492
MOD_CK1_1	402	408	PF00069	0.706
MOD_CK1_1	441	447	PF00069	0.691
MOD_CK1_1	464	470	PF00069	0.576
MOD_CK1_1	492	498	PF00069	0.542
MOD_CK1_1	67	73	PF00069	0.475
MOD_CK2_1	157	163	PF00069	0.711
MOD_CK2_1	175	181	PF00069	0.564
MOD_CK2_1	400	406	PF00069	0.600
MOD_Cter_Amidation	455	458	PF01082	0.578
MOD_GlcNHglycan	136	139	PF01048	0.815
MOD_GlcNHglycan	172	175	PF01048	0.583
MOD_GlcNHglycan	198	201	PF01048	0.595
MOD_GlcNHglycan	21	24	PF01048	0.762
MOD_GlcNHglycan	226	229	PF01048	0.556
MOD_GlcNHglycan	241	244	PF01048	0.538
MOD_GlcNHglycan	252	255	PF01048	0.734
MOD_GlcNHglycan	365	368	PF01048	0.658
MOD_GlcNHglycan	391	394	PF01048	0.794
MOD_GlcNHglycan	406	410	PF01048	0.574
MOD_GlcNHglycan	466	469	PF01048	0.626
MOD_GlcNHglycan	52	56	PF01048	0.546
MOD_GSK3_1	129	136	PF00069	0.758
MOD_GSK3_1	138	145	PF00069	0.606
MOD_GSK3_1	26	33	PF00069	0.691
MOD_GSK3_1	272	279	PF00069	0.820
MOD_GSK3_1	291	298	PF00069	0.505
MOD_GSK3_1	303	310	PF00069	0.528
MOD_GSK3_1	355	362	PF00069	0.740
MOD_GSK3_1	363	370	PF00069	0.582
MOD_GSK3_1	373	380	PF00069	0.538
MOD_GSK3_1	381	388	PF00069	0.650
MOD_GSK3_1	401	408	PF00069	0.588
MOD_GSK3_1	415	422	PF00069	0.570
MOD_GSK3_1	423	430	PF00069	0.712
MOD_GSK3_1	437	444	PF00069	0.528
MOD_GSK3_1	492	499	PF00069	0.541
MOD_N-GLC_1	326	331	PF02516	0.577
MOD_N-GLC_1	464	469	PF02516	0.618
MOD_N-GLC_1	64	69	PF02516	0.579
MOD_NEK2_1	226	231	PF00069	0.623
MOD_NEK2_1	368	373	PF00069	0.759
MOD_NEK2_1	400	405	PF00069	0.827
MOD_PIKK_1	168	174	PF00454	0.518
MOD_PIKK_1	326	332	PF00454	0.612
MOD_PKA_2	130	136	PF00069	0.703
MOD_PKA_2	224	230	PF00069	0.689
MOD_PKA_2	30	36	PF00069	0.552
MOD_PKA_2	470	476	PF00069	0.587
MOD_Plk_1	326	332	PF00069	0.576
MOD_Plk_1	423	429	PF00069	0.790
MOD_Plk_2-3	394	400	PF00069	0.601
MOD_Plk_4	2	8	PF00069	0.461
MOD_Plk_4	32	38	PF00069	0.755
MOD_Plk_4	369	375	PF00069	0.725
MOD_Plk_4	67	73	PF00069	0.578
MOD_ProDKin_1	108	114	PF00069	0.806
MOD_ProDKin_1	217	223	PF00069	0.575
MOD_ProDKin_1	266	272	PF00069	0.769
MOD_ProDKin_1	276	282	PF00069	0.719
MOD_ProDKin_1	285	291	PF00069	0.579
MOD_ProDKin_1	316	322	PF00069	0.817
MOD_ProDKin_1	379	385	PF00069	0.775
MOD_ProDKin_1	441	447	PF00069	0.668
MOD_ProDKin_1	475	481	PF00069	0.595
MOD_ProDKin_1	492	498	PF00069	0.575
MOD_ProDKin_1	73	79	PF00069	0.727
MOD_SUMO_rev_2	264	270	PF00179	0.831
MOD_SUMO_rev_2	76	86	PF00179	0.744
MOD_SUMO_rev_2	94	103	PF00179	0.462
TRG_DiLeu_BaLyEn_6	12	17	PF01217	0.451
TRG_DiLeu_BaLyEn_6	208	213	PF01217	0.593
TRG_ENDOCYTIC_2	152	155	PF00928	0.696
TRG_ENDOCYTIC_2	164	167	PF00928	0.503
TRG_ENDOCYTIC_2	75	78	PF00928	0.723
TRG_ER_diArg_1	245	247	PF00400	0.698
TRG_ER_diArg_1	256	258	PF00400	0.499
TRG_ER_diArg_1	455	458	PF00400	0.578
TRG_ER_diArg_1	85	88	PF00400	0.744
TRG_NLS_MonoExtC_3	83	89	PF00514	0.758

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S5H7X8	Leishmania donovani	57%	100%
A4IAE2	Leishmania infantum	56%	100%
E9B5G6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	57%	100%
Q4Q2G9	Leishmania major	58%	100%